Hypoxia preconditioning of human amniotic mesenchymal stem cells enhances proliferation and migration and promotes their homing via the HGF/C-MET signaling axis to augment the repair of acute liver failure
CONCLUSIONS: Hypoxic preconditioning depicted no impact on the morphology and phenotype features of the human amniotic mesenchymal stem cells, but it can promote their proliferation, migration, anti-apoptotic effect, and homing rate and improve the repair of acute liver failure, which might be mediated by the HGF/c-Met signaling axis.PMID:38442547 | DOI:10.1016/j.tice.2024.102326 (Source: Tissue and Cell)
Source: Tissue and Cell - March 5, 2024 Category: Cytology Authors: Qian Wang Yuwen Li Hui Yuan Linya Peng Zixing Dai Ye Sun Rui Liu Wenting Li Jun Li Chuanlong Zhu Source Type: research
Microfluidics devices for sports: A review on technology for biomedical application used in fields such as biomedicine, drug encapsulation, preparation of nanoparticles, cell targeting, analysis, diagnosis, and cell culture
In conclusion, this review emphasizes the potential of microfluidic technology and highlights the need for continued research to fully exploit its potential in the biomedical field and sport applications.PMID:38432127 | DOI:10.1016/j.tice.2024.102339 (Source: Tissue and Cell)
Source: Tissue and Cell - March 3, 2024 Category: Cytology Authors: Xuehui Lei Weiwu Ye F Safdarin Sh Baghaei Source Type: research
Microfluidics devices for sports: A review on technology for biomedical application used in fields such as biomedicine, drug encapsulation, preparation of nanoparticles, cell targeting, analysis, diagnosis, and cell culture
In conclusion, this review emphasizes the potential of microfluidic technology and highlights the need for continued research to fully exploit its potential in the biomedical field and sport applications.PMID:38432127 | DOI:10.1016/j.tice.2024.102339 (Source: Tissue and Cell)
Source: Tissue and Cell - March 3, 2024 Category: Cytology Authors: Xuehui Lei Weiwu Ye F Safdarin Sh Baghaei Source Type: research
Ex vivo expansion of hematopoietic stem cells in two/ three-dimensional co-cultures with various source of stromal cells
Tissue Cell. 2024 Feb 19;87:102331. doi: 10.1016/j.tice.2024.102331. Online ahead of print.ABSTRACTThe ex vivo expansion of hematopoietic stem cells, with both high quantities and quality, is considered a paramount issue in cell and gene therapy for hematological diseases. Complex interactions between the bone marrow microenvironment and hematopoietic stem cells reveal the importance of using 2D and 3D coculture as a physiological system simulator in the proliferation, differentiation, and homeostasis of HSCs. Herein, the capacity of mesenchymal stem cells derived from different sources to support the expansion and mainten...
Source: Tissue and Cell - March 2, 2024 Category: Cytology Authors: Nasim Mayeli Fereydani Hamid Galehdari Elham Hoveizi Arash Alghasi Monireh Ajami Source Type: research
Impact of L-Arginine on diabetes-induced neuropathy and myopathy: Roles of PAI-1, Irisin, oxidative stress, NF- κβ, autophagy and microRNA-29a
CONCLUSIONS: ARG supplementation potently alleviated diabetic-induced neuromuscular alterations.PMID:38430848 | DOI:10.1016/j.tice.2024.102342 (Source: Tissue and Cell)
Source: Tissue and Cell - March 2, 2024 Category: Cytology Authors: Heba M Galal Alaa T Abdelhafez Manal M Sayed Walaa M S Gomaa Tohamy Anwar Tohamy Asmaa M S Gomaa Tarek H El-Metwally Source Type: research
Change and pathological significance of glycogen content in oral squamous cell carcinoma and oral submucous fibrosis
CONCLUSION: Glycogen may be used as a potential diagnostic biomolecule for OSF and OSCC, as well as a potential prognostic factor for OSCC in the context of OSF.PMID:38430849 | DOI:10.1016/j.tice.2024.102337 (Source: Tissue and Cell)
Source: Tissue and Cell - March 2, 2024 Category: Cytology Authors: Huanquan Nie Xin Hu Haofeng Xiong Liujun Zeng Wenxin Chen Tong Su Source Type: research
Overexpression of ETV2 in BMSCs promoted wound healing in cutaneous wound mice by triggering the differentiation of BMSCs into endothelial cells and modulating the transformation of M1 phenotype macrophages to M2 phenotype macrophages
In conclusion, this study revealed a novel biofunction of ETV2 molecule in the wound healing process. ETV2 overexpression in BMSCs promoted wound healing in CW mice by triggering BMSCs differentiation into endothelial cells and modulating the transformation of M1 pro-inflammatory and M2 anti-inflammatory macrophages in vitro and in vivo.PMID:38430850 | DOI:10.1016/j.tice.2024.102334 (Source: Tissue and Cell)
Source: Tissue and Cell - March 2, 2024 Category: Cytology Authors: Xiuchao Shang Yesheng Jin Yuan Xue Xiaoyun Pan Haiquan Zhu Xiangsheng Meng Zhihai Cao Yongjun Rui Source Type: research
The promising prospect of human hair follicle regeneration in the shadow of new tissue engineering strategies
Tissue Cell. 2024 Feb 28;87:102338. doi: 10.1016/j.tice.2024.102338. Online ahead of print.ABSTRACTHair loss disorder (alopecia) affects numerous people around the world. The low effectiveness and numerous side effects of common treatments have prompted researchers to investigate alternative and effective solutions. Hair follicle (HF) bioengineering is the knowledge of using hair-inductive (trichogenic) cells. Most bioengineering-based approaches focus on regenerating folliculogenesis through manipulation of regulators of physical/molecular properties in the HF niche. Despite the high potential of cell therapy, no cell pro...
Source: Tissue and Cell - March 1, 2024 Category: Cytology Authors: Arezoo Karami Vandishi Ali Esmaeili Niloofar Taghipour Source Type: research
The promising prospect of human hair follicle regeneration in the shadow of new tissue engineering strategies
Tissue Cell. 2024 Feb 28;87:102338. doi: 10.1016/j.tice.2024.102338. Online ahead of print.ABSTRACTHair loss disorder (alopecia) affects numerous people around the world. The low effectiveness and numerous side effects of common treatments have prompted researchers to investigate alternative and effective solutions. Hair follicle (HF) bioengineering is the knowledge of using hair-inductive (trichogenic) cells. Most bioengineering-based approaches focus on regenerating folliculogenesis through manipulation of regulators of physical/molecular properties in the HF niche. Despite the high potential of cell therapy, no cell pro...
Source: Tissue and Cell - March 1, 2024 Category: Cytology Authors: Arezoo Karami Vandishi Ali Esmaeili Niloofar Taghipour Source Type: research
Assessment of oxidative stress and tissue damage in Echinococcus granulosus naturally infected bovine liver
This study highlights the role of oxidative stress in the pathogenesis of Cystic Echinococcosis (CE) and the need for further investigation of antioxidant defense mechanisms and their regional variations.PMID:38422584 | DOI:10.1016/j.tice.2024.102333 (Source: Tissue and Cell)
Source: Tissue and Cell - February 29, 2024 Category: Cytology Authors: Tu ğçe Antepli Oğlu Tilbe Su Yapici Gungor Cagdas Dincel Ebtesam Al-Olayan Mohammad Y Alshahrani Saeed El-Ashram Source Type: research
Assessment of oxidative stress and tissue damage in Echinococcus granulosus naturally infected bovine liver
This study highlights the role of oxidative stress in the pathogenesis of Cystic Echinococcosis (CE) and the need for further investigation of antioxidant defense mechanisms and their regional variations.PMID:38422584 | DOI:10.1016/j.tice.2024.102333 (Source: Tissue and Cell)
Source: Tissue and Cell - February 29, 2024 Category: Cytology Authors: Tu ğçe Antepli Oğlu Tilbe Su Yapici Gungor Cagdas Dincel Ebtesam Al-Olayan Mohammad Y Alshahrani Saeed El-Ashram Source Type: research
Peiminine triggers ferroptosis to inhibit breast cancer growth through triggering Nrf2 signaling
CONCLUSION: Taking these finding together, PMI could stimulate ferroptosis to inhibit BC tumor growth by activating Nrf2-HO-1 signaling pathway.PMID:38412577 | DOI:10.1016/j.tice.2024.102323 (Source: Tissue and Cell)
Source: Tissue and Cell - February 27, 2024 Category: Cytology Authors: Nian Yi Li Wang Zhongjun Jiang Ge Xu Lihong Li Ya Zhang Yinna Tan Source Type: research
A comprehensive exploration of diverse skin cell types in the limb of the desert tortoise (Testudo graeca) through light, transmission, scanning electron microscopy, and immunofluorescence techniques
Tissue Cell. 2024 Feb 23;87:102335. doi: 10.1016/j.tice.2024.102335. Online ahead of print.ABSTRACTThe Greek tortoise, inhabiting harsh desert environments, provides a compelling case for investigating skin adaptations to extreme conditions. We have utilized light microscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), and immunofluorescence analysis to describe the structure of the arid-adapted limb skin in the Greek tortoise. Our aim was to identify the cell types that reflect the skin adaptation of this tortoise to arid conditions. Utilizing seven antibodies, we localized and elucidated t...
Source: Tissue and Cell - February 27, 2024 Category: Cytology Authors: Ahmed M Rashwan Samir A A El-Gendy Samar M Ez Elarab Mohamed A M Alsafy Source Type: research
Modulation of the Sirtuin-1 signaling pathway in doxorubicin-induced nephrotoxicity (synergistic amelioration by resveratrol and pirfenidone)
In conclusion, DOX exposure leads to renal toxicity by inducing renal degeneration, oxidative stress, and apoptosis. Administration of either resveratrol or Pirfenidone counteracted these changes and protected the kidney against DOX-induced renal damage.PMID:38412579 | DOI:10.1016/j.tice.2024.102330 (Source: Tissue and Cell)
Source: Tissue and Cell - February 27, 2024 Category: Cytology Authors: Samia Mahmoud Manawy Eman Mohamed Faruk Rabab Fawzy Hindawy Mahmoud M Hassan Diaa M G Farrag Mansour A E Bashar Hanan Fouad Rania Abubaker Bagabir Dina Allam Abdelmaksoud Hassan Ahmed Mohammed Zaazaa Mohamed Ghazy Attia Hablas K Mostafa Kamal Source Type: research
Peiminine triggers ferroptosis to inhibit breast cancer growth through triggering Nrf2 signaling
CONCLUSION: Taking these finding together, PMI could stimulate ferroptosis to inhibit BC tumor growth by activating Nrf2-HO-1 signaling pathway.PMID:38412577 | DOI:10.1016/j.tice.2024.102323 (Source: Tissue and Cell)
Source: Tissue and Cell - February 27, 2024 Category: Cytology Authors: Nian Yi Li Wang Zhongjun Jiang Ge Xu Lihong Li Ya Zhang Yinna Tan Source Type: research
