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Salidroside affects the Th17/Treg cell balance in aplastic anemia via the STAT3/HIF-1 α/RORγt pathway
CONCLUSION: Salidroside has potential as a novel AA treatment by correcting the Th17/Treg imbalance through the STAT3/HIF-1α/RORγt pathway.PMID:37439434 | PMC:PMC10348039 | DOI:10.1080/13510002.2023.2225868 (Source: Redox Report : communications in free radical research)
Source: Redox Report : communications in free radical research - July 13, 2023 Category: Biochemistry Authors: Zenghui Liu Lixuan Chen Defang Xiong Yu Zhan Jiduo Liu Ling Ouyang Wancheng Chen Ziyuan Lu Tianqi Gao Xiaozhen Li Yanqun Zhou Xuekui Gu Yang Xiao Source Type: research

Salidroside suppresses the multiple oncogenic activates and immune escape of lung adenocarcinoma through the circ_0009624 ‐mediated PD‐L1 pathway
ConclusionApplying SAL might constrain malignant phenotypes and immune escape of LUAD cells partially through the circ_0009624-mediated PD-L1 pathway, providing a novel insight for LUAD treatment. (Source: Thoracic Cancer)
Source: Thoracic Cancer - July 9, 2023 Category: Cancer & Oncology Authors: Guilin Jin, Mi Ma, Chunyan Yang, Luo Zhen, Mingke Feng Tags: ORIGINAL ARTICLE Source Type: research

Molecules, Vol. 28, Pages 5053: Rhodiola rosea L. Extract, A Known Adaptogen, Evaluated in Experimental Arthritis
ilvester Ponist Rhodiola rosea L. extract (RSE) is mostly known for its adaptogen properties, but not for its antiarthritic activities, therefore monotherapy and combination with low-dose methotrexate (MTX) was studied. The collagen-induced arthritis (CIA) model was used to measure the functional score, and the change in hind paw volume (HPV). Both parameters had significant antiarthritic effects. Based on these preliminary results, an adjuvant arthritis (AA) model was further applied to assess another parameters. The experiment included these animal groups: healthy controls, untreated AA, AA administered with RSE (150...
Source: Molecules - June 28, 2023 Category: Chemistry Authors: Frantisek Drafi Katarina Bauerova Martin Chrastina Mohsen Taghdisiesfej ír Jo ão Rocha Rosa Direito Maria Eduardo Figueira Bruno Sepodes Silvester Ponist Tags: Article Source Type: research

Mechanism of salidroside against coronary artery disease by network pharmacology analysis
This study w... (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - June 12, 2023 Category: Complementary Medicine Authors: Lin Tao, Zhi-Fang Liang, Liu Miao, Yu-Jie Guo, Ye Li, Yan-Li Liu, Dong-Ming Fang and Zhi-Jie Yang Tags: Research Source Type: research

Salidroside alleviates oxidative stress in dry eye disease by activating autophagy through AMPK-Sirt1 pathway
In conclusion, our data suggest that salidroside is a promising candidate for DED treatment.PMID:37302369 | DOI:10.1016/j.intimp.2023.110397 (Source: International Immunopharmacology)
Source: International Immunopharmacology - June 11, 2023 Category: Allergy & Immunology Authors: Qi Liang Rongjie Guo Jia-Ruei Tsao Yun He Chenchen Wang Jiaxuan Jiang Di Zhang Taige Chen Tingting Yue Kai Hu Source Type: research