Rhodiola rosea: A Therapeutic Candidate on Cardiovascular Diseases
This article reviews the research on the pharmacological effects of Rhodiola rosea on cardiovascular diseases and provides references for the clinical treatment of cardiovascular diseases.PMID:35265260 | PMC:PMC8898776 | DOI:10.1155/2022/1348795 (Source: Atherosclerosis)
Source: Atherosclerosis - March 10, 2022 Category: Cardiology Authors: Yingqing Chen Minli Tang Shuo Yuan Shuang Fu Yifei Li You Li Qi Wang Yuying Cao Liping Liu Qinggao Zhang Source Type: research

Rhodiola rosea: A Therapeutic Candidate on Cardiovascular Diseases
This article reviews the research on the pharmacological effects of Rhodiola rosea on cardiovascular diseases and provides references for the clinical treatment of cardiovascular diseases.PMID:35265260 | PMC:PMC8898776 | DOI:10.1155/2022/1348795 (Source: Atherosclerosis)
Source: Atherosclerosis - March 10, 2022 Category: Cardiology Authors: Yingqing Chen Minli Tang Shuo Yuan Shuang Fu Yifei Li You Li Qi Wang Yuying Cao Liping Liu Qinggao Zhang Source Type: research

Enhancement of Swimming Endurance by Herbal Supplement M3P
ConclusionM3P supplementation may improve swimming endurance accompanied by increasing hepatic glycogen content and serum cortisol level without major toxicity. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - January 20, 2022 Category: Internal Medicine Source Type: research

Salidroside prevents PM2.5-induced BEAS-2B cell apoptosis via SIRT1-dependent regulation of ROS and mitochondrial function
Ecotoxicol Environ Saf. 2022 Jan 10;231:113170. doi: 10.1016/j.ecoenv.2022.113170. Online ahead of print.ABSTRACTPM2.5 is a harmful air pollutant currently threatening public health. It has been closely linked to increased morbidity of bronchial asthma and lung cancer worldwide. Salidroside (Sal), an active component extracted from Rhodiola rosea, has been reported to ameliorate the progression of asthma. However, there are few studies on the protective effect of salidroside on PM2.5-induced bronchial epithelial cell injury, and the related molecular mechanism is not clear. Here, we aimed to explore the protective effect a...
Source: Ecotoxicology and Environmental Safety - January 13, 2022 Category: Environmental Health Authors: Hui Shan Xiaohong Li Chuan Ouyang Hongyang Ke Xiaoli Yu Jinfeng Tan Junhao Chen Chunping Wang Liping Zhang Yunfeng Tang Li Yu Wanwei Li Source Type: research

Green synthesis of silver nanoparticles using Rhodiola imbricata and Withania somnifera root extract and their potential catalytic, antioxidant, cytotoxic and growth-promoting activities
This study presents the development of a sustainable production process of environmentally benign silver nanoparticles (AgNPs) from aqueous root extract of Rhodiola imbricata (RI) and Withania somnifera (WS) for mitigating environmental pollution and investigating their potential applications in agriculture and biomedical industry. RIWS-AgNPs were characterized using several analytical techniques (UV-Vis, DLS, HR-TEM, SAED, EDX and FTIR). The antioxidant and anticancer activity of RIWS-AgNPs were estimated by DPPH and MTT assay, respectively. UV-Vis and DLS analysis indicated that equal ratio of RIWS-extract and silver nit...
Source: Bioprocess and Biosystems Engineering - January 6, 2022 Category: Biomedical Engineering Authors: Sahil Kapoor Hemant Sood Shweta Saxena Om Prakash Chaurasia Source Type: research

Neuroprotective Effects of Rhodiola Sacra on Transient Global Cerebral Ischemia Through Activating AMPK/Nrf2 Pathway in Rats
Antioxidants&Redox Signaling, Ahead of Print. (Source: Antioxidants and Redox Signaling)
Source: Antioxidants and Redox Signaling - January 4, 2022 Category: Research Authors: Kongping Li Jiaqi Jiang Zhe Shi Lixuan Zhan Linhui Peng Weiwen Sun Yanyan Tang Xialin Zuo En Xu Source Type: research

Salidroside promotes the osteogenic and odontogenic differentiation of human dental pulp stem cells through the BMP signaling pathway
Exp Ther Med. 2022 Jan;23(1):55. doi: 10.3892/etm.2021.10977. Epub 2021 Nov 17.ABSTRACTRegenerative endodontics, as an alternative approach, aims to regenerate dental pulp-like tissues and is garnering the attention of clinical dentists. This is due to its reported biological benefits for dental therapeutics. Stem cells and their microenvironment serve an important role in the process of pulp regeneration. Regulation of the stem cell microenvironment and the directed differentiation of stem cells is becoming a topic of intensive research. Salidroside (SAL) is extracted from the root of Rhodiola rosea and it has been report...
Source: Experimental and Therapeutic Medicine - December 17, 2021 Category: General Medicine Authors: Xiaoling Wei Jiayang Li Hui Liu Chenguang Niu Dong Chen Source Type: research

Avens Root (Geum Urbanum L.) Extract Discovered by Target-Based Screening Exhibits Antidiabetic Activity in the Hen ’s Egg Test Model and Drosophila melanogaster
In conclusion, avens root extract represents a promising medicinal plant that should be considered in further in-vivo studies on hyperglycemia in laboratory rodents and humans. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - December 15, 2021 Category: Drugs & Pharmacology Source Type: research

Molecules, Vol. 26, Pages 7383: Altitudinal Variation of Metabolites, Mineral Elements and Antioxidant Activities of Rhodiola crenulata(Hook.f. & amp; Thomson) H.Ohba
In this study, the response of Rhodiola crenulata to differences in altitude gradients was investigated through chemical, ICP-MS and metabolomic methods. A targeted study of Rhodiola crenulata growing at three vertical altitudes revealed that the contents of seven elements Ca, Sr, B, Mn, Ni, Cu, and Cd, the phenolic components, the ascorbic acid, the ascorbic acid/dehydroascorbate ratio, and the antioxidant capacity were positively correlated with altitude, while the opposite was true for total ascorbic acid content. Furthermore, 1165 metabolites were identified: flavonoids (200), gallic acids (30), phenylpropanoids (237),...
Source: Molecules - December 5, 2021 Category: Chemistry Authors: Tingting Dong Yueqi Sha Hairong Liu Liwei Sun Tags: Article Source Type: research

Uncovering the Metabolic Mechanism of Salidroside Alleviating Microglial Hypoxia Inflammation Based on Microfluidic Chip-Mass Spectrometry
J Proteome Res. 2021 Dec 1. doi: 10.1021/acs.jproteome.1c00647. Online ahead of print.ABSTRACTMicroglia are the main immune cells in the brain playing a critical role in neuroinflammation, and numerous pieces of evidence have proved that energy metabolism is closely associated with inflammation in activated microglia. Salidroside (Sal) isolated from Tibetan medicine Rhodiola crenulate can inhibit microglial hypoxia inflammation (HI). However, whether the inhibition is due to the intervening energy metabolic process in microglia is not clear. In this work, the hypoxic microenvironment of BV2 microglial cells was simulated u...
Source: Cell Research - December 1, 2021 Category: Cytology Authors: Fangfang Fan Ning Xu Yucheng Sun Xuanhao Li Xinchang Gao Xizhen Yi Yi Zhang Xianli Meng Jin-Ming Lin Source Type: research

Molecules, Vol. 26, Pages 6855: Application of UHPLC Fingerprints Combined with Chemical Pattern Recognition Analysis in the Differentiation of Six Rhodiola Species
In this study, a simple and efficient method of the classification of Rhodiola crenulate, Rhodiola rosea, and their confusable species (Rhodiola serrata, Rhodiola yunnanensis, Rhodiola kirilowii and Rhodiola fastigiate) was established by UHPLC fingerprints combined with chemical pattern recognition analysis. The results showed that similarity analysis and principal component analysis (PCA) could not achieve accurate classification among the six Rhodiola species. Linear discriminant analysis (LDA) combined with stepwise feature selection exhibited effective discrimination. Seven characteristic peaks that are responsible fo...
Source: Molecules - November 13, 2021 Category: Chemistry Authors: Didi Ma Lijun Wang Yibao Jin Lifei Gu Xiean Yu Xueqing Xie Guo Yin Jue Wang Kaishun Bi Yi Lu Tiejie Wang Tags: Article Source Type: research