Correction to: Novel mutation in carnitine palmitoyltransferase 1A detected through newborn screening for a presymptomatic case in China: a case report
(Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - September 21, 2021 Category: Pediatrics Authors: Yi Gan, Fei Yu and Haining Fang Tags: Correction Source Type: research

Are we sure that the neurological impact of COVID 19 in childhood has not been underestimated?
ConclusionsBased on data showing the neurologic impact of COVID-19 in pediatric age, we suggest monitoring neurological development a few months after healing in pediatric patients who have presented MIS-C, seizures or other neurological manifestations and in children of pregnant women with COVID-19 in order to detect overt and subtle deficits. (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - September 18, 2021 Category: Pediatrics Source Type: research

Are we sure that the neurological impact of COVID 19 in childhood has not been underestimated?
Presently, it is known that, even if less frequently than in adults, children can develop a severe new coronavirus disease 2019 (COVID-19). Children with the SARS-CoV-2 infection can have neurological signs an... (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - September 18, 2021 Category: Pediatrics Authors: Nicola Principi and Susanna Esposito Tags: Debate Source Type: research

15q26 deletion in a patient with congenital heart defect, growth restriction and intellectual disability: case report and literature review
15q26 deletion is a relatively rare chromosomal disorder, and it is described only in few cases. Patients with this aberration show many signs and symptoms, particularly pre- and postnatal growth restriction, ... (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - September 16, 2021 Category: Pediatrics Authors: Yahya Benbouchta, Nicole De Leeuw, Saadia Amasdl, Aziza Sbiti, Dominique Smeets, Khalid Sadki and Abdelaziz Sefiani Tags: Case report Source Type: research

Balloon dilation and rapid maxillary expansion: a novel combination treatment for congenital nasal pyriform aperture stenosis in an infant
Congenital nasal pyriform aperture stenosis (CNPAS) is a rare condition that may occur alone or as part of a multi-formative syndrome. Management remains difficult. There is no specific treatment protocol. Tra... (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - September 16, 2021 Category: Pediatrics Authors: Emanuela Sitzia, Sara Santarsiero, Filippo Maria Tucci, Giovanni De Vincentiis, Angela Galeotti and Paola Festa Tags: Case report Source Type: research

In-hospital and web-based intervention to counteract vaccine hesitancy in very preterm infants ’ families: a NICU experience
Vaccine hesitancy is a global problem, carrying significant health risks for extremely vulnerable population as that of preterm infants. Social media are emerging as significant tools for public health promoti... (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - September 16, 2021 Category: Pediatrics Authors: Antonio Di Mauro, Federica Di Mauro, Chiara Greco, Orazio Valerio Giannico, Francesca Maria Grosso, Maria Elisabetta Baldassarre, Manuela Capozza, Federico Schettini, Pasquale Stefanizzi and Nicola Laforgia Tags: Research Source Type: research

In-hospital and web-based intervention to counteract vaccine hesitancy in very preterm infants ’ families: a NICU experience
AbstractBackgroundVaccine hesitancy is a global problem, carrying significant health risks for extremely vulnerable population as that of preterm infants. Social media are emerging as significant tools for public health promotion. Our aim was to evaluate both the coverage and the timeliness of routine immunizations in a cohort of preterm infants (  0.05), while timeliness of administration was significantly delayed compared to the recommended schedule (p   0.05). DTaP-IPV-HBV-Hib 2nd and 3rd doses, MMR and Varicella vaccines coverage data were higher compared to historical cohort (p 
Source: Italian Journal of Pediatrics - September 16, 2021 Category: Pediatrics Source Type: research

Balloon dilation and rapid maxillary expansion: a novel combination treatment for congenital nasal pyriform aperture stenosis in an infant
ConclusionsA combination of minimally invasive balloon surgery and placement of a palatal device may successfully treat CNPAS; it may also treat other types of nasal bone stenosis. Future studies may allow the development of practice consensus treatment strategies. (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - September 16, 2021 Category: Pediatrics Source Type: research

15q26 deletion in a patient with congenital heart defect, growth restriction and intellectual disability: case report and literature review
ConclusionWe report on an additional case of 15q26  monosomy, characterized by array-CGH. Molecular cytogenetic analysis allowed us to identify the exact size of the deletion, and four candidate genes for genotype-phenotype correlation. 15q26 monosomy should be considered when growth retardation is associated with hearing anomalies and congenita l heart defect, especially atrioventricular septal defects (AVSDs) and/or aortic arch anomaly (AAA). (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - September 16, 2021 Category: Pediatrics Source Type: research

Incidence and predictors of mortality among neonates referred to comprehensive and specialized hospitals in Amhara regional state, North Ethiopia: a prospective follow-up study
Neonatal mortality is a major global public health problem. Ethiopia is among seven countries that comprise 50 % of global neonatal mortality. Evidence on neonatal mortality in referred neonates is essential f... (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - September 15, 2021 Category: Pediatrics Authors: Alex Yeshaneh, Bizuayehu Tadele, Bogale Dessalew, Mulunesh Alemayehu, Awraris Wolde, Addisu Adane, Solomon Shitu, Haimanot Abebe and Daniel Adane Tags: Research Source Type: research

High levels of unbound bilirubin are associated with acute bilirubin encephalopathy in post-exchange transfusion neonates
Although it is known that unbound bilirubin can enter the brain, there is little evidence of its association with the development of acute bilirubin encephalopathy. Here, we investigated this potential relatio... (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - September 15, 2021 Category: Pediatrics Authors: Yiyi Ding, Shuo Wang, Rui Guo, Aizhen Zhang and Yufang Zhu Tags: Research Source Type: research

Incidence and predictors of mortality among neonates referred to comprehensive and specialized hospitals in Amhara regional state, North Ethiopia: a prospective follow-up study
AbstractBackgroundNeonatal mortality is a major global public health problem. Ethiopia is among seven countries that comprise 50 % of global neonatal mortality. Evidence on neonatal mortality in referred neonates is essential for intervention however, there is no enough information in the study area. Neonates who required referral frequently became unstable and were at a high risk of death. Therefore, this study aimed to assess the incidence and predictors of mortality among referred neonates.MethodA prospective follow-up study was conducted among 436 referred neonates at comprehensive specialized hospitals in the Amhara r...
Source: Italian Journal of Pediatrics - September 15, 2021 Category: Pediatrics Source Type: research

High levels of unbound bilirubin are associated with acute bilirubin encephalopathy in post-exchange transfusion neonates
AbstractBackgroundAlthough it is known that unbound bilirubin can enter the brain, there is little evidence of its association with the development of acute bilirubin encephalopathy. Here, we investigated this potential relationship in neonates who had undergone exchange transfusion.MethodsData from 46 newborns who underwent exchange transfusion between 2016 and 1-1 to 2018-12-31 at the First People ’s Hospital of Changde City in China were analyzed. The unbound bilirubin level was taken as the independent variable and the development of the acute bilirubin encephalopathy as the dependent variable. The covariates wer...
Source: Italian Journal of Pediatrics - September 15, 2021 Category: Pediatrics Source Type: research

Correction to: Incidental finding of APC deletion in a child: double trouble or double chance? – a case report
(Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - September 14, 2021 Category: Pediatrics Source Type: research

Analysis of risk and prognostic factors in a population of pediatric patients hospitalized for acute malnutrition at the Chiulo hospital, Angola
Malnutrition is a multifactorial pathology in which genetic, epigenetic, cultural, environmental, socio-economic factors interact with each other. The impact that this disease has on the health of children wor... (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - September 10, 2021 Category: Pediatrics Authors: Federica Maria Tripoli, Salvatore Accomando, Simona La Placa, Andrea Pietravalle, Giovanni Putoto, Giovanni Corsello and Mario Giuffr è Tags: Research Source Type: research

Analysis of risk and prognostic factors in a population of pediatric patients hospitalized for acute malnutrition at the Chiulo hospital, Angola
AbstractBackgroundMalnutrition is a multifactorial pathology in which genetic, epigenetic, cultural, environmental, socio-economic factors interact with each other. The impact that this disease has on the health of children worldwide is dramatic. Severe acute malnutrition in particular is a disease affecting nearly 20 million preschool children worldwide, most of them in Africa and South East Asia.ObjectivesThis work aims to investigate potential prognostic factors in the clinical evolution of acute malnutrition and potential risk factors for the development of the disease.MethodsOur study was carried out at the “Hos...
Source: Italian Journal of Pediatrics - September 10, 2021 Category: Pediatrics Source Type: research

Pediatric health care professionals ’ vaccine knowledge, awareness and attitude: a survey within the Italian Society of Pediatric Allergy and Immunology
Physicians play a key role in driving vaccine acceptance and their recommendations are crucial to address vaccine hesitancy. The aim of the study was to assess knowledge, awareness and attitude of Italian Pedi... (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - September 9, 2021 Category: Pediatrics Authors: Elisabetta Del Duca, Loredana Chini, Simona Graziani, Mayla Sgrulletti and Viviana Moschese Tags: Research Source Type: research

Pediatric health care professionals ’ vaccine knowledge, awareness and attitude: a survey within the Italian Society of Pediatric Allergy and Immunology
AbstractBackgroundPhysicians play a key role in driving vaccine acceptance and their recommendations are crucial to address vaccine hesitancy. The aim of the study was to assess knowledge, awareness and attitude of Italian Pediatric Health Care Professionals (pHCPs) on vaccinations.MethodsAn anonymous on-line questionnaire was developed within the Vaccine Committee of Italian Society of Pediatric Allergy and Immunology (SIAIP) and spontaneously completed by 231 Pediatricians and Pediatric Nurses (PN).ResultsAn accurate vaccine education was reported by 70% of pediatricians and 13% of PN but 11% of pediatricians versus 26% ...
Source: Italian Journal of Pediatrics - September 9, 2021 Category: Pediatrics Source Type: research

Surgical site infection after delayed sternal closure in neonates with congenital heart disease: retrospective case-control study
To determine the prevalence of surgical site infections (SSIs) in neonatal congenital heart disease patients undergoing delayed sternal closure (DSC) and evaluate risk factors for SSI. (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - September 8, 2021 Category: Pediatrics Authors: Yuzhong Yang, Jie Wang, Lina Cai, Wei Peng and Xuming Mo Tags: Research Source Type: research

Surgical site infection after delayed sternal closure in neonates with congenital heart disease: retrospective case-control study
ConclusionsWith the prolongation of aortic clamping duration, the probability of occurrence of SSI increased in neonatal CHD with DSC. The age at operation and body weight are closely related to the occurrence of SSI in neonatal CHD patients with DSC. (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - September 8, 2021 Category: Pediatrics Source Type: research

Delayed pubarche
In healthy adolescents, delayed pubarche is generally a benign condition that is caused by a physiological discrepancy between gonadarche and adrenarche. In presence of other clinical signs and symptoms, delay... (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - September 6, 2021 Category: Pediatrics Authors: Francesco Baldo, Egidio Barbi and Gianluca Tornese Tags: Review Source Type: research

Peripheral nervous system manifestations of Shiga toxin-producing E. coli-induced haemolytic uremic syndrome in children
The Neurological involvement is the most common extra-renal complication of Shiga toxin-producing E. coli-hemolytic uremic syndrome (HUS) or typical HUS. On brain magnetic resonance examination, main neurological... (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - September 6, 2021 Category: Pediatrics Authors: Luisa Santangelo, Giuseppe Stefano Netti, Diletta Domenica Torres, Giovanni Piscopo, Vincenza Carbone, Luciana Losito, Leonardo Milella, Maria Luigia Lasorella, Pasquale Conti, Delio Gagliardi, Maria Chironna, Federica Spadaccino, Elena Bresin, Antonio Tr Tags: Case report Source Type: research

Delayed pubarche
AbstractIn healthy adolescents, delayed pubarche is generally a benign condition that is caused by a physiological discrepancy between gonadarche and adrenarche. In presence of other clinical signs and symptoms, delayed pubarche can be caused by single or multiple hormones deficiency (such as adrenal insufficiency, panhypopituitarism and hypothyroidism) and/or genetic conditions (Turner syndrome, androgen insensitivity syndrome). Exposition to endocrine disruptors has also been described as a possible cause of delay of pubic hair development. Basic blood tests, karyotype and first level imaging studies are helpful in the d...
Source: Italian Journal of Pediatrics - September 6, 2021 Category: Pediatrics Source Type: research

Peripheral nervous system manifestations of Shiga toxin-producing E. coli-induced haemolytic uremic syndrome in children
ConclusionsPNS manifestations during typical HUS are a rare event and potentially leading to severe disability. A timely clinical assessment is mandatory to set up a prompt therapeutic and rehabilitation program and to obtain a complete clinical and functional recovery. (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - September 6, 2021 Category: Pediatrics Source Type: research

Italian consensus on the therapeutic management of uncomplicated acute hematogenous osteomyelitis in children
Acute hematogenous osteomyelitis (AHOM) is an insidious infection of the bone that more frequently affects young males. The etiology, mainly bacterial, is often related to the patient ’s age, but it is frequent... (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - August 28, 2021 Category: Pediatrics Authors: Andrzej Krzysztofiak, Elena Chiappini, Elisabetta Venturini, Livia Gargiullo, Marco Roversi, Carlotta Montagnani, Elena Bozzola, Sara Chiurchiu, Davide Vecchio, Elio Castagnola, Paolo Tom à, Gian Maria Rossolini, Renato Maria Toniolo, Susanna Esposito, M Tags: Review Source Type: research

Italian consensus on the therapeutic management of uncomplicated acute hematogenous osteomyelitis in children
ConclusionsThe therapeutic management of osteomyelitis is still object of controversy. This study reports the first Italian consensus on the management of uncomplicated AHOM in children of pediatric osteomyelitis, based on expert opinions and a vast literature review. (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - August 28, 2021 Category: Pediatrics Source Type: research

IL-23/Th17 pathway and IL-17A gene polymorphism in Egyptian children with immune thrombocbytopenic purpura
Immune thrombocytopenic purpura (ITP) is an acquired complex autoimmune thrombocytopenia. Uncontrolled cellular immune response is one of the key triggers for the loss of immune tolerance in ITP patients. The ... (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - August 26, 2021 Category: Pediatrics Authors: Ahlam M. Ismail, Aliaa M. Higazi, Hanan M. Nomeir and Naglaa M. Farag Tags: Research Source Type: research

IL-23/Th17 pathway and IL-17A gene polymorphism in Egyptian children with immune thrombocbytopenic purpura
AbstractBackgroundImmune thrombocytopenic purpura (ITP) is an acquired complex autoimmune thrombocytopenia. Uncontrolled cellular immune response is one of the key triggers for the loss of immune tolerance in ITP patients. The purpose of this study was to investigate the association of IL-23/Th17, IL-17A andIL-17A rs2275913 gene polymorphism with ITP in Egyptian children.Methods60 patients with ITP and 50 healthy control children from Minia city- Egypt  were involved. Serum levels of IL-23 and IL-17A were determined by enzyme-linked immunosorbent assay. The frequency of Th17 cells was measured using flow cytometer. Ge...
Source: Italian Journal of Pediatrics - August 26, 2021 Category: Pediatrics Source Type: research

Dietary treatment of congenital chylothorax with skimmed breast milk
Congenital chylothorax (CC) is a rare but potentially life-threatening condition in newborns. It is defined as an accumulation of chyle in the pleural cavity. The few publications regarding medical management ... (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - August 26, 2021 Category: Pediatrics Authors: Michaela H öck, Alexander Höller, Marlene Hammerl, Karina Wechselberger, Jakob Krösslhuber, Ursula Kiechl-Kohlendorfer, Sabine Scholl-Bürgi and Daniela Karall Tags: Research Source Type: research

Post-traumatic stress disorder (PTSD) in parents of children with type 1 diabetes during Covid-19 pandemic
The Post-traumatic Stress Disorder (PTSD) is a group of persistent psychological and physiological symptoms due to a traumatic, severe, event. Only few studies focused on the effects of Covid-19 on psychosocia... (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - August 26, 2021 Category: Pediatrics Authors: C. Carducci, N. Rapini, A. Deodati, V. Pampanini, S. Cianfarani and R. Schiaffini Tags: Research Source Type: research

Clinical features of pediatric post-acute COVID-19: a descriptive retrospective follow-up study
To date, information on COVID-19 long-term post-recovery sequelae in children and adolescents remains scarce. A retrospective descriptive cohort study was performed by collecting data on 92 patients (age  ≤ 18 ... (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - August 26, 2021 Category: Pediatrics Authors: Liene Smane, Ieva Roge, Zanda Pucuka and Jana Pavare Tags: Letter to the Editor Source Type: research

Dietary treatment of congenital chylothorax with skimmed breast milk
ConclusionThe first-line therapy of chylothorax is a combination of respiratory stabilization and dietary modification. The use of skimmed breast milk is advisable in CC and feasible by means of a simple milk defatting procedure. It offers benefits to mothers who wish to resume breast feeding after resolution of chylothorax and has proven positive effects, above all in preterm infants as optimal nutrition with protective components superior to formula feeding. However, the nutritional analysis of the skimmed milk and the correlation to a re-accumulation of pleural fluid remains a question to be answered. (Source: Italian J...
Source: Italian Journal of Pediatrics - August 26, 2021 Category: Pediatrics Source Type: research

Clinical features of pediatric post-acute COVID-19: a descriptive retrospective follow-up study
AbstractTo date, information on COVID-19 long-term post-recovery sequelae in children and adolescents remains scarce. A retrospective descriptive cohort study was performed by collecting data on 92 patients (age  ≤ 18 years). All were evaluated during a face-to-face visit following a specially designed post-COVID-19 symptom assessment protocol at the following stage: 1–3 months after COVID-19 onset. Among the 92 children, 45 (49%) were completely free of any COVID-19-related symptoms, while 47 ( 51%) reported persistence of at least one symptom, in particular tiredness, loss of taste an...
Source: Italian Journal of Pediatrics - August 26, 2021 Category: Pediatrics Source Type: research

Post-traumatic stress disorder (PTSD) in parents of children with type 1 diabetes during Covid-19 pandemic
ConclusionsThe present study confirms a high prevalence symptoms related to PTSD in mothers and fathers of children with Type 1 Diabetes. We believe that psychosocial outcomes of the COVID-19 pandemic should be taken into account in the planning of the next future assistance for children with T1D. (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - August 26, 2021 Category: Pediatrics Source Type: research

Water, sanitation, and hygiene as a priority intervention for stunting in under-five children in northwest Ethiopia: a community-based cross-sectional study
AbstractBackgroundStunting was a significant public health problem for under-five in developing countries including Ethiopia. Globally, it was estimated 21.9% or 149 million (81.7 million in Asia and 58.8 million in Africa) under-five children stunted in 2018. In East Africa, 24 million are stunted which is the highest-burden from African regions. Hence, this study aimed to assess the prevalence of stunting and its association with Water Sanitation and Hygiene (WASH) in northwestern Ethiopia.MethodA community-based cross-sectional study design was conducted among 630 participants from December to mid-January 2019. From fiv...
Source: Italian Journal of Pediatrics - August 24, 2021 Category: Pediatrics Source Type: research

Water, sanitation, and hygiene as a priority intervention for stunting in under-five children in northwest Ethiopia: a community-based cross-sectional study
Stunting was a significant public health problem for under-five in developing countries including Ethiopia. Globally, it was estimated 21.9% or 149 million (81.7 million in Asia and 58.8 million in Africa) und... (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - August 24, 2021 Category: Pediatrics Authors: Ayechew Ademas, Metadel Adane, Awoke Keleb, Gete Berihun and Getu Tesfaw Tags: Research Source Type: research

The exacerbated prevalence of acute malnutrition and growth retardation in Roma children living in camps
ConclusionsMalnutrition in immigrant children is still of high concern in Italy. Its prevalence in Roma children living in extra-urban camps exceeds that of immigrant children living in urban areas and the rates of underweight, stunting and wasting of Roma children living in the Balkans. This exacerbating condition highlights the need of better assisting this fragile population that is at most risk of poverty, food insecurity and social exclusion in Italy, particularly during this pandemic crisis. (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - August 21, 2021 Category: Pediatrics Source Type: research

The exacerbated prevalence of acute malnutrition and growth retardation in Roma children living in camps
Child malnutrition is still a concern in marginalized groups of populations, such as immigrants living in very low socio-economic conditions. Roma children are within the most hard-to-reach populations, suscep... (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - August 21, 2021 Category: Pediatrics Authors: Rosaria Giampaolo, Rosaria Marotta, Francesco Saverio Biagiarelli, Antonella Zampa, Stefania Moramarco and Ersilia Buonomo Tags: Research Source Type: research

Magnitude of anemia and associated factors among children aged 6 –59 months at Debre Markos referral hospital, Northwest Ethiopia: a hospital-based cross-sectional study
AbstractBackgroundAnemia, the most common micro-nutrient deficiency disorder, is the world ’s second leading cause of morbidity and morbidity, affecting 24.8% of the population, of which 47.4% are under-five children. The prevalence of anemia ranges from 44 to 56% in Ethiopia. Although its magnitude has shown decreases across regions; it continues to be a significant public health probl em, particularly in developing countries including Ethiopia. Despite this evidence, the magnitude and associated factors of anemia was not systematically explored and there is a limited information or limited evidences in the study ar...
Source: Italian Journal of Pediatrics - August 13, 2021 Category: Pediatrics Source Type: research

Magnitude of anemia and associated factors among children aged 6 –59 months at Debre Markos referral hospital, Northwest Ethiopia: a hospital-based cross-sectional study
Anemia, the most common micro-nutrient deficiency disorder, is the world ’s second leading cause of morbidity and morbidity, affecting 24.8% of the population, of which 47.4% are under-five children. The preval... (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - August 13, 2021 Category: Pediatrics Authors: Yoseph Merkeb Alamneh, Tadesse Yirga Akalu, Abtie Abebaw Shiferaw and Aytenew Atnaf Tags: Research Source Type: research

Social media use to improve communication on children and adolescent ’s health: the role of the Italian Paediatric Society influencers
Fake news on children ’s and adolescent health are spreading. Internet availability and decreasing costs of media devices are contributing to an easy access to technology by families. Public health organization... (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - August 11, 2021 Category: Pediatrics Authors: Elena Bozzola, Anna Maria Staiano, Giulia Spina, Nicola Zamperini, Francesco Marino, Marco Roversi and Giovanni Corsello Tags: Research Source Type: research

Social media use to improve communication on children and adolescent ’s health: the role of the Italian Paediatric Society influencers
ConclusionOur study shows the potential role of influencers: spreading health messages via PI seems to be a successful strategy to promote correct communication about children ’s and adolescents’ health. (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - August 11, 2021 Category: Pediatrics Source Type: research

Linguistic adaptation and psychometric evaluation of Italian version of children ’s sleep habits questionnaire
ConclusionCSHQ-IT is a valuable tool for evaluating sleep behavior in children 4 –10 years-old in Italy. Future research should be implemented to provide definitive validity of CSHQ-IT in children with sleep-disordered breathing. (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - August 9, 2021 Category: Pediatrics Source Type: research

Linguistic adaptation and psychometric evaluation of Italian version of children ’s sleep habits questionnaire
The Children ’s Sleep Habits Questionnaire (CSHQ) is a parent-report questionnaire used to examine sleep behavior in children. Linguistic adaptation of CSHQ into several languages and/or psychometric analysis o... (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - August 9, 2021 Category: Pediatrics Authors: Melissa Borrelli, Iris Scala, Paola Festa, Dario Bruzzese, Ambrosina Michelotti, Elena Cantone, Adele Corcione, Martina Fragnito, Vincenzo Miranda and Francesca Santamaria Tags: Letter to the Editor Source Type: research

Hypertonic saline in people with cystic fibrosis: review of comparative studies and clinical practice
AbstractCystic fibrosis (CF) is a multisystem disorder, caused by mutations in the CF transmembrane conductance regulator (CFTR) gene. These cause a reduced secretion of chloride, a marked absorption of sodium and, therefore, of water, through the epithelium, resulting in the formation of thickened secretions in organs such as lung or pancreas. These viscous secretions lead to airway obstruction, chronic infection and inflammation resulting in progressive lung damage, bronchiectasis and eventual respiratory failure. Although the average life expectancy has increased over the last 30  years, lung disease is the most ...
Source: Italian Journal of Pediatrics - August 6, 2021 Category: Pediatrics Source Type: research

Optimizing gentamicin dosing in different pediatric age groups using population pharmacokinetics and Monte Carlo simulation
This study aimed to derive a population pharmacokinetic model of gentamicin and apply it to design optimal dosing regimens in pediatrics.MethodsPopulation pharmacokinetics of gentamicin in pediatrics was described from a retrospective chart review of plasma gentamicin concentration data (peak/ trough levels) of pediatric patients (1  month − 12 years), admitted to non-critically ill pediatrics. Monte Carlo simulations were performed on the resulting pharmacokinetic model to assess the probability of achieving a Cmax/MIC target of 10  mg/L over a range of gentamicin MICs of 0.5–2&thin...
Source: Italian Journal of Pediatrics - August 6, 2021 Category: Pediatrics Source Type: research

Antibiotic-resistant profile and the factors affecting the intravenous antibiotic treatment course of generalized Staphylococcal Scalded Skin Syndrome: a retrospective study
AbstractBackgroundStaphylococcal Scalded Skin Syndrome (SSSS) is caused by a special type ofStaphylococcus aureus (S.aureus) which can produce exfoliative toxins. The generalized SSSS is recommended to be admitted and treated with intravenous antibiotics. However, there were limited reports on whether personal and clinical factors can have impacts on the duration of intravenous antibiotic application for pediatric patients with generalized SSSS.We performed a study to assess the factors affecting intravenous antibiotic treatment course of SSSS patients. Additionally, the positive culture rates ofS.aureus in different sampl...
Source: Italian Journal of Pediatrics - August 6, 2021 Category: Pediatrics Source Type: research

Optimizing gentamicin dosing in different pediatric age groups using population pharmacokinetics and Monte Carlo simulation
This study aimed to derive a population pharmacokine... (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - August 6, 2021 Category: Pediatrics Authors: Ragia H. Ghoneim, Abrar K. Thabit, Manar O. Lashkar and Ahmed S. Ali Tags: Research Source Type: research