Homeobox B2 promotes malignant behavior and contributes to the radioresistance of nasopharyngeal carcinoma by regulating forkhead box protein O1
Conclusion: Our findings showed that HOXB2 acts as a tumor promoter in NPC, activating malignant behaviors and radioresistance of tumors via FOXO1 regulation. Moreover, the inactivation of HOXB2 or activation of FOXO1 are potential strategies to inhibit tumor progression and overcome radioresistance in NPC.PMID:38617001 | PMC:PMC11008478 | DOI:10.7150/ijms.93128 (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - April 15, 2024 Category: Biomedical Science Authors: Jinhai Chen Min Mao Zhaoen Ma Jie Liu Minqiong Jiang Guangui Chen Yali Xu Source Type: research

Head and neck cancer in times of COVID-19: Emotion-based medicine
Acta Otorrinolaringol Esp. 2021 Jan-Feb;72(1):1-2. doi: 10.1016/j.otorri.2020.08.001. Epub 2020 Oct 1.NO ABSTRACTPMID:38620342 | PMC:PMC7528842 | DOI:10.1016/j.otorri.2020.08.001 (Source: Acta Otorrinolaringologica Espanola)
Source: Acta Otorrinolaringologica Espanola - April 15, 2024 Category: ENT & OMF Authors: J Alexander Sistiaga Su árez Fernando L ópez Álvarez Eduardo Ferrandis Perep érez Pablo Parente Arias Pedro D íaz de Cerio Canduela en representaci ón de la Comisión de Cabeza y Cuello y Base de Cráneo de la SEORL-CCC Source Type: research

Homeobox B2 promotes malignant behavior and contributes to the radioresistance of nasopharyngeal carcinoma by regulating forkhead box protein O1
Conclusion: Our findings showed that HOXB2 acts as a tumor promoter in NPC, activating malignant behaviors and radioresistance of tumors via FOXO1 regulation. Moreover, the inactivation of HOXB2 or activation of FOXO1 are potential strategies to inhibit tumor progression and overcome radioresistance in NPC.PMID:38617001 | PMC:PMC11008478 | DOI:10.7150/ijms.93128 (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - April 15, 2024 Category: Biomedical Science Authors: Jinhai Chen Min Mao Zhaoen Ma Jie Liu Minqiong Jiang Guangui Chen Yali Xu Source Type: research

Head and neck cancer in times of COVID-19: Emotion-based medicine
Acta Otorrinolaringol Esp. 2021 Jan-Feb;72(1):1-2. doi: 10.1016/j.otorri.2020.08.001. Epub 2020 Oct 1.NO ABSTRACTPMID:38620342 | PMC:PMC7528842 | DOI:10.1016/j.otorri.2020.08.001 (Source: Acta Otorrinolaringologica Espanola)
Source: Acta Otorrinolaringologica Espanola - April 15, 2024 Category: ENT & OMF Authors: J Alexander Sistiaga Su árez Fernando L ópez Álvarez Eduardo Ferrandis Perep érez Pablo Parente Arias Pedro D íaz de Cerio Canduela en representaci ón de la Comisión de Cabeza y Cuello y Base de Cráneo de la SEORL-CCC Source Type: research

Homeobox B2 promotes malignant behavior and contributes to the radioresistance of nasopharyngeal carcinoma by regulating forkhead box protein O1
Conclusion: Our findings showed that HOXB2 acts as a tumor promoter in NPC, activating malignant behaviors and radioresistance of tumors via FOXO1 regulation. Moreover, the inactivation of HOXB2 or activation of FOXO1 are potential strategies to inhibit tumor progression and overcome radioresistance in NPC.PMID:38617001 | PMC:PMC11008478 | DOI:10.7150/ijms.93128 (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - April 15, 2024 Category: Biomedical Science Authors: Jinhai Chen Min Mao Zhaoen Ma Jie Liu Minqiong Jiang Guangui Chen Yali Xu Source Type: research

Head and neck cancer in times of COVID-19: Emotion-based medicine
Acta Otorrinolaringol Esp. 2021 Jan-Feb;72(1):1-2. doi: 10.1016/j.otorri.2020.08.001. Epub 2020 Oct 1.NO ABSTRACTPMID:38620342 | PMC:PMC7528842 | DOI:10.1016/j.otorri.2020.08.001 (Source: Acta Otorrinolaringologica Espanola)
Source: Acta Otorrinolaringologica Espanola - April 15, 2024 Category: ENT & OMF Authors: J Alexander Sistiaga Su árez Fernando L ópez Álvarez Eduardo Ferrandis Perep érez Pablo Parente Arias Pedro D íaz de Cerio Canduela en representaci ón de la Comisión de Cabeza y Cuello y Base de Cráneo de la SEORL-CCC Source Type: research

Homeobox B2 promotes malignant behavior and contributes to the radioresistance of nasopharyngeal carcinoma by regulating forkhead box protein O1
Conclusion: Our findings showed that HOXB2 acts as a tumor promoter in NPC, activating malignant behaviors and radioresistance of tumors via FOXO1 regulation. Moreover, the inactivation of HOXB2 or activation of FOXO1 are potential strategies to inhibit tumor progression and overcome radioresistance in NPC.PMID:38617001 | PMC:PMC11008478 | DOI:10.7150/ijms.93128 (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - April 15, 2024 Category: Biomedical Science Authors: Jinhai Chen Min Mao Zhaoen Ma Jie Liu Minqiong Jiang Guangui Chen Yali Xu Source Type: research

Head and neck cancer in times of COVID-19: Emotion-based medicine
Acta Otorrinolaringol Esp. 2021 Jan-Feb;72(1):1-2. doi: 10.1016/j.otorri.2020.08.001. Epub 2020 Oct 1.NO ABSTRACTPMID:38620342 | PMC:PMC7528842 | DOI:10.1016/j.otorri.2020.08.001 (Source: Acta Otorrinolaringologica Espanola)
Source: Acta Otorrinolaringologica Espanola - April 15, 2024 Category: ENT & OMF Authors: J Alexander Sistiaga Su árez Fernando L ópez Álvarez Eduardo Ferrandis Perep érez Pablo Parente Arias Pedro D íaz de Cerio Canduela en representaci ón de la Comisión de Cabeza y Cuello y Base de Cráneo de la SEORL-CCC Source Type: research

Homeobox B2 promotes malignant behavior and contributes to the radioresistance of nasopharyngeal carcinoma by regulating forkhead box protein O1
Conclusion: Our findings showed that HOXB2 acts as a tumor promoter in NPC, activating malignant behaviors and radioresistance of tumors via FOXO1 regulation. Moreover, the inactivation of HOXB2 or activation of FOXO1 are potential strategies to inhibit tumor progression and overcome radioresistance in NPC.PMID:38617001 | PMC:PMC11008478 | DOI:10.7150/ijms.93128 (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - April 15, 2024 Category: Biomedical Science Authors: Jinhai Chen Min Mao Zhaoen Ma Jie Liu Minqiong Jiang Guangui Chen Yali Xu Source Type: research

Head and neck cancer in times of COVID-19: Emotion-based medicine
Acta Otorrinolaringol Esp. 2021 Jan-Feb;72(1):1-2. doi: 10.1016/j.otorri.2020.08.001. Epub 2020 Oct 1.NO ABSTRACTPMID:38620342 | PMC:PMC7528842 | DOI:10.1016/j.otorri.2020.08.001 (Source: Acta Otorrinolaringologica Espanola)
Source: Acta Otorrinolaringologica Espanola - April 15, 2024 Category: ENT & OMF Authors: J Alexander Sistiaga Su árez Fernando L ópez Álvarez Eduardo Ferrandis Perep érez Pablo Parente Arias Pedro D íaz de Cerio Canduela en representaci ón de la Comisión de Cabeza y Cuello y Base de Cráneo de la SEORL-CCC Source Type: research

Homeobox B2 promotes malignant behavior and contributes to the radioresistance of nasopharyngeal carcinoma by regulating forkhead box protein O1
Conclusion: Our findings showed that HOXB2 acts as a tumor promoter in NPC, activating malignant behaviors and radioresistance of tumors via FOXO1 regulation. Moreover, the inactivation of HOXB2 or activation of FOXO1 are potential strategies to inhibit tumor progression and overcome radioresistance in NPC.PMID:38617001 | PMC:PMC11008478 | DOI:10.7150/ijms.93128 (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - April 15, 2024 Category: Biomedical Science Authors: Jinhai Chen Min Mao Zhaoen Ma Jie Liu Minqiong Jiang Guangui Chen Yali Xu Source Type: research

Head and neck cancer in times of COVID-19: Emotion-based medicine
Acta Otorrinolaringol Esp. 2021 Jan-Feb;72(1):1-2. doi: 10.1016/j.otorri.2020.08.001. Epub 2020 Oct 1.NO ABSTRACTPMID:38620342 | PMC:PMC7528842 | DOI:10.1016/j.otorri.2020.08.001 (Source: Acta Otorrinolaringologica Espanola)
Source: Acta Otorrinolaringologica Espanola - April 15, 2024 Category: ENT & OMF Authors: J Alexander Sistiaga Su árez Fernando L ópez Álvarez Eduardo Ferrandis Perep érez Pablo Parente Arias Pedro D íaz de Cerio Canduela en representaci ón de la Comisión de Cabeza y Cuello y Base de Cráneo de la SEORL-CCC Source Type: research

Impact of outside referral and dental extractions on package time with post ‐operative radiation therapy for head and neck cancer
ConclusionsWe identified that outside referrals, but not dental extractions, prolong treatment package times. We also saw no effect of package time on RFS or OS. These results suggest that patients requesting outside facility referrals for RT may benefit from a streamlined program that expedites the referral process. (Source: Journal of Medical Imaging and Radiation Oncology)
Source: Journal of Medical Imaging and Radiation Oncology - April 15, 2024 Category: Radiology Authors: Joseph Nguyen, Christopher McLaughlin Tags: Radiation Oncology —Original Article Source Type: research

Estimating the Prognostic Value of the NTRK Fusion Biomarker for Comparative Effectiveness Research in The Netherlands
ConclusionsNTRK+ patients may have an increased risk of death compared withNTRK − patients. When using historic control data to assess the comparative effectiveness of TRK inhibitors, the prognostic value of theNTRK fusion biomarker should therefore be accounted for. (Source: Molecular Diagnosis and Therapy)
Source: Molecular Diagnosis and Therapy - April 14, 2024 Category: Molecular Biology Source Type: research

Association of Insomnia and Obstructive Sleep Apnea with Worse Oral Mucositis and Quality of Life in Head and Neck Cancer Patients Undergoing Radiation Therapy
CONCLUSION: Insomnia and OSA are highly prevalent in patients with HNC undergoing RT. These sleep disturbances are associated with worse QOL and OM during treatment.PMID:38611012 | DOI:10.3390/cancers16071335 (Source: Cancer Control)
Source: Cancer Control - April 13, 2024 Category: Cancer & Oncology Authors: Austin J Iovoli Kelsey Smith Han Yu Melissa A Kluczynski Carla R Jungquist Andrew D Ray Mark K Farrugia Fangyi Gu Anurag K Singh Source Type: research