Tick-borne zoonoses in the Order Rickettsiales and Legionellales in Iran: A systematic review
ConclusionGiven the asymptomatic nature of some of these zoonoses, there is a high likelihood of silent transmission to humans in many parts of the country, which should be considered a public health concern. Presently, information on the transmission intensity of tick-borne zoonoses caused by pathogens in the Order Rickettsiales and Legionellales to humans and its public health impact in Iran is scanty. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - September 11, 2018 Category: Tropical Medicine Authors: Faham Khamesipour Source Type: research
Darbepoietin alpha ameliorates oxidative/nitrosative stress, decreases apoptosis, and improves clinical outcome in chronic canine monocytic ehrlichiosis
AbstractCanine monocytic ehrlichiosis (CME) is an important hemoprotozoan disease of dogs associated with anemia, leucopenia, and thrombocytopenia. The present study was conducted with the aim of assessing the status of oxidative/nitrosative stress and apoptosis in naturally occurring cases of chronic canine monocytic ehrlichiosis, to investigate potential of darbepoietin alpha in ameliorating oxidative/nitrosative stress and apoptosis associated with CME and to assess the impact of darbepoietin alpha administration on clinical outcome in chronic canine monocytic ehrlichiosis. Thirty naturally occurring cases of chronic CM...
Source: Comparative Clinical Pathology - September 7, 2018 Category: Pathology Source Type: research
Molecular survey and characterization of Theileria annulata and Ehrlichia ruminantium in cattle from Northwest China
In this study, a total of 176 blood samples of cattle from three rural areas of XUAR were collected in June 2017 and were tested by nested-PCR. A total of 34 (19.3%) samples were found to be infected with one or two pathogens. The overall prevalence rates of T. annulata and E. ruminantium were 18.2% and 1.7%, respectively. Phylogenetic analyses revealed that the E. ruminantium isolates from XUAR were located in the same clade but diverged from the isolates from African countries using pCS20 gene while T. annulata isolates from XUAR revealed differences in the genotypes using Tams1 sequences. To our knowledge, this is the f...
Source: Parasitology International - July 11, 2018 Category: Parasitology Source Type: research
Diagnosing Meat Allergy After Tick Bite Without Delay
Galactose-α-1, 3 galactose (α-gal) is a carbohydrate found in mammalian meat. In 2007, it was implicated as a cause of severe hypersensitivity reactions when a study found elevated levels of antibodies directed against this oligosaccharide among patients treated with cetuximab, a monoclonal antibody that contained an α -gal epitope. The majority of these cases were reported in the Southeast United States in a distribution similar to that of Rocky Mountain spotted fever and ehrlichiosis, and that geographic association led researchers to the conclusion that a bite from the Lone Star tick can induce this an...
Source: Journal of the American Board of Family Medicine - July 9, 2018 Category: Primary Care Authors: Kaplan, A. C., Carson, M. P. Tags: Brief Reports Source Type: research
Molecular survey and characterization of Theileria annulata and Ehrlichia ruminantium in cattle from Northwest China
In this study, a total of 176 blood samples of cattle from three rural areas of XUAR were collected in June 2017 and were tested by nested-PCR. A total of 34 (19.3%) samples were found to be infected with one or two pathogens. The overall prevalence rates of T. annulata and E. ruminantium were 18.2% and 1.7%, respectively. Phylogenetic analyses revealed that the E. ruminantium isolates from XUAR were located in the same clade but diverged from the isolates from African countries using pCS20 gene while T. annulata isolates from XUAR revealed differences in the genotypes using Tams1 sequences. To our knowledge, this is the f...
Source: Parasitology International - July 5, 2018 Category: Parasitology Source Type: research
Molecular survey and characterization of Theileria annulata and Ehrlichia ruminantium in cattle from Northwest China
In this study, a total of 176 blood samples of cattle from three rural areas of XUAR were collected in June 2017 and were tested by nested-PCR. A total of 34 (19.3%) samples were found to be infected with one or two pathogens. The overall prevalence rates of T. annulata and E. ruminantium were 18.2% and 1.7%, respectively. Phylogenetic analyses revealed that the E. ruminantium isolates from XUAR were found in the same clade but diverged from the isolates from African countries using pCS20 gene while T. annulata isolates from XUAR revealed differences in the genotypes using Tams1 sequences. To our knowledge, this is the fir...
Source: Parasitology International - June 28, 2018 Category: Parasitology Source Type: research
A new TaqMan method for the reliable diagnosis of Ehrlichia spp. in canine whole blood
Ehrlichiosis is an important emerging infectious disease of the canid family and humans worldwide. To date, no extensive evaluation or validation of a molecular diagnostic test for ehrlichiosis has been publis... (Source: Parasites and Vectors)
Source: Parasites and Vectors - June 18, 2018 Category: Microbiology Authors: Kirsty Thomson, Tal Yaaran, Alex Belshaw, Lucia Curson, Laurence Tisi, Sarah Maurice and Guy Kiddle Tags: Research Source Type: research
Two different genogroups of Ehrlichia canis from dogs in Thailand using immunodominant protein genes.
This study examined the molecular characteristics of E. canis using PCR and phylogenetic analysis of the dsb, gp19 and gp36 genes. DNA was extracted from 220 whole blood samples of naturally infected dogs, and all had clinical signs compatible with tick-borne diseases. Of these, 16.4% (36/220) provided positive E. canis DNA via the dsb and gp19 genes. However, only 13 out of the 36 samples (36.1%) were positive for the gp36 gene. Sequences of the dsb gene had very high identity (99-100%) with previously deposited E. canis sequences. Sequences of the gp19 gene were similar to those from US and Taiwanese genogroups (98.8-99....
Source: Infection, Genetics and Evolution - May 28, 2018 Category: Genetics & Stem Cells Authors: Nambooppha B, Rittipornlertrak A, Tattiyapong M, Tangtrongsup S, Tiwananthagorn S, Chung YT, Sthitmatee N Tags: Infect Genet Evol Source Type: research
Graft loss attributed to possible transfusion ‐transmitted ehrlichiosis following cord blood stem cell transplant
Transplant Infectious Disease, EarlyView. (Source: Transplant Infectious Disease)
Source: Transplant Infectious Disease - May 7, 2018 Category: Transplant Surgery Authors: Allison
Mah
,
George M.
Viola
,
Ella
Ariza Heredia
,
Katayoun
Rezvani
,
Partow
Kebriaei
,
Micah M.
Bhatti
,
Xin
Han
,
Elizabeth J.
Shpall
,
Victor E.
Mulanovich Source Type: research
Role and Function of the Type IV Secretion System in Anaplasma and Ehrlichia Species.
Authors: Rikihisa Y
Abstract
The obligatory intracellular pathogens Anaplasma phagocytophilum and Ehrlichia chaffeensis proliferate within membrane-bound vacuoles of human leukocytes and cause potentially fatal emerging infectious diseases. Despite the reductive genome evolution in this group of bacteria, genes encoding the type IV secretion system (T4SS), which is homologous to the VirB/VirD4 system of the plant pathogen Agrobacterium tumefaciens, have been expanded and are highly expressed in A. phagocytophilum and E. chaffeensis in human cells. Of six T4SS effector proteins identified in them, roles and...
Source: Current Topics in Microbiology and Immunology - March 16, 2018 Category: Microbiology Tags: Curr Top Microbiol Immunol Source Type: research
Detection and molecular characterisation of Ehrlichia canis in naturally infected dogs in South West Nigeria.
This study aimed to detect and characterise E. canis in dogs in Abeokuta, Nigeria by microscopy and nested PCR. Blood samples were collected from 205 dogs, thin smears were made, field-stained, and DNA was extracted from the blood samples. A partial region of the 16S rRNA gene was amplified by polymerase chain reaction (PCR) and sequenced unidirectionally. Ehrlichial morulae were detected in three dogs (1.5%). The PCR test revealed that 47 dogs (22.9%) were positive for E. canis. The lengths of the sequences obtained range from 374 bp to 376 bp with an average G-C content of 37% and 98-99% homology with the reference seque...
Source: Acta Veterinaria Hungarica - March 1, 2018 Category: Veterinary Research Authors: Daramola OO, Takeet MI, Oyewusi IK, Oyekunle MA, Talabi AO Tags: Acta Vet Hung Source Type: research
Pathogen transmission in relation to duration of attachment by Ixodes scapularis ticks
Publication date: Available online 31 January 2018 Source:Ticks and Tick-borne Diseases Author(s): Lars Eisen The blacklegged tick, Ixodes scapularis, is the primary vector to humans in the eastern United States of the deer tick virus lineage of Powassan virus (Powassan virus disease); the protozoan parasite Babesia microti (babesiosis); and multiple bacterial disease agents including Anaplasma phagocytophilum (anaplasmosis), Borrelia burgdorferi and Borrelia mayonii (Lyme disease), Borrelia miyamotoi (relapsing fever-like illness, named Borrelia miyamotoi disease), and Ehrlichia muris eauclairensis (a minor causative a...
Source: Ticks and Tick borne Diseases - January 31, 2018 Category: Zoology Source Type: research
The Blacklegged Tick, Ixodes scapularis: An Increasing Public Health Concern.
Abstract
In the United States, the blacklegged tick, Ixodes scapularis, is a vector of seven human pathogens, including those causing Lyme disease, anaplasmosis, babesiosis, Borrelia miyamotoi disease, Powassan virus disease, and ehrlichiosis associated with Ehrlichia muris eauclarensis. In addition to an accelerated rate of discovery of I. scapularis-borne pathogens over the past two decades, the geographic range of the tick, and incidence and range of I. scapularis-borne disease cases, have increased. Despite knowledge of when and where humans are most at risk of exposure to infected ticks, control of I....
Source: Trends in Parasitology - January 11, 2018 Category: Parasitology Authors: Eisen RJ, Eisen L Tags: Trends Parasitol Source Type: research
Relative Risk for Ehrlichiosis and Lyme Disease Where Vectors for Both Are Sympatric, Southeastern United States
M. E. Herman-Giddens (Source: Emerging Infectious Diseases Journal)
Source: Emerging Infectious Diseases Journal - January 4, 2018 Category: Infectious Diseases Source Type: research
