Biplex quantitative PCR to detect transcriptionally active human papillomavirus 16 from patient saliva
Head and neck cancers, particularly oropharyngeal cancers (OPC), have been increasingly associated with human papillomavirus (HPV) infections, specifically HPV16. The current methods for HPV16 detection primar... (Source: BMC Cancer)
Source: BMC Cancer - April 10, 2024 Category: Cancer & Oncology Authors: Fiona Deutsch, Dayna Sais, Ni Keatinge, Meredith Hill, Ngoc Ha Tran, Michael Elliott and Nham Tran Tags: Research Source Type: research
Identification of stemness-related glycosylation changes in head and neck squamous cell carcinoma
In this study, we investigated the glycosylation profile of stemness-related proteins OCT4, CIP2A, MET, and ... (Source: BMC Cancer)
Source: BMC Cancer - April 10, 2024 Category: Cancer & Oncology Authors: E Routila, R Mahran, S Salminen, H Irjala, E Haapio, E Kyt ö, S Ventelä, K Petterson, J Routila, K Gidwani and J Leivo Tags: Research Source Type: research
Cancers, Vol. 16, Pages 1457: A Systematic Review and Meta-Analysis of 29 Studies Predicting Diagnostic Accuracy of CT, MRI, PET, and USG in Detecting Extracapsular Spread in Head and Neck Cancers
Conclusion: MRI is the most accurate imaging modality for detecting ECS in head and neck cancers. CT scan is a reasonable alternative, but PET scan may be considered when high specificity is required. USG may not add any further benefit in detecting ECS. (Source: Cancers)
Source: Cancers - April 10, 2024 Category: Cancer & Oncology Authors: Manish Mair Hitesh Singhavi Ameya Pai Mariya Khan Peter Conboy Oladejo Olaleye Rami Salha Phil Ameerally Ram Vaidhyanath Pankaj Chaturvedi Tags: Systematic Review Source Type: research
Esophageal Dysphagia in Adults
This article underscores the role of detailed patient history and physical examinations, including prompt endoscopic evaluation, for accurate differentiation between esophageal and oropharyngeal dysphagia. The authors discuss the heightened importance of early intervention in certain patient groups, such as elderly individuals and patients with head and neck cancer, to mitigate the risk of malnutrition and infection. The authors delve into etiologic factors highlighting the complexity of clinical presentations and the significance of tailored management strategies. (Source: Otolaryngologic clinics of North America)
Source: Otolaryngologic clinics of North America - April 10, 2024 Category: ENT & OMF Authors: Miller Richmond, Elliana Kirsh DeVore, Phillip C. Song Source Type: research
Advances and residual knowledge gaps in the neck management of head and neck squamous cell carcinoma patients with advanced nodal disease undergoing definitive (chemo)radiotherapy for their primary
ConclusionPersonalized neck management is an increasingly important aspect of the overall therapeutic strategies in cN+ HNSCC.Graphic abstract (Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - April 10, 2024 Category: Cancer & Oncology Source Type: research
Higher overall survival rates of oral squamous cell carcinoma treated with metronomic neoadjuvant chemotherapy
Am J Cancer Res. 2024 Mar 15;14(3):1033-1051. doi: 10.62347/EYNT8387. eCollection 2024.ABSTRACTDistant metastasis is an important prognostic factor for oral squamous cell carcinoma (OSCC). It involves the direct spread of tumor cells through blood vessels or via lymph nodes; however, there are currently no well-established treatments for its prevention in patients with OSCC. To investigate the impact of metronomic neoadjuvant chemotherapy on OSCC, we conducted a retrospective analysis of the efficacy of neoadjuvant chemotherapy with S-1 alone. Fifty-four patients underwent up-front surgery, while 106 received neoadjuvant c...
Source: Cell Research - April 9, 2024 Category: Cytology Authors: Shinichiro Kina Sho Miyamoto Reika Kawabata-Iwakawa Mika Kina-Tanada Masaru Ogawa Satoshi Yokoo Source Type: research
Stereotactic ablative radiotherapy for treating primary head and neck cancer and locoregional recurrence: A comprehensive review of the literature
CONCLUSIONS: SABR is an innovative, effective and promising treatment modality for small targets, especially in near proximity to organs at risk or in a pre-irradiated region. Prospective trials are further needed for this technique to become standard-of care.PMID:38590327 | PMC:PMC10999469 | DOI:10.1016/j.ctro.2024.100766 (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - April 9, 2024 Category: Cancer & Oncology Authors: Ciro Franzese Panagiotis Balermpas Source Type: research
BAF-Net: bidirectional attention-aware fluid pyramid feature integrated multimodal fusion network for diagnosis and prognosis
Phys Med Biol. 2024 Apr 9. doi: 10.1088/1361-6560/ad3cb2. Online ahead of print.ABSTRACTTo go beyond the deficiencies of the three conventional multimodal fusion strategies (i.e., input-, feature- and output-level fusion), we propose a bidirectional attention-aware fluid pyramid feature integrated fusion network (BAF-Net) with cross-modal interactions for multimodal medical image diagnosis and prognosis.
Approach: BAF-Net is composed of two identical branches to preserve the unimodal features and one bidirectional attention-aware distillation stream to progressively assimilate cross-modal complements and to learn s...
Source: Physics in Medicine and Biology - April 9, 2024 Category: Physics Authors: Huiqin Wu Lihong Peng Dongyang Du Hui Xu Guoyu Lin Zidong Zhou Lijun Lu Wenbing Lv Source Type: research
Stereotactic ablative radiotherapy for treating primary head and neck cancer and locoregional recurrence: A comprehensive review of the literature
CONCLUSIONS: SABR is an innovative, effective and promising treatment modality for small targets, especially in near proximity to organs at risk or in a pre-irradiated region. Prospective trials are further needed for this technique to become standard-of care.PMID:38590327 | PMC:PMC10999469 | DOI:10.1016/j.ctro.2024.100766 (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - April 9, 2024 Category: Cancer & Oncology Authors: Ciro Franzese Panagiotis Balermpas Source Type: research
