Effect of radiation cross-linked collagen scaffold in alveolar ridge preservation of extraction socket
This study aimed to evaluate the properties of radiation cross-linked collagen scaffold (RCS) and its efficacy for alveolar ridge preservation (ARP). RCS was prepared from collagen dispersion by electron beam irradiation and freeze-drying. The microstructure, swelling ratio, area alteration and mechanical properties of RCS were characterized. Fifty-four New Zealand rabbits performing incisor extraction on maxilla and mandible were randomly assigned into positive, sham operation or treatment groups. Micro-computed tomography (micro-CT) scans, performed after 1, 4, and 12 weeks of surgery, were to assess changes in ridge hei...
Source: Biomed Res - April 12, 2024 Category: Research Authors: Hongwei Li Chen Yang Gong Chen Bozhao Wang Jian Li Ling Xu Source Type: research
Identification of Novel Molecular and Clinical Biomarkers of Survival in Glioblastoma Multiforme Patients: A Study Based on The Cancer Genome Atlas Data
This study is aimed at investigating the genetic alterations and clinical features of GBM patients to find predictors of survival. GBM patients' methylation and gene expression data along with clinical information from TCGA were retrieved. The most overrepresented pathways were identified independently for each omics dataset. From the genes found in at least 30% of these pathways, one gene that was identified in both sets was further examined using the Kaplan-Meier method for survival analysis. Additionally, three groups of patients who started radio and chemotherapy at different times were identified, and the influence of...
Source: Biomed Res - April 12, 2024 Category: Research Authors: Lu ísa Esteves Francisco Caramelo Domingos Roda Isabel Marques Carreira Joana Barbosa Melo Ilda Patr ícia Ribeiro Source Type: research
Bonding Effectiveness of Saliva-Contaminated Monolithic Zirconia Ceramics Using Different Decontamination Protocols
CONCLUSIONS: Universal cleaning agents can be preferred as an efficient cleaning method with 10-MDP-containing cement after saliva contamination for better adhesive bond strength of 4 mm crown preparation height of monolithic zirconia ceramics.PMID:38606199 | PMC:PMC11008971 | DOI:10.1155/2024/6670159 (Source: Biomed Res)
Source: Biomed Res - April 12, 2024 Category: Research Authors: Necla Demir Ozge Genc Ipek Balevi Akkese Meral Arslan Malkoc Mutlu Ozcan Source Type: research
Effect of radiation cross-linked collagen scaffold in alveolar ridge preservation of extraction socket
This study aimed to evaluate the properties of radiation cross-linked collagen scaffold (RCS) and its efficacy for alveolar ridge preservation (ARP). RCS was prepared from collagen dispersion by electron beam irradiation and freeze-drying. The microstructure, swelling ratio, area alteration and mechanical properties of RCS were characterized. Fifty-four New Zealand rabbits performing incisor extraction on maxilla and mandible were randomly assigned into positive, sham operation or treatment groups. Micro-computed tomography (micro-CT) scans, performed after 1, 4, and 12 weeks of surgery, were to assess changes in ridge hei...
Source: Biomed Res - April 12, 2024 Category: Research Authors: Hongwei Li Chen Yang Gong Chen Bozhao Wang Jian Li Ling Xu Source Type: research
Identification of Novel Molecular and Clinical Biomarkers of Survival in Glioblastoma Multiforme Patients: A Study Based on The Cancer Genome Atlas Data
This study is aimed at investigating the genetic alterations and clinical features of GBM patients to find predictors of survival. GBM patients' methylation and gene expression data along with clinical information from TCGA were retrieved. The most overrepresented pathways were identified independently for each omics dataset. From the genes found in at least 30% of these pathways, one gene that was identified in both sets was further examined using the Kaplan-Meier method for survival analysis. Additionally, three groups of patients who started radio and chemotherapy at different times were identified, and the influence of...
Source: Biomed Res - April 12, 2024 Category: Research Authors: Lu ísa Esteves Francisco Caramelo Domingos Roda Isabel Marques Carreira Joana Barbosa Melo Ilda Patr ícia Ribeiro Source Type: research
Bonding Effectiveness of Saliva-Contaminated Monolithic Zirconia Ceramics Using Different Decontamination Protocols
CONCLUSIONS: Universal cleaning agents can be preferred as an efficient cleaning method with 10-MDP-containing cement after saliva contamination for better adhesive bond strength of 4 mm crown preparation height of monolithic zirconia ceramics.PMID:38606199 | PMC:PMC11008971 | DOI:10.1155/2024/6670159 (Source: Biomed Res)
Source: Biomed Res - April 12, 2024 Category: Research Authors: Necla Demir Ozge Genc Ipek Balevi Akkese Meral Arslan Malkoc Mutlu Ozcan Source Type: research
Effect of radiation cross-linked collagen scaffold in alveolar ridge preservation of extraction socket
This study aimed to evaluate the properties of radiation cross-linked collagen scaffold (RCS) and its efficacy for alveolar ridge preservation (ARP). RCS was prepared from collagen dispersion by electron beam irradiation and freeze-drying. The microstructure, swelling ratio, area alteration and mechanical properties of RCS were characterized. Fifty-four New Zealand rabbits performing incisor extraction on maxilla and mandible were randomly assigned into positive, sham operation or treatment groups. Micro-computed tomography (micro-CT) scans, performed after 1, 4, and 12 weeks of surgery, were to assess changes in ridge hei...
Source: Biomed Res - April 12, 2024 Category: Research Authors: Hongwei Li Chen Yang Gong Chen Bozhao Wang Jian Li Ling Xu Source Type: research
Synthetic strategy for the production of electrically polarized polyvinylidene fluoride-trifluoroethylene-co-polymer osseo-functionalized with hydroxyapatite scaffold
J Biomed Mater Res A. 2024 Apr 10. doi: 10.1002/jbm.a.37720. Online ahead of print.ABSTRACTThe physiological mechanism of bone tissue regeneration is intricately organized and involves several cell types, intracellular, and extracellular molecular signaling networks. To overcome the drawbacks of autografts and allografts, a number of synthetically produced scaffolds have been manufactured by integrating ceramics, polymers, and their hybrid-composites. Considering the fact that natural bone is composed primarily of collagen and hydroxyapatite, ceramic-polymer composite materials seem to be the most viable alternative to bon...
Source: Biomed Res - April 11, 2024 Category: Research Authors: Subhasmita Swain Rojaleen Lenka Tapash Rautray Source Type: research
Gut and Vaginal Microbiota in the Endometriosis: Systematic Review and Meta-Analysis
CONCLUSION: In intestinal and vaginal samples from women with endometriosis, alpha-diversity did not present a significant difference when compared to the control population. However, each study individually showed a possible relationship between the female microbiota and endometriosis. This trial is registered with CRD42021260972.PMID:38601772 | PMC:PMC11006450 | DOI:10.1155/2023/2675966 (Source: Biomed Res)
Source: Biomed Res - April 11, 2024 Category: Research Authors: Tamy Colonetti Maria Carolina Saggioratto Antonio Jos é Grande Laura Colonetti Jo ão Carlos Denoni Junior Luciane Bisognin Ceretta Leonardo Roever F ábio Rosa Silva Maria In ês da Rosa Source Type: research
In vivo effects of cell seeding technique in an ex vivo regional gene therapy model for bone regeneration
This study investigated if human adipose-derived stem cells (ASCs) transduced with a lentiviral vector to overexpress bone morphogenetic protein 2 (BMP-2) and loaded on a scaffold using dynamic orbital shaker could reduce the total cell dose required to heal a critical sized bone defect when compared with static seeding. Human ASCs were loaded onto a collagen/biphasic ceramic scaffold using static loading and dynamic orbital shaker techniques, compared with our labs standard loading technique, and implanted into femoral defects of nude rats. Both a low dose and standard dose of transduced cells were evaluated. Outcomes inv...
Source: Biomed Res - April 11, 2024 Category: Research Authors: Jennifer A Bell Cory K Mayfield Kevin Collon Stephanie Chang Matthew C Gallo Elizabeth Lechtholz-Zey Mina Ayad Osamu Sugiyam Amy H Tang Sang-Hyun Park Jay R Lieberman Source Type: research
Synthetic strategy for the production of electrically polarized polyvinylidene fluoride-trifluoroethylene-co-polymer osseo-functionalized with hydroxyapatite scaffold
J Biomed Mater Res A. 2024 Apr 10. doi: 10.1002/jbm.a.37720. Online ahead of print.ABSTRACTThe physiological mechanism of bone tissue regeneration is intricately organized and involves several cell types, intracellular, and extracellular molecular signaling networks. To overcome the drawbacks of autografts and allografts, a number of synthetically produced scaffolds have been manufactured by integrating ceramics, polymers, and their hybrid-composites. Considering the fact that natural bone is composed primarily of collagen and hydroxyapatite, ceramic-polymer composite materials seem to be the most viable alternative to bon...
Source: Biomed Res - April 11, 2024 Category: Research Authors: Subhasmita Swain Rojaleen Lenka Tapash Rautray Source Type: research
Gut and Vaginal Microbiota in the Endometriosis: Systematic Review and Meta-Analysis
CONCLUSION: In intestinal and vaginal samples from women with endometriosis, alpha-diversity did not present a significant difference when compared to the control population. However, each study individually showed a possible relationship between the female microbiota and endometriosis. This trial is registered with CRD42021260972.PMID:38601772 | PMC:PMC11006450 | DOI:10.1155/2023/2675966 (Source: Biomed Res)
Source: Biomed Res - April 11, 2024 Category: Research Authors: Tamy Colonetti Maria Carolina Saggioratto Antonio Jos é Grande Laura Colonetti Jo ão Carlos Denoni Junior Luciane Bisognin Ceretta Leonardo Roever F ábio Rosa Silva Maria In ês da Rosa Source Type: research
First Molecular Detection of SARS-CoV-2 in Sewage and Wastewater in Ghana
This study is aimed at detecting the virus and its potential survival in sewage and wastewater in Ghana. The cross-sectional study included samples from 16 validated environmental surveillance sites in 7 regions of Ghana. A total of 354 samples composed of wastewater (280) and sewage (74) were collected from November 2020 to November 2022. Overall, 17% of the samples were positive for SARS-CoV-2 by real-time PCR, with 6% in sewage and 11% in wastewater. The highest number of positive samples was collected from the Greater Accra Region (7.3%) with the least recorded in the Bono East Region (0.6%). Further characterization o...
Source: Biomed Res - April 10, 2024 Category: Research Authors: Ewurabena Oduma Duker Evangeline Obodai Seth Offei Addo Lorreta Kwasah Edna Serwah Mensah Emmanuel Gberbi Abraham Anane Keren O Attiku Jessica Boakye Gayheart Deladem Agbotse Angelina Evelyn Dickson Joseph Ahia Quarcoo Patience Akosua Darko Yaw Awuku Larb Source Type: research
Genome-Wide Investigation Reveals Potential Therapeutic Targets in < em > Shigella < /em > spp
In this study, 2,146 ARGs were predicted in 45 genomes (average 47.69 ARGs/genome), of which only 91 ARGs were found to be shared across the genomes. Majority of these ARGs conferred their resistance through antibiotic efflux pump (51.0%) followed by antibiotic target alteration (23%) and antibiotic target replacement (18%). We identified 13 hub proteins, of which four proteins (e.g., tolC, acrR, mdtA, and gyrA) were detected as potential hub proteins to be associated with antibiotic efflux pump and target alteration mechanisms. These hub proteins were significantly (p < 0.05) enriched in biological process, molecular f...
Source: Biomed Res - April 10, 2024 Category: Research Authors: Md Arju Hossain Md Al Amin Md Arif Khan Md Rashedur Rahman Refat Md Sohel Md Habibur Rahman Ariful Islam M Nazmul Hoque Source Type: research
Understanding Challenges Women Face in Flood-Affected Areas to Access Sexual and Reproductive Health Services: A Rapid Assessment from a Disaster-Torn Pakistan
CONCLUSION: The findings concluded that there was no planning for sexual and reproductive health services in the flood-affected areas. Several barriers were identified. The government and development partners needed to prepare to cater to women's needs during the floods. The findings highlight the need for collaborative efforts between the government, civil society, and development partners to address the challenges faced in disaster management and strengthen disaster management capacity.PMID:38590384 | PMC:PMC11001467 | DOI:10.1155/2024/1113634 (Source: Biomed Res)
Source: Biomed Res - April 9, 2024 Category: Research Authors: Mariam Ashraf Sara Shahzad Pamela Sequeria Anam Bashir Syed Khurram Azmat Source Type: research
