Seroprevalence of Anaplasma phagocytophilum, Ehrlichia spp. and Borrelia burgdorferi infections in horses: first report from Northern Bulgaria - Short communication.
Abstract
Lyme borreliosis, granulocytic anaplasmosis and monocytic ehrlichiosis are well studied in humans and dogs. In horses, these diseases are not widely investigated and limited information is available about their occurrence. The purpose of this study was to present the first ELISA-based report on the seroprevalence of Anaplasma phagocytophilum, Ehrlichia spp. and Borrelia burgdorferi in horses from Northern Bulgaria. A total of 192 horses were investigated from three regions in Northern Bulgaria (Northwestern, North-Central and Northeastern Bulgaria). All equine sera were tested for A. phagocytophil...
Source: Acta Veterinaria Hungarica - May 31, 2019 Category: Veterinary Research Authors: Tsachev I, Baymakova M, Pantchev N Tags: Acta Vet Hung Source Type: research
Canine vector-borne disease: mapping and the accuracy of forecasting using big data from the veterinary community.
Abstract
Diagnosis, treatment, and prevention of vector-borne disease (VBD) in pets is one cornerstone of companion animal practices. Veterinarians are facing new challenges associated with the emergence, reemergence, and rising incidence of VBD, including heartworm disease, Lyme disease, anaplasmosis, and ehrlichiosis. Increases in the observed prevalence of these diseases have been attributed to a multitude of factors, including diagnostic tests with improved sensitivity, expanded annual testing practices, climatologic and ecological changes enhancing vector survival and expansion, emergence or recogniti...
Source: Animal Health Research Reviews - May 31, 2019 Category: Veterinary Research Authors: Self SCW, Liu Y, Nordone SK, Yabsley MJ, Walden HS, Lund RB, Bowman DD, Carpenter C, McMahan CS, Gettings JR Tags: Anim Health Res Rev Source Type: research
Acute acalculous cholecystitis as a manifestation of ehrlichiosis
Publication date: Available online 22 May 2019Source: Ticks and Tick-borne DiseasesAuthor(s): Rahul Mahapatra, Luis A. Marcos, David Cohen, Asa W. Viccellio, Aaron Sasson, Jela Bandovic, Eric D. Spitzer, Audun Lier (Source: Ticks and Tick borne Diseases)
Source: Ticks and Tick borne Diseases - May 24, 2019 Category: Zoology Source Type: research
Emerging Roles of Autophagy and Inflammasome in Ehrlichiosis
Human monocytic ehrlichiosis (HME) is a potentially life-threatening tick-borne rickettsial disease (TBRD) caused by the obligate intracellular Gram-negative bacteria, Ehrlichia. Fatal HME is presented with acute ailments of sepsis and toxic shock-like symptoms that can eventually evolve to multi-organ failure and death. Early clinical and laboratory diagnosis of HME are problematic due to non-specific flu-like symptoms and limitations in the current diagnostic testing. Several studies in murine models showed that cell-mediated immunity acts as a "double-edged sword" in fatal ehrlichiosis. Protective components are mainly ...
Source: Frontiers in Immunology - May 7, 2019 Category: Allergy & Immunology Source Type: research
Vector-borne Diseases: An Ongoing Threat
Vector-borne diseases (VBDs) are responsible for significant morbidity and mortality worldwide. In the United States, VBDs continue to increase, with 9 new VBDs identified since 2004 and most recently in 2017 a new vector, Haemaphysalis longicornis. Vectors such as ticks, mosquitoes, and fleas are capable of transmitting bacteria, viruses, and parasites. This updated review of the current recommendations for the diagnosis and treatment of Lyme disease, Rocky Mountain spotted fever, ehrlichiosis, and West Nile virus will help prepare nurse practitioners to provide safe, competent care for their patients and communities at l...
Source: The Journal for Nurse Practitioners - April 5, 2019 Category: Nursing Authors: Karen S. Moore Tags: Feature Article Source Type: research
Lyme Neuroborreliosis - The Mystifying Pitfall: "Neuropathology and Current Therapeutics".
Authors: Chavda V, Patel S
Abstract
Lyme's Disease (LD) is a severe rapidly growing broad spectrum chronic infection caused by the bacterium 'Borrelia (B.) burgdoferi', which can be easily transmitted through the bite of certain species of ticks. The prevalence of LD is swiftly mounting in present scenario in many countries from species to species. Although Lyme's infection is now detectable via serologic examination of early and late Lyme neuroborreliosis (LNB), the management of persistent symptoms is still fraught with quora of doubt and debate. LD is a multisystem spirochete which results after the dis...
Source: Recent Patents on Anti-Infective Drug Discovery - March 29, 2019 Category: Infectious Diseases Tags: Recent Pat Antiinfect Drug Discov Source Type: research
Human ehrlichiosis at a tertiary-care academic medical center: Clinical associations and outcomes of transplant patients and patients with hemophagocytic lymphohistiocytosis
ConclusionsEhrlichia-induced HLH is a potential serious complication with relatively high occurrence rate; patients manifest severe disease with end-organ damage requiring longer hospital stay. (Source: Blood Cells, Molecules, and Diseases)
Source: Blood Cells, Molecules, and Diseases - March 20, 2019 Category: Hematology Source Type: research
Human ehrlichiosis at a tertiary-care academic medical center: Clinical associations and outcomes of transplant patients and patients with hemophagocytic lymphohistiocytosis.
CONCLUSIONS: Ehrlichia-induced HLH is a potential serious complication with relatively high occurrence rate; patients manifest severe disease with end-organ damage requiring longer hospital stay.
PMID: 30913447 [PubMed - as supplied by publisher] (Source: Blood Cells, Molecules and Diseases)
Source: Blood Cells, Molecules and Diseases - March 18, 2019 Category: Hematology Authors: Otrock ZK, Eby CS, Burnham CD Tags: Blood Cells Mol Dis Source Type: research
The rash with maculopapules and fever in adults
We describe various conditions that result in a fever and maculopapular rash in adults. These include infectious processes (meningococcemia, infectious mononucleosis, West Nile virus, zika virus, rubella, primary human immunodeficiency virus, parvovirus B19, ebolavirus), tick-borne illnesses (Rocky Mountain spotted fever, ehrlichiosis), and hypersensitivity reactions (exanthematous drug reactions). (Source: Clinics in Dermatology)
Source: Clinics in Dermatology - February 28, 2019 Category: Dermatology Authors: Sonal Muzumdar, Marti Jill Rothe, Jane M. Grant-Kels Source Type: research
Genetic diversity of Ehrlichia canis in dogs from Turkey inferred by TRP36 sequence analysis and phylogeny
Publication date: Available online 10 February 2019Source: Comparative Immunology, Microbiology and Infectious DiseasesAuthor(s): Munir Aktas, Sezayi ÖzübekAbstractCanine monocytic ehrlichiosis, an important tick-borne disease caused by Ehrlichia canis, is cosmopolitan but particularly prevalent in tropical and subtropical regions. In Turkey, the genetic diversity of E. canis remains undefined. The aim of this study was to characterize E. canis in naturally infected dogs from Turkey by sequencing and phylogenetic analysis of the Tandem Repeat Protein 36 (TRP36) encoded by the trp36 gene. A total of 167 archived blood sam...
Source: Comparative Immunology, Microbiology and Infectious Diseases - February 11, 2019 Category: Infectious Diseases Source Type: research
An update on the treatment of canine monocytic ehrlichiosis (Ehrlichia canis)
Publication date: Available online 4 February 2019Source: The Veterinary JournalAuthor(s): Mathios E. Mylonakis, Shimon Harrus, Edward B. BreitschwerdtAbstractCanine monocytic ehrlichiosis (CME), caused by Ehrlichia canis, a gram-negative, obligate intracellular bacterium, is a tick-borne disease of worldwide distribution. Experimentally, the course of E. canis infection can be sequentially divided into acute, subclinical and chronic phases, although distinction of these phases is challenging in the clinical setting. Spontaneous clinical recovery of acutely infected dogs is common; however, dogs at this stage require medic...
Source: The Veterinary Journal - February 4, 2019 Category: Veterinary Research Source Type: research
Protection against canine vector-borne diseases using a monthly prevention of dinotefuran-permethrin-pyriproxyfen and milbemycine oxime
The objective of the study was the assessment of the preventive efficiency of a new prophylactic protocol against three major CVBD occurring in eastern coast of Corsica: monocytic ehrlichiosis, dirofilariosis and leishmaniosis. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - January 31, 2019 Category: Infectious Diseases Authors: Y. Laidoudi, H. Medkour, D. Tahir, J.-L. Mari é, M. Varloud, O. Mediannikov, B. Davoust Tags: 21.142 Source Type: research
Survey and Phylogenetic Analysis of Rodents and Important Rodent-Borne Zoonotic Pathogens in Gedu, Bhutan.
In this study, a cross-sectional investigation of zoonotic disease pathogens in rodents was performed in Chukha district, Bhutan, where a high incidence of scrub typhus and cases of acute undifferentiated febrile illness had been reported in people during the preceding 4-6 months. Twelve rodents were trapped alive using wire-mesh traps. Following euthanasia, liver and kidney tissues were removed and tested using PCR for Orientia tsutsugamushi and other bacterial and rickettsial pathogens causing bartonellosis, borreliosis, human monocytic ehrlichiosis, human granulocytic anaplasmosis, leptospirosis, and rickettsiosis. A ph...
Source: Korean Journal of Parasitology - November 15, 2018 Category: Parasitology Tags: Korean J Parasitol Source Type: research
Isolation and molecular detection of Ehrlichia species from ticks in western, central, and eastern Japan
In this study, the presence of Ehrlichia spp. in ticks in Japan was studied by using isolation and molecular detection methods. In total, 1,237 ticks were collected from vegetation in western, central, and eastern parts of Japan. The ticks were tested for detection of ehrlichial DNA with a nested polymerase chain reaction and/or isolation by inoculation of mice with the homogenate. Ehrlichial DNA was detected in 29 of these ticks. The ehrlichial DNAs, groEL and 16S rRNA genes, detected in Ixodes turdus showed a high similarity to those of E. chaffeensis with 94.7% and 99.2% identity, respectively. Ehrlichia sp. HF and Cand...
Source: Ticks and Tick borne Diseases - November 14, 2018 Category: Zoology Source Type: research
A Fatal Case of Hemophagocytic Lymphohistiocytosis in a Patient With Ehrlichiosis
We present a case of Ehrlichia-induced hemophagocytic lymphohistiocytosis (HLH), which resulted in a fatal outcome. Hemophagocytic lymphohistiocytosis is a rare syndrome of abnormal activation of the cellular immune system, which can be potentially fatal. Infections are a common trigger of the secondary form of the syndrome. We review the literature for published reports of Ehrlichia-induced HLH, all of which have resulted in a favorable outcome. We try to analyze the reasons for the poor outcome in our case including the possibility of central nervous system involvement with HLH. Early recognition and treatment of HLH and...
Source: Infectious Diseases in Clinical Practice - November 1, 2018 Category: Infectious Diseases Tags: Case Reports Source Type: research
