Effects of Ketamine on Postoperative Pain After Remifentanil-Based Anesthesia for Major and Minor Surgery in Adults: A Systematic Review and Meta-Analysis
Juan F. Garc ía-Henares, Jose A. Moral-Munoz, Alejandro Salazar, Esperanza Del Pozo (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 17, 2018 Category: Drugs & Pharmacology Source Type: research

Mitochondrial-Targeting Anticancer Agent Conjugates and Nanocarrier Systems for Cancer Treatment
Gantumur Battogtokh, Yong-Yeon Cho, Joo Young Lee, Hye Suk Lee, Han Chang Kang (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 17, 2018 Category: Drugs & Pharmacology Source Type: research

miR-133: A Suppressor of Cardiac Remodeling?
Ning Li, Heng Zhou, Qizhu Tang (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 17, 2018 Category: Drugs & Pharmacology Source Type: research

Sp1, Instead of AhR, Regulates the Basal Transcription of Porcine CYP1A1 at the Proximal Promoter
Xuan Xie, Jun Jiang, Wenchu Ye, Ruohong Chen, Yiqun Deng, Jikai Wen (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 17, 2018 Category: Drugs & Pharmacology Source Type: research

Fengshi Gutong Capsule Attenuates Osteoarthritis by Inhibiting MAPK, NF- κB, AP-1, and Akt Pathways
Yao-Xin Gao, Hao-Heng Yu, Chuan He, Ming Li, Dan-Dan Guo, Jun-Jiang Lian, Hai-Jie Yang, Mian Wang, Lei Wang, Zhi-Wei Feng, Bin-Feng Cheng (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 17, 2018 Category: Drugs & Pharmacology Source Type: research

Isoliquiritigenin Protects Against Pancreatic Injury and Intestinal Dysfunction After Severe Acute Pancreatitis via Nrf2 Signaling
Man Zhang, Yan-Qing Wu, Ling Xie, Jiang Wu, Ke Xu, Jian Xiao, Da-Qing Chen (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 17, 2018 Category: Drugs & Pharmacology Source Type: research

A General Overview on Non-coding RNA-Based Diagnostic and Therapeutic Approaches for Liver Diseases
Sanchari Roy, Christian Trautwein, Tom Luedde, Christoph Roderburg (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 15, 2018 Category: Drugs & Pharmacology Source Type: research

Exploring the Mechanism of Flavonoids Through Systematic Bioinformatics Analysis
Tianyi Qiu, Dingfeng Wu, LinLin Yang, Hao Ye, Qiming Wang, Zhiwei Cao, Kailin Tang (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 15, 2018 Category: Drugs & Pharmacology Source Type: research

How Female Mice Attract Males: A Urinary Volatile Amine Activates a Trace Amine-Associated Receptor That Induces Male Sexual Interest
Anja Harmeier, Claas A. Meyer, Andreas Staempfli, Fabio Casagrande, Marija M. Petrinovic, Yan-Ping Zhang, Basil K ünnecke, Antonio Iglesias, Oliver P. Höner, Marius C. Hoener (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 15, 2018 Category: Drugs & Pharmacology Source Type: research

Pathway-Based Drug Repositioning for Breast Cancer Molecular Subtypes
Ra úl A. Mejía-Pedroza, Jesús Espinal-Enríquez, Enrique Hernández-Lemus (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 15, 2018 Category: Drugs & Pharmacology Source Type: research

Poly (ADP-Ribose) Polymerase 1 Mediated Arginase II Activation Is Responsible for Oxidized LDL-Induced Endothelial Dysfunction
Qi Wang, Tong Zhao, Wei Zhang, Wenbin Yu, Bin Liu, Zhaoyang Wang, Wen Qiao, Qinghua Lu, Aihua Wang, Mingxiang Zhang (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 15, 2018 Category: Drugs & Pharmacology Source Type: research

Ligand Bias and Its Association With Pro-resolving Actions of Melanocortin Drugs
Sara Patruno, Jose Garrido-Mesa, Mario Romano, Mauro Perretti, Trinidad Montero-Melendez (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 14, 2018 Category: Drugs & Pharmacology Source Type: research

Preparation of Colon-Targeted Acetylharpagide Tablets and its Release Properties in vivo and in vitro
DeWen Liu, Huijie Yan, Yiming Kong, Yun You, Yanling Li, Lixin Wang, Yan Tong, Jinyu Wang (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 14, 2018 Category: Drugs & Pharmacology Source Type: research

MMP-9 as a Candidate Marker of Response to BRAF Inhibitors in Melanoma Patients With BRAFV600E Mutation Detected in Circulating-Free DNA
Rossella Salemi, Luca Falzone, Gabriele Madonna, Jerry Polesel, Diana Cin à, Domenico Mallardo, Paolo A. Ascierto, Massimo Libra, Saverio Candido (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 14, 2018 Category: Drugs & Pharmacology Source Type: research

Integrated Serum and Fecal Metabolomics Study of Collagen-Induced Arthritis Rats and the Therapeutic Effects of the Zushima Tablet
Jinjun Shan, Linxiu Peng, Wenjuan Qian, Tong Xie, An Kang, Bei Gao, Liuqing Di (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 14, 2018 Category: Drugs & Pharmacology Source Type: research

A Nanomicellar Prodrug Carrier Based on Ibuprofen-Conjugated Polymer for Co-delivery of Doxorubicin
Zuojun Li, Jingjing Sun, Yixian Huang, Yanhua Liu, Jieni Xu, Yichao Chen, Lei Liang, Jiang Li, Qiongfeng Liao, Song Li, Kechao Zhou (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 14, 2018 Category: Drugs & Pharmacology Source Type: research

Preoperative Changes in Hematological Markers and Predictors of Glioma Grade and Survival
Peng-Fei Wang, Zhe Meng, Hong-Wang Song, Kun Yao, Ze-Jun Duan, Chun-Jiang Yu, Shou-Wei Li, Chang-Xiang Yan (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 14, 2018 Category: Drugs & Pharmacology Source Type: research

Advantages and Limitations of Current Techniques for Analyzing the Biodistribution of Nanoparticles
Lauren Arms, Doug W. Smith, Jamie Flynn, William Palmer, Antony Martin, Ameha Woldu, Susan Hua (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 14, 2018 Category: Drugs & Pharmacology Source Type: research

Controlled Drug Delivery by Polylactide Stereocomplex Micelle for Cervical Cancer Chemotherapy
Kai Niu, Yunming Yao, Ming Xiu, Chunjie Guo, Yuanyuan Ge, Jianmeng Wang (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 14, 2018 Category: Drugs & Pharmacology Source Type: research

Assessing the efficacy of lopinavir/ritonavir-based preferred and alternative second-line regimens in HIV-infected patients: a meta-analysis on key evidence to support WHO recommendations
Yinqiu Huang, Xiaojie Huang, Yadong Luo, Yihong Zhou, Xingbao Tao, Hui Chen, Aixin Song, Yaokai Chen, Hao WU (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 14, 2018 Category: Drugs & Pharmacology Source Type: research

Sensitivity of Entomopathogenic Fungi and Bacteria to Plants Secondary Metabolites, for an Alternative Control of Rhipicephalus (Boophilus) microplus in Cattle
Simona Nardoni, Valentina V. Ebani, Carlo D ’Ascenzi, Luisa Pistelli, Francesca Mancianti (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 14, 2018 Category: Drugs & Pharmacology Source Type: research

Valepotriates From the Roots and Rhizomes of Valeriana jatamansi Jones as Novel N-Type Calcium Channel Antagonists
Fa-Wu Dong, He-Hai Jiang, Liu Yang, Ye Gong, Cheng-Ting Zi, Dan Yang, Chen-Jun Ye, Huan Li, Jian Yang, Yin Nian, Jun Zhou, Jiang-Miao Hu (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 13, 2018 Category: Drugs & Pharmacology Source Type: research

Hyperglycemia Promotes Chemoresistance Through the Reduction of the Mitochondrial DNA Damage, the Bax/Bcl-2 and Bax/Bcl-XL Ratio, and the Cells in Sub-G1 Phase Due to Antitumoral Drugs Induced-Cytotoxicity in Human Colon Adenocarcinoma Cells
Loredana Bergandi, Eleonora Mungo, Rosa Morone, Ornella Bosco, Barbara Rolando, Sophie Doublier (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 13, 2018 Category: Drugs & Pharmacology Source Type: research

Comparative Diminution of Patulin Content in Apple Juice With Food-Grade Additives Sodium Bicarbonate, Vinegar, Mixture of Sodium Bicarbonate and Vinegar, Citric Acid, Baking Powder, and Ultraviolet Irradiation
Minkyeong Kim, Shruti Shukla, Youngsook Oh, Soo Hyun Chung, Myunghee Kim (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 13, 2018 Category: Drugs & Pharmacology Source Type: research

Cannabidiol (CBD) Is a Novel Inhibitor for Exosome and Microvesicle (EMV) Release in Cancer
Uchini S. Kosgodage, Rhys Mould, Aine B. Henley, Alistair V. Nunn, Geoffrey W. Guy, E. L. Thomas, Jameel M. Inal, Jimmy D. Bell, Sigrun Lange (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 13, 2018 Category: Drugs & Pharmacology Source Type: research

Bone Protective Effects of Danggui Buxue Tang Alone and in Combination With Tamoxifen or Raloxifene in vivo and in vitro
Li-Ping Zhou, Ka-Ying Wong, Hoi-Ting Yeung, Xiao-Li Dong, Hui-Hui Xiao, Amy G.-W. Gong, Karl W.-K. Tsim, Man-Sau Wong (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 13, 2018 Category: Drugs & Pharmacology Source Type: research

Enhancement of Silymarin Anti-fibrotic Effects by Complexation With Hydroxypropyl (HPBCD) and Randomly Methylated (RAMEB) β-Cyclodextrins in a Mouse Model of Liver Fibrosis
Sami Gharbia, Cornel Balta, Hildegard Herman, Marcel Rosu, Judit V áradi, Ildikó Bácskay, Miklós Vecsernyés, Szilvia Gyöngyösi, Ferenc Fenyvesi, Sorina N. Voicu, Miruna S. Stan, Roxana E. Cristian, Anca Dinischiotu, Anca Hermenean (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 13, 2018 Category: Drugs & Pharmacology Source Type: research

Wogonin Attenuates Isoprenaline-Induced Myocardial Hypertrophy in Mice by Suppressing the PI3K/Akt Pathway
Weichun Qian, Dongsheng Yu, Jia Zhang, Qiaoyun Hu, Chuanfeng Tang, Peiyu Liu, Peng Ye, Xiaoli Wang, Qiu Lv, Minglong Chen, Liang Sheng (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 13, 2018 Category: Drugs & Pharmacology Source Type: research

Pharmacokinetics of Mycophenolate Mofetil and Development of Limited Sampling Strategy in Early Kidney Transplant Recipients
Jun Zhang, Zhi Sun, Zhenfeng Zhu, Jing Yang, Jian Kang, Guiwen Feng, Lin Zhou, Lihua Zuo, Yonggang Luo, Xiaojian Zhang (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 13, 2018 Category: Drugs & Pharmacology Source Type: research

Ulinastatin Ameliorates Pulmonary Capillary Endothelial Permeability Induced by Sepsis Through Protection of Tight Junctions via Inhibition of TNF- α and Related Pathways
Ming Fang, Wen-hong Zhong, Wen-liang Song, Yi-yu Deng, Duo-meng Yang, Bin Xiong, Hong-ke Zeng, Hua-dong Wang (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 13, 2018 Category: Drugs & Pharmacology Source Type: research

Optimizing Electrode Montages of Transcranial Direct Current Stimulation for Attentional Bias Modification in Early Abstinent Methamphetamine Users
Alireza Shahbabaie, Javad Hatami, Ali Farhoudian, Hamed Ekhtiari, Ali Khatibi, Michael A. Nitsche (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 10, 2018 Category: Drugs & Pharmacology Source Type: research

New Insights in Cardiac β-Adrenergic Signaling During Heart Failure and Aging
Claudio de Lucia, Akito Eguchi, Walter J. Koch (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 10, 2018 Category: Drugs & Pharmacology Source Type: research

miR-374a Regulates Inflammatory Response in Diabetic Nephropathy by Targeting MCP-1 Expression
Zijun Yang, Zuishuang Guo, Ji Dong, Shifeng Sheng, Yulin Wang, Lu Yu, Hongru Wang, Lin Tang (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 10, 2018 Category: Drugs & Pharmacology Source Type: research

Triphenyltin Chloride Delays Leydig Cell Maturation During Puberty in Rats
Linchao Li, Lubin Xie, Leikai Ma, Yong Chen, Xianwu Chen, Fei Ge, Tongliang Huang, Lanlan Chen, Tingting Hong, Xiaofang Chen, Qiqi Zhu, Xingwang Li, Ren-Shan Ge (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 10, 2018 Category: Drugs & Pharmacology Source Type: research

Investigating the Molecular Mechanism of Aqueous Extract of Cyclocarya paliurus on Ameliorating Diabetes by Transcriptome Profiling
Jing Li, Mei Luo, Minghua Hu, An-Yuan Guo, Xiangliang Yang, Qiong Zhang, Yanhong Zhu (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 9, 2018 Category: Drugs & Pharmacology Source Type: research

Sulodexide for Secondary Prevention of Recurrent Venous Thromboembolism: A Systematic Review and Meta-Analysis
Qing-Jun Jiang, Jun Bai, Jie Jin, Jian Shi, Lefeng Qu (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 8, 2018 Category: Drugs & Pharmacology Source Type: research

Role of Keap1-Nrf2 Signaling in Anhedonia Symptoms in a Rat Model of Chronic Neuropathic Pain: Improvement With Sulforaphane
Shan Li, Chun Yang, Xi Fang, Gaofeng Zhan, Niannian Huang, Jie Gao, Hui Xu, Kenji Hashimoto, Ailin Luo (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 8, 2018 Category: Drugs & Pharmacology Source Type: research

LncRNA-AK012226 Is Involved in Fat Accumulation in db/db Mice Fatty Liver and Non-alcoholic Fatty Liver Disease Cell Model
Xingtian Chen, Yangzhi Xu, Dan Zhao, Ting Chen, Chengxin Gu, Ganxiang Yu, Ken Chen, Yun Zhong, Jie He, Shiming Liu, Yuqiang Nie, Hui Yang (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 8, 2018 Category: Drugs & Pharmacology Source Type: research

Rapamycin Upregulates Connective Tissue Growth Factor Expression in Hepatic Progenitor Cells Through TGF- β-Smad2 Dependent Signaling
Yu Wu, Wei Wang, Xiang-mei Peng, Yi He, Yi-xiao Xiong, Hui-fang Liang, Liang Chu, Bi-xiang Zhang, Ze-yang Ding, Xiao-ping Chen (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 8, 2018 Category: Drugs & Pharmacology Source Type: research

Pharmacological Inhibition of Fatty Acid-Binding Protein 4 (FABP4) Protects Against Rhabdomyolysis-Induced Acute Kidney Injury
Rongshuang Huang, Min Shi, Fan Guo, Yuying Feng, Yanhuan Feng, Jing Liu, Lingzhi Li, Yan Liang, Jin Xiang, Song Lei, Liang Ma, Ping Fu (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 8, 2018 Category: Drugs & Pharmacology Source Type: research

Lobeglitazone Attenuates Airway Inflammation and Mucus Hypersecretion in a Murine Model of Ovalbumin-Induced Asthma
Na-Rae Shin, Sung-Hyeuk Park, Je-Won Ko, Young-Kwon Cho, In-Chul Lee, Jong-Choon Kim, In-Sik Shin, Joong-Sun Kim (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 8, 2018 Category: Drugs & Pharmacology Source Type: research

Lycorine Displays Potent Antitumor Efficacy in Colon Carcinoma by Targeting STAT3
Song Wu, Yuling Qiu, Yingying Shao, Shuangshuang Yin, Rui Wang, Xu Pang, Junhong Ma, Chunze Zhang, Bo Wu, Sangho Koo, Lifeng Han, Yi Zhang, Xiumei Gao, Tao Wang, Haiyang Yu (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 8, 2018 Category: Drugs & Pharmacology Source Type: research

Predicting Structural Details of the Sodium Channel Pore Basing on Animal Toxin Studies
Denis B. Tikhonov, Boris S. Zhorov (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 7, 2018 Category: Drugs & Pharmacology Source Type: research

Anion-Transport Mechanism of a Triazole-Bearing Derivative of Prodigiosine: A Candidate for Cystic Fibrosis Therapy
Claudia Cossu, Michele Fiore, Debora Baroni, Valeria Capurro, Emanuela Caci, Maria Garcia-Valverde, Roberto Quesada, Oscar Moran (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 7, 2018 Category: Drugs & Pharmacology Source Type: research

Acarbose Use and Liver Injury in Diabetic Patients With Severe Renal Insufficiency and Hepatic Diseases: A Propensity Score-Matched Cohort Study
Chia-Ter Chao, Jui Wang, Jenq-Wen Huang, Kuo-Liong Chien (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 7, 2018 Category: Drugs & Pharmacology Source Type: research

Association of Variability and Pharmacogenomics With Bioequivalence of Gefitinib in Healthy Male Subjects
Hong Zhang, Qingmei Li, Xiaoxue Zhu, Min Wu, Cuiyun Li, Xiaojiao Li, Chengjiao Liu, Zhenwei Shen, Yanhua Ding, Shucheng Hua (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 7, 2018 Category: Drugs & Pharmacology Source Type: research

Detecting Pharmacovigilance Signals Combining Electronic Medical Records With Spontaneous Reports: A Case Study of Conventional Disease-Modifying Antirheumatic Drugs for Rheumatoid Arthritis
Liwei Wang, Majid Rastegar-Mojarad, Zhiliang Ji, Sijia Liu, Ke Liu, Sungrim Moon, Feichen Shen, Yanshan Wang, Lixia Yao, John M. Davis III, Hongfang Liu (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 7, 2018 Category: Drugs & Pharmacology Source Type: research

EphB2 Deficiency Induces Depression-Like Behaviors and Memory Impairment: Involvement of NMDA 2B Receptor Dependent Signaling
Linlin Zhen, Tuo Shao, Victor Luria, Gaowen Li, Zhi Li, Ying Xu, Xin Zhao (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 7, 2018 Category: Drugs & Pharmacology Source Type: research

The WT1/MVP-Mediated Stabilization on mTOR/AKT Axis Enhances the Effects of Cisplatin in Non-small Cell Lung Cancer by a Reformulated Yu Ping Feng San Herbal Preparation
Jian-Shu Lou, Yi-Teng Xia, Huai-You Wang, Xiang-Peng Kong, Ping Yao, Tina T. X. Dong, Zhong-Yu Zhou, Karl W. K. Tsim (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 7, 2018 Category: Drugs & Pharmacology Source Type: research

Clinical Significance of Organic Anion Transporting Polypeptide Gene Expression in High-Grade Serous Ovarian Cancer
Martin Svoboda, Felicitas Mungenast, Andreas Gleiss, Ignace Vergote, Adriaan Vanderstichele, Jalid Sehouli, Elena Braicu, Sven Mahner, Walter J äger, Diana Mechtcheriakova, Dan Cacsire-Tong, Robert Zeillinger, Theresia Thalhammer, Dietmar Pils (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 7, 2018 Category: Drugs & Pharmacology Source Type: research