Acute Iloprost Inhalation Improves Right Ventricle Function in Pulmonary Artery Hypertension: A Cardiac Magnetic Resonance Study
Jing-Hui Li, Hong-Da Zhang, Zhen-Zhen Wang, Qing-Qing Lu, Dong Li, Tian-Yu Lian, Zi-Chao Lv, Xin Jiang, Yan Wu, Jue Ye, Shihua Zhao, Zhenwen Yang (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 21, 2019 Category: Drugs & Pharmacology Source Type: research

Protective Effects of Live Combined B. subtilis and E. faecium in Polymicrobial Sepsis Through Modulating Activation and Transformation of Macrophages and Mast Cells
Lisha Guo, Mei Meng, Yaping Wei, Feixue Lin, Ying Jiang, Xianzhen Cui, Guirong Wang, Chunting Wang, Xiaosun Guo (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 21, 2019 Category: Drugs & Pharmacology Source Type: research

The Distinct Effects of Palmitic and Oleic Acid on Pancreatic Beta Cell Function: The Elucidation of Associated Mechanisms and Effector Molecules
Miruna Nemecz, Alina Constantin, Madalina Dumitrescu, Nicoleta Alexandru, Alexandru Filippi, Gabriela Tanko, Adriana Georgescu (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 21, 2019 Category: Drugs & Pharmacology Source Type: research

Lymphoid Interstitial Pneumonia in Common Variable Immune Deficiency – Case Report With Disease Monitoring in Various Therapeutic Options: Pleiotropic Effects of Rituximab Regimens
Przemyslaw Zdziarski, Andrzej Gamian (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 18, 2019 Category: Drugs & Pharmacology Source Type: research

20(S)-Protopanaxadiol Inhibits Titanium Particle-Induced Inflammatory Osteolysis and RANKL-Mediated Osteoclastogenesis via MAPK and NF- κB Signaling Pathways
Chenhao Pan, Haojie Shan, Tianyi Wu, Wei Liu, Yiwei Lin, Wenyang Xia, Feng Wang, Zubin Zhou, Xiaowei Yu (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 18, 2019 Category: Drugs & Pharmacology Source Type: research

Mechanism of Beraprost Effects on Pulmonary Hypertension: Contribution of Cross-Binding to PGE2 Receptor 4 and Modulation of O2 Sensitive Voltage-Gated K+ Channels
Fenling Fan, Hua Tian, Jie Geng, Jizhao Deng, Ya Liu, Chunyan Chen, Songlin Zhang, Yushun Zhang, Jie Li, Hongyan Tian, Anthony M. Dart, Yuliang Zou (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 18, 2019 Category: Drugs & Pharmacology Source Type: research

Integration of Metabolomics and Transcriptomics Reveals the Therapeutic Mechanism Underlying Paeoniflorin for the Treatment of Allergic Asthma
Qiyang Shou, Lu Jin, Jiali Lang, Qiyuan Shan, Zhunan Ni, Changpei Cheng, Qinglin Li, Huiying Fu, Gang Cao (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 18, 2019 Category: Drugs & Pharmacology Source Type: research

Galenic Preparations of Therapeutic Cannabis sativa Differ in Cannabinoids Concentration: A Quantitative Analysis of Variability and Possible Clinical Implications
Alessandra Bettiol, Niccol ò Lombardi, Giada Crescioli, Valentina Maggini, Eugenia Gallo, Alessandro Mugelli, Fabio Firenzuoli, Roberto Baronti, Alfredo Vannacci (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 17, 2019 Category: Drugs & Pharmacology Source Type: research

The Protectin Family of Specialized Pro-resolving Mediators: Potent Immunoresolvents Enabling Innovative Approaches to Target Obesity and Diabetes
Trond Vidar Hansen, Anders Vik, Charles N. Serhan (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 17, 2019 Category: Drugs & Pharmacology Source Type: research

Treatment With a Flavonoid-Rich Fraction of Bergamot Juice Improved Lipopolysaccharide-Induced Periodontitis in Rats
Enrico Gugliandolo, Roberta Fusco, Ramona D ’Amico, Matteo Peditto, Giacomo Oteri, Rosanna Di Paola, Salvatore Cuzzocrea, Michele Navarra (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 17, 2019 Category: Drugs & Pharmacology Source Type: research

Aflatoxin B1 Degradation and Detoxification by Escherichia coli CG1061 Isolated From Chicken Cecum
Lingling Wang, Jun Wu, Zhiwen Liu, Yutao Shi, Jinqiu Liu, Xiaofan Xu, Shuxian Hao, Peiqiang Mu, Fengru Deng, Yiqun Deng (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 17, 2019 Category: Drugs & Pharmacology Source Type: research

Sortilin in Glucose Homeostasis: From Accessory Protein to Key Player?
Nicolas Blondeau, Sophie B éraud-Dufour, Patricia Lebrun, Céline Hivelin, Thierry Coppola (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 15, 2019 Category: Drugs & Pharmacology Source Type: research

The Management of Heavy Menstrual Bleeding After Percutaneous Coronary Intervention in a Woman of Reproductive Age
Zhi-Chun Gu, Fang-Hong Shi, Jie Zhu, Fang Wan, Long Shen, Hao Li (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 15, 2019 Category: Drugs & Pharmacology Source Type: research

Role of Vonoprazan in Helicobacter pylori Eradication Therapy in Japan
Mitsushige Sugimoto, Yoshio Yamaoka (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 15, 2019 Category: Drugs & Pharmacology Source Type: research

Three Novel ACE Inhibitory Peptides Isolated From Ginkgo biloba Seeds: Purification, Inhibitory Kinetic and Mechanism
Fei-Fei Ma, Hao Wang, Chao-Kun Wei, Kiran Thakur, Zhao-Jun Wei, Li Jiang (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 15, 2019 Category: Drugs & Pharmacology Source Type: research

Potential Nexus of Non-alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus: Insulin Resistance Between Hepatic and Peripheral Tissues
Wan Mu, Xue-fang Cheng, Ying Liu, Qian-zhou Lv, Gao-lin Liu, Ji-gang Zhang, Xiao-yu Li (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 14, 2019 Category: Drugs & Pharmacology Source Type: research

Deficiency of Soluble Epoxide Hydrolase Protects Cardiac Function Impaired by LPS-Induced Acute Inflammation
Victor Samokhvalov, K. Lockhart Jamieson, Ahmed M. Darwesh, Hedieh Keshavarz-Bahaghighat, Tim Y. T. Lee, Matthew Edin, Fred Lih, Darryl C. Zeldin, John M. Seubert (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 14, 2019 Category: Drugs & Pharmacology Source Type: research

High Throughput mRNA Sequencing Reveals Potential Therapeutic Targets of Tao-Hong-Si-Wu Decoction in Experimental Middle Cerebral Artery Occlusion
Xianchun Duan, Lan Han, Daiyin Peng, Weidong Chen, Can Peng, Ling Xiao, Qiuyu Bao (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 14, 2019 Category: Drugs & Pharmacology Source Type: research

Probing the Role of Melanocortin Type 1 Receptor Agonists in Diverse Immunological Diseases
Carl Spana, Andrew W. Taylor, David G. Yee, Marie Makhlina, Wei Yang, John Dodd (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 14, 2019 Category: Drugs & Pharmacology Source Type: research

Contribution of Nrf2 Modulation to the Mechanism of Action of Analgesic and Anti-inflammatory Drugs in Pre-clinical and Clinical Stages
Larissa Staurengo-Ferrari, Stephanie Badaro-Garcia, Miriam S. N. Hohmann, Mar ília F. Manchope, Tiago H. Zaninelli, Rubia Casagrande, Waldiceu A. Verri (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 11, 2019 Category: Drugs & Pharmacology Source Type: research

Storax Protected Oxygen-Glucose Deprivation/Reoxygenation Induced Primary Astrocyte Injury by Inhibiting NF- κB Activation in vitro
Meng Zhang, Yan Ma, Lijuan Chai, Haoping Mao, Junhua Zhang, Xiang Fan (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 11, 2019 Category: Drugs & Pharmacology Source Type: research

Systems Pharmacology Dissection of Multi-Scale Mechanisms of Action of Huo-Xiang-Zheng-Qi Formula for the Treatment of Gastrointestinal Diseases
Miaoqing Zhao, Yangyang Chen, Chao Wang, Wei Xiao, Shusheng Chen, Shuwei Zhang, Ling Yang, Yan Li (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 11, 2019 Category: Drugs & Pharmacology Source Type: research

Factors Associated With Response and Resistance to Cognitive Remediation in Schizophrenia: A Critical Review
Stefano Barlati, Giacomo Deste, Alessandro Galluzzo, Anna Paola Perin, Paolo Valsecchi, Cesare Turrina, Antonio Vita (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 10, 2019 Category: Drugs & Pharmacology Source Type: research

Inhibition of Soluble Epoxide Hydrolase for Renal Health
Jun-Yan Liu (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 10, 2019 Category: Drugs & Pharmacology Source Type: research

Microbial-Based Therapies in the Treatment of Inflammatory Bowel Disease – An Overview of Human Studies
Paulo Jos é Basso, Niels Olsen Saraiva Câmara, Helioswilton Sales-Campos (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 10, 2019 Category: Drugs & Pharmacology Source Type: research

Y6, an Epigallocatechin Gallate Derivative, Reverses ABCG2-Mediated Mitoxantrone Resistance
Rui-Qiang Zhao, Yan Wen, Pranav Gupta, Zi-Ning Lei, Chao-Yun Cai, Gang Liang, Dong-Hua Yang, Zhe-Sheng Chen, Yu-An Xie (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 10, 2019 Category: Drugs & Pharmacology Source Type: research

MicroRNA-181a Functions as an Oncogene in Gastric Cancer by Targeting Caprin-1
Qiang Lu, Yanchun Chen, Dan Sun, Shukun Wang, Kang Ding, Meiyi Liu, Yan Zhang, Yujuan Miao, Huancai Liu, Fenghua Zhou (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 10, 2019 Category: Drugs & Pharmacology Source Type: research

Is There a Threshold for Medication Adherence? Lessons Learnt From Electronic Monitoring of Drug Adherence
Michel Burnier (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 9, 2019 Category: Drugs & Pharmacology Source Type: research

A Novel Naphthoquinone-Coumarin Hybrid That Inhibits BCR-ABL1-STAT5 Oncogenic Pathway and Reduces Survival in Imatinib-Resistant Chronic Myelogenous Leukemia Cells
Patricia Mart ín-Rodríguez, Borja Guerra, Idaira Hueso-Falcón, Haidee Aranda-Tavío, Juan Díaz-Chico, José Quintana, Francisco Estévez, Bonifacio Díaz-Chico, Angel Amesty, Ana Estévez-Braun, Leandro Fernández-Pérez (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 9, 2019 Category: Drugs & Pharmacology Source Type: research

Contribution of Altered Endocannabinoid System to Overactive mTORC1 Signaling in Focal Cortical Dysplasia
Daniel Garc ía-Rincón, Javier Díaz-Alonso, Juan Paraíso-Luna, Zaira Ortega, José Aguareles, Adán de Salas-Quiroga, Cristina Jou, Inmaculada de Prada, Verónica Martínez-Cerdeño, Eleonora Aronica, Manuel Guzmán, María Ángeles Pérez-Jiménez, Ismael Galve-Roperh (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 9, 2019 Category: Drugs & Pharmacology Source Type: research

The Prognostic and Therapeutic Value of PD-L1 in Glioma
Ruo Qiao Chen, Feng Liu, Xin Yao Qiu, Xiao Qian Chen (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 9, 2019 Category: Drugs & Pharmacology Source Type: research

A Review of Resveratrol as a Potent Chemoprotective and Synergistic Agent in Cancer Chemotherapy
Qicai Xiao, Wangshu Zhu, Wei Feng, Su Seong Lee, Albert Wingnang Leung, Jun Shen, Liqian Gao, Chuanshan Xu (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 9, 2019 Category: Drugs & Pharmacology Source Type: research

Erythropoiesis-Stimulating Agents in the Management of Anemia in Chronic Kidney Disease or Cancer: A Historical Perspective
Matti Aapro, Pere Gasc ón, Kashyap Patel, George M. Rodgers, Selwyn Fung, Luiz H. Arantes, Jay Wish (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 9, 2019 Category: Drugs & Pharmacology Source Type: research

Phenotype-Driven Virtual Panel Is an Effective Method to Analyze WES Data of Neurological Disease
Xu Wang, Xiang Shen, Fang Fang, Chang-Hong Ding, Hao Zhang, Zhen-Hua Cao, Dong-Yan An (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 9, 2019 Category: Drugs & Pharmacology Source Type: research

Oral Cannabidiol Use in Children With Autism Spectrum Disorder to Treat Related Symptoms and Co-morbidities
Dana Barchel, Orit Stolar, Tal De-Haan, Tomer Ziv-Baran, Naama Saban, Danny Or Fuchs, Gideon Koren, Matitiahu Berkovitch (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 9, 2019 Category: Drugs & Pharmacology Source Type: research

Social Defeat Stress Decreases mRNA for Monoamine Oxidase A and Increases 5-HT Turnover in the Brain of Male Nile Tilapia (Oreochromis niloticus)
Yuki Higuchi, Tomoko Soga, Ishwar S. Parhar (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 9, 2019 Category: Drugs & Pharmacology Source Type: research

Antiplatelet and Antithrombotic Activity of a Traditional Medicine, Hwangryunhaedok-Tang
Kyungho Kim, Hyun Ju Do, Tae Woo Oh, Kwang-Youn Kim, Tae Hoon Kim, Jin Yel Ma, Kwang-Il Park (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 9, 2019 Category: Drugs & Pharmacology Source Type: research

Involvement of NMDA-AKT-mTOR Signaling in Rapid Antidepressant-Like Activity of Chaihu-jia-Longgu-Muli-tang on Olfactory Bulbectomized Mice
Xing Wang, Zhilu Zou, Qinqin Shen, Zhiheng Huang, Jie Chen, Juanjuan Tang, Wenda Xue, Weiwei Tao, Haoxin Wu, Dawei Wang, Gang Chen (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 9, 2019 Category: Drugs & Pharmacology Source Type: research

miR-26 Induces Apoptosis and Inhibits Autophagy in Non-small Cell Lung Cancer Cells by Suppressing TGF- β1-JNK Signaling Pathway
Yi He, Hao Liu, Lianyong Jiang, Bi Rui, Ju Mei, Haibo Xiao (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 9, 2019 Category: Drugs & Pharmacology Source Type: research

Niclosamide Induces Cell Cycle Arrest in G1 Phase in Head and Neck Squamous Cell Carcinoma Through Let-7d/CDC34 Axis
Zewen Han, Qingxiang Li, Yifei Wang, Lin Wang, Xiaoxu Li, Na Ge, Yixiang Wang, Chuanbin Guo (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 9, 2019 Category: Drugs & Pharmacology Source Type: research

Simultaneous Extraction and Determination of Compounds With Different Polarities From Platycladi Cacumen by AQ C18-Based Vortex-Homogenized Matrix Solid-Phase Dispersion With Ionic Liquid
Mingya Ding, Jin Li, Shuhan Zou, Ge Tang, Xiumei Gao, Yan-xu Chang (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 9, 2019 Category: Drugs & Pharmacology Source Type: research

A Cell-Based Metabonomics Approach to Investigate the Varied Influences of Chrysophanol-8-O- β-D-Glucoside With Different Concentrations on L-02 Cells
Meichen Liu, Xiaohong Gong, Yunyun Quan, Yimeng Zhou, Yunxia Li, Cheng Peng (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 9, 2019 Category: Drugs & Pharmacology Source Type: research

Zolpidem Activation of Alpha 1-Containing GABAA Receptors Selectively Inhibits High Frequency Action Potential Firing of Cortical Neurons
Elena Neumann, Uwe Rudolph, Daniel E. Knutson, Guanguan Li, James M. Cook, Harald Hentschke, Bernd Antkowiak, Berthold Drexler (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 9, 2019 Category: Drugs & Pharmacology Source Type: research

Mutations Defining Patient Cohorts With Elevated PD-L1 Expression in Gastric Cancer
Ot ília Menyhárt, Lőrinc Sándor Pongor, Balázs Győrffy (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 8, 2019 Category: Drugs & Pharmacology Source Type: research

Effect of Sodium-Glucose Co-transporter 2 Inhibitors on Bone Metabolism and Fracture Risk
Yangli Ye, Chenhe Zhao, Jing Liang, Yinqiu Yang, Mingxiang Yu, Xinhua Qu (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 8, 2019 Category: Drugs & Pharmacology Source Type: research

Some Prospective Alternatives for Treating Pain: The Endocannabinoid System and Its Putative Receptors GPR18 and GPR55
Raquel Guerrero-Alba, Paulino Barrag án-Iglesias, Abimael González-Hernández, Eduardo E. Valdez-Moráles, Vinicio Granados-Soto, Miguel Condés-Lara, Martín G. Rodríguez, Bruno A. Marichal-Cancino (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 8, 2019 Category: Drugs & Pharmacology Source Type: research

The Role of S1P and the Related Signaling Pathway in the Development of Tissue Fibrosis
Erjin Wang, Xingxuan He, Ming Zeng (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 8, 2019 Category: Drugs & Pharmacology Source Type: research

The Involvement of Sortilin/NTSR3 in Depression as the Progenitor of Spadin and Its Role in the Membrane Expression of TREK-1
Jean Mazella, Marc Borsotto, Catherine Heurteaux (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 8, 2019 Category: Drugs & Pharmacology Source Type: research

The Role of Nrf2 in Liver Disease: Novel Molecular Mechanisms and Therapeutic Approaches
Dongwei Xu, Min Xu, Seogsong Jeong, Yihan Qian, Hailong Wu, Qiang Xia, Xiaoni Kong (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 8, 2019 Category: Drugs & Pharmacology Source Type: research

Unveiling Active Constituents and Potential Targets Related to the Hematinic Effect of Steamed Panax notoginseng Using Network Pharmacology Coupled With Multivariate Data Analyses
Yin Xiong, Yupiao Hu, Lijuan Chen, Zejun Zhang, Yiming Zhang, Ming Niu, Xiuming Cui (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 8, 2019 Category: Drugs & Pharmacology Source Type: research