Correction to: Clinical usefulness of eribulin as first- or second-line chemotherapy for recurrent HER2-negative breast cancer: a randomized phase II study (JBCRG-19)
(Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - September 27, 2022 Category: Cancer & Oncology Source Type: research

Functional outcomes at PICU discharge in hemato-oncology children at a tertiary oncology center in Hong Kong
ConclusionCritically ill children with hemato-oncological diseases had a higher rate of developing new morbidities (18.8%) compared with the general PICU population (4 –8%). This was associated with severity of illness at admission. Further work is warranted to understand the lasting effects of these new morbidities and mitigating interventions. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - September 23, 2022 Category: Cancer & Oncology Source Type: research

Human papillomavirus testing and cytology using physician-collected uterine cervical samples vs. self-collected vaginal samples and urine samples
ConclusionsThe obtained results were consistent between physician- and self-collected samples as well as between physician-collected and urine samples. Considering that the agreement rate was particularly high for the high-risk HPV types 16 and 18, HPV testing using physician-collected samples, self-collected samples, and urine samples was equally effective for the types with high carcinogenicity. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - September 11, 2022 Category: Cancer & Oncology Source Type: research

Predictive role of circulatory levels of high-mobility group box 1 for radiation pneumonitis in patients with non-small cell lung cancer treated with definitive thoracic radiotherapy
ConclusionsHigher serum HMGB1 levels were significantly associated with the risk of grade  ≥ 3 radiation pneumonitis in patients with lung cancer, and therefore, HMGB1 could be a potential blood biomarker for predicting severe radiation pneumonitis. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - September 3, 2022 Category: Cancer & Oncology Source Type: research

The ‘best friend effect’: a promising tool to encourage HPV vaccination in Japan
ConclusionIf mothers who have had their daughters vaccinated were to recommend HPV vaccination to their close friends, ‘the best friend effect’ should promote others to be vaccinated. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - September 3, 2022 Category: Cancer & Oncology Source Type: research

Usefulness of ultrasonography and elastography in diagnosing oxaliplatin-induced sinusoidal obstruction syndrome
ConclusionsThe usefulness of HokUS-10 score was not demonstrated; however, some HokUS-10 parameters and SWE could be useful for the early diagnosis of oxaliplatin-induced SOS. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - August 30, 2022 Category: Cancer & Oncology Source Type: research

Brigatinib in Japanese patients with tyrosine kinase inhibitor-naive ALK-positive non-small cell lung cancer: first results from the phase 2  J-ALTA study
ConclusionsIn the J-ALTA TKI-naive cohort, brigatinib demonstrated clinically meaningful efficacy consistent with the international phase 3 study. The safety profile in Japanese patients was consistent with previous studies. Brigatinib is an important first-line option for Japanese patients withALK-positive NSCLC.Clinical registrationNCT03410108 (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - August 29, 2022 Category: Cancer & Oncology Source Type: research

First-line pembrolizumab for patients with early relapsing urothelial carcinoma after perioperative chemotherapy: a retrospective analysis of bladder cancer and upper urinary tract cancer
ConclusionsFirst-line pembrolizumab in earlier clinical settings for highly malignant tumors might improve the prognosis of patients with early relapsing disease after the receipt of platinum-based perioperative chemotherapy. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - August 27, 2022 Category: Cancer & Oncology Source Type: research

Long-term outcomes of D2 vs. D3 lymph node dissection for cT2N0M0 colorectal cancer: a multi ‑institutional retrospective analysis
ConclusionThe long-term outcomes did not differ between the D2 and D3 groups and the extent of LND was not associated with prognosis for cT2N0M0 CRC. Therefore, D2 LND may be sufficient for cT2N0N0 CRC treatment. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - August 27, 2022 Category: Cancer & Oncology Source Type: research

Real-world clinical outcomes in Japanese patients with locally advanced squamous cell carcinoma of the  head and neck treated with radiotherapy plus cetuximab: a prospective observational study (JROSG12-2)
ConclusionAs a result of the large number of elderly patients in clinical practice,  toxicity reduced TCR. BRT-induced pneumonitis, which is sometimes fatal, was found to be more frequent than with chemotherapy plus cetuximab. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - August 24, 2022 Category: Cancer & Oncology Source Type: research

Clinical outcomes of brain metastasectomy from soft tissue and bone sarcomas: a systematic review
The objective of this systematic review was to evaluate survival outcomes post-brain metastasectomy for patients with soft tissue and bone sarcomas.MethodsA systematic review was conducted examining survival outcomes among adults and children with soft tissue and bone sarcoma undergoing brain metastasectomy, in the English language from inception up to May 31, 2021. Two reviewers independently evaluated and screened the literature, extracted the data, and graded the included studies. The body of evidence was evaluated and graded according to the Newcastle –Ottawa Quality Assessment Scale for Cohort Studies and the Joanna...
Source: International Journal of Clinical Oncology - August 22, 2022 Category: Cancer & Oncology Source Type: research

miR-339-3p inhibits cell growth and epithelial –mesenchymal transition in nasopharyngeal carcinoma by modulating the KAT6A/TRIM24 axis
ConclusionConclusively, miR-339-3p inhibited the growth and EMT of NPC cells via the KAT6A/TRIM24 axis. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - August 17, 2022 Category: Cancer & Oncology Source Type: research

Clinical effectiveness of surgical treatment after lenvatinib administration for hepatocellular carcinoma
ConclusionsSurgical treatment after lenvatinib administration may be a useful therapeutic option for select patients with hepatocellular carcinoma. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - August 12, 2022 Category: Cancer & Oncology Source Type: research

Letter to the Editor: Inflammation influences the prognosis of hepatocellular carcinoma
(Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - August 12, 2022 Category: Cancer & Oncology Source Type: research

The utility of serum osteopontin levels for predicting postoperative complications after colorectal cancer surgery
ConclusionIncreased postoperative OPN was associated with increased postoperative inflammatory host responses and POC after CRC surgery. Serum OPN level may be a useful biomarker for early prediction of POC and it may provide additional information for treatment decisions to prevent POC. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - August 11, 2022 Category: Cancer & Oncology Source Type: research