Biological and pharmacological properties of myrtenol: a review
Curr Pharm Des. 2022 Dec 22. doi: 10.2174/1381612829666221222121041. Online ahead of print.ABSTRACTMyrtenol (C10H16O) is a volatile compound belonging to the terpenoid family of monocyclic monoterpenes. It is one of the essential oils constituents of several aromatic plants, including the genera Myrtus, Tanacetum, Artemisia, Hyssopus, and Rhodiola. The oxidation of α-pinene can produce it. Several reports demonstrated the pharmacological properties of myrtenol, including its antioxidant, antibacterial, antifungal, antidiabetic, anxiolytic, and gastroprotective activities. In this review, we discussed and highlighted in de...
Source: Current Pharmaceutical Design - December 25, 2022 Category: Drugs & Pharmacology Authors: Hanae Naceiri Mrabti Imane Jaouadi Ikrame Zeouk Rokia Ghchime Naoual El Mniyi Nasreddine El Omari Abdelaali Balahbib Samiah H Al-Mijalli Emad M Abdallah Mohamed El-Shazly Gokhan Zengin Abdelhakim Bouyahya Source Type: research
Biological and pharmacological properties of myrtenol: a review
Curr Pharm Des. 2022 Dec 22. doi: 10.2174/1381612829666221222121041. Online ahead of print.ABSTRACTMyrtenol (C10H16O) is a volatile compound belonging to the terpenoid family of monocyclic monoterpenes. It is one of the essential oils constituents of several aromatic plants, including the genera Myrtus, Tanacetum, Artemisia, Hyssopus, and Rhodiola. The oxidation of α-pinene can produce it. Several reports demonstrated the pharmacological properties of myrtenol, including its antioxidant, antibacterial, antifungal, antidiabetic, anxiolytic, and gastroprotective activities. In this review, we discussed and highlighted in de...
Source: Current Pharmaceutical Design - December 25, 2022 Category: Drugs & Pharmacology Authors: Hanae Naceiri Mrabti Imane Jaouadi Ikrame Zeouk Rokia Ghchime Naoual El Mniyi Nasreddine El Omari Abdelaali Balahbib Samiah H Al-Mijalli Emad M Abdallah Mohamed El-Shazly Gokhan Zengin Abdelhakim Bouyahya Source Type: research
Biological and pharmacological properties of myrtenol: a review
Curr Pharm Des. 2022 Dec 22. doi: 10.2174/1381612829666221222121041. Online ahead of print.ABSTRACTMyrtenol (C10H16O) is a volatile compound belonging to the terpenoid family of monocyclic monoterpenes. It is one of the essential oils constituents of several aromatic plants, including the genera Myrtus, Tanacetum, Artemisia, Hyssopus, and Rhodiola. The oxidation of α-pinene can produce it. Several reports demonstrated the pharmacological properties of myrtenol, including its antioxidant, antibacterial, antifungal, antidiabetic, anxiolytic, and gastroprotective activities. In this review, we discussed and highlighted in de...
Source: Current Pharmaceutical Design - December 25, 2022 Category: Drugs & Pharmacology Authors: Hanae Naceiri Mrabti Imane Jaouadi Ikrame Zeouk Rokia Ghchime Naoual El Mniyi Nasreddine El Omari Abdelaali Balahbib Samiah H Al-Mijalli Emad M Abdallah Mohamed El-Shazly Gokhan Zengin Abdelhakim Bouyahya Source Type: research
Research Progress of Chinese Medicine in the Treatment of Myocardial Ischemia-Reperfusion Injury
Am J Chin Med. 2022 Nov 28:1-17. doi: 10.1142/S0192415X23500015. Online ahead of print.ABSTRACTVascular recanalization is the essential procedure in which severe coronary artery stenosis is diagnosed. However, the blood flow recovery associated with this procedure may cause myocardial ischemia-reperfusion injury (MIRI), which aggravates heart failure. Unfortunately, the mechanism of MIRI has historically been poorly understood. As we now know, calcium overloading, oxidative stress, mitochondrial dysfunction, inflammatory responses, and ferroptosis take part in the process of MIRI. Modern medicine has shown through clinical...
Source: The American Journal of Chinese Medicine - November 28, 2022 Category: Complementary Medicine Authors: Li Dong Zhijie Shen Hao Chi Yingjie Wang Zhaofeng Shi Hongjun Fang Yanling Yang Jingfeng Rong Source Type: research
Research Progress of Chinese Medicine in the Treatment of Myocardial Ischemia-Reperfusion Injury
Am J Chin Med. 2022 Nov 28:1-17. doi: 10.1142/S0192415X23500015. Online ahead of print.ABSTRACTVascular recanalization is the essential procedure in which severe coronary artery stenosis is diagnosed. However, the blood flow recovery associated with this procedure may cause myocardial ischemia-reperfusion injury (MIRI), which aggravates heart failure. Unfortunately, the mechanism of MIRI has historically been poorly understood. As we now know, calcium overloading, oxidative stress, mitochondrial dysfunction, inflammatory responses, and ferroptosis take part in the process of MIRI. Modern medicine has shown through clinical...
Source: The American Journal of Chinese Medicine - November 28, 2022 Category: Complementary Medicine Authors: Li Dong Zhijie Shen Hao Chi Yingjie Wang Zhaofeng Shi Hongjun Fang Yanling Yang Jingfeng Rong Source Type: research
Research Progress of Chinese Medicine in the Treatment of Myocardial Ischemia-Reperfusion Injury
Am J Chin Med. 2022 Nov 28:1-17. doi: 10.1142/S0192415X23500015. Online ahead of print.ABSTRACTVascular recanalization is the essential procedure in which severe coronary artery stenosis is diagnosed. However, the blood flow recovery associated with this procedure may cause myocardial ischemia-reperfusion injury (MIRI), which aggravates heart failure. Unfortunately, the mechanism of MIRI has historically been poorly understood. As we now know, calcium overloading, oxidative stress, mitochondrial dysfunction, inflammatory responses, and ferroptosis take part in the process of MIRI. Modern medicine has shown through clinical...
Source: The American Journal of Chinese Medicine - November 28, 2022 Category: Complementary Medicine Authors: Li Dong Zhijie Shen Hao Chi Yingjie Wang Zhaofeng Shi Hongjun Fang Yanling Yang Jingfeng Rong Source Type: research
Polyketides with anti-inflammatory activity isolated from Rhodiola tibetica endophytic fungus Penicillium sp. HJT-A-10
Fitoterapia. 2022 Nov 23:105361. doi: 10.1016/j.fitote.2022.105361. Online ahead of print.ABSTRACTSeven undescribed polyketide compounds (1-4, 9-11) and six known polyketide compounds (5-8,12, 13) were isolated from Rhodiola tibetica endophytic Penicillium sp. HJT-A-10. The structural of seven undescribed polyketides metabolites were established on the basis of spectroscopic methods. The results of anti-inflammatory activity showed that compounds 1-8，10-13 had significant inhibitory effects on LPS-induced NO production in RAW 264.7 cells.PMID:36435487 | DOI:10.1016/j.fitote.2022.105361 (Source: Fitoterapia)
Source: Fitoterapia - November 26, 2022 Category: Biochemistry Authors: Xuan Lu Jun-Kai Qi Xiao-Yuan Tang Xu-de Wang Chong-Tao Ye Jing Bai Chuan Tang Yu-Fei Xi Bin Wu Xue Wan Bao-Min Feng Source Type: research
Salidroside attenuates cerebral ischemia/reperfusion injury by regulating TSC2-induced autophagy
In conclusion, SAL reduces the inflammatory response and oxidative stress in a concentration-dependent manner, and protects against cerebral I/R injury by modulating TSC2-induced autophagy. These findings suggest SAL may prove to be a potential therapeutic agent for ischemic stroke.PMID:36374318 | DOI:10.1007/s00221-022-06493-6 (Source: Brain Research)
Source: Brain Research - November 14, 2022 Category: Neurology Authors: Chunli Li Jiejun Chi Hongyan Dai Ming Liang Yangyang Wang Songxin Tian Huiyan Zhu Hai Xu Source Type: research
Salidroside attenuates cerebral ischemia/reperfusion injury by regulating TSC2-induced autophagy
In conclusion, SAL reduces the inflammatory response and oxidative stress in a concentration-dependent manner, and protects against cerebral I/R injury by modulating TSC2-induced autophagy. These findings suggest SAL may prove to be a potential therapeutic agent for ischemic stroke.PMID:36374318 | DOI:10.1007/s00221-022-06493-6 (Source: Experimental Brain Research)
Source: Experimental Brain Research - November 14, 2022 Category: Neuroscience Authors: Chunli Li Jiejun Chi Hongyan Dai Ming Liang Yangyang Wang Songxin Tian Huiyan Zhu Hai Xu Source Type: research
Salidroside attenuates cerebral ischemia/reperfusion injury by regulating TSC2-induced autophagy
In conclusion, SAL reduces the inflammatory response and oxidative stress in a concentration-dependent manner, and protects against cerebral I/R injury by modulating TSC2-induced autophagy. These findings suggest SAL may prove to be a potential therapeutic agent for ischemic stroke.PMID:36374318 | DOI:10.1007/s00221-022-06493-6 (Source: Cell Research)
Source: Cell Research - November 14, 2022 Category: Cytology Authors: Chunli Li Jiejun Chi Hongyan Dai Ming Liang Yangyang Wang Songxin Tian Huiyan Zhu Hai Xu Source Type: research
Salidroside attenuates cerebral ischemia/reperfusion injury by regulating TSC2-induced autophagy
In conclusion, SAL reduces the inflammatory response and oxidative stress in a concentration-dependent manner, and protects against cerebral I/R injury by modulating TSC2-induced autophagy. These findings suggest SAL may prove to be a potential therapeutic agent for ischemic stroke.PMID:36374318 | DOI:10.1007/s00221-022-06493-6 (Source: Brain Research)
Source: Brain Research - November 14, 2022 Category: Neurology Authors: Chunli Li Jiejun Chi Hongyan Dai Ming Liang Yangyang Wang Songxin Tian Huiyan Zhu Hai Xu Source Type: research
Salidroside attenuates cerebral ischemia/reperfusion injury by regulating TSC2-induced autophagy
In conclusion, SAL reduces the inflammatory response and oxidative stress in a concentration-dependent manner, and protects against cerebral I/R injury by modulating TSC2-induced autophagy. These findings suggest SAL may prove to be a potential therapeutic agent for ischemic stroke.PMID:36374318 | DOI:10.1007/s00221-022-06493-6 (Source: Experimental Brain Research)
Source: Experimental Brain Research - November 14, 2022 Category: Neuroscience Authors: Chunli Li Jiejun Chi Hongyan Dai Ming Liang Yangyang Wang Songxin Tian Huiyan Zhu Hai Xu Source Type: research
Salidroside attenuates cerebral ischemia/reperfusion injury by regulating TSC2-induced autophagy
In conclusion, SAL reduces the inflammatory response and oxidative stress in a concentration-dependent manner, and protects against cerebral I/R injury by modulating TSC2-induced autophagy. These findings suggest SAL may prove to be a potential therapeutic agent for ischemic stroke.PMID:36374318 | DOI:10.1007/s00221-022-06493-6 (Source: Experimental Brain Research)
Source: Experimental Brain Research - November 14, 2022 Category: Neuroscience Authors: Chunli Li Jiejun Chi Hongyan Dai Ming Liang Yangyang Wang Songxin Tian Huiyan Zhu Hai Xu Source Type: research
New Metabolites of Rhodiola rosea I. Glycosides of Herbacetin and Gossypetin
New O-glycosides of herbacetin and gossypetin (1–6) and eight known compounds were isolated from leaves ofRhodiola rosea L. [Sedum roseum (L.) Scop., Crassulaceae]. According to UV, IR, and NMR spectroscopic and mass spectrometric data, the isolated compounds were herbacetin-3-O-(3 ′′ -O-malonyl)-β-Dglucopyranoside-7-O-β-D-glucopyranoside-8-O-β-D-glucuronopyranoside (rhodirosin A,1), herbacetin- 3-O-(3 ′′,4′′-di-O-acetyl)-β-D-glucopyranoside-8-O-β-D-glucuronopyranoside (rhodirosin B,2), gossypetin- 8-O-(2 ′′-O-malonyl)-β-D-glucuronopyranoside (rhodirosin C,3), gossypetin-8-O-(2 ′′-O-acetyl)-β-D...
Source: Chemistry of Natural Compounds - November 10, 2022 Category: Chemistry Source Type: research
Molecules, Vol. 27, Pages 7487: Antihypothyroid Effect of Salidroside
na V. Terletskaya
In terms of prevalence, thyroid pathology, associated both with a violation of the gland function and changes in its structure, occupies one of the main places in clinical endocrinology. The problem of developing low-toxic and highly effective herbal preparations for the correction of thyroid hypofunction and its complications is urgent. Salidroside is a glucoside of tyrosol, found mostly in the roots of Rhodiola spp., and has various positive biological activities. The purpose of this study was to study the antihypothyroid potential of salidrosid-containing extract from R. semenovii roots, which was ...
Source: Molecules - November 2, 2022 Category: Chemistry Authors: Nazym K. Korbozova Nataliya O. Kudrina Nataliya A. Zhukova Alexander E. Grazhdannikov Irina V. Blavachinskaya Gulnaz A. Seitimova Timur E. Kulmanov Tatyana G. Tolstikova Nina V. Terletskaya Tags: Article Source Type: research
