Anticancer Therapy-Induced Atrial Fibrillation: Electrophysiology and Related Mechanisms
Xinyu Yang, Xinye Li, Mengchen Yuan, Chao Tian, Yihan Yang, Xiaofeng Wang, Xiaoyu Zhang, Yang Sun, Tianmai He, Songjie Han, Guang Chen, Nian Liu, Yonghong Gao, Dan Hu, Yanwei Xing, Hongcai Shang (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 16, 2018 Category: Drugs & Pharmacology Source Type: research

Palliative Care: Taking the Long View
Mar ía Teresa García-Baquero Merino (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 16, 2018 Category: Drugs & Pharmacology Source Type: research

Antioxidant and Oxidative Stress: A Mutual Interplay in Age-Related Diseases
Bee Ling Tan, Mohd Esa Norhaizan, Winnie-Pui-Pui Liew, Heshu Sulaiman Rahman (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 16, 2018 Category: Drugs & Pharmacology Source Type: research

Joint Task Force for Clinical Trial Competency and Clinical Research Professional Workforce Development
Stephen A. Sonstein, Carolynn T. Jones (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 16, 2018 Category: Drugs & Pharmacology Source Type: research

Essential Role of Keap1-Nrf2 Signaling in Mood Disorders: Overview and Future Perspective
Kenji Hashimoto (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 16, 2018 Category: Drugs & Pharmacology Source Type: research

Discovery of a Novel Nav1.7 Inhibitor From Cyriopagopus albostriatus Venom With Potent Analgesic Efficacy
Yunxiao Zhang, Dezheng Peng, Biao Huang, Qiuchu Yang, Qingfeng Zhang, Minzhi Chen, Mingqiang Rong, Zhonghua Liu (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 16, 2018 Category: Drugs & Pharmacology Source Type: research

Chromatin Regulation by HP1 γ Contributes to Survival of 5-Azacytidine-Resistant Cells
Satoshi Imanishi, Tomohiro Umezu, Chiaki Kobayashi, Tomohiko Ohta, Kazuma Ohyashiki, Junko H. Ohyashiki (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 16, 2018 Category: Drugs & Pharmacology Source Type: research

Chemical Profiling and Comparison of Sangju Ganmao Tablet and Its Component Herbs Using Two-Dimensional Liquid Chromatography to Explore Compatibility Mechanism of Herbs
Shuai Ji, Zhan-Zhong Liu, Jing Wu, Yan Du, Zhen-Yu Su, Tian-Yun Wang, Jie Han, Dong-Zhi Yang, Meng-Zhe Guo, Dao-Quan Tang (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 16, 2018 Category: Drugs & Pharmacology Source Type: research

Promising Antineoplastic Actions of Melatonin
Gaia Favero, Enrico Moretti, Francesca Bonomini, Russel J. Reiter, Luigi Fabrizio Rodella, Rita Rezzani (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 16, 2018 Category: Drugs & Pharmacology Source Type: research

Economic Evaluation of Combination Therapy Versus Monotherapy for Treatment of Benign Prostatic Hyperplasia in Hong Kong
David Bin-Chia Wu, Chi Hang Yee, Chi-Fai Ng, Shaun Wen Huey Lee, Nathorn Chaiyakunapruk, Yu-Shan Chang, Kenneth Kwing Chin Lee (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 16, 2018 Category: Drugs & Pharmacology Source Type: research

Potentiation of Glutamatergic Synaptic Transmission Onto Dorsal Raphe Serotonergic Neurons in the Valproic Acid Model of Autism
Ruixiang Wang, Kathryn Hausknecht, Roh-Yu Shen, Samir Haj-Dahmane (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 16, 2018 Category: Drugs & Pharmacology Source Type: research

Icariin Ameliorates Palmitate-Induced Insulin Resistance Through Reducing Thioredoxin-Interacting Protein (TXNIP) and Suppressing ER Stress in C2C12 Myotubes
Mingxin Li, Yemin Zhang, Yingkang Cao, Deling Zhang, Le Liu, Yanghongyun Guo, Changhua Wang (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 16, 2018 Category: Drugs & Pharmacology Source Type: research

Zebrafish Larvae Are a Suitable Model to Investigate the Metabolic Phenotype of Drug-Induced Renal Tubular Injury
Judit Morello, Rico J. E. Derks, Susana S. Lopes, Evelyne Steenvoorden, Emilia C. Monteiro, Oleg A. Mayboroda, Sofia A. Pereira (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 16, 2018 Category: Drugs & Pharmacology Source Type: research

GLP-1 Improves Adipocyte Insulin Sensitivity Following Induction of Endoplasmic Reticulum Stress
Yaojing Jiang, Zhihong Wang, Bo Ma, Linling Fan, Na Yi, Bin Lu, Qinghua Wang, Rui Liu (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 16, 2018 Category: Drugs & Pharmacology Source Type: research

HBK-17, a 5-HT1A Receptor Ligand With Anxiolytic-Like Activity, Preferentially Activates ß-Arrestin Signaling
Karolina Pytka, Monika G łuch-Lutwin, Elżbieta Żmudzka, Kinga Sałaciak, Agata Siwek, Katarzyna Niemczyk, Maria Walczak, Magdalena Smolik, Adrian Olczyk, Adam Gałuszka, Jarosław Śmieja, Barbara Filipek, Jacek Sapa, Marcin Kołaczkowski, Katarzyna Pańczyk, Anna Waszkielewicz, Henryk Marona (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 16, 2018 Category: Drugs & Pharmacology Source Type: research

Cerium Oxide Nanoparticles Re-establish Cell Integrity Checkpoints and Apoptosis Competence in Irradiated HaCat Cells via Novel Redox-Independent Activity
Fanny Caputo, Anna Giovanetti, Francesca Corsi, Vittoria Maresca, Stefania Briganti, Silvia Licoccia, Enrico Traversa, Lina Ghibelli (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 16, 2018 Category: Drugs & Pharmacology Source Type: research

The Microbiome: A New Target for Research and Treatment of Schizophrenia and its Resistant Presentations? A Systematic Literature Search and Review
Alessandro Cuomo, Giuseppe Maina, Gianluca Rosso, Bruno Beccarini Crescenzi, Simone Bolognesi, Angela Di Muro, Nicola Giordano, Arianna Goracci, Stephen M. Neal, Maria Nitti, Fulvio Pieraccini, Andrea Fagiolini (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 15, 2018 Category: Drugs & Pharmacology Source Type: research

Reconstituted HDL: Drug Delivery Platform for Overcoming Biological Barriers to Cancer Therapy
Sangram Raut, Linda Mooberry, Nirupama Sabnis, Ashwini Garud, Akpedje Serena Dossou, Andras Lacko (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 15, 2018 Category: Drugs & Pharmacology Source Type: research

Analgesic Activity, Chemical Profiling and Computational Study on Chrysopogon aciculatus
S. M. Neamul Kabir Zihad, Niloy Bhowmick, Shaikh Jamal Uddin, Nazifa Sifat, Md. Shamim Rahman, Razina Rouf, Muhammad Torequl Islam, Shrabanti Dev, Hazrina Hazni, Shahin Aziz, Eun üs S. Ali, Asish K. Das, Jamil A. Shilpi, Lutfun Nahar, Satyajit D. Sarker (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 15, 2018 Category: Drugs & Pharmacology Source Type: research

Changes in Membrane Protein Clustering in Peripheral Lymphocytes in an Animal Model of Depression Parallel Those Observed in Na ïve Depression Patients: Implications for the Development of Novel Biomarkers of Depression
Raquel Romay-Tallon, Erin Kulhawy, Kyle J. Brymer, Josh Allen, Tania Rivera-Baltanas, Jose M. Olivares, Lisa E. Kalynchuk, Hector J. Caruncho (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 15, 2018 Category: Drugs & Pharmacology Source Type: research

Novobiocin, a Newly Found TRPV1 Inhibitor, Attenuates the Expression of TRPV1 in Rat Intestine and Intestinal Epithelial Cell Line IEC-6
Qianying Liang, Xueli Lv, Qing Cai, Yun Cai, Boxin Zhao, Guofeng Li (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 15, 2018 Category: Drugs & Pharmacology Source Type: research

Prediction of Potential Small Molecule-Associated MicroRNAs Using Graphlet Interaction
Na-Na Guan, Ya-Zhou Sun, Zhong Ming, Jian-Qiang Li, Xing Chen (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 15, 2018 Category: Drugs & Pharmacology Source Type: research

P311, Friend, or Foe of Tissue Fibrosis?
Leslie Stradiot, Inge Mannaerts, Leo A. van Grunsven (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 12, 2018 Category: Drugs & Pharmacology Source Type: research

Comparison of Zidovudine and Tenofovir Based Regimens With Regard to Health-Related Quality of Life and Prevalence of Symptoms in HIV Patients in a Kenyan Referral Hospital
Jilian O. Etenyi, Faith A. Okalebo, Margaret Oluka, Kipruto A. Sinei, George O. Osanjo, Amanj Kurdi, Johanna C. Meyer, Brian Godman, Sylvia Opanga (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 12, 2018 Category: Drugs & Pharmacology Source Type: research

Simulated Microgravity Altered the Metabolism of Loureirin B and the Expression of Major Cytochrome P450 in Liver of Rats
Bo Chen, Jingjing Guo, Shibo Wang, Liting Kang, Yulin Deng, Yujuan Li (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 12, 2018 Category: Drugs & Pharmacology Source Type: research

The Extent and Reasons for Dissatisfaction From Outpatients Provided With Pharmacy Services at Two Public Hospitals in Eastern Ethiopia
Shambel Nigussie, Dumessa Edessa (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 12, 2018 Category: Drugs & Pharmacology Source Type: research

Genistein Ameliorates Scopolamine-Induced Amnesia in Mice Through the Regulation of the Cholinergic Neurotransmission, Antioxidant System and the ERK/CREB/BDNF Signaling
Cong Lu, Yan Wang, Teng Xu, Qi Li, Donghui Wang, Lijing Zhang, Bei Fan, Fengzhong Wang, Xinmin Liu (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 12, 2018 Category: Drugs & Pharmacology Source Type: research

Metabolic Characterization of Antifolate Responsiveness and Non-responsiveness in Malignant Pleural Mesothelioma Cells
Yuzo Sato, Shiori Matsuda, Ami Maruyama, Joji Nakayama, Tomoyuki Miyashita, Hibiki Udagawa, Shigeki Umemura, Kazuyoshi Yanagihara, Atsushi Ochiai, Masaru Tomita, Tomoyoshi Soga, Katsuya Tsuchihara, Hideki Makinoshima (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 12, 2018 Category: Drugs & Pharmacology Source Type: research

A Cell Model Suitable for a High-Throughput Screening of Inhibitors of the Wnt/ β-Catenin Pathway
Marina Grimaldi, Abdelhay Boulahtouf, Corinne Pr évostel, Alain Thierry, Patrick Balaguer, Philippe Blache (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 11, 2018 Category: Drugs & Pharmacology Source Type: research

Teriflunomide Is an Indirect Human Constitutive Androstane Receptor (CAR) Activator Interacting With Epidermal Growth Factor (EGF) Signaling
Alejandro Carazo, Jan Dusek, Ondrej Holas, Josef Skoda, Lucie Hyrsova, Tomas Smutny, Tomas Soukup, Martin Dosedel, Petr P ávek (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 11, 2018 Category: Drugs & Pharmacology Source Type: research

Application of ITC-Based Characterization of Thermodynamic and Kinetic Association of Ligands With Proteins in Drug Design
Haixia Su, Yechun Xu (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 11, 2018 Category: Drugs & Pharmacology Source Type: research

Drug Interactions With New Synthetic Opioids
Clara P érez-Mañá, Esther Papaseit, Francina Fonseca, Adriana Farré, Marta Torrens, Magi Farré (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 11, 2018 Category: Drugs & Pharmacology Source Type: research

Calcium Sensing Receptor-Related Pathway Contributes to Cardiac Injury and the Mechanism of Astragaloside IV on Cardioprotection
Meili Lu, Bin Leng, Xin He, Zhen Zhang, Hongxin Wang, Futian Tang (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 11, 2018 Category: Drugs & Pharmacology Source Type: research

Development of an Infrastructure for the Prediction of Biological Endpoints in Industrial Environments. Lessons Learned at the eTOX Project
Manuel Pastor, Jordi Quintana, Ferran Sanz (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 11, 2018 Category: Drugs & Pharmacology Source Type: research

Interference With Coagulation Cascade as a Novel Approach to Counteract Cisplatin-Induced Acute Tubular Necrosis; an Experimental Study in Rats
Mohamed G. Ewees, Basim A. S. Messiha, Ali A. Abo-Saif, Asmaa M. A. Bayoumi, Mohamed S. Abdel-Bakky (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 11, 2018 Category: Drugs & Pharmacology Source Type: research

A cell model suitable for a high-throughput screening of inhibitors of the Wnt/ β-catenin pathway.
Marina Grimaldi, Abdelhay Boulahtouf, Corinne Pr évostel, Alain R THIERRY, Patrick Balaguer, Philippe Blache (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 11, 2018 Category: Drugs & Pharmacology Source Type: research

Sofosbuvir: A Potential Treatment for Ebola
Sandra E. Reznik, Amit K. Tiwari, Charles R. Ashby (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 10, 2018 Category: Drugs & Pharmacology Source Type: research

Comparison of Quantitative and Qualitative (Q)SAR Models Created for the Prediction of Ki and IC50 Values of Antitarget Inhibitors
Alexey A. Lagunin, Maria A. Romanova, Anton D. Zadorozhny, Natalia S. Kurilenko, Boris V. Shilov, Pavel V. Pogodin, Sergey M. Ivanov, Dmitry A. Filimonov, Vladimir V. Poroikov (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 10, 2018 Category: Drugs & Pharmacology Source Type: research

Siddha Medicine in Eastern Sri Lanka Today –Continuity and Change in the Treatment of Diabetes
Saravanan V. Sathasivampillai, Pholtan R. S. Rajamanoharan, Michael Heinrich (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 10, 2018 Category: Drugs & Pharmacology Source Type: research

Inhibitors of DNA Methyltransferases From Natural Sources: A Computational Perspective
Fernanda I. Sald ívar-González, Alejandro Gómez-García, David E. Chávez-Ponce de León, Norberto Sánchez-Cruz, Javier Ruiz-Rios, B. Angélica Pilón-Jiménez, José L. Medina-Franco (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 10, 2018 Category: Drugs & Pharmacology Source Type: research

Burst-Like Subcutaneous Electrical Stimulation Induces BDNF-Mediated, Cyclotraxin B-Sensitive Central Sensitization in Rat Spinal Cord
Jeffri Retamal, Andrea Reyes, Paulina Ramirez, David Bravo, Alejandro Hernandez, Teresa Pelissier, Luis Villanueva, Luis Constandil (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 10, 2018 Category: Drugs & Pharmacology Source Type: research

Population Pharmacokinetic Study of Cefazolin Used Prophylactically in Canine Surgery for Susceptibility Testing Breakpoint Determination
Petra Cagnardi, Federica Di Cesare, Pierre-Louis Toutain, Alain Bousquet-M élou, Giuliano Ravasio, Roberto Villa (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 9, 2018 Category: Drugs & Pharmacology Source Type: research

Phytohormone Abscisic Acid Improves Spatial Memory and Synaptogenesis Involving NDR1/2 Kinase in Rats
Juanjuan Liu, Xiaozhen Gu, Rongxin Zou, Wenping Nan, Shaohua Yang, Hui-Li Wang, Xiang-Tao Chen (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 9, 2018 Category: Drugs & Pharmacology Source Type: research

Corrigendum: Ulinastatin Inhibits Osteoclastogenesis and Suppresses Ovariectomy-Induced Bone Loss by Downregulating uPAR
Jun-ming Huang, Ran-yue Ren, Yuan Bao, Jia-chao Guo, Wei Xiang, Xing-zhi Jing, Jia Shi, Guo-xiang Zhang, Long Li, Yong Tian, Hao Kang, Feng-jin Guo (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 9, 2018 Category: Drugs & Pharmacology Source Type: research

Network-Based Methods for Prediction of Drug-Target Interactions
Zengrui Wu, Weihua Li, Guixia Liu, Yun Tang (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 9, 2018 Category: Drugs & Pharmacology Source Type: research

Development and Validation of a Novel General Medication Adherence Scale (GMAS) for Chronic Illness Patients in Pakistan
Atta Abbas Naqvi, Mohamed Azmi Hassali, Mehwish Rizvi, Ale Zehra, Wajiha Iffat, Abdul Haseeb, Shazia Jamshed (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 9, 2018 Category: Drugs & Pharmacology Source Type: research

17 β-Estradiol Enhances Schwann Cell Differentiation via the ERβ-ERK1/2 Signaling Pathway and Promotes Remyelination in Injured Sciatic Nerves
Yun Gu, Yumen Wu, Wenfeng Su, LingYan Xing, Yuntian Shen, Xiaowen He, Lilan Li, Ying Yuan, Xin Tang, Gang Chen (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 9, 2018 Category: Drugs & Pharmacology Source Type: research

Development of a Conjunctivitis Outpatient Rate Prediction Model Incorporating Ambient Ozone and Meteorological Factors in South Korea
Jeong-Won Seo, Jong-Sang Youn, SeJoon Park, Choun-Ki Joo (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 9, 2018 Category: Drugs & Pharmacology Source Type: research

Olmutinib (BI1482694/HM61713), a Novel Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, Reverses ABCG2-Mediated Multidrug Resistance in Cancer Cells
Wei Zhang, Ying-Fang Fan, Chao-Yun Cai, Jing-Quan Wang, Qiu-Xu Teng, Zi-Ning Lei, Leli Zeng, Pranav Gupta, Zhe-Sheng Chen (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 9, 2018 Category: Drugs & Pharmacology Source Type: research

Ulinastatin May Significantly Improve Postoperative Cognitive Function of Elderly Patients Undergoing Spinal Surgery by Reducing the Translocation of Lipopolysaccharide and Systemic Inflammation
Min Zhang, Yan-Hua Zhang, Hui-Qun Fu, Qing-Ming Zhang, Tian-Long Wang (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 9, 2018 Category: Drugs & Pharmacology Source Type: research