Ivermectin prevents stress-induced testicular damage in juvenile rats
In conclusion, in addition to be a remarkable antiparasitic agent, ivermectin prevented stress-induced testes injuries in juvenile rats.PMID:38159533 | DOI:10.1016/j.tice.2023.102292 (Source: Tissue and Cell)
Source: Tissue and Cell - December 30, 2023 Category: Cytology Authors: Nathalia A Galv ão Flora Cordeiro Maria M Bernardi Thiago B Kirsten Source Type: research
Ivermectin prevents stress-induced testicular damage in juvenile rats
In conclusion, in addition to be a remarkable antiparasitic agent, ivermectin prevented stress-induced testes injuries in juvenile rats.PMID:38159533 | DOI:10.1016/j.tice.2023.102292 (Source: Tissue and Cell)
Source: Tissue and Cell - December 30, 2023 Category: Cytology Authors: Nathalia A Galv ão Flora Cordeiro Maria M Bernardi Thiago B Kirsten Source Type: research
Ivermectin prevents stress-induced testicular damage in juvenile rats
In conclusion, in addition to be a remarkable antiparasitic agent, ivermectin prevented stress-induced testes injuries in juvenile rats.PMID:38159533 | DOI:10.1016/j.tice.2023.102292 (Source: Tissue and Cell)
Source: Tissue and Cell - December 30, 2023 Category: Cytology Authors: Nathalia A Galv ão Flora Cordeiro Maria M Bernardi Thiago B Kirsten Source Type: research
Elucidating the mechanism of IL-1 β-Mediated Piezo1 expression regulation of chondrocyte autophagy and apoptosis via the PI3K/AKT/mTOR signaling Pathway
Tissue Cell. 2023 Dec 19;86:102291. doi: 10.1016/j.tice.2023.102291. Online ahead of print.ABSTRACTFor the pathogenesis of osteoarthritis (OA), the classical view is that chondrocyte apoptosis is associated with and may cause age-related joint degeneration. Recent observations indicate that Piezo1, a mechanical stress channel expressed in articular cartilage, plays a crucial role in this process. We wanted to investigate whether other conditions activate the expression of Piezo1 in chondrocytes. Therefore, we simulated OA to investigate whether Piezo1 gene expression and channel function were affected by the inflammatory f...
Source: Tissue and Cell - December 22, 2023 Category: Cytology Authors: Wanzhuo Chen Haining Zhang Source Type: research
Establishment of an immortalized cell line derived from human adenomyosis ectopic lesions
This study aimed to establish a line of immortalized human adenomyosis ectopic cell (ihAMEC) to change this situation. Primary cells were obtained from AM ectopic lesion tissue and then infected with Simian Vacuolating Virus 40 Tag (SV40 T) lentivirus and screened to establish immortalized cells. We verified the main features and found that the ihAMEC could be cultured for more than 50 generations and the proliferation ability of ihAMEC was more active than that of primary cells. The cytoskeleton and cell types of ihAMEC were similar to primary cells and maintained a normal karyotype. The expression of epithelial-mesenchym...
Source: Tissue and Cell - December 22, 2023 Category: Cytology Authors: Zilu Wang Fengxin Cui Yinuo Chen Hongyun Liu Yiran Zhang Yaxin Shi Yinuo Zhang Yanfei Wang Na Liang Li Xu Ying Liu Zhiyong Liu Wei Shi Source Type: research
Elucidating the mechanism of IL-1 β-Mediated Piezo1 expression regulation of chondrocyte autophagy and apoptosis via the PI3K/AKT/mTOR signaling Pathway
Tissue Cell. 2023 Dec 19;86:102291. doi: 10.1016/j.tice.2023.102291. Online ahead of print.ABSTRACTFor the pathogenesis of osteoarthritis (OA), the classical view is that chondrocyte apoptosis is associated with and may cause age-related joint degeneration. Recent observations indicate that Piezo1, a mechanical stress channel expressed in articular cartilage, plays a crucial role in this process. We wanted to investigate whether other conditions activate the expression of Piezo1 in chondrocytes. Therefore, we simulated OA to investigate whether Piezo1 gene expression and channel function were affected by the inflammatory f...
Source: Tissue and Cell - December 22, 2023 Category: Cytology Authors: Wanzhuo Chen Haining Zhang Source Type: research
Establishment of an immortalized cell line derived from human adenomyosis ectopic lesions
This study aimed to establish a line of immortalized human adenomyosis ectopic cell (ihAMEC) to change this situation. Primary cells were obtained from AM ectopic lesion tissue and then infected with Simian Vacuolating Virus 40 Tag (SV40 T) lentivirus and screened to establish immortalized cells. We verified the main features and found that the ihAMEC could be cultured for more than 50 generations and the proliferation ability of ihAMEC was more active than that of primary cells. The cytoskeleton and cell types of ihAMEC were similar to primary cells and maintained a normal karyotype. The expression of epithelial-mesenchym...
Source: Tissue and Cell - December 22, 2023 Category: Cytology Authors: Zilu Wang Fengxin Cui Yinuo Chen Hongyun Liu Yiran Zhang Yaxin Shi Yinuo Zhang Yanfei Wang Na Liang Li Xu Ying Liu Zhiyong Liu Wei Shi Source Type: research
Elucidating the mechanism of IL-1 β-Mediated Piezo1 expression regulation of chondrocyte autophagy and apoptosis via the PI3K/AKT/mTOR signaling Pathway
Tissue Cell. 2023 Dec 19;86:102291. doi: 10.1016/j.tice.2023.102291. Online ahead of print.ABSTRACTFor the pathogenesis of osteoarthritis (OA), the classical view is that chondrocyte apoptosis is associated with and may cause age-related joint degeneration. Recent observations indicate that Piezo1, a mechanical stress channel expressed in articular cartilage, plays a crucial role in this process. We wanted to investigate whether other conditions activate the expression of Piezo1 in chondrocytes. Therefore, we simulated OA to investigate whether Piezo1 gene expression and channel function were affected by the inflammatory f...
Source: Tissue and Cell - December 22, 2023 Category: Cytology Authors: Wanzhuo Chen Haining Zhang Source Type: research
Establishment of an immortalized cell line derived from human adenomyosis ectopic lesions
This study aimed to establish a line of immortalized human adenomyosis ectopic cell (ihAMEC) to change this situation. Primary cells were obtained from AM ectopic lesion tissue and then infected with Simian Vacuolating Virus 40 Tag (SV40 T) lentivirus and screened to establish immortalized cells. We verified the main features and found that the ihAMEC could be cultured for more than 50 generations and the proliferation ability of ihAMEC was more active than that of primary cells. The cytoskeleton and cell types of ihAMEC were similar to primary cells and maintained a normal karyotype. The expression of epithelial-mesenchym...
Source: Tissue and Cell - December 22, 2023 Category: Cytology Authors: Zilu Wang Fengxin Cui Yinuo Chen Hongyun Liu Yiran Zhang Yaxin Shi Yinuo Zhang Yanfei Wang Na Liang Li Xu Ying Liu Zhiyong Liu Wei Shi Source Type: research
Elucidating the mechanism of IL-1 β-Mediated Piezo1 expression regulation of chondrocyte autophagy and apoptosis via the PI3K/AKT/mTOR signaling Pathway
Tissue Cell. 2023 Dec 19;86:102291. doi: 10.1016/j.tice.2023.102291. Online ahead of print.ABSTRACTFor the pathogenesis of osteoarthritis (OA), the classical view is that chondrocyte apoptosis is associated with and may cause age-related joint degeneration. Recent observations indicate that Piezo1, a mechanical stress channel expressed in articular cartilage, plays a crucial role in this process. We wanted to investigate whether other conditions activate the expression of Piezo1 in chondrocytes. Therefore, we simulated OA to investigate whether Piezo1 gene expression and channel function were affected by the inflammatory f...
Source: Tissue and Cell - December 22, 2023 Category: Cytology Authors: Wanzhuo Chen Haining Zhang Source Type: research
Establishment of an immortalized cell line derived from human adenomyosis ectopic lesions
This study aimed to establish a line of immortalized human adenomyosis ectopic cell (ihAMEC) to change this situation. Primary cells were obtained from AM ectopic lesion tissue and then infected with Simian Vacuolating Virus 40 Tag (SV40 T) lentivirus and screened to establish immortalized cells. We verified the main features and found that the ihAMEC could be cultured for more than 50 generations and the proliferation ability of ihAMEC was more active than that of primary cells. The cytoskeleton and cell types of ihAMEC were similar to primary cells and maintained a normal karyotype. The expression of epithelial-mesenchym...
Source: Tissue and Cell - December 22, 2023 Category: Cytology Authors: Zilu Wang Fengxin Cui Yinuo Chen Hongyun Liu Yiran Zhang Yaxin Shi Yinuo Zhang Yanfei Wang Na Liang Li Xu Ying Liu Zhiyong Liu Wei Shi Source Type: research
Elucidating the mechanism of IL-1 β-Mediated Piezo1 expression regulation of chondrocyte autophagy and apoptosis via the PI3K/AKT/mTOR signaling Pathway
Tissue Cell. 2023 Dec 19;86:102291. doi: 10.1016/j.tice.2023.102291. Online ahead of print.ABSTRACTFor the pathogenesis of osteoarthritis (OA), the classical view is that chondrocyte apoptosis is associated with and may cause age-related joint degeneration. Recent observations indicate that Piezo1, a mechanical stress channel expressed in articular cartilage, plays a crucial role in this process. We wanted to investigate whether other conditions activate the expression of Piezo1 in chondrocytes. Therefore, we simulated OA to investigate whether Piezo1 gene expression and channel function were affected by the inflammatory f...
Source: Tissue and Cell - December 22, 2023 Category: Cytology Authors: Wanzhuo Chen Haining Zhang Source Type: research
Establishment of an immortalized cell line derived from human adenomyosis ectopic lesions
This study aimed to establish a line of immortalized human adenomyosis ectopic cell (ihAMEC) to change this situation. Primary cells were obtained from AM ectopic lesion tissue and then infected with Simian Vacuolating Virus 40 Tag (SV40 T) lentivirus and screened to establish immortalized cells. We verified the main features and found that the ihAMEC could be cultured for more than 50 generations and the proliferation ability of ihAMEC was more active than that of primary cells. The cytoskeleton and cell types of ihAMEC were similar to primary cells and maintained a normal karyotype. The expression of epithelial-mesenchym...
Source: Tissue and Cell - December 22, 2023 Category: Cytology Authors: Zilu Wang Fengxin Cui Yinuo Chen Hongyun Liu Yiran Zhang Yaxin Shi Yinuo Zhang Yanfei Wang Na Liang Li Xu Ying Liu Zhiyong Liu Wei Shi Source Type: research
Elucidating the mechanism of IL-1 β-Mediated Piezo1 expression regulation of chondrocyte autophagy and apoptosis via the PI3K/AKT/mTOR signaling Pathway
Tissue Cell. 2023 Dec 19;86:102291. doi: 10.1016/j.tice.2023.102291. Online ahead of print.ABSTRACTFor the pathogenesis of osteoarthritis (OA), the classical view is that chondrocyte apoptosis is associated with and may cause age-related joint degeneration. Recent observations indicate that Piezo1, a mechanical stress channel expressed in articular cartilage, plays a crucial role in this process. We wanted to investigate whether other conditions activate the expression of Piezo1 in chondrocytes. Therefore, we simulated OA to investigate whether Piezo1 gene expression and channel function were affected by the inflammatory f...
Source: Tissue and Cell - December 22, 2023 Category: Cytology Authors: Wanzhuo Chen Haining Zhang Source Type: research
Establishment of an immortalized cell line derived from human adenomyosis ectopic lesions
This study aimed to establish a line of immortalized human adenomyosis ectopic cell (ihAMEC) to change this situation. Primary cells were obtained from AM ectopic lesion tissue and then infected with Simian Vacuolating Virus 40 Tag (SV40 T) lentivirus and screened to establish immortalized cells. We verified the main features and found that the ihAMEC could be cultured for more than 50 generations and the proliferation ability of ihAMEC was more active than that of primary cells. The cytoskeleton and cell types of ihAMEC were similar to primary cells and maintained a normal karyotype. The expression of epithelial-mesenchym...
Source: Tissue and Cell - December 22, 2023 Category: Cytology Authors: Zilu Wang Fengxin Cui Yinuo Chen Hongyun Liu Yiran Zhang Yaxin Shi Yinuo Zhang Yanfei Wang Na Liang Li Xu Ying Liu Zhiyong Liu Wei Shi Source Type: research
