International Journal of Clinical Oncology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Announcement: Third Joint Committee Report on Diabetes and Cancer
(Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - February 10, 2024 Category: Cancer & Oncology Source Type: research

Prognostic impact of peripheral blood WT1 mRNA dynamics in patients with acute myeloid leukemia treated with venetoclax combination therapy
ConclusionThis study demonstrates thatWT1 mRNA dynamics can be a useful marker for assessing long-term prognosis of VEN combination therapy for AML. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - February 9, 2024 Category: Cancer & Oncology Source Type: research

EGFR mutation impacts recurrence in high-risk early-stage lung adenocarcinoma in the IASLC grading system
ConclusionsThis study provides evidence that patients withEGFRm-positive stage I lung adenocarcinoma in the high-risk group have an increased risk of recurrence, including CNS metastasis. These findings highlight the need for development of adjuvant treatment in this population. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - February 6, 2024 Category: Cancer & Oncology Source Type: research

Skeletal muscle status and survival among patients with advanced biliary tract cancer
ConclusionsSkeletal muscle quantity and quality and their serial changes were associated with survival outcomes in patients with advanced biliary tract cancer. Our data highlight the importance of designing nutritional and physical interventions for improvements in skeletal muscle status. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - February 6, 2024 Category: Cancer & Oncology Source Type: research

Hydronephrosis severity as a predictor of postoperative renal function decline following laparoscopic radical nephroureterectomy
ConclusionModerate or severe hydronephrosis is associated with a modest postoperative decline in renal function, while mild hydronephrosis is not. Our predictive model may be useful in predicting postoperative renal function insufficiency and guiding decision-making for perioperative medical treatment. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - February 6, 2024 Category: Cancer & Oncology Source Type: research

The efficacy of palbociclib and ribociclib in the first-line treatment of metastatic hormone receptor-positive, human epidermal growth factor receptor 2-negative breast cancer in male patients: a Turkish oncology group (TOG) study
This study is a multicenter, retrospective study. We included male patients with HR  + and HER2-metastatic breast cancer who received palbociclib or ribociclib as first-line treatment. Our primary endpoints were progression-free survival (PFS), overall response rates (ORR), and drug-related adverse effects.ResultsA total of 46 male patients from 27 institutions were enrolled. The median age at initiation of CDK 4/6 inhibitors was 63.64  ± 13.69 years, with a median follow-up of 21.33 (95% CI 14.92–27.74) months. The ORR were 84% for palbociclib and 76.2% for ribociclib. The mPFS for the entire cohort was 28.06Â...
Source: International Journal of Clinical Oncology - February 4, 2024 Category: Cancer & Oncology Source Type: research

Low skeletal muscle radiodensity is a risk factor for adjuvant chemotherapy discontinuation in colorectal cancer
ConclusionThe low SMR group showed higher treatment incompletion rates and received lower drug doses during adjuvant chemotherapy. Low SMR independently contributed to treatment non-completion in colorectal cancer patients. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - January 29, 2024 Category: Cancer & Oncology Source Type: research

Adjuvant and neo-adjuvant therapy for non-small cell lung cancer without EGFR mutations or ALK rearrangements
AbstractSurgical resection is the most effective therapeutic option for the cure in early stage resectable non-small-cell lung cancer (NSCLC). However, despite complete resection, up to 70% of patients die within 5 years mainly due to tumor recurrence in extra-thoracic organs. Adjuvant or neoadjuvant platinum-based chemotherapy may improve postoperative survival, but the absolute survival benefit is modest with an around 5% improvement at 5 years. Recent advance in systemic therapy has changed treatment strategy for advanced unresectable NSCLC, and also has provided a paradigm shift in treatment strategy for resectable NSC...
Source: International Journal of Clinical Oncology - January 28, 2024 Category: Cancer & Oncology Source Type: research

Impact of sarcopenia on recurrent biliary obstruction after EUS-guided biliary drainage in patients with malignant biliary obstruction
ConclusionSarcopenia is an independent indicator of RBO in patients with MBO who receive EUS-BD with SEMS. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - January 27, 2024 Category: Cancer & Oncology Source Type: research

The prognostic impact of treatment centralization in patients with testicular germ cell tumors: analysis of hospital-based cancer registry data in Japan
ConclusionOur results indicate that stage II and III TGCT patients experience lower survival rates at low-volume institutions and would benefit from treatment centralization. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - January 24, 2024 Category: Cancer & Oncology Source Type: research

Effects of postoperative oral elemental nutritional supplement on skeletal muscle loss after gastrectomy for gastric cancer
ConclusionED administration for 6 –8 weeks following gastrectomy had no inhibitory effect on skeletal muscle loss at 1 year postoperatively.Clinical Trial RegistrationUMIN000023455. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - January 16, 2024 Category: Cancer & Oncology Source Type: research

Phase II study of S-1 plus docetaxel as first-line treatment for older patients with advanced gastric cancer (OGSG 0902)
ConclusionsThese findings indicate that S-1 plus docetaxel as first-line treatment for older patients is feasible and that it has promising efficacy against advanced gastric cancer. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - January 16, 2024 Category: Cancer & Oncology Source Type: research

Predictors for early recurrence beyond up-to-7 or distant metastasis after hepatocellular carcinoma resection: proposal for borderline resectable HCC
ConclusionsIn this retrospective analysis, MVI, TBS, and ALBI could predict severe early recurrence after hepatic resection for HCC, and patients with these risk factors had a poor prognosis. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - January 16, 2024 Category: Cancer & Oncology Source Type: research

Analgesic efficacy and safety of percutaneous thermal ablation plus cementoplasty for painful bone metastases: a systematic review and meta-analysis
ConclusionsThe updated systematic review and meta-analysis indicates that PTA  + PCP for painful bone metastases is safe, and can lead to rapid and sustained pain reduction. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - January 13, 2024 Category: Cancer & Oncology Source Type: research

Impact of prostate position-based image-guidance in intensity-modulated radiation therapy for localized prostate cancer
ConclusionsThe use of P-IGRT with higher doses and smaller margins was correlated with significantly better biochemical control, and a lower incidence of rectal bleeding in IMRT for intermediate-risk prostate cancer. The enhanced accuracy using P-IGRT has the potential to independently improve disease control and reduce late rectal bleeding. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - January 8, 2024 Category: Cancer & Oncology Source Type: research