Exploring sleep characteristics in Chinese patients with narcolepsy: insights from the nocturnal sleep onset rapid eye movement period (nSOREMP)
Journal of Clinical Sleep Medicine, Ahead of Print. (Source: Journal of Clinical Sleep Medicine : JCSM)
Source: Journal of Clinical Sleep Medicine : JCSM - April 22, 2024 Category: Sleep Medicine Authors: Shufei Zeng
Fei Feng
Weimin Li
Yan Xu
Rui Zhao
Shengpeng Liang
Yihong Cheng
Ruichen Fang
Hailing Jia
Yang Wang
Dongsheng Lv
Bin Zhang
1Department of Psychiatry, Sleep Medicine Center, Nanfang Hospital, Southern Medical University
2Key Laboratory of Mental Source Type: research
Naringenin mitigates cadmium-induced cell death, oxidative stress, mitochondrial dysfunction, and inflammation in KGN cells by regulating the expression of sirtuin-1
. (Source: Drug and Chemical Toxicology)
Source: Drug and Chemical Toxicology - April 22, 2024 Category: Toxicology Authors: Ben YuanJunbiao MaoJunling WangShuhong LuoBingbing Luoa Department of Reproductive Medicine, Huangshi Central Hospital, Affiliated Hospital of Hubei Polytechnic University, Huangshi, Chinab Huangshi Key Laboratory of Assisted Reproduction and Reproductive Source Type: research
Principal component analysis of phenotypic and breeding value data for semen traits in Egyptian buffalo bulls
This study was conducted to assess the relationship between the breeding values as well as the phenotypic values for semen traits (VOL, MM, LS, AS and CONC) of the Egyptian buffalo bulls. A total of 7761 normal semen ejaculates were collected and characterized at ILMTC laboratory from 26 bulls from 2009 to 2019. For VOL, MM, LS, AS, and CONC, the actual means were 3.89 mL, 62.37%, 60.64%, 3.94%, and 0.67 × 109 sperm/mL, respectively. The prediction of breeding values for semen traits was estimated using a Bayesian procedure. The estimated standardized EBVs and phenotypic values were used in the principal component an...
Source: Tropical Animal Health and Production - April 22, 2024 Category: Veterinary Research Source Type: research
Renal artery coil embolization as an endovascular approach for establishing a rabbit model of chronic kidney disease
This study aimed to investigate the safety and feasibility of renal artery coil embolization for establishing chronic kidney disease (CKD) in rabbits. (Source: Journal of Vascular and Interventional Radiology : JVIR)
Source: Journal of Vascular and Interventional Radiology : JVIR - April 22, 2024 Category: Radiology Authors: Qijia Liu, Yun Pei, Qian Xie, Wenhan Bao, Xuan Li, Jingyuan Luan, Jintao Han Tags: Laboratory Investigation Source Type: research
Impact of the COVID-19 Pandemic on HIV Test Uptake Among People Who Inject Drugs in the Context of an HIV Outbreak
In conclusion, progress in increasing testing in response to the HIV outbreak has been eroded by COVID-19. Adoption of a linked data approach could be warranted in other settings to inform efforts to eliminate HIV transmission. (Source: AIDS and Behavior)
Source: AIDS and Behavior - April 22, 2024 Category: Infectious Diseases Source Type: research
External validation of a rapid algorithm using high-sensitivity troponin assay results for evaluating patients with suspected acute myocardial infarction
Conclusions
A 2-hour algorithm based on the HighSTEACS strategy using the Siemens Atellica IM hs-cTnI laboratory-based assay enables safe and efficient risk assessment of emergency patients with suspected AMI.
Trial registration number
ACTRN12621000053820. (Source: Emergency Medicine Journal)
Source: Emergency Medicine Journal - April 22, 2024 Category: Emergency Medicine Authors: Cullen, L., Greenslade, J. H., Stephensen, L., Ranasinghe, I., Gaikwad, N., Khorramshahi Bayat, M., Mahmoodi, E., Than, M., Apple, F., Parsonage, W., 2022 SAMIE study group Tags: Original research Source Type: research
High-sensitivity troponin testing at the point of care for the diagnosis of myocardial infarction: a prospective emergency department clinical evaluation
In the ED, laboratory high-sensitivity cardiac troponin (hs-cTn) tests facilitate ‘rule-out’ of myocardial infarction (MI).1 Contemporary point-of-care (POC) troponin tests have inferior analytical sensitivity,2 preventing rapid ‘rule-out’ strategies in near-patient settings. The new Siemens Atellica VTLi POC test meets hs-cTn criteria.3 Between June and September 2022, adult ED patients (≥16 years) with symptoms suspicious for MI and no ST-segment elevation on ECG were eligible for inclusion if staff trained on the POC instrument were available. Simultaneously, blood was taken for near-patient t...
Source: Emergency Medicine Journal - April 22, 2024 Category: Emergency Medicine Authors: Curran, J. M., Mergo, A., White, S., Croal, B. L., Cooper, J. G. Tags: Research letter Source Type: research
Determination of a whole-blood single-test low-risk threshold for a point-of-care high-sensitivity troponin assay
High-sensitivity troponin (hsTn) is used with ECG and clinical evaluation to stratify patients attending ED as low risk for acute myocardial infarctions (AMI). Diagnostic pathways incorporate a single test threshold for stratification with these assays. The Siemens Atellica VTLi Point-Of-Care-hsTnI assay (POC-hsTnI) has an 8 min turn-around which may expedite decision-making. Although a single-test low-risk (‘rule-out’) threshold for this assay has been reported,1 it was desirable to determine a threshold specifically for New Zealand ED settings and intended end-users. From 3 November 2022 to 28 May 2023, hsTnI...
Source: Emergency Medicine Journal - April 22, 2024 Category: Emergency Medicine Authors: Pickering, J. W., Hamill, L., Aldous, S., Joyce, L., Stothart, R. A., Williams, O., Florkowski, C. M., Than, M. Tags: Research letter Source Type: research
Evaluation of Ornidazole Tablets Bioequivalence in Chinese Healthy Participants Under Fasted and Fed Conditions Using Pharmacokinetic Parameters
ConclusionThe bioequivalence and tolerability of ornidazole tablet reference and test formulations were evaluated among healthy Chinese participants under both fasting and fed conditions. The results indicated that both formulations were bioequivalent and generally well tolerated; besides, the interaction between food and drug may affect drug pharmacokinetics.Trial RegistrationCTR20212873, registered on 15 November 2021; ChiCTR2300069098, registered on 7 March 2023. (Source: Drugs in R&D)
Source: Drugs in R&D - April 22, 2024 Category: Drugs & Pharmacology Source Type: research
Development of a non-infectious control for viral hemorrhagic fever PCR assays
by Matthew A. Knox, Collette Bromhead, David TS Hayman
Assay validation is an essential component of disease surveillance testing, but can be problematic in settings where access to positive control material is limited and a safety risk for handlers. Here we describe a single non-infectious synthetic control that can help develop and validate the PCR based detection of the viral causes of Crimean-Congo hemorrhagic fever, Ebola virus disease, Lassa fever, Marburg virus disease and Rift Valley fever. We designed non-infectious synthetic DNA oligonucleotide sequences incorporating primer binding sites suitable for five assay...
Source: PLoS Neglected Tropical Diseases - April 22, 2024 Category: Tropical Medicine Authors: Matthew A. Knox Source Type: research
Diagnosis, management, and outcomes of parechovirus infections in infants: an overview
Journal of Clinical Microbiology, Ahead of Print. (Source: Journal of Clinical Microbiology)
Source: Journal of Clinical Microbiology - April 22, 2024 Category: Microbiology Authors: Anjana SasidharanChristopher J. HarrisonRangaraj Selvarangan1Department of Pathology and Laboratory Medicine, Children ’s Mercy Hospital and Clinics, Kansas City, Missouri, USA2University of Missouri, College of Medicine, Kansas City, Missouri, USA Romn Source Type: research
Risk assessment of radon exposure inside residential dwellings in Safi city, Morocco
. (Source: International Journal of Environmental Analytical Chemistry)
Source: International Journal of Environmental Analytical Chemistry - April 22, 2024 Category: Chemistry Authors: Meryame JabbadeAbdellatif NachabMeryam El MoutmirFatima Ezzahra ElmoutmirAbdel-Mjid NourreddineMohammed BenjellounMohammed Fahada Laboratory of Nuclear, Atomic, Molecular, Mechanical and Energetic Physics, Department of Physics, Faculty of Sciences, Choua Source Type: research
Two cases of diquat poisoning in adolescent children
In this report, we compare two similar cases of juvenile diquat poisoning with dynamic changes in clinical manifestations, laboratory values, and imaging results. For the first time, the difference in whether to perform blood flow perfusion and the time difference of initiation of hemoperfusion had a clear clinical difference in the subsequent effects of diquat poisoning in children with diquat poisoning. Limited evidence is available regarding the efficacy of early hemoperfusion for diquat poisoning; however, the differences in clinical outcomes articulated here highlight the benefits of early and timely hemoperfusion the...
Source: Italian Journal of Pediatrics - April 22, 2024 Category: Pediatrics Source Type: research
HELLP Syndrome at 20 Gestational Weeks Managed Using the Mississippi Protocol: A Case Report
This report indicates that early and intensive treatment of patients with HELLP syndrome occurring before 22 GWs according to the Mississippi protocol may enable clinicians to complete pregnancy termination without maternal complications and provide useful information to clinical practitioners in perinatal medicine.PMID:38644297 | DOI:10.24546/0100488386 (Source: Kobe J Med Sci)
Source: Kobe J Med Sci - April 21, 2024 Category: General Medicine Authors: Naohisa Masuko Kenji Tanimura Masayuki Tanaka Akiko Uchida Ryosuke Takahashi Hitomi Imafuku Masashi Deguchi Yoshito Terai Source Type: research
< em > Fretibacterium < /em > Species to < em > Fusobacterium periodonticum < /em > Ratio as a Potential Biomarker of Periodontitis Based on Salivary Microbiome Profiling
Ann Lab Med. 2024 Apr 22. doi: 10.3343/alm.2024.0043. Online ahead of print.NO ABSTRACTPMID:38644360 | DOI:10.3343/alm.2024.0043 (Source: Annals of Laboratory Medicine)
Source: Annals of Laboratory Medicine - April 21, 2024 Category: Laboratory Medicine Authors: Eun Ji Oh Hyun Hee Jang Sangwon Park Hyun-Pil Lim Kwi-Dug Yun Woohyung Jang Ok-Su Kim Chan Park Eun Jeong Won Source Type: research
