Subperiosteal delivery of transforming growth factor beta 1 and human growth hormone from mineralized PCL films
In conclusion, these data demonstrate the feasibility of using bioabsorbable mineral coated membranes to deliver biologically active compounds subperiosteally in a sustained fashion to affect cells at the insertion site, bone marrow, and even growth plate.PMID:38530161 | DOI:10.1002/jbm.a.37684 (Source: Biomed Res)
Source: Biomed Res - March 26, 2024 Category: Research Authors: Matthew B Parlato Jae Sung Lee David G Belair Gianluca Fontana Ellen Leiferman Rewais Hanna Connie Chamberlain Erik A Ranheim William L Murphy Matthew A Halanski Source Type: research
Comparing Effectiveness and Safety of Intravenous Atropine with Topical Tetracaine in Preventing and Relieving Oculocardiac Reflex in Patients Undergoing Strabismus Surgery: A Randomized Clinical Trial
CONCLUSION: The injection of atropine can effectively reduce the incidence of OCR during strabismus surgery and reduce its severity if this reflex occurs.PMID:38525386 | PMC:PMC10958729 | DOI:10.4103/abr.abr_167_23 (Source: Biomed Res)
Source: Biomed Res - March 25, 2024 Category: Research Authors: Darioush Moradi Farsani Seyed Ehsan Shakerinia Source Type: research
Effectiveness of Group Emotional Schema Therapy on Psychological Distress, Severity and Frequency of Symptoms in Women with Irritable Bowel Syndrome
CONCLUSION: Emotional schema therapy can be used as a complementary psychological treatment to reduce psychological distress and severity and frequency of symptoms in women with IBS.PMID:38525387 | PMC:PMC10958722 | DOI:10.4103/abr.abr_85_22 (Source: Biomed Res)
Source: Biomed Res - March 25, 2024 Category: Research Authors: Arefeh Erfan Asghar Aghaei Mohsen Golparvar Source Type: research
CTNS Mutations Causing Autosomal Recessive Cystinosis in a Subset of Iranian Population: Report of Two New Variants
CONCLUSION: The mutational spectrum in the Iranian patients is the same as previously reported mutations except that two new mutations were found. The present findings will present suggestions for regular molecular diagnosis of cystinosis in Iran.PMID:38525388 | PMC:PMC10958734 | DOI:10.4103/abr.abr_149_23 (Source: Biomed Res)
Source: Biomed Res - March 25, 2024 Category: Research Authors: Zahra Mohammadi Chermahini Mansoor Salehi Alaleh Gheissari Faeze Ahmadi Beni Farinaz Khosravian Mohammad Kazemi Source Type: research
A Comparison of the Clinical Outcomes of Minimum and Maximum Hematocrit Levels During Cardiopulmonary Bypass (CPB) in Low-risk Patients Undergoing Coronary Artery Bypass Graft Surgery (CABG): A Cross-sectional Study
CONCLUSION: According to the results of this study, patients undergoing CABG surgery with maximum HCT level versus minimum HCT level during CPB, need more packed cells and fresh frozen plasma products transfusion, which will be associated with the complication of cognitive impairment.PMID:38525389 | PMC:PMC10958727 | DOI:10.4103/abr.abr_145_23 (Source: Biomed Res)
Source: Biomed Res - March 25, 2024 Category: Research Authors: Fatemeh Shiravi Mehran Shahzamani Sayyed Alireza Hosseini Davood Shafie Source Type: research
Investigating the Effect of Aspirin on apoAI-Induced ATP Binding Cassette Transporter 1 Protein Expression and Cholesterol Efflux in Human Astrocytes
CONCLUSIONS: The results suggest a potential role of aspirin in increasing ABCA1 expression and cholesterol efflux in astrocytes, similar to the effect of apoA-I. This indicates that aspirin could potentially regulate brain cholesterol balance and can be considered in certain neurological diseases, in particular in some neurological disorders related to cholesterol accumulation such as Alzheimer's disease.PMID:38525390 | PMC:PMC10958728 | DOI:10.4103/abr.abr_417_22 (Source: Biomed Res)
Source: Biomed Res - March 25, 2024 Category: Research Authors: Zahra Nazeri Neda Abdeveiszadeh Vahid Zarezade Shirin Azizidoost Maryam Cheraghzadeh Mohammad Aberumand Alireza Kheirollah Source Type: research
A Randomized Comparative Study of the Use of Individual Modality and Combination of Endoscopic Retrograde Cholangiopancreatography (ERCP) and Digital Single-Operator Cholangioscopy (DSOC) for Diagnosis of Indeterminate Biliary Strictures
CONCLUSION: To conclude, the combination of ERCP with DSOC is safe and effective with higher diagnostic sensitivity (77.27%) in comparison to standard ERCP or DSOC alone (44.4%) for the diagnosis of biliary strictures.PMID:38525391 | PMC:PMC10958731 | DOI:10.4103/abr.abr_220_23 (Source: Biomed Res)
Source: Biomed Res - March 25, 2024 Category: Research Authors: Dheeraj Kumar Vishwa M Dayal Sanjeev K Jha Ashish K Jha Ravi K Kumar Source Type: research
The Efficacy of Repetitive Transcranial Magnetic Stimulation (rTMS) versus Transcranial Direct-Current Stimulation (tDCS) on Migraine Headaches: A Randomized Clinical Trial
CONCLUSION: Our findings suggest that both rTMS and tDCS may be effective in reducing pain intensity and improving the impact of headaches on daily life and anxiety in patients with chronic migraine. However, significant improvement in depression was only observed in the rTMS group patients.PMID:38525392 | PMC:PMC10958735 | DOI:10.4103/abr.abr_142_23 (Source: Biomed Res)
Source: Biomed Res - March 25, 2024 Category: Research Authors: Fatemeh Naji Mohammad Reza Sharbafchi Fariborz Khorvash Mohammad R Maracy Niloofar Ghasemi Mobarak Abadi Source Type: research
Comparative Evaluation of Direct Laryngoscopy Versus GlideScope for the Purpose of Laryngoscopy Management and Intubation in Candidates of Cesarean Delivery with General Anesthesia
CONCLUSION: It seems that the GSL technique is a better choice to conduct laryngoscopy with more success in intubation and a higher stability of the patients' hemodynamic status.PMID:38525393 | PMC:PMC10958721 | DOI:10.4103/abr.abr_308_21 (Source: Biomed Res)
Source: Biomed Res - March 25, 2024 Category: Research Authors: Azim Honarmand Mahtab Ebrahim Babaei Mohammad Jafari Mohammad Reza Safavi Source Type: research
The effectiveness of neurodynamic techniques in patients with diabetic peripheral neuropathy: Study protocol for a randomized sham-controlled trial
CONCLUSIONS: The present study will evaluate the efficacy of NDT on the primary and secondary outcome measurements in DPN patients.PMID:38525394 | PMC:PMC10958726 | DOI:10.4103/abr.abr_180_23 (Source: Biomed Res)
Source: Biomed Res - March 25, 2024 Category: Research Authors: Mahdi Ashoori Mohammadreza Pourahmadi Seyed Ebrahim Hashemi Mehdi Dadgoo Mahboobeh Sadat Hosseini Source Type: research
The Effect of Rivaroxaban in the Complementary Therapy of Sudden Sensorineural Hearing Loss
CONCLUSION: According to the results of this study, although the percentage of hearing recovery was higher in the RXA group, in general, the results of the two treatments were not significantly different.PMID:38525395 | PMC:PMC10958720 | DOI:10.4103/abr.abr_143_23 (Source: Biomed Res)
Source: Biomed Res - March 25, 2024 Category: Research Authors: Mehrdad Rogha Ehsan Moshtaghi Source Type: research
Therapeutic Effects of Tretinoin and Caffeine-Treated Bone Marrow-Derived Mesenchymal Stem Cell on Immunological Features of Ulcerative Colitis: An Animal Model Study
CONCLUSION: MSC therapy is an effective option for UC and can prevent disease progression. The results represented a high developmental rate and simple cell application of MSC therapy in UC patients. Also, MSC therapy's ability for immunomodulation is strengthened by drugs that improve their microenvironment by binding to their receptors.PMID:38525396 | PMC:PMC10958723 | DOI:10.4103/abr.abr_173_23 (Source: Biomed Res)
Source: Biomed Res - March 25, 2024 Category: Research Authors: Behnaz Movaffaghbani Hadi Esmaeili Gouvarchinghaleh Mahdieh Farzanehpour Jalal Shayegh Source Type: research
The Effect of Dextrose Hypotonic vs Saline Hydration on Methotrexate-Induced Nephrotoxicity in Male and Female Rats
CONCLUSION: Based on the findings of this study, hydration with N/S was superior to DW5% for the prevention from HDMTX-induced nephrotoxicity. Besides, we found insignificant differences between male versus female rats in response to the hydration for HDMTX-induced renoprotection; however, females probably benefit more.PMID:38525397 | PMC:PMC10958733 | DOI:10.4103/abr.abr_269_22 (Source: Biomed Res)
Source: Biomed Res - March 25, 2024 Category: Research Authors: Zahra Hasanpour Samira Choopani Farzaneh Ashrafi Ardeshir Talebi Mehdi Nematbaksh Source Type: research
The Application of Artificial Intelligence and Drug Repositioning for the Identification of Fibroblast Growth Factor Receptor Inhibitors: A Review
Adv Biomed Res. 2024 Jan 30;13:9. doi: 10.4103/abr.abr_170_23. eCollection 2024.ABSTRACTArtificial intelligence talks about modeling intelligent behavior through a computer with the least human involvement. Drug repositioning techniques based on artificial intelligence accelerate the research process and decrease the cost of experimental studies. Dysregulation of fibroblast growth factor (FGF) receptors as the tyrosine kinase family of receptors plays a vital role in a wide range of malignancies. Because of their functional significance, they were considered promising drug targets for the therapy of various cancers. This r...
Source: Biomed Res - March 25, 2024 Category: Research Authors: Parvin Zarei Fahimeh Ghasemi Source Type: research
Quality of Life in Patients with Phenylketonuria: A Systematic Review
This article reviews current researches on the impact of PKU on QoL. The review examines factors that may influence QoL, such as age, metabolic control, and treatment adherence. In this systematic review study, relevant articles were identified using a search strategy built with the keywords phenylketonuria, PKU, or hyperphenylalaninemia (or their synonyms) and QoL in Web of Science, Scopus, and PubMed databases. After identifying the articles, duplicates, reviews, scientific abstracts, articles published in languages other than English, and non relevant studies were excluded. The search strategy identified 951 records fro...
Source: Biomed Res - March 25, 2024 Category: Research Authors: Zahra Jahangiri Noushin Rostampour Silva Hovsepian Rojin Chegini Mahin Hashemipour Source Type: research
