Alleviation of doxorubicin-induced cardiotoxicity in rat by mesenchymal stem cells and olive leaf extract via MAPK/ TNF- α pathway: Preclinical, experimental and bioinformatics enrichment study
CONCLUSION: Both OLE and BM-MSCs showed an ameliorating effect in rat models of DOX-induced cardiotoxicity, with BM-MSCs showing a greater influence than OLE.PMID:37865037 | DOI:10.1016/j.tice.2023.102239 (Source: Tissue and Cell)
Source: Tissue and Cell - October 21, 2023 Category: Cytology Authors: Mahrous A Ibrahim Athar M Khalifa Noha M Abd El-Fadeal Rehab I Abdel-Karim Ayman F Elsharawy Alia Ellawindy Heba M Galal Eman H Nadwa Mohamed A Abdel-Shafee Rania A Galhom Source Type: research
Apoptotic effects of mesenchymal stem cells' conditioned medium on colorectal cancer cell lines
In conclusion, the conditioned medium from LPS-preconditioned MSCs can effectively induce apoptosis in colorectal cancer cells. This finding suggests that LPS-CM could be a potential strategy for inhibiting the proliferation and progression of colorectal cancer cells.PMID:37865038 | DOI:10.1016/j.tice.2023.102247 (Source: Tissue and Cell)
Source: Tissue and Cell - October 21, 2023 Category: Cytology Authors: Roya Khamooshi Ali Salimi Raheleh Halabian Pardis Saeedi Source Type: research
TNF- α blockage by etanercept restores spatial learning and reduces cellular degeneration in the hippocampus during liver cirrhosis
In conclusion, TNF-α is strongly involved in the development of liver cirrhosis and the associated encephalopathy. TNF-α blockers may be a promising approach for management of hepatic cirrhosis and its cerebral complications.PMID:37865039 | DOI:10.1016/j.tice.2023.102249 (Source: Tissue and Cell)
Source: Tissue and Cell - October 21, 2023 Category: Cytology Authors: Rehab Nady Rasha R Ahmed Nadia Moustafa Manal Abdul-Hamid Source Type: research
Evaluating the protective role of trimetazidine versus nano-trimetazidine in amelioration of bilateral renal ischemia/reperfusion induced neuro-degeneration: Implications of ERK1/2, JNK and Galectin-3 /NF- κB/TNF-α/HMGB-1 signaling
CONCLUSION: Nano-TMZ is more than anti-ischemic.PMID:37865040 | DOI:10.1016/j.tice.2023.102241 (Source: Tissue and Cell)
Source: Tissue and Cell - October 21, 2023 Category: Cytology Authors: Fatma E Hassan Basma Emad Aboulhoda Isra H Ali Heba M Elwi Lamiaa M Matter Hend Ahmed Abdallah Mohamed Mansour Khalifa Asmaa Selmy Mansour A Alghamdi Suzan Awad Morsy Basant A Al Dreny Source Type: research
Mitochondrial transplantation inhibits cholangiocarcinoma cells growth by balancing oxidative stress tolerance through PTEN/PI3K/AKT signaling pathway
CONCLUSION: This study reveals the anti-tumor potential of mitochondrial transplantation through PTEN/PI3K/AKT signaling pathway to regulate cellular oxidative stress in CCA.PMID:37865041 | DOI:10.1016/j.tice.2023.102243 (Source: Tissue and Cell)
Source: Tissue and Cell - October 21, 2023 Category: Cytology Authors: Xiaocong Liu Yuanyuan Zhang Xiaoyan Yang Yan Zhang Yulan Liu Li Wang Ting Yi Jing Yuan Wu Wen Yi Jian Source Type: research
Alleviation of doxorubicin-induced cardiotoxicity in rat by mesenchymal stem cells and olive leaf extract via MAPK/ TNF- α pathway: Preclinical, experimental and bioinformatics enrichment study
CONCLUSION: Both OLE and BM-MSCs showed an ameliorating effect in rat models of DOX-induced cardiotoxicity, with BM-MSCs showing a greater influence than OLE.PMID:37865037 | DOI:10.1016/j.tice.2023.102239 (Source: Tissue and Cell)
Source: Tissue and Cell - October 21, 2023 Category: Cytology Authors: Mahrous A Ibrahim Athar M Khalifa Noha M Abd El-Fadeal Rehab I Abdel-Karim Ayman F Elsharawy Alia Ellawindy Heba M Galal Eman H Nadwa Mohamed A Abdel-Shafee Rania A Galhom Source Type: research
Apoptotic effects of mesenchymal stem cells' conditioned medium on colorectal cancer cell lines
In conclusion, the conditioned medium from LPS-preconditioned MSCs can effectively induce apoptosis in colorectal cancer cells. This finding suggests that LPS-CM could be a potential strategy for inhibiting the proliferation and progression of colorectal cancer cells.PMID:37865038 | DOI:10.1016/j.tice.2023.102247 (Source: Tissue and Cell)
Source: Tissue and Cell - October 21, 2023 Category: Cytology Authors: Roya Khamooshi Ali Salimi Raheleh Halabian Pardis Saeedi Source Type: research
TNF- α blockage by etanercept restores spatial learning and reduces cellular degeneration in the hippocampus during liver cirrhosis
In conclusion, TNF-α is strongly involved in the development of liver cirrhosis and the associated encephalopathy. TNF-α blockers may be a promising approach for management of hepatic cirrhosis and its cerebral complications.PMID:37865039 | DOI:10.1016/j.tice.2023.102249 (Source: Tissue and Cell)
Source: Tissue and Cell - October 21, 2023 Category: Cytology Authors: Rehab Nady Rasha R Ahmed Nadia Moustafa Manal Abdul-Hamid Source Type: research
Evaluating the protective role of trimetazidine versus nano-trimetazidine in amelioration of bilateral renal ischemia/reperfusion induced neuro-degeneration: Implications of ERK1/2, JNK and Galectin-3 /NF- κB/TNF-α/HMGB-1 signaling
CONCLUSION: Nano-TMZ is more than anti-ischemic.PMID:37865040 | DOI:10.1016/j.tice.2023.102241 (Source: Tissue and Cell)
Source: Tissue and Cell - October 21, 2023 Category: Cytology Authors: Fatma E Hassan Basma Emad Aboulhoda Isra H Ali Heba M Elwi Lamiaa M Matter Hend Ahmed Abdallah Mohamed Mansour Khalifa Asmaa Selmy Mansour A Alghamdi Suzan Awad Morsy Basant A Al Dreny Source Type: research
Mitochondrial transplantation inhibits cholangiocarcinoma cells growth by balancing oxidative stress tolerance through PTEN/PI3K/AKT signaling pathway
CONCLUSION: This study reveals the anti-tumor potential of mitochondrial transplantation through PTEN/PI3K/AKT signaling pathway to regulate cellular oxidative stress in CCA.PMID:37865041 | DOI:10.1016/j.tice.2023.102243 (Source: Tissue and Cell)
Source: Tissue and Cell - October 21, 2023 Category: Cytology Authors: Xiaocong Liu Yuanyuan Zhang Xiaoyan Yang Yan Zhang Yulan Liu Li Wang Ting Yi Jing Yuan Wu Wen Yi Jian Source Type: research
Assessment of breast cytoarchitecture and its associated axillary lymph node status under normal and pathological conditions in Egyptian women
CONCLUSIONS: To sum up, this study emphasizes the importance of accurate specimen evaluation for treatment choice and decision.PMID:37856936 | DOI:10.1016/j.tice.2023.102244 (Source: Tissue and Cell)
Source: Tissue and Cell - October 19, 2023 Category: Cytology Authors: Omnia Mansour Amani Kazem Abeer El Wakil Source Type: research
The marked dextro-dominance causes accentuated morphophysiological variations in the female reproductive organs of the bat Molossus molossus
Tissue Cell. 2023 Oct 15;85:102245. doi: 10.1016/j.tice.2023.102245. Online ahead of print.ABSTRACTMolossus molossus is an insectivorous molossid bat that is important in the control of nocturnal insects. It is the nominal and the most representative species of the family. However, there are few studies about its reproduction. Thus, this study aimed to evaluate variations of its female reproductive organs during the different reproductive phases. Twenty adult females, divided into four sample groups (non-reproductive, early and advanced pregnancy and lactation), were submitted to morphological and morphometric analyses. Re...
Source: Tissue and Cell - October 19, 2023 Category: Cytology Authors: Juliana F Ferraz Rodrigo S de Oliveira Corn élio S Santiago Em ília M Soares Eliana Morielle-Versute Sebasti ão R Taboga Mateus R Beguelini Source Type: research
Assessment of breast cytoarchitecture and its associated axillary lymph node status under normal and pathological conditions in Egyptian women
CONCLUSIONS: To sum up, this study emphasizes the importance of accurate specimen evaluation for treatment choice and decision.PMID:37856936 | DOI:10.1016/j.tice.2023.102244 (Source: Tissue and Cell)
Source: Tissue and Cell - October 19, 2023 Category: Cytology Authors: Omnia Mansour Amani Kazem Abeer El Wakil Source Type: research
The marked dextro-dominance causes accentuated morphophysiological variations in the female reproductive organs of the bat Molossus molossus
Tissue Cell. 2023 Oct 15;85:102245. doi: 10.1016/j.tice.2023.102245. Online ahead of print.ABSTRACTMolossus molossus is an insectivorous molossid bat that is important in the control of nocturnal insects. It is the nominal and the most representative species of the family. However, there are few studies about its reproduction. Thus, this study aimed to evaluate variations of its female reproductive organs during the different reproductive phases. Twenty adult females, divided into four sample groups (non-reproductive, early and advanced pregnancy and lactation), were submitted to morphological and morphometric analyses. Re...
Source: Tissue and Cell - October 19, 2023 Category: Cytology Authors: Juliana F Ferraz Rodrigo S de Oliveira Corn élio S Santiago Em ília M Soares Eliana Morielle-Versute Sebasti ão R Taboga Mateus R Beguelini Source Type: research
Probiotics mixture and taurine attenuate L-arginine-induced acute pancreatitis in rats: Impact on transient receptor potential vanilloid-1 (TRPV-1)/IL-33/NF- κB signaling and apoptosis
Tissue Cell. 2023 Oct 6;85:102234. doi: 10.1016/j.tice.2023.102234. Online ahead of print.ABSTRACTAcute pancreatitis (AP) is an inflammatory disorder of acinar cells. It may develop into severe chronic pancreatitis with a significant mortality rate. The current study aimed to assess the therapeutic effect of a Lactobacillus (LAB) mixture against rat AP. Six groups were created including control, taurine (300 mg/kg; i.p.) for 7 days, LAB mixture for 7 days, L-arginine (2.5 g/kg; i.p.) 2 doses with 1 h interval on 1st day, L-arginine+taurine, and L-arginine+LAB. Serum amylase and lipase activities were measured. Pancreatic t...
Source: Tissue and Cell - October 16, 2023 Category: Cytology Authors: Marvy G Mores Ebtehal Mohammad Fikry Ahmed O El-Gendy Wafaa R Mohamed Osama A Badary Source Type: research
