Development and Validation of a Sociodemographic and Behavioral Characteristics-Based Risk-Score Algorithm for Targeting HIV Testing Among Adults in Kenya
AbstractTo inform targeted HIV testing, we developed and externally validated a risk-score algorithm that incorporated behavioral characteristics. Outpatient data from five health facilities in western Kenya, comprising 19,458 adults  ≥ 15 years tested for HIV from September 2017 to May 2018, were included in univariable and multivariable analyses used for algorithm development. Data for 11,330 adults attending one high-volume facility were used for validation. Using the final algorithm, patients were grouped into four ri sk-score categories: ≤ 9, 10–15, 16–29 and &...
Source: AIDS and Behavior - July 10, 2020 Category: Infectious Diseases Source Type: research

CDC ’s Community-Based Organization Behavioral Outcomes Project: Perspectives for Researchers, Implementers and Funders
AbstractBehavioral interventions have been a crucial tool for the prevention of HIV transmission since early in the epidemic. The Centers for Disease Control and Prevention (CDC) has provided funding for evidence-based behavioral interventions (EBIs) at health departments and community-based organizations (CBOs) since 2004. From 2006 to 2015, CDC funded 25 CBOs to evaluate one or more of seven EBIs designed to prevent HIV through the Community-based Organization Behavioral Outcomes Project (CBOP) as implemented outside of a research setting. For each EBI, CBOP showed that most HIV risk behaviors improved after the interven...
Source: AIDS and Behavior - July 9, 2020 Category: Infectious Diseases Source Type: research

Combination HIV Prevention Strategies Among Montreal Gay, Bisexual, and Other Men Who Have Sex with Men in the PrEP Era: A Latent Class Analysis
Abstract Pre-exposure prophylaxis (PrEP) became publicly available in Quebec for gay, bisexual and other men who have sex with men (GBM) in 2013. We used baseline data from Engage, a cohort of GBM recruited by respondent-driven sampling, to examine patterns of combination HIV prevention use among Montreal GBM since PrEP became available. Latent class analysis, stratified by HIV status, was used to categorize GBM by self-reported use of biomedical and behavioural prevention strategies. Correlates of resulting classes were identified using multinomial logistic regression. Among HIV-negative/unknown GBM (n  = 96...
Source: AIDS and Behavior - July 9, 2020 Category: Infectious Diseases Source Type: research

Factors Associated with Preferred Pre-Exposure Prophylaxis Dosing Regimen Among Men Who Have Sex with Men in Real-World Settings: A Mixed-Effect Model Analysis
AbstractWhen provided with both choices of pre-exposure prophylaxis (PrEP) in MSM, men may choose to use either method based on their sexual practice. The study objective was to describe the switches between dosing regimens and identify factors that predict choice of a dosing regimen among MSM. We performed a multi-center, observational, prospective PrEP cohort study conducted at three study sites in Taiwan between January 2018 and March 2019. A total of 215 participants made 469 visits. In half of the visits (49.7%), participants reported using on-demand PrEP. There were 36 regimen switches: 20 from daily to on-demand and...
Source: AIDS and Behavior - July 8, 2020 Category: Infectious Diseases Source Type: research

Family Contextual Factors are Differentially Associated with Depressive Symptoms among Boys and Girls with Perinatally Acquired HIV
AbstractYouth with perinatally acquired HIV (PHIV) are at risk for depressive symptoms, which are associated with a range of adverse outcomes. Although family contextual factors associated with depressive symptoms differ among boys and girls without PHIV, it is unclear whether this is also the case among youth with PHIV. Participants included 314 youth with PHIV (M = 12.88,SD = 3.08 years old; 51% male; 85% Black/Latinx) and their caregivers. Higher levels of caregivers’ own depressive symptoms, caregiver-child detachment, and family conflict were associated with higher levels of care...
Source: AIDS and Behavior - July 8, 2020 Category: Infectious Diseases Source Type: research

Starting or Switching to an Integrase Inhibitor-Based Regimen Affects PTSD Symptoms in Women with HIV
AbstractAs the use of Integrase inhibitor (INSTI)-class antiretroviral medications becomes more common to maintain long-term viral suppression, early reports suggest the potential for CNS side-effects when starting or switching to an INSTI-based regimen. In a population already at higher risk for developing mood and anxiety disorders, these drugs may have significant effects on PTSD scale symptom scores, particularly in women with HIV (WWH). A total of 551 participants were included after completing  ≥ 1 WIHS study visits before and after starting/switching to an INSTI-based ART regimen. Of these, 14% were...
Source: AIDS and Behavior - July 7, 2020 Category: Infectious Diseases Source Type: research

Disclosure, Social Support, and Mental Health are Modifiable Factors Affecting Engagement in Care of Perinatally-HIV Infected Adolescents: A Qualitative Dyadic Analysis
AbstractAdolescents living with perinatally acquired HIV in South Africa face significant barriers to successful transition from pediatric to adult care. We performed in-depth qualitative interviews with 41 adolescents living with HIV and 18 of their caregivers to investigate modifiable factors to improve engagement in care prior to transition to adult care. Based on dyadic, inductive content analysis, findings suggest that HIV status disclosure, social support, and mental health are targets for improvement in engagement in care. Early disclosure and a sense of belonging facilitated engagement in care, while barriers inclu...
Source: AIDS and Behavior - July 7, 2020 Category: Infectious Diseases Source Type: research

HIV Stigma and Its Associations with Longitudinal Health Outcomes Among Persons Living with HIV with a History of Unhealthy Alcohol Use
This study examined the demographic and clinical correlates of HIV stigma and evaluated how HIV stigma was associated with physical and mental health outcomes one year later in a primary-care based cohort of persons living with HIV (PLHIV; N  = 584). HIV stigma was measured using a modified Berger HIV stigma scale, which includes four subscales: (1) personalized stigma; (2) disclosure concerns; (3) negative self-image; and (4) concerns around public attitudes towards PLHIV. Physical and mental health were assessed using the 12-item short form survey (SF-12). Compared to whites, African Americans were more lik...
Source: AIDS and Behavior - July 6, 2020 Category: Infectious Diseases Source Type: research

Alcohol Use and Antiretroviral Adherence Among Patients Living with HIV: Is Change in Alcohol Use Associated with Change in Adherence?
AbstractAlcohol use increases non-adherence to antiretroviral therapy (ART) among persons living with HIV (PLWH). Dynamic longitudinal associations are understudied. Veterans Aging Cohort Study (VACS) data 2/1/2008 –7/31/16 were used to fit linear regression models estimating changes in adherence (% days with ART medication fill) associated with changes in alcohol use based on annual clinically-ascertained AUDIT-C screening scores (range − 12 to + 12, 0 = no change) adjusting for demographics and i nitial adherence. Among 21,275 PLWH (67,330 observations), most reported no (48%) or l...
Source: AIDS and Behavior - July 2, 2020 Category: Infectious Diseases Source Type: research

Clinical Care, Research, and Telehealth Services in the Era of Social Distancing to Mitigate COVID-19
(Source: AIDS and Behavior)
Source: AIDS and Behavior - June 25, 2020 Category: Infectious Diseases Source Type: research

COVID-19, Telemedicine, and Patient Empowerment in HIV Care and Research
(Source: AIDS and Behavior)
Source: AIDS and Behavior - June 25, 2020 Category: Infectious Diseases Source Type: research

COVID-19 and Hidden Housing Vulnerabilities: Implications for Health Equity, New Haven, Connecticut
(Source: AIDS and Behavior)
Source: AIDS and Behavior - June 25, 2020 Category: Infectious Diseases Source Type: research

Understanding the Impact of COVID-19 on Latino Sexual Minority Men in a US HIV Hot Spot
(Source: AIDS and Behavior)
Source: AIDS and Behavior - June 25, 2020 Category: Infectious Diseases Source Type: research

Research with Marginalized Communities: Challenges to Continuity During the COVID-19 Pandemic
(Source: AIDS and Behavior)
Source: AIDS and Behavior - June 25, 2020 Category: Infectious Diseases Source Type: research

Examining Correlates of Pre-ART and Early ART Adherence to Identify Key Factors Influencing Adherence Readiness
We examined correlates of multiple adherence readiness measures, as well as electronically measured early ART adherence, to identify variables most important for readiness to adhere well at the start of treatment. Education level, recency of HIV diagnosis and knowledge and commitment to adherence were found to be associated with both ART readiness and early ART adherence. These findings suggest that resources to support adherence readiness should target more experienced HIV patients, and strive to bolster knowledge and attitudes that reinforce commitment to adherence. (Source: AIDS and Behavior)
Source: AIDS and Behavior - June 22, 2020 Category: Infectious Diseases Source Type: research

“She Just Told Me Not To Cry”: A Qualitative Study of Experiences of HIV Testing and Counseling (HTC) Among Pregnant Women Living with HIV in Tanzania
AbstractHIV testing and counseling (HTC) in antenatal care is extremely effective at identifying women living with HIV and linking them to HIV care. However, retention is suboptimal in this population. We completed qualitative interviews with 24 pregnant women living with HIV in Tanzania to explore perceptions of HTC. Participants described intense shock and distress upon testing positive, including concerns about HIV stigma and disclosure; however, these concerns were rarely discussed in HTC. Nurses were generally kind, but relied on educational content and brief reassurances, leaving some participants feeling unsupported...
Source: AIDS and Behavior - June 22, 2020 Category: Infectious Diseases Source Type: research

Enacted HIV-Related Stigma ’s Association with Anxiety & amp; Depression Among People Living with HIV (PLWH) in Florida
AbstractResearch has shown that HIV-related stigma contributes to people living with HIV having a higher risk of mental health disorders. Our study examines the association between enacted HIV-related stigma and symptoms of anxiety and depression among PLWH. We used baseline data from 932 PLWH collected from the Florida Cohort study between 2014 and 2018. The sample was majority 45  + years of age (63.5%), male (66.0%), and Black (58.1%). The majority had previously experienced enacted HIV-related stigma (53.1%). Additionally, 56.6% and 65.2% showed mild to moderate/severe levels of anxiety and depression, re...
Source: AIDS and Behavior - June 20, 2020 Category: Infectious Diseases Source Type: research

Correction to: Ugandan Study Participants Experience Electronic Monitoring of Antiretroviral Therapy Adherence as Welcomed Pressure to Adhere
The original version of this article unfortunately contained an error. The authors would like to correct the error with this erratum. (Source: AIDS and Behavior)
Source: AIDS and Behavior - June 15, 2020 Category: Infectious Diseases Source Type: research

Presence of Older Adolescents in the Household is Associated with Depressive Symptoms Among Women Living with HIV in Kenya
The objective of this study was to determine the association between the number of adolescents in a household and depressive symptoms among adult caregivers living with HIV. We examined cross-sectional baseline data among adults enrolled in theShamba Maisha multisectoral agricultural intervention (n  = 705) in the Nyanza region of Kenya (NCT02815579). Each additional adolescent 15–19 years in a household was associated with a 1.35 (95% CI 1.06–1.71) higher odds of depressive symptoms among women, but not men, adjusting for potential confounders. Interventions to support the mental heal th of ...
Source: AIDS and Behavior - June 12, 2020 Category: Infectious Diseases Source Type: research

How to Have Sex in an Epidemic Redux: Reinforcing HIV Prevention in the COVID-19 Pandemic
(Source: AIDS and Behavior)
Source: AIDS and Behavior - June 4, 2020 Category: Infectious Diseases Source Type: research

Microenterprise Intervention to Reduce Sexual Risk Behaviors and Increase Employment and HIV Preventive Practices Among Economically-Vulnerable African-American Young Adults (EMERGE): A Feasibility Randomized Clinical Trial
This study assessed the feasibility of conducting a randomized clinical trial of a 20-week microenterprise intervention for economically-vulnerable African-American young adults.EngagingMicroenterprisE forResourceGeneration and HealthEmpowerment (EMERGE) aimed to reduce sexual risk behaviors and increase employment and uptake of HIV preventive behaviors. The experimental group received text messages on job openings plus educational sessions, mentoring, a start-up grant, and business and HIV prevention text messages. The comparison group received text messages on job openings only. Primary feasibility objectives assessed re...
Source: AIDS and Behavior - June 3, 2020 Category: Infectious Diseases Source Type: research

Antiretroviral Adherence, Drug Resistance, and the Impact of Social Determinants of Health in HIV-1 Patients in the US
AbstractAdherence to antiretroviral therapy (ART) is critical to achieving viral suppression. However, social determinants of health (SDoH) can undermine patient adherence to ART, resulting in drug resistance that compromises future treatment options. We assessed ART adherence and HIV-1 drug resistance at the national and state levels in the US and investigated their associations with SDoH and other HIV-related outcomes. Data were obtained from Symphony Health ’s Integrated Dataverse (IDV), Monogram/LabCorp Database, as well as national and publicly available databases, including Centers for Disease Control and Preve...
Source: AIDS and Behavior - June 2, 2020 Category: Infectious Diseases Source Type: research

Impact of the COVID-19 Pandemic on HIV Testing and Assisted Partner Notification Services, Western Kenya
(Source: AIDS and Behavior)
Source: AIDS and Behavior - June 2, 2020 Category: Infectious Diseases Source Type: research

When Home is Not a Safe Place: Impacts of Social Distancing Directives on Women Living with HIV
(Source: AIDS and Behavior)
Source: AIDS and Behavior - June 2, 2020 Category: Infectious Diseases Source Type: research

COVID-19 Lockdowns: Impact on Facility-Based HIV Testing and the Case for the Scaling Up of Home-Based Testing Services in Sub-Saharan Africa
(Source: AIDS and Behavior)
Source: AIDS and Behavior - June 2, 2020 Category: Infectious Diseases Source Type: research

Motivation to Quit Drinking in Individuals Coinfected with HIV and Hepatitis C
This study identified several factors associated with motivation to quit drinking in a sample of alcohol-consuming HIV/HCV patients. (Source: AIDS and Behavior)
Source: AIDS and Behavior - May 13, 2020 Category: Infectious Diseases Source Type: research

Alcohol Use and Antiretroviral Therapy Non-Adherence Among Adults Living with HIV/AIDS in Sub-Saharan Africa: A Systematic Review and Meta-Analysis
AbstractAntiretroviral therapy (ART) is efficacious in improving clinical outcomes among people living with HIV (PLWH) and reducing HIV transmission when taken regularly. Research examining modifiable factors associated with ART non-adherence is critical for informing novel intervention development in settings with high HIV prevalence. Alcohol use has been linked with ART non-adherence in studies in sub-Saharan Africa; however, no review has pooled estimates across studies. We reviewed studies of alcohol use and ART non-adherence conducted in sub-Saharan Africa. We searched PubMed, CINAHL, EMBASE, and PsycINFO through Augu...
Source: AIDS and Behavior - May 13, 2020 Category: Infectious Diseases Source Type: research

Burden of Depression in Outpatient HIV-Infected adults in Sub-Saharan Africa; Systematic Review and Meta-analysis
AbstractDespite the substantial burden of HIV in Africa, and the knowledge that depression causes worse HIV outcomes, the burden of depression in people living with HIV in Africa is unknown. We searched Pubmed and four other databases using key terms: depression, Africa, HIV, and prevalence from 2008 to 2018. We summarized depression prevalence by country. We estimated the burden of depression using our prevalence data and 2018 UNAIDS HIV estimates. Our search yielded 70 articles across 16 African countries. The overall prevalence of major depression in those HIV-infected using a diagnostic interview was 15.3% (95% CI 12.5...
Source: AIDS and Behavior - May 13, 2020 Category: Infectious Diseases Source Type: research

Depressive Symptom Trajectories Among People Living with HIV in a Collaborative Care Program
AbstractDepressive symptoms may differ in severity and change over time in people living with HIV (PLWH). Describing depression trajectories and associated clinical characteristics of PLWH in an interventional study may help in developing a more personalized medicine approach. Using latent class growth analysis four, 15-month self-reported depression trajectories were identified in 416 PLWH participating in a collaborative care program. The four subgroups were characterized by improving (58.4% [of participants]), worsening (9.4%), highly responsive (19.5%) and persistently severe (12.7%) depressive symptoms. A high proport...
Source: AIDS and Behavior - May 13, 2020 Category: Infectious Diseases Source Type: research

Fertility Intentions and Clinical Care Attendance Among Women Living with HIV in South Africa
AbstractPoor HIV care retention impedes optimal treatment outcomes in persons living with HIV. Women trying to become pregnant may be motivated by periconception horizontal and vertical transmission concerns and thus more likely to attend HIV care visits than women not trying to conceive. We estimated the effect of fertility intentions on HIV care attendance over 12  months among non-pregnant, HIV-positive women aged 18–35 years who were on or initiating antiretroviral therapy in Johannesburg, South Africa. The percentage of women attending an HIV care visit decreased from 93.4% in the first quarter to 82.8...
Source: AIDS and Behavior - May 13, 2020 Category: Infectious Diseases Source Type: research

Effect of FAmily CEntered (FACE ®) Advance Care Planning on Longitudinal Congruence in End-of-Life Treatment Preferences: A Randomized Clinical Trial
AbstractTrial tested effect of advance care planning on family/surrogates ’ understanding of patients’ end-of-life treatment preferences longitudinally. A multisite, assessor-blinded, intent-to-treat, parallel-group, randomized controlled clinical trial in five hospital-based HIV clinics enrolled 449 participants aged 22 to 77 years during October 2013-March 2017. Pa tients living with HIV/family dyads were randomized at 2:1 ratio to 2 weekly ~ 60-min sessions either ACP (n = 155 dyads)—(1) ACP facilitated conversation, (2) Advance directive completion; or Control (n&thins...
Source: AIDS and Behavior - May 12, 2020 Category: Infectious Diseases Source Type: research

Confronting Another Pandemic: Lessons from HIV can Inform Our COVID-19 Response
AbstractThe novel coronavirus 2019 illness (COVID-19) has completely transformed and uprooted lives across the globe. While different diseases, there are critical observations and lessons to be learned from the ongoing HIV epidemic to inform our response to COVID-19. We reflect on how this relates to (1) testing, including contact tracing; (2) health system redesign; (3) telehealth; (4) health disparities; (5) political denial, with inadequate and uncoordinated governmental response; (6) occupational exposure; and (7) complex reactions among healthcare providers. Decades of experiences with HIV provide an important framewo...
Source: AIDS and Behavior - May 12, 2020 Category: Infectious Diseases Source Type: research

Conceptualizing LGBT Stigma and Associated HIV Vulnerabilities Among LGBT Persons in Lesotho
AbstractSocial marginalization harms lesbian, gay, bisexual, and transgender (LGBT) persons ’ wellbeing in Lesotho. Socio-cultural mechanisms linking LGBT stigma, depression, substance use, and HIV among LGBT persons in Lesotho are understudied. We explore associations between LGBT stigma, mental health stressors, and HIV vulnerabilities among LGBT persons in Lesotho. We conducted in-dep th, semi-structured interviews with 46 LGBT persons and six key informants (e.g. healthcare providers). Participants described depression, substance use, and HIV as mutually reinforcing and situated in larger social contexts of stigm...
Source: AIDS and Behavior - May 11, 2020 Category: Infectious Diseases Source Type: research

Psychosocial Factors, Condomless Sex, and Detectable Viral Load in HIV-Positive Women in Serodiscordant Couples in Nairobi, Kenya
AbstractThis prospective study of HIV-positive Kenyan women in serodiscordant couples examined relationships between  psychosocial factors, viral suppression, and condomless sex. Participants were screened for alcohol use disorders and intimate partner violence (IPV) annually and depressive symptoms every 6 months. Prostate specific antigen (PSA) detection was used as a marker for condomless sex. A total of 151 participants contributed 349 person-years of follow-up. Hazardous/harmful alcohol use was associated with increased risk of detecting PSA in vaginal secretions (aRR 1.99, 95%CI 1.08–3.66, χ2&thin...
Source: AIDS and Behavior - May 11, 2020 Category: Infectious Diseases Source Type: research

Individual and Social Network Structure Characteristics Associated with Peer Change Agent Engagement and Impact in a PrEP Intervention
AbstractInterventions that utilize the influence of peer change agents (PCAs) have been shown to be effective strategies for engaging key populations in HIV prevention. To date, little is known about the characteristics of PCAs associated with their effectiveness. Drawing on data from a peer leader PrEP intervention for young Black men who have sex with men (YBMSM) (N  = 423), we evaluated the effects of experiential (i.e., living with HIV, PrEP awareness, PrEP use), psychographic (i.e., self-perceived leadership, innovativeness), and network (i.e., degree centrality, eigenvector centrality, and brokerage) ch...
Source: AIDS and Behavior - May 11, 2020 Category: Infectious Diseases Source Type: research

“It’s Like Plan B but for HIV!” Design and Evaluation of a Media Campaign to Drive Demand for PEP
AbstractPost-exposure Prophylaxis (PEP) is an effective yet underutilized HIV prevention tool. PEPTALK developed and evaluated a media campaign to drive demand for PEP among men who have sex with men (MSM) and transgender women (TW) living in high HIV prevalence areas in New York City. Formative qualitative research (38 in-depth interviews and five focus groups [N  = 48]) with Black or African-American MSM or TW who reported condomless sex with a HIV-positive/unknown status man was conducted to inform campaign design. We assessed the impact of the campaign, 15 bus shelter ads and low or no-cost social media, ...
Source: AIDS and Behavior - May 10, 2020 Category: Infectious Diseases Source Type: research

“Keep It Going if You Can”: HIV Service Provision for Priority Populations During the COVID-19 Pandemic in Seattle, WA
(Source: AIDS and Behavior)
Source: AIDS and Behavior - May 8, 2020 Category: Infectious Diseases Source Type: research

Adherence to Pre-exposure Prophylaxis in Black Men Who Have Sex with Men and Transgender Women in a Community Setting in Harlem, NY
AbstractWhile oral pre-exposure prophylaxis (PrEP) has proven efficacious for HIV prevention, consistent use is necessary to achieve its intended impact. We compared effectiveness of enhanced PrEP (enPrEP) adherence support to standard of care (sPrEP) among Black MSM and TGW attending a community clinic in Harlem, NY. EnPrEP included peer navigation, in-person/online support groups, and SMS messages. Self-reported adherence over previous 30  days, collected in quarterly interviews, was defined as ≥ 57%. Crude and adjusted analyses examined factors associated with adherence. A total of 204 participants...
Source: AIDS and Behavior - May 8, 2020 Category: Infectious Diseases Source Type: research

HIV and Food Insecurity: A Syndemic Amid the COVID-19 Pandemic
(Source: AIDS and Behavior)
Source: AIDS and Behavior - May 8, 2020 Category: Infectious Diseases Source Type: research

Using an HIV Self-test Kit to Test a Partner: Attitudes and Preferences Among High-Risk Populations
AbstractFor those most at risk of contracting HIV, new strategies for preventing transmission and increasing testing are needed. As part of a multi-site, randomized, controlled trial, we explored attitudes and preferences among 272 HIV-negative men who have sex with men and HIV-negative transgender women using an HIV self-testing (HIVST) kit to test partners. Less than one quarter had previously self-tested with HIVST kits (21.7%) and few had partner-tested (4.8%). Most preferred gum swab (96%) over fingerprick tests (69%), but would prefer a blood test if it gave results for other sexually transmitted infections (STIs) (8...
Source: AIDS and Behavior - May 8, 2020 Category: Infectious Diseases Source Type: research

Challenges to HIV Care and Psychological Health During the COVID-19 Pandemic Among People Living with HIV in China
(Source: AIDS and Behavior)
Source: AIDS and Behavior - May 7, 2020 Category: Infectious Diseases Source Type: research

HIV Care Continuum and COVID-19 Outcomes Among People Living with HIV During the COVID-19 Pandemic, Chicago, IL
(Source: AIDS and Behavior)
Source: AIDS and Behavior - May 7, 2020 Category: Infectious Diseases Source Type: research

Routine Screening for HIV in an Urban Emergency Department During the COVID-19 Pandemic
(Source: AIDS and Behavior)
Source: AIDS and Behavior - May 2, 2020 Category: Infectious Diseases Source Type: research

Assessing HIV-Related Stigma in Healthcare Settings in the Era of the COVID-19 Pandemic, Pittsburgh, Pennsylvania
(Source: AIDS and Behavior)
Source: AIDS and Behavior - May 2, 2020 Category: Infectious Diseases Source Type: research

The Unanticipated Benefits of PrEP for Young Black Gay, Bisexual, and Other Men Who Have Sex with Men
AbstractPre-exposure prophylaxis (PrEP) is effective at reducing new HIV infections among adherent users. However, there are potential benefits of PrEP beyond HIV prevention that remain understudied, particularly among young Black gay, bisexual, and other men who have sex with men (MSM). In 2018, we conducted six focus groups (n  = 36) in four midwestern cities: Milwaukee, WI; Minneapolis, MN; Detroit, MI; and Kansas City, MO with current and former PrEP users who identified as Black MSM. The focus groups covered medical care and provider experiences, patterns of PrEP use and adherence, relationships while on...
Source: AIDS and Behavior - April 15, 2020 Category: Infectious Diseases Source Type: research

Gay Men ’s Relationship Agreements in the Era of Pre-exposure Prophylaxis: An Analysis of Australian Behavioural Surveillance Data
AbstractUsing repeated, cross-sectional behavioural surveillance data from Australia, we assessed trends in relationship agreements and casual sex among HIV-negative and untested gay and bisexual men who had regular partners during 2013 –2018. We conducted three analyses: (i) trends in relationship agreements and casual sex over time; (ii) bivariate comparisons of PrEP users and non-PrEP-users to identify factors associated with PrEP use; and (iii) multivariate logistic regression to identify factors independently associated with PrEP use. The analysis of trends over time included 21,593 men, from which a sub-sample ...
Source: AIDS and Behavior - April 15, 2020 Category: Infectious Diseases Source Type: research

Project Moxie: Results of a Feasibility Study of a Telehealth Intervention to Increase HIV Testing Among Binary and Nonbinary Transgender Youth
AbstractTransgender youth have low rates of engagement in HIV prevention, shaped in part by experiences of transphobia and lack of access to culturally competent care. Project Moxie tested the feasibility of an intervention that provides home-based HIV self-testing coupled with video-chat counseling. A diverse sample of 202 binary and nonbinary transgender youth (TY) were recruited online, and randomized 2:1 to receive the intervention or a control condition of only home-based HIV self-testing. TY were willing to order HIV self-testing kits and report their results. Half of those in the intervention arm opted to use the vi...
Source: AIDS and Behavior - April 15, 2020 Category: Infectious Diseases Source Type: research

Biomedical HIV Protection Among Gay and Bisexual Men Who Use Crystal Methamphetamine
AbstractUse of crystal methamphetamine (crystal) among gay and bisexual men (GBM) has been associated with condomless anal intercourse with casual partners (CLAIC) and HIV infection. Pre-exposure prophylaxis (PrEP) and undetectable viral load (UVL) are important biomedical HIV prevention strategies. We investigate the relationship between crystal use and HIV sexual risk behaviours in the context of PrEP and UVL. In 2018, 1367 GBM provided details about crystal use and HIV prevention strategies. Binary logistic regression was used to estimate associations between crystal use and behaviour. Recent crystal use was independent...
Source: AIDS and Behavior - April 15, 2020 Category: Infectious Diseases Source Type: research

Intimate Partner Violence and Pre-exposure Prophylaxis (PrEP): A Rapid Review of Current Evidence for Women ’s HIV Prevention
AbstractPre-exposure prophylaxis (PrEP) is a valued component of HIV prevention and increasing attention is focusing on women ’s PrEP use. Common HIV prevention options (e.g., condoms) remain underused and fail to consider the context of intimate partner violence (IPV). PrEP presents an opportunity to expand viable options for women. A systematic rapid review using key word searches of PubMed and proceedings from six nat ional and international conferences related to HIV, women’s health, or interpersonal violence identified nine studies which met set inclusion criteria. Studies were coded using a structured abs...
Source: AIDS and Behavior - April 15, 2020 Category: Infectious Diseases Source Type: research

Associations Between Relationship Power and Pre-Exposure Prophylaxis (PrEP) Use Among Men Who Have Sex With Men
This study examined associations between relationship power and PrEP use among 826 MSM participating in a cross-sectional, Internet-based survey. The results of our analysis indicate that decision-making dominance was positively associated with PrEP use among MSM, but the association between relationship control/overall relationship power and PrEP use was inconclusive. Furthermore, when examining specific types of decision-making dominance, equal and greater dominance compared to one ’s partner regarding types of sexual activity engaged in, as well as dominance more generally, were positively associated with PrEP use...
Source: AIDS and Behavior - April 15, 2020 Category: Infectious Diseases Source Type: research