International Journal of Clinical Oncology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Association between financial toxicity and health-related quality of life of patients with gynecologic cancer
ConclusionsGreater financial toxicity was associated with worse health-related quality of life scores, such as financial difficulty in gynecologic cancer patients and body image in cervical cancer patients as strong associations, and weakly associated with general health-related quality of life scores and several function/symptom scales. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - January 17, 2023 Category: Cancer & Oncology Source Type: research

Correction to: Brigatinib in Japanese patients with tyrosine kinase inhibitor-naive ALK-positive non-small cell lung cancer: first results from the phase 2  J-ALTA study
(Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - January 17, 2023 Category: Cancer & Oncology Source Type: research

Long-term results of chemoradiotherapy with elective nodal irradiation for resectable locally advanced esophageal cancer in three-dimensional planning system
ConclusionThe long-term results of definitive CRT with ENI for resectable LA-ESCC were favorable. ENI with a 3D planning system may reduce regional LN recurrence and late adverse events. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - January 16, 2023 Category: Cancer & Oncology Source Type: research

Association of chemotherapy and comorbidities with overall survival in elderly patients with early breast cancer: a French population-based propensity score-matched analysis
ConclusionAdditional chemotherapy in elderly with early breast cancer is feasible and associated with overall survival benefit, supporting the importance of chemotherapy considerations in this population, and of avoiding undertreatment based on chronological age considerations alone. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - January 16, 2023 Category: Cancer & Oncology Source Type: research

The impact of the advanced lung cancer inflammation index on the outcomes of patients with metastatic colorectal cancer who receive chemotherapy
ConclusionALI comprehensively evaluates the prognostic host status and is a reliable prognosticator for the mCRC patients with chemotherapy. Calculating pretreatment ALI may serve as a cost-effective and easily available tool for constructing treatment strategies. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - January 13, 2023 Category: Cancer & Oncology Source Type: research

Long-term results of a phase 2 study of neoadjuvant chemotherapy with molecularly targeted agents for locally advanced rectal cancer
ConclusionsThe use of molecularly targeted agents in the neoadjuvant setting for locally advanced rectal cancer has an acceptable prognosis. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - January 9, 2023 Category: Cancer & Oncology Source Type: research

Efficacy and safety of nivolumab with ipilimumab for recurrent malignant pleural mesothelioma after primary surgical intervention
ConclusionNivolumab with ipilimumab treatment in patients with recurrent MPM after primary surgical treatment may be clinically efficacious, although serious AEs may be frequently observed. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - January 7, 2023 Category: Cancer & Oncology Source Type: research

Reciprocal expression of the immune response genes CXCR3 and IFI44L as module hubs are associated with patient survivals in primary central nervous system lymphoma
ConclusionThese results indicate that the differential expression and balance of immune response and microenvironment genes may be required for PCNSL tumor growth or prognosis prediction, which would help understanding the mechanism of tumorigenesis and potential therapeutic targets in PCNSL. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - January 6, 2023 Category: Cancer & Oncology Source Type: research

Real-world practice of estrogen therapy after surgery for endometrial cancer: a descriptive study using a Japanese claims database
ConclusionThe present study shows that ET after endometrial cancer surgery may be underused, even in women who underwent surgery between 40 and 44  years of age and without adjuvant therapy. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - January 4, 2023 Category: Cancer & Oncology Source Type: research

Final efficacy and safety results and biomarker analysis of a phase 2 study of cabozantinib in Japanese patients with advanced renal cell carcinoma
ConclusionsUpdated analyses demonstrate the long-term efficacy and safety of cabozantinib in Japanese patients with advanced RCC after at least one VEGFR-TKI therapy. Responders tended to show lower baseline HGF levels ClinicalTrials.gov Identifier: NCT03339219. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - January 3, 2023 Category: Cancer & Oncology Source Type: research

Joint-preservation surgery for bone sarcoma in adolescents and young adults
AbstractBone sarcoma often occurs in childhood, as well as in adolescents and young adults (AYAs). AYAs differ from pediatric patients in that their bone is skeletally mature and the physis has almost disappeared with the completion of growth. Although AYAs spend less time outside, they often participate in sports activities, as well as driving, working, and raising a family, which are natural activities in daily living. Multidisciplinary approaches involving imaging, multi-agent chemotherapy, surgical procedures, and careful postoperative care has facilitated an increase in limb-sparing surgery for bone sarcoma. In additi...
Source: International Journal of Clinical Oncology - January 1, 2023 Category: Cancer & Oncology Source Type: research

Current methods of preventing infectious disease and managing febrile neutropenia in childhood cancer patients: a nationwide survey in Japan
ConclusionAs a whole, intensive care for infectious prophylaxis or FN is applied in Japan; however, the methods vary among centers, and some are excessive or inadequate. Therefore, it is desirable to conduct clinical trials and establish adequate care protocols for infection in children with cancer in Japan. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - December 31, 2022 Category: Cancer & Oncology Source Type: research

Predictive factors of collateral vessel development induced by oxaliplatin-based chemotherapy
ConclusionA  ≥ 1.76 increase in the FIB-4 index and a ≥ 30% increase in spleen size after 6 months of oxaliplatin-based chemotherapy were significant predictive markers for collateral vessel development. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - December 31, 2022 Category: Cancer & Oncology Source Type: research

Which modality is better to diagnose high-grade transformation in retroperitoneal liposarcoma? Comparison of computed tomography, positron emission tomography, and magnetic resonance imaging
ConclusionsContrast-enhanced CT and PET were useful for predicting DDLS and FNCLCC grade 2/3, while MRI was inferior to these two modalities. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - December 30, 2022 Category: Cancer & Oncology Source Type: research

The presence of lymph node metastases and time to castration resistance predict the therapeutic effect of enzalutamide for castration-resistant prostate cancer
ConclusionsTime to CRPC and lymph node metastasis were predictors of the PSA response rate and PSA –PFS. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - December 29, 2022 Category: Cancer & Oncology Source Type: research