Texture preserving low dose CT image denoising using Pearson divergence
Phys Med Biol. 2024 Apr 30. doi: 10.1088/1361-6560/ad45a4. Online ahead of print.ABSTRACTThe mean squared error (MSE), also known as $L_2$ loss, has been widely used as a loss function to optimize image denoising models due to its strong performance as a mean estimator of the Gaussian noise model. Recently, various low-dose computed tomography (LDCT) image denoising methods using deep learning combined with the MSE loss have been developed; however, this approach has been observed to suffer from the regression-to-the-mean problem, leading to over-smoothed edges and degradation of texture in the image.
Approach: To ...
Source: Physics in Medicine and Biology - April 30, 2024 Category: Physics Authors: Jieun Oh Dufan Wu Boohwi Hong Dongheon Lee Minwoong Kang Quanzheng Li Kyungsang Kim Source Type: research
Corrigendum: Characterization of real-time cine MR imaging distortion on 0.35 T MRgRT with concentric cine imaging QA phantom (2024Phys. Med. Biol.69065009)
Phys Med Biol. 2024 Apr 26;69(10). doi: 10.1088/1361-6560/ad3dac.NO ABSTRACTPMID:38680052 | DOI:10.1088/1361-6560/ad3dac (Source: Physics in Medicine and Biology)
Source: Physics in Medicine and Biology - April 29, 2024 Category: Physics Authors: Shanti Marasini Mike Cole Austen Curcuru Lara M Dyke H Michael Gach Rocco Flores Taeho Kim Source Type: research
Active and passive dosimetry for beta-emitting radiopharmaceutical therapy agents in a custom SPECT/CT compatible phantom
We present a method for obtaining absorbed dose to water, measured with dosimeters, from beta-emitting radiopharmaceutical agents using a custom SPECT/CT compatible phantom for validation of Monte Carlo based absorbed dose to water estimates.
APPROACH: A cylindrical, acrylic SPECT/CT compatible phantom capable of housing an IBA EFD diode, IBA RAZOR diode, Exradin A20-375 parallel plate ion chamber, unlaminated EBT3 film, and thin TLD100 microcubes was constructed for the purpose of measuring absorbed dose to water from solutions of common beta-emitting radiopharmaceutical therapy agents. The phantom is equipped wit...
Source: Physics in Medicine and Biology - April 29, 2024 Category: Physics Authors: Andrew Bertinetti Timothy R Garcia Benjamin R Palmer Miesher Rodrigues Tyler James Bradshaw A Hans Vija Wesley S Culberson Source Type: research
A temporal enhanced semi-supervised training framework for needle segmentation in 3D ultrasound images
Phys Med Biol. 2024 Apr 29. doi: 10.1088/1361-6560/ad450b. Online ahead of print.ABSTRACTAutomated biopsy needle segmentation in 3D ultrasound images can be used for biopsy navigation, but it is quite challenging due to the low ultrasound image resolution and interference similar to the needle appearance. For 3D medical image segmentation, such deep learning (DL) networks as convolutional neural network (CNN) and transformer have been investigated. However, these segmentation methods require numerous labeled data for training, have difficulty in meeting the real-time segmentation requirement and involve high memory consump...
Source: Physics in Medicine and Biology - April 29, 2024 Category: Physics Authors: Mingwei Wen Pavel Shcherbakov Yang Xu Jing Li Yi Hu Quan Zhou Huageng Liang Li Yuan Xuming Zhang Source Type: research
Isocentric fixed angle irradiation-based DRR: a novel approach to enhance x-ray and CT image registration
Phys Med Biol. 2024 Apr 29. doi: 10.1088/1361-6560/ad450a. Online ahead of print.ABSTRACTDigitally Reconstructed Radiography (DRR) plays an important role in the registration of intraoperative X-ray and preoperative CT images. However, existing DRR algorithms often neglect the critical Isocentric Fixed Angle Irradiation (IFAI) principle in C-arm imaging, resulting in inaccurate simulation of X-ray images. This limitation degrades registration algorithms relying on DRR image libraries or employing DRR images (DRRs) to train neural network models. To address this issue, we propose a novel IFAI-based DRR method that accuratel...
Source: Physics in Medicine and Biology - April 29, 2024 Category: Physics Authors: Lixia Shu Meng Li Xi Guo Yu Chen Xin Pu Changyan Lin Source Type: research
Corrigendum: Characterization of real-time cine MR imaging distortion on 0.35 T MRgRT with concentric cine imaging QA phantom (2024Phys. Med. Biol.69065009)
Phys Med Biol. 2024 Apr 26;69(10). doi: 10.1088/1361-6560/ad3dac.NO ABSTRACTPMID:38680052 | DOI:10.1088/1361-6560/ad3dac (Source: Physics in Medicine and Biology)
Source: Physics in Medicine and Biology - April 29, 2024 Category: Physics Authors: Shanti Marasini Mike Cole Austen Curcuru Lara M Dyke H Michael Gach Rocco Flores Taeho Kim Source Type: research
Active and passive dosimetry for beta-emitting radiopharmaceutical therapy agents in a custom SPECT/CT compatible phantom
We present a method for obtaining absorbed dose to water, measured with dosimeters, from beta-emitting radiopharmaceutical agents using a custom SPECT/CT compatible phantom for validation of Monte Carlo based absorbed dose to water estimates.
APPROACH: A cylindrical, acrylic SPECT/CT compatible phantom capable of housing an IBA EFD diode, IBA RAZOR diode, Exradin A20-375 parallel plate ion chamber, unlaminated EBT3 film, and thin TLD100 microcubes was constructed for the purpose of measuring absorbed dose to water from solutions of common beta-emitting radiopharmaceutical therapy agents. The phantom is equipped wit...
Source: Physics in Medicine and Biology - April 29, 2024 Category: Physics Authors: Andrew Bertinetti Timothy R Garcia Benjamin R Palmer Miesher Rodrigues Tyler James Bradshaw A Hans Vija Wesley S Culberson Source Type: research
A temporal enhanced semi-supervised training framework for needle segmentation in 3D ultrasound images
Phys Med Biol. 2024 Apr 29. doi: 10.1088/1361-6560/ad450b. Online ahead of print.ABSTRACTAutomated biopsy needle segmentation in 3D ultrasound images can be used for biopsy navigation, but it is quite challenging due to the low ultrasound image resolution and interference similar to the needle appearance. For 3D medical image segmentation, such deep learning (DL) networks as convolutional neural network (CNN) and transformer have been investigated. However, these segmentation methods require numerous labeled data for training, have difficulty in meeting the real-time segmentation requirement and involve high memory consump...
Source: Physics in Medicine and Biology - April 29, 2024 Category: Physics Authors: Mingwei Wen Pavel Shcherbakov Yang Xu Jing Li Yi Hu Quan Zhou Huageng Liang Li Yuan Xuming Zhang Source Type: research
Isocentric fixed angle irradiation-based DRR: a novel approach to enhance x-ray and CT image registration
Phys Med Biol. 2024 Apr 29. doi: 10.1088/1361-6560/ad450a. Online ahead of print.ABSTRACTDigitally Reconstructed Radiography (DRR) plays an important role in the registration of intraoperative X-ray and preoperative CT images. However, existing DRR algorithms often neglect the critical Isocentric Fixed Angle Irradiation (IFAI) principle in C-arm imaging, resulting in inaccurate simulation of X-ray images. This limitation degrades registration algorithms relying on DRR image libraries or employing DRR images (DRRs) to train neural network models. To address this issue, we propose a novel IFAI-based DRR method that accuratel...
Source: Physics in Medicine and Biology - April 29, 2024 Category: Physics Authors: Lixia Shu Meng Li Xi Guo Yu Chen Xin Pu Changyan Lin Source Type: research
Dosimetric evaluation of different planning strategies for hypofractionated whole-breast irradiation technique
Conclusions: m-FSMP and r-FSMP can substantially enhance the homogeneity index (HI) and reduce V105, thereby minimizing the risk of acute skin toxicities, even though there may be a slight dose compromise for certain OARs.PMID:38670137 | DOI:10.1088/1361-6560/ad4445 (Source: Physics in Medicine and Biology)
Source: Physics in Medicine and Biology - April 26, 2024 Category: Physics Authors: Chunbo Tang Biaoshui Liu Jun Yuan Ji He Ruilian Xie Minfeng Huang Shanzhou Niu Hongdong Liu Source Type: research
Brain elastography in aging relates to fluid/solid trendlines
Phys Med Biol. 2024 Apr 26. doi: 10.1088/1361-6560/ad4446. Online ahead of print.ABSTRACTThe relatively new tools of brain elastography have established a general trendline for healthy, aging adult humans, whereby the brain's viscoelastic properties "soften" over many decades. Earlier studies of the aging brain have demonstrated a wide spectrum of changes in morphology and composition towards the later decades of lifespan. This leads to a major question of causal mechanisms: of the many changes documented in structure and composition of the aging brain, which ones drive the long term trendline for viscoelastic properties o...
Source: Physics in Medicine and Biology - April 26, 2024 Category: Physics Authors: Kevin J Parker Irteza Enan Kabir Marvin M Doyley Abrar Faiyaz Md Nasir Uddin Gilmer Flores Giovanni Schifitto Source Type: research
Contrast-enhanced photon-counting micro-CT of tumor xenograft models
Phys Med Biol. 2024 Apr 26. doi: 10.1088/1361-6560/ad4447. Online ahead of print.ABSTRACTPhoton-counting micro-computed tomography (micro-CT) is a major advance in small animal preclinical imaging. Small molecule- and nanoparticle-based contrast agents have been widely used to enable the differentiation of liver tumors from surrounding tissues using photon-counting micro-CT. However, there is a notable gap in the application of these market-available agents to the imaging of breast and ovarian tumors using photon-counting micro-CT. Herein, we have used photon-counting micro-CT to determine the effectiveness of these contra...
Source: Physics in Medicine and Biology - April 26, 2024 Category: Physics Authors: Mengzhou Li Xiaodong Guo Amit Verma Alena Rudkouskaya Antigone M McKenna Xavier Intes Ge Wang Margarida Barroso Source Type: research
Penalty weight tuning in high dose rate brachytherapy using multi-objective Bayesian optimization
Phys Med Biol. 2024 Apr 26. doi: 10.1088/1361-6560/ad4448. Online ahead of print.ABSTRACTTreatment plan optimization in high dose rate (HDR) brachytherapy often requires manual fine-tuning of penalty weights for each objective, which can be time-consuming and dependent on the planner's experience. To automate this process, this study used a multi-criteria approach called multi-objective Bayesian optimization with q-noisy expected hypervolume improvement as its acquisition function (MOBO-qNEHVI).

Approach: The treatment plans of 13 prostate cancer patients were retrospectively imported to a research treatme...
Source: Physics in Medicine and Biology - April 26, 2024 Category: Physics Authors: Hossein Jafarzadeh Majd Antaki Ximeng Mao Marie Duclos Farhad Maleki Shirin A Enger Source Type: research
Dosimetric evaluation of different planning strategies for hypofractionated whole-breast irradiation technique
Conclusions: m-FSMP and r-FSMP can substantially enhance the homogeneity index (HI) and reduce V105, thereby minimizing the risk of acute skin toxicities, even though there may be a slight dose compromise for certain OARs.PMID:38670137 | DOI:10.1088/1361-6560/ad4445 (Source: Physics in Medicine and Biology)
Source: Physics in Medicine and Biology - April 26, 2024 Category: Physics Authors: Chunbo Tang Biaoshui Liu Jun Yuan Ji He Ruilian Xie Minfeng Huang Shanzhou Niu Hongdong Liu Source Type: research
Brain elastography in aging relates to fluid/solid trendlines
Phys Med Biol. 2024 Apr 26. doi: 10.1088/1361-6560/ad4446. Online ahead of print.ABSTRACTThe relatively new tools of brain elastography have established a general trendline for healthy, aging adult humans, whereby the brain's viscoelastic properties "soften" over many decades. Earlier studies of the aging brain have demonstrated a wide spectrum of changes in morphology and composition towards the later decades of lifespan. This leads to a major question of causal mechanisms: of the many changes documented in structure and composition of the aging brain, which ones drive the long term trendline for viscoelastic properties o...
Source: Physics in Medicine and Biology - April 26, 2024 Category: Physics Authors: Kevin J Parker Irteza Enan Kabir Marvin M Doyley Abrar Faiyaz Md Nasir Uddin Gilmer Flores Giovanni Schifitto Source Type: research
