Salidroside promotes pro-angiogenesis and repair of blood brain barrier via Notch/ITGB1 signal path in CSVD Model
CONCLUSION: The aforementioned findings demonstrated that SAL could protect BBB integrity through Notch-ITGB1 signaling path in CSVD, which indicated that SAL could be a potential medicine candidate for CSVD treatment.PMID:38417575 | DOI:10.1016/j.jare.2024.02.019 (Source: Cell Research)
Source: Cell Research - February 28, 2024 Category: Cytology Authors: Tu Zhilan Zhang Zengyu Jin Pengpeng Yang Hualan Li Chao Xi Yan Guo Zimin Hou Shuangxing Li Weiwei Source Type: research
Ameliorative effect of salidroside on the cyclophosphamide-induced premature ovarian failure in a rat model
Conclusions：Salidroside therapy improved premature ovarian failure significantly through antioxidant function and activating Nrf2 signaling.PMID:38408280 | DOI:10.1080/10715762.2024.2320383 (Source: Free Radical Research)
Source: Free Radical Research - February 26, 2024 Category: Research Authors: Lixuan Chen Qinglin Mo Yingnan Wu Wancheng Chen Kaixian Deng Yang Xiao Source Type: research
Molecules, Vol. 29, Pages 866: Anti-Neuroinflammatory Effects of Adaptogens: A Mini-Review
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Introduction: Adaptogens are a group of plants that exhibit complex, nonspecific effects on the human body, increasing its ability to adapt, develop resilience, and survive in stress conditions. They are found in many traditional medicinal systems and play a key role in restoring the body’s strength and stamina. Research in recent years has attempted to elucidate the mechanisms behind their pharmacological effects, but it appears that these effects are difficult to define precisely and involve multiple molecular pathways. Neuroinflammation: In recent years, chronic inflammation has been recognized as o...
Source: Molecules - February 15, 2024 Category: Chemistry Authors: Dagmara Wr óbel-Biedrawa Irma Podolak Tags: Review Source Type: research
Effects of the PREMEN-CALM ® in the Management of the Premenstrual Syndrome: A Randomized, Double-Blind, Placebo-Controlled Pilot Study
J Diet Suppl. 2024 Jan 11:1-17. doi: 10.1080/19390211.2023.2301398. Online ahead of print.ABSTRACTPremenstrual syndrome is a common disorder in women of reproductive age characterized by a variety of cyclical symptoms with a great impact on their lifestyle. Available pharmacological options include both antidepressants and oral contraceptives, both of which have side effects, are expensive and not always effective. Vitamins, minerals and plant extracts have been proven to alleviate the symptomatology of the premenstrual syndrome. For this reason, the purpose of this study was to test the effectiveness of a commercial phyto...
Source: Journal of Dietary Supplements - January 12, 2024 Category: Nutrition Authors: Andrea Herrera Miriam Al Adib Ana Beatriz Rodr íguez Cristina Carrasco Source Type: research
Hormesis determines lifespan
Ageing Res Rev. 2024 Jan 3:102181. doi: 10.1016/j.arr.2023.102181. Online ahead of print.ABSTRACTThis paper addresses how long lifespan can be extended via multiple interventions, such as dietary supplements [e.g., curcumin, resveratrol, sulforaphane, complex phytochemical mixtures (e.g., Moringa, Rhodiola)], pharmaceutical agents (e.g., metformin), caloric restriction, intermittent fasting, exercise and other activities. This evaluation was framed within the context of hormesis, a biphasic dose response with specific quantitative features describing the limits of biological/phenotypic plasticity for integrative biological...
Source: Ageing Research Reviews - January 5, 2024 Category: Genetics & Stem Cells Authors: Edward J Calabrese Marc Nascarella Peter Pressman A Wallace Hayes Gaurav Dhawan Rachna Kapoor Vittorio Calabrese Evgenios Agathokleous Source Type: research
Hormesis determines lifespan
Ageing Res Rev. 2024 Jan 3:102181. doi: 10.1016/j.arr.2023.102181. Online ahead of print.ABSTRACTThis paper addresses how long lifespan can be extended via multiple interventions, such as dietary supplements [e.g., curcumin, resveratrol, sulforaphane, complex phytochemical mixtures (e.g., Moringa, Rhodiola)], pharmaceutical agents (e.g., metformin), caloric restriction, intermittent fasting, exercise and other activities. This evaluation was framed within the context of hormesis, a biphasic dose response with specific quantitative features describing the limits of biological/phenotypic plasticity for integrative biological...
Source: Ageing Research Reviews - January 5, 2024 Category: Genetics & Stem Cells Authors: Edward J Calabrese Marc Nascarella Peter Pressman A Wallace Hayes Gaurav Dhawan Rachna Kapoor Vittorio Calabrese Evgenios Agathokleous Source Type: research
Hormesis determines lifespan
Ageing Res Rev. 2024 Jan 3:102181. doi: 10.1016/j.arr.2023.102181. Online ahead of print.ABSTRACTThis paper addresses how long lifespan can be extended via multiple interventions, such as dietary supplements [e.g., curcumin, resveratrol, sulforaphane, complex phytochemical mixtures (e.g., Moringa, Rhodiola)], pharmaceutical agents (e.g., metformin), caloric restriction, intermittent fasting, exercise and other activities. This evaluation was framed within the context of hormesis, a biphasic dose response with specific quantitative features describing the limits of biological/phenotypic plasticity for integrative biological...
Source: Cell Research - January 5, 2024 Category: Cytology Authors: Edward J Calabrese Marc Nascarella Peter Pressman A Wallace Hayes Gaurav Dhawan Rachna Kapoor Vittorio Calabrese Evgenios Agathokleous Source Type: research
