Pulse parameter optimizer: an efficient tool for achieving prescribed dose and dose rate with electron FLASH platforms
Conclusion. A pulse parameter optimization application was built for a commercial electron FLASH platform to increase efficiency in dose, dose rate, and pulse parameter prescription process. Automating this process reduces safety concerns associated with manual look up and calculation of these parameters, especially when many subjects at different doses and dose rates are to be safely managed.PMID:37735967 | DOI:10.1088/1361-6560/acf63e (Source: Physics in Medicine and Biology)
Source: Physics in Medicine and Biology - September 22, 2023 Category: Physics Authors: S Jain A Cetnar J Woollard N Gupta D Blakaj A Chakravarti A S Ayan Source Type: research
Large-view x-ray imaging for medical applications using the world's only vertically polarized synchrotron radiation beam and a single asymmetric Si crystal
Phys Med Biol. 2023 Sep 22;68(19). doi: 10.1088/1361-6560/acf640.ABSTRACTObjective.X-ray microangiography provides detailed information on the internal structure and function of a biological subject. Its ability to evaluate the microvasculature of small animals is useful for acquiring basic and clinical medical knowledge. The following three conditions are necessary to attain detailed knowledge of biological functions: (1) high temporal resolution with sufficient x-ray intensity, (2) high spatial resolution, and (3) a wide field of view. Because synchrotron radiation microangiography systems provide high sapatial resolutio...
Source: Physics in Medicine and Biology - September 22, 2023 Category: Physics Authors: Chika Kamezawa Kazuyuki Hyodo Chiho Tokunaga Toru Tsukada Shonosuke Matushita Source Type: research
Dose distribution estimation toward CT-less adaptive carbon ion radiotherapy for liver tumors using the divided-volume matching technique
This study aims to investigate the feasibility of evaluating daily dose distributions using the divided-volume matching (DVM) technique without additional daily computed tomography (CT) scans for adaptive carbon ion radiotherapy for liver tumors. 
Approach
Phantom and patient data were included in this study. The developed in-house DVM software generated DVM CTs based on the existing resources, the planning CT, and orthogonal two-dimensional (2D) setup images. Bone matching (BM) and tumor matching (TM) are the two common ways of patient positioning correction to determine the isocenter for the irradiation o...
Source: Physics in Medicine and Biology - September 22, 2023 Category: Physics Authors: Jing-Ni Chen Tatsuya Ohno Mutsumi Tashiro Source Type: research
Operational Ontology for Oncology: A Framework for Improved Communication and Understanding in Cancer Care
Int J Radiat Oncol Biol Phys. 2023 Nov 1;117(3):551-553. doi: 10.1016/j.ijrobp.2023.02.058.NO ABSTRACTPMID:37739606 | DOI:10.1016/j.ijrobp.2023.02.058 (Source: Physics in Medicine and Biology)
Source: Physics in Medicine and Biology - September 22, 2023 Category: Physics Authors: David S Hong Amanda Caissie Coen W Hurkmans Andra V Krauze Randi Kudner Thomas G Purdie Ying Xiao Source Type: research
Pulse parameter optimizer: an efficient tool for achieving prescribed dose and dose rate with electron FLASH platforms
Conclusion. A pulse parameter optimization application was built for a commercial electron FLASH platform to increase efficiency in dose, dose rate, and pulse parameter prescription process. Automating this process reduces safety concerns associated with manual look up and calculation of these parameters, especially when many subjects at different doses and dose rates are to be safely managed.PMID:37735967 | DOI:10.1088/1361-6560/acf63e (Source: Physics in Medicine and Biology)
Source: Physics in Medicine and Biology - September 22, 2023 Category: Physics Authors: S Jain A Cetnar J Woollard N Gupta D Blakaj A Chakravarti A S Ayan Source Type: research
Large-view x-ray imaging for medical applications using the world's only vertically polarized synchrotron radiation beam and a single asymmetric Si crystal
Phys Med Biol. 2023 Sep 22;68(19). doi: 10.1088/1361-6560/acf640.ABSTRACTObjective.X-ray microangiography provides detailed information on the internal structure and function of a biological subject. Its ability to evaluate the microvasculature of small animals is useful for acquiring basic and clinical medical knowledge. The following three conditions are necessary to attain detailed knowledge of biological functions: (1) high temporal resolution with sufficient x-ray intensity, (2) high spatial resolution, and (3) a wide field of view. Because synchrotron radiation microangiography systems provide high sapatial resolutio...
Source: Physics in Medicine and Biology - September 22, 2023 Category: Physics Authors: Chika Kamezawa Kazuyuki Hyodo Chiho Tokunaga Toru Tsukada Shonosuke Matushita Source Type: research
3D phantom for image quality assessment of mammography systems
Phys Med Biol. 2023 Sep 21. doi: 10.1088/1361-6560/acfc10. Online ahead of print.ABSTRACTOBJECTIVE: To present an innovative approach for the design of a 3D mammographic phantom for medical equipment quality assessment, estimation of the glandular tissue percentage in the patient's breast, and emulation of microcalcification ($\mu$C) breast lesions.APPROACH: Contrast-to noise ratio (CNR) measurements, as well as spatial resolution and intensity-to-glandularity calibrations under mammography conditions were performed to assess the effectiveness of the phantom. CNR measurements were applied to different groups of calcium hyd...
Source: Physics in Medicine and Biology - September 21, 2023 Category: Physics Authors: Jes ús David Bermúdez Sánchez Gerardo Alfonso Roque Juan Sebasti án Calderón García Paula Andrea Pardo Ramos Manuel Fernando S ánchez Alarcón Victor Alfonso Ramos Correa Carlos Arturo Ávila Bernal Source Type: research
Reducing the risk of hallucinations with interpretable deep learning models for low-dose CT denoising: comparative performance analysis
In this study, we aim to use qualitative reader studies and quantitative radiomics studies to assess the perceived quality, signal preservation and statistical feature preservation of LDCT volumes denoised by deep learning. We aim to compare interpretable deep learning methods with classical deep neural networks in clinical de-
noising performance.
Approach: We conducted an image quality analysis (IQA) study to assess the image quality of the denoised volumes based on four criteria to assess the perceived image quality. We subsequently conduct a lesion detection/segmentation study to assess the impact of de...
Source: Physics in Medicine and Biology - September 21, 2023 Category: Physics Authors: Mayank Patwari Ralf Gutjahr Roy Marcus Yannick Thali Adria Font Calvarons Rainer Raupach Andreas Maier Source Type: research
Sub-second whole brain T < sub > 2 < /sub > mapping via multiband SENSE multiple overlapping-echo detachment imaging and deep learning
Phys Med Biol. 2023 Sep 19. doi: 10.1088/1361-6560/acfb71. Online ahead of print.ABSTRACTObjective.Most quantitative magnetic resonance imaging (qMRI) methods are time-consuming. Multiple overlapping-echo detachment (MOLED) imaging can achieve quantitative parametric mapping of a single slice within around one hundred milliseconds. Nevertheless, imaging the whole brain, which involves multiple slices, still takes a few seconds. To further accelerate qMRI, we introduce multiband SENSE (MB-SENSE) technology to MOLED to realize simultaneous multi-slice T2mapping.
Approach.The multiband MOLED (MB-MOLED) pulse sequence ...
Source: Physics in Medicine and Biology - September 19, 2023 Category: Physics Authors: Simin Li Taishan Kang Jian Wu Weikun Chen Qing Lin Zhigang Wu Jiazheng Wang Congbo Cai Shuhui Cai Source Type: research
Point-of-care AI-assisted stepwise ultrasound pneumothorax diagnosis
Phys Med Biol. 2023 Sep 19. doi: 10.1088/1361-6560/acfb70. Online ahead of print.ABSTRACTUltrasound is extensively utilized as a convenient and costeffective method in emergency situations. Unfortunately, the limited availability of skilled clinicians in emergency hinders the wider adoption of point-of-care ultrasound. To overcome this challenge, this paper aims to aid less experienced healthcare providers in emergency lung ultrasound scans.
Approach: To assist healthcare providers, it is important to have a comprehensive model that can automatically guide the entire process of lung ultrasound based on the clinicia...
Source: Physics in Medicine and Biology - September 19, 2023 Category: Physics Authors: Kyungsang Kim Fabiola Macruz Dufan Wu Christopher Bridge Suzannah McKinney Ahad Alhassan Al Saud Elshaimaa Sharaf Adam Pely Paul Danset Tom Duffy Davin Dhatt Varun Buch Andrew Liteplo Quanzheng Li Source Type: research
Sub-second whole brain T < sub > 2 < /sub > mapping via multiband SENSE multiple overlapping-echo detachment imaging and deep learning
Phys Med Biol. 2023 Sep 19. doi: 10.1088/1361-6560/acfb71. Online ahead of print.ABSTRACTObjective.Most quantitative magnetic resonance imaging (qMRI) methods are time-consuming. Multiple overlapping-echo detachment (MOLED) imaging can achieve quantitative parametric mapping of a single slice within around one hundred milliseconds. Nevertheless, imaging the whole brain, which involves multiple slices, still takes a few seconds. To further accelerate qMRI, we introduce multiband SENSE (MB-SENSE) technology to MOLED to realize simultaneous multi-slice T2mapping.
Approach.The multiband MOLED (MB-MOLED) pulse sequence ...
Source: Physics in Medicine and Biology - September 19, 2023 Category: Physics Authors: Simin Li Taishan Kang Jian Wu Weikun Chen Qing Lin Zhigang Wu Jiazheng Wang Congbo Cai Shuhui Cai Source Type: research
Point-of-care AI-assisted stepwise ultrasound pneumothorax diagnosis
Phys Med Biol. 2023 Sep 19. doi: 10.1088/1361-6560/acfb70. Online ahead of print.ABSTRACTUltrasound is extensively utilized as a convenient and costeffective method in emergency situations. Unfortunately, the limited availability of skilled clinicians in emergency hinders the wider adoption of point-of-care ultrasound. To overcome this challenge, this paper aims to aid less experienced healthcare providers in emergency lung ultrasound scans.
Approach: To assist healthcare providers, it is important to have a comprehensive model that can automatically guide the entire process of lung ultrasound based on the clinicia...
Source: Physics in Medicine and Biology - September 19, 2023 Category: Physics Authors: Kyungsang Kim Fabiola Macruz Dufan Wu Christopher Bridge Suzannah McKinney Ahad Alhassan Al Saud Elshaimaa Sharaf Adam Pely Paul Danset Tom Duffy Davin Dhatt Varun Buch Andrew Liteplo Quanzheng Li Source Type: research
Tensor-conductance model for reducing the computational artifact in target tissue for low-frequency dosimetry
Phys Med Biol. 2023 Sep 18. doi: 10.1088/1361-6560/acfae0. Online ahead of print.ABSTRACTObjective
In protecting human from low-frequency (<100 kHz) exposure, an induced electric field strength is used as a physical quantity for assessment. However, the computational assessment suffers from a staircasing error because of the approximation of curved boundary discretized with cubic voxels. The international guidelines consider an additional reduction factor of 3 when setting the limit of external field strength computed from the permissible induced electric field. Here, a new method was proposed to reduce the stai...
Source: Physics in Medicine and Biology - September 18, 2023 Category: Physics Authors: Yinliang Diao Li Liu Nuo Deng Shilei Lyu Akimasa Hirata Source Type: research
Artificial intelligence in breast imaging: potentials and challenges
Phys Med Biol. 2023 Sep 18. doi: 10.1088/1361-6560/acfade. Online ahead of print.ABSTRACTBreast cancer, which is the most common type of malignant tumor among humans, is a leading cause of death in females. Standard treatment strategies, including neoadjuvant chemotherapy, surgery, postoperative chemotherapy, targeted therapy, endocrine therapy, and radiotherapy, are tailored for individual patients. Such personalized therapies have tremendously reduced the threat of breast cancer in females. Furthermore, early imaging screening plays an important role in reducing the treatment cycle and improving breast cancer prognosis. ...
Source: Physics in Medicine and Biology - September 18, 2023 Category: Physics Authors: Jiawei Li Danli Sheng Jiangang Chen Chao You Shuai Liu Huixiong Xu Cai Chang Source Type: research
Power-law spectrum-based objective function to train a generative adversarial network with transfer learning for the synthetic breast CT image
Phys Med Biol. 2023 Sep 18. doi: 10.1088/1361-6560/acfadf. Online ahead of print.ABSTRACTThis paper proposes a new objective function to improve the quality of synthesized breast CT images generated by the GAN and compares the GAN performances for transfer learning datasets from different image domains.
Approach: The proposed objective function, named beta loss function, is based on the fact that X-ray-based breast images follows the power-law spectrum. Accordingly, the exponent of the power-law spectrum (beta value) for breast CT images is approximately two. The beta loss function is defined in terms of L1distance...
Source: Physics in Medicine and Biology - September 18, 2023 Category: Physics Authors: Gihun Kim Jongduk Baek Source Type: research
