Availability of genome-matched therapy based on clinical practice
CONCLUSION: This study demonstrated the usefulness of CGP for patients with sarcoma and HNC in addition to lung cancer in clinical practice. Performing CGP at the front line has the potential to improve the availability of genome-matched therapy.PMID:38668785 | DOI:10.1007/s10147-024-02533-z (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - April 26, 2024 Category: Cancer & Oncology Authors: Naomi Hayashi Seiichi Mori Akihiro Ohmoto Ippei Fukada Masumi Yamazaki Mari Hosonaga Xiaofei Wang Arisa Ueki Kazuma Kiyotani Akiko Tonooka Kengo Takeuchi Shunji Takahashi Source Type: research

Availability of genome-matched therapy based on clinical practice
CONCLUSION: This study demonstrated the usefulness of CGP for patients with sarcoma and HNC in addition to lung cancer in clinical practice. Performing CGP at the front line has the potential to improve the availability of genome-matched therapy.PMID:38668785 | DOI:10.1007/s10147-024-02533-z (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - April 26, 2024 Category: Cancer & Oncology Authors: Naomi Hayashi Seiichi Mori Akihiro Ohmoto Ippei Fukada Masumi Yamazaki Mari Hosonaga Xiaofei Wang Arisa Ueki Kazuma Kiyotani Akiko Tonooka Kengo Takeuchi Shunji Takahashi Source Type: research

Interdisciplinary Collaboration in Head and Neck Cancer Care: Optimizing Oral Health Management for Patients Undergoing Radiation Therapy
In conclusion, these proactive measures help minimize dental and oral complications before, during, and after treatment.PMID:38668058 | PMC:PMC11049200 | DOI:10.3390/curroncol31040155 (Source: Current Oncology)
Source: Current Oncology - April 26, 2024 Category: Cancer & Oncology Authors: Tugce Kutuk Ece Atak Alessandro Villa Noah S Kalman Adeel Kaiser Source Type: research

Availability of genome-matched therapy based on clinical practice
CONCLUSION: This study demonstrated the usefulness of CGP for patients with sarcoma and HNC in addition to lung cancer in clinical practice. Performing CGP at the front line has the potential to improve the availability of genome-matched therapy.PMID:38668785 | DOI:10.1007/s10147-024-02533-z (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - April 26, 2024 Category: Cancer & Oncology Authors: Naomi Hayashi Seiichi Mori Akihiro Ohmoto Ippei Fukada Masumi Yamazaki Mari Hosonaga Xiaofei Wang Arisa Ueki Kazuma Kiyotani Akiko Tonooka Kengo Takeuchi Shunji Takahashi Source Type: research

Availability of genome-matched therapy based on clinical practice
CONCLUSION: This study demonstrated the usefulness of CGP for patients with sarcoma and HNC in addition to lung cancer in clinical practice. Performing CGP at the front line has the potential to improve the availability of genome-matched therapy.PMID:38668785 | DOI:10.1007/s10147-024-02533-z (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - April 26, 2024 Category: Cancer & Oncology Authors: Naomi Hayashi Seiichi Mori Akihiro Ohmoto Ippei Fukada Masumi Yamazaki Mari Hosonaga Xiaofei Wang Arisa Ueki Kazuma Kiyotani Akiko Tonooka Kengo Takeuchi Shunji Takahashi Source Type: research

Availability of genome-matched therapy based on clinical practice
CONCLUSION: This study demonstrated the usefulness of CGP for patients with sarcoma and HNC in addition to lung cancer in clinical practice. Performing CGP at the front line has the potential to improve the availability of genome-matched therapy.PMID:38668785 | DOI:10.1007/s10147-024-02533-z (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 26, 2024 Category: Cancer & Oncology Authors: Naomi Hayashi Seiichi Mori Akihiro Ohmoto Ippei Fukada Masumi Yamazaki Mari Hosonaga Xiaofei Wang Arisa Ueki Kazuma Kiyotani Akiko Tonooka Kengo Takeuchi Shunji Takahashi Source Type: research

Interdisciplinary Collaboration in Head and Neck Cancer Care: Optimizing Oral Health Management for Patients Undergoing Radiation Therapy
In conclusion, these proactive measures help minimize dental and oral complications before, during, and after treatment.PMID:38668058 | PMC:PMC11049200 | DOI:10.3390/curroncol31040155 (Source: Current Oncology)
Source: Current Oncology - April 26, 2024 Category: Cancer & Oncology Authors: Tugce Kutuk Ece Atak Alessandro Villa Noah S Kalman Adeel Kaiser Source Type: research

Potential Single Nucleotide Polymorphisms markers for radiation dermatitis in head and neck cancer patients: a  meta-analysis
ConclusionThe most prevalent SNPs may be predictors of acute RD. The analysis of SNP before starting radiation therapy may be a  promising method to predict the risk of developing radiation dermatitis and allow radiosensitive patients to have a customized treatment. This current review provides new research directions. (Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - April 26, 2024 Category: Cancer & Oncology Source Type: research

Intratumoral therapies in head and neck squamous cell carcinoma: A systematic review and future perspectives
Head and neck squamous cell carcinoma (HNSCC) constitute a diverse category of cancer sites, encompassing oral cavity, pharynx, larynx, nasal cavity, and paranasal sinuses [1].These malignancies represent a significant global health challenge, affecting countries at various levels of development. According to data from The Global Cancer Observatory (GLOBOCAN) in 2020, HNSCC ranked as the seventh most common cancer worldwide [2]. Projections for 2030 predict an alarming global rise, primarily driven by tumors associated with the human papillomavirus (HPV)[1]. (Source: Cancer Treatment Reviews)
Source: Cancer Treatment Reviews - April 26, 2024 Category: Cancer & Oncology Authors: Pablo Jim énez-Labaig, Antonio Rullan, Irene Braña, Alberto Hernando-Calvo, Victor Moreno, Bernard Doger, George Bitar, Derfel Ap Dafydd, Alan Melcher, Kevin J. Harrington Tags: Anti-tumour Treatment Source Type: research

Availability of genome-matched therapy based on clinical practice
ConclusionThis study demonstrated the usefulness of CGP for patients with sarcoma and HNC in addition to lung cancer in clinical practice. Performing CGP at the front line has the potential to improve the availability of genome-matched therapy. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - April 26, 2024 Category: Cancer & Oncology Source Type: research

Medical students' knowledge about human papillomavirus (HPV), HPV vaccine and head and neck cancer
Hum Vaccin Immunother. 2024 Dec 31;20(1):2344248. doi: 10.1080/21645515.2024.2344248. Epub 2024 Apr 24.ABSTRACTThe Human Papillomavirus (HPV) is a sexually transmitted infection that significantly affects the population worldwide. HPV preventive methods include vaccination, prophylactics, and education. Different types of cancers associated with HPV usually take years or decades to develop after infections, such as Head and Neck Cancer(HNC). Therefore, HPV prevention can be considered cancer prevention. A sample of medical students in Puerto Rico was evaluated to assess their knowledge about HPV, HPV vaccine, and HNC throu...
Source: Cancer Control - April 25, 2024 Category: Cancer & Oncology Authors: Norangelys Solis-Torres Isardo Braverman-Diaz Luis A Rivera-Morales Jose J Perez-Sanchez Valeria S Perez-Bravo Angel J Neris-Sanchez Alexis Vera Yaritza Diaz-Algorri Source Type: research

PLAU promotes cell proliferation and migration of head and neck cancer via STAT3 signaling pathway
Exp Cell Res. 2024 Apr 23:114056. doi: 10.1016/j.yexcr.2024.114056. Online ahead of print.ABSTRACTIt was reported that within the head and neck cancer (HNC) cell line CAL21 the epithelial-mesenchymal transition (EMT) and cell proliferation were promoted by Urokinase-Type Plasminogen Activator (PLAU) proteinase through TNFRSF12A. Additionally, in this paper HNC cell lines refer to Fadu and Tu686. A novel PLAU-STAT3 axis was found to be involved in HNC cell line proliferation and metastasis. PLAU expression in HNC samples was upregulated, besides, the elevated expression of PLAU was linked to the lower overall survival (OS) ...
Source: Experimental Cell Research - April 25, 2024 Category: Cytology Authors: Xiaobo Cui Hongyang Sun Xiaoqing Liu Yunfei Bai Yanping Bai Yanru Cui Boqian Wang Shu Zhang Xin Li Source Type: research

PLAU promotes cell proliferation and migration of head and neck cancer via STAT3 signaling pathway
Exp Cell Res. 2024 Apr 23:114056. doi: 10.1016/j.yexcr.2024.114056. Online ahead of print.ABSTRACTIt was reported that within the head and neck cancer (HNC) cell line CAL21 the epithelial-mesenchymal transition (EMT) and cell proliferation were promoted by Urokinase-Type Plasminogen Activator (PLAU) proteinase through TNFRSF12A. Additionally, in this paper HNC cell lines refer to Fadu and Tu686. A novel PLAU-STAT3 axis was found to be involved in HNC cell line proliferation and metastasis. PLAU expression in HNC samples was upregulated, besides, the elevated expression of PLAU was linked to the lower overall survival (OS) ...
Source: Cell Research - April 25, 2024 Category: Cytology Authors: Xiaobo Cui Hongyang Sun Xiaoqing Liu Yunfei Bai Yanping Bai Yanru Cui Boqian Wang Shu Zhang Xin Li Source Type: research