Assessment of the anti-inflammatory and biological properties of Bioroot Flow: A novel bioceramic sealer
CONCLUSIONS: Taken together, these findings indicate that BRF can potentially enhance cell differentiation by promoting the expression of essential genes related to bone and cement formation. In addition, BRF and TFbc displayed anti-inflammatory effects.PMID:38657320 | DOI:10.1016/j.tice.2024.102391 (Source: Tissue and Cell)
Source: Tissue and Cell - April 24, 2024 Category: Cytology Authors: Sergio L ópez-García Jos é L Sanz Laura Murcia David Garc ía-Bernal Adri án Lozano Leopoldo Forner Francisco J Rodr íguez-Lozano Ricardo E O ñate-Sánchez Source Type: research
AMPK/autophagy-mediated alleviation of tendinopathy by IL-38: A novel strategy for the treatment of obesity-related tendinopathy
This study provides a promising therapeutic avenue for treating obesity-related tendinopathy using an endogenous compound such as IL-38.PMID:38643674 | DOI:10.1016/j.tice.2024.102392 (Source: Tissue and Cell)
Source: Tissue and Cell - April 21, 2024 Category: Cytology Authors: Sung Su Park Wonjun Cho Do Su Lim Hyeon Ji Gwon Sung Woo Choi A M Abd El-Aty Hac ı Ahmet Aydemir Ji Hoon Jeong Tae Woo Jung Source Type: research
AMPK/autophagy-mediated alleviation of tendinopathy by IL-38: A novel strategy for the treatment of obesity-related tendinopathy
This study provides a promising therapeutic avenue for treating obesity-related tendinopathy using an endogenous compound such as IL-38.PMID:38643674 | DOI:10.1016/j.tice.2024.102392 (Source: Tissue and Cell)
Source: Tissue and Cell - April 21, 2024 Category: Cytology Authors: Sung Su Park Wonjun Cho Do Su Lim Hyeon Ji Gwon Sung Woo Choi A M Abd El-Aty Hac ı Ahmet Aydemir Ji Hoon Jeong Tae Woo Jung Source Type: research
Lingual adaptations of the Tarentola annularis with new insights into its papillary system adaptations: Ultrastructure, histochemistry, and immunohistochemical observations
Tissue Cell. 2024 Apr 6;88:102366. doi: 10.1016/j.tice.2024.102366. Online ahead of print.ABSTRACTOur research aims to conduct a comprehensive ultrastructural, histochemical, and immunohistochemical examination of Tarentola annularis' tongue, utilizing various techniques such as light, scanning electron microscopy, and morphometric analysis. The complex papillary system consisted of four conical subtypes and one filiform type. The apex carried three conical subtypes (elongated, quadrilateral, and round); the midtongue carried two papillary types (quadrilateral conical and rectangular pointed filiform); and the hindtongue c...
Source: Tissue and Cell - April 19, 2024 Category: Cytology Authors: Ramadan M Kandyel Hebat Allah El Basyouny Sahar El-Nagar Naglaa Madkour Diaa Massoud Abdulrhman A Almadiy Bader Albogami Saeed Alasmari Mohamed Abumandour Source Type: research
A novel cell-free therapy using exosomes in the inner ear regeneration
Tissue Cell. 2024 Apr 9;88:102373. doi: 10.1016/j.tice.2024.102373. Online ahead of print.ABSTRACTCellular and molecular alterations associated with hearing loss are now better understood with advances in molecular biology. These changes indicate the participation of distinct damage and stress pathways that are unlikely to be fully addressed by conventional pharmaceutical treatment. Sensorineural hearing loss is a common and debilitating condition for which comprehensive pharmacologic intervention is not available. The complex and diverse molecular pathology that underlies hearing loss currently limits our ability to inter...
Source: Tissue and Cell - April 19, 2024 Category: Cytology Authors: Masoumeh Amiri Mohammad Amin Kaviari Gelavizh Rostaminasab Amir Barimani Leila Rezakhani Source Type: research
TBBPS caused necroptosis and inflammation in hepatocytes by blocking PINK1-PARKIN-mediated mitochondrial autophagy
Tissue Cell. 2024 Apr 10;88:102382. doi: 10.1016/j.tice.2024.102382. Online ahead of print.ABSTRACTThe widespread use of Tetrabromobisphenol S (TBBPS), as an alternative to tetrabromobisphenol A (TBBPA), has been detected at high frequency in environmental media in recent years, TBBPS can enter the body via the digestive tract and other routes, thus long-term TBBPS exposure may cause adverse health effects. Therefore, it is necessary to evaluate the toxicological effects of TBBPS. In the current work, two cell models of the liver were used (a human-derived cell line THLE-2 and a murine-derived AML12). The liver cells were ...
Source: Tissue and Cell - April 18, 2024 Category: Cytology Authors: Yujun Yin Minshi Huang Jianlong Xie Yongfang Ou Tianfu Mai Source Type: research
P300 reduces TUBB4B expression to facilitate the biological process of migration and invasion of non-small cell lung cancer cells
This article explored the mechanism of E1A binding protein p300 (P300) and beta-tubulin 4B isotype-encoding gene (TUBB4B) in regulating the migration and invasion of non-small cell lung cancer (NSCLC) cells. TUBB4B and P300 expression in NSCLC tissues and cells was monitored by real-time quantitative reverse transcription-polymerase chain reaction (qRT-PCR) and Western blot. TUBB4B function on NSCLC cell migration, invasion and epithelial-mesenchymal transition (EMT) was monitored by wound healing assay, Transwell experiment and Western blot. The regulation of P300 on TUBB4B was monitored by qRT-PCR and Western blot. Mecha...
Source: Tissue and Cell - April 18, 2024 Category: Cytology Authors: Haifeng Hu Yun Zhang Haibo Zhai Juanjuan Dong Lei Zuo Xiaolei Guo Chao Wang Source Type: research
TBBPS caused necroptosis and inflammation in hepatocytes by blocking PINK1-PARKIN-mediated mitochondrial autophagy
Tissue Cell. 2024 Apr 10;88:102382. doi: 10.1016/j.tice.2024.102382. Online ahead of print.ABSTRACTThe widespread use of Tetrabromobisphenol S (TBBPS), as an alternative to tetrabromobisphenol A (TBBPA), has been detected at high frequency in environmental media in recent years, TBBPS can enter the body via the digestive tract and other routes, thus long-term TBBPS exposure may cause adverse health effects. Therefore, it is necessary to evaluate the toxicological effects of TBBPS. In the current work, two cell models of the liver were used (a human-derived cell line THLE-2 and a murine-derived AML12). The liver cells were ...
Source: Tissue and Cell - April 18, 2024 Category: Cytology Authors: Yujun Yin Minshi Huang Jianlong Xie Yongfang Ou Tianfu Mai Source Type: research
P300 reduces TUBB4B expression to facilitate the biological process of migration and invasion of non-small cell lung cancer cells
This article explored the mechanism of E1A binding protein p300 (P300) and beta-tubulin 4B isotype-encoding gene (TUBB4B) in regulating the migration and invasion of non-small cell lung cancer (NSCLC) cells. TUBB4B and P300 expression in NSCLC tissues and cells was monitored by real-time quantitative reverse transcription-polymerase chain reaction (qRT-PCR) and Western blot. TUBB4B function on NSCLC cell migration, invasion and epithelial-mesenchymal transition (EMT) was monitored by wound healing assay, Transwell experiment and Western blot. The regulation of P300 on TUBB4B was monitored by qRT-PCR and Western blot. Mecha...
Source: Tissue and Cell - April 18, 2024 Category: Cytology Authors: Haifeng Hu Yun Zhang Haibo Zhai Juanjuan Dong Lei Zuo Xiaolei Guo Chao Wang Source Type: research
Autophagy enhances the differentiation of insulin-producing cells from Wharton's jelly-derived mesenchymal stem cells
Tissue Cell. 2024 Apr 15;88:102384. doi: 10.1016/j.tice.2024.102384. Online ahead of print.ABSTRACTAutophagy disruption suppresses insulin production and induces diabetes. The role of autophagy in the differentiation of Wharton's jelly (WJ)-derived mesenchymal stem cells (WJSCs) into insulin-producing cells (IPCs) was investigated in this experimental study. The WJSCs were incubated in a differentiation medium (DM) with or without an autophagy inhibitor (3-methyladenine: 3MA). The differentiation of IPCs was confirmed by flow cytometry analysis of PDX-1 and insulin-positive cells, insulin secretion, and the high expression...
Source: Tissue and Cell - April 16, 2024 Category: Cytology Authors: Nastaran Azarbarz Fereshteh Nejaddehbashi Layasadat Khorsandi Dariuosh Bijan Nejad Ali Sayyahi Source Type: research
Molecular mechanisms underlying cisplatin-induced nephrotoxicity and the potential ameliorative effects of essential oils: A comprehensive review
Tissue Cell. 2024 Apr 6;88:102377. doi: 10.1016/j.tice.2024.102377. Online ahead of print.ABSTRACTSince the Middle Ages, essential oils (EO) have been widely used for bactericidal, virucidal, fungicidal, insecticidal, medicinal and cosmetic applications, nowadays in pharmaceutical, agricultural and food industries. Recently, EO have emerged as promising adjuvant therapies to mitigate the toxicities induced by anti - cancerous drugs; among them cisplatin induced renal damage amelioration remain remarkable. Cisplatin (cis-diaminedichloroplatinum II, CDDP) is renowned as one of the most effective anti-neoplastic agents, widel...
Source: Tissue and Cell - April 16, 2024 Category: Cytology Authors: Saraswati Patel V Sathyanathan Samsi D Salaman Source Type: research
Autophagy enhances the differentiation of insulin-producing cells from Wharton's jelly-derived mesenchymal stem cells
Tissue Cell. 2024 Apr 15;88:102384. doi: 10.1016/j.tice.2024.102384. Online ahead of print.ABSTRACTAutophagy disruption suppresses insulin production and induces diabetes. The role of autophagy in the differentiation of Wharton's jelly (WJ)-derived mesenchymal stem cells (WJSCs) into insulin-producing cells (IPCs) was investigated in this experimental study. The WJSCs were incubated in a differentiation medium (DM) with or without an autophagy inhibitor (3-methyladenine: 3MA). The differentiation of IPCs was confirmed by flow cytometry analysis of PDX-1 and insulin-positive cells, insulin secretion, and the high expression...
Source: Tissue and Cell - April 16, 2024 Category: Cytology Authors: Nastaran Azarbarz Fereshteh Nejaddehbashi Layasadat Khorsandi Dariuosh Bijan Nejad Ali Sayyahi Source Type: research
Molecular mechanisms underlying cisplatin-induced nephrotoxicity and the potential ameliorative effects of essential oils: A comprehensive review
Tissue Cell. 2024 Apr 6;88:102377. doi: 10.1016/j.tice.2024.102377. Online ahead of print.ABSTRACTSince the Middle Ages, essential oils (EO) have been widely used for bactericidal, virucidal, fungicidal, insecticidal, medicinal and cosmetic applications, nowadays in pharmaceutical, agricultural and food industries. Recently, EO have emerged as promising adjuvant therapies to mitigate the toxicities induced by anti - cancerous drugs; among them cisplatin induced renal damage amelioration remain remarkable. Cisplatin (cis-diaminedichloroplatinum II, CDDP) is renowned as one of the most effective anti-neoplastic agents, widel...
Source: Tissue and Cell - April 16, 2024 Category: Cytology Authors: Saraswati Patel V Sathyanathan Samsi D Salaman Source Type: research
Mesenchymal stem cells for cartilage regeneration: Insights into molecular mechanism and therapeutic strategies
In conclusion, this paper provides a comprehensive overview of the molecular mechanisms involved in MSC-based cartilage regeneration and outlines promising therapeutic strategies. The insights presented contribute to the ongoing efforts in optimizing MSC-based therapies for effective cartilage repair.PMID:38615643 | DOI:10.1016/j.tice.2024.102380 (Source: Tissue and Cell)
Source: Tissue and Cell - April 14, 2024 Category: Cytology Authors: Merlin Mamachan Khan Sharun S Amitha Banu Sathish Muthu Abhijit M Pawde Laith Abualigah Swapan Kumar Maiti Source Type: research
Mesenchymal stem cells for cartilage regeneration: Insights into molecular mechanism and therapeutic strategies
In conclusion, this paper provides a comprehensive overview of the molecular mechanisms involved in MSC-based cartilage regeneration and outlines promising therapeutic strategies. The insights presented contribute to the ongoing efforts in optimizing MSC-based therapies for effective cartilage repair.PMID:38615643 | DOI:10.1016/j.tice.2024.102380 (Source: Tissue and Cell)
Source: Tissue and Cell - April 14, 2024 Category: Cytology Authors: Merlin Mamachan Khan Sharun S Amitha Banu Sathish Muthu Abhijit M Pawde Laith Abualigah Swapan Kumar Maiti Source Type: research
