Canine infection with Dirofilaria immitis, Borrelia burgdorferi, Anaplasma spp., and Ehrlichia spp. in the United States, 2010-2012
The geographic distribution of canine vector-borne disease agents in the United States appears to be expanding. Monitoring canine test results is an important tool for accurately mapping the geographic distribution of these agents. Image: United States distribution maps for heartworm, Lyme disease, ehrlichiosis, and anaplasmosis. (Source: Parasites and Vectors)
Source: Parasites and Vectors - May 30, 2014 Category: Microbiology Authors: Susan LittleMelissa BeallDwight BowmanRamaswamy ChandrashekarJohn Stamaris Source Type: research
Intracytoplasmic granulocytic morulae counts on confirmed cases of ehrlichiosis/anaplasmosis in the northeast.
Conclusions Peripheral smears are a useful, cost-effective, and time-effective tool for diagnosing anaplasmosis. In positive cases, diagnostic morulae can be identified with a count of 200 granulocytes.
PMID: 24713739 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - April 12, 2014 Category: Pathology Authors: Rand JV, Tarasen AJ, Kumar J, Homan SM, Tobin E Tags: Am J Clin Pathol Source Type: research
A case of ocular canine transmissible venereal tumor.
Abstract
A 1-year-old, intact female mixed-breed dog was presented to St. George's University Small Animal Clinic in Grenada for a third eyelid mass. The dog was diagnosed with a rare ocular transmissible venereal tumor (TVT) and concurrent anaplasmosis, ehrlichiosis and dirofilariasis. Treatment with vincristine sulfate resulted in complete resolution of the TVT.
PMID: 24381345 [PubMed - in process] (Source: The Canadian Veterinary Journal)
Source: The Canadian Veterinary Journal - January 1, 2014 Category: Veterinary Research Authors: Milo J, Snead E Tags: Can Vet J Source Type: research
Myocarditis after trimethoprim/sulfamethoxazole treatment for ehrlichiosis.
We report a woman, 78 years of age, who was treated with trimethoprim/sulfamethoxazole after a tick bite, in whom myocarditis was subsequently diagnosed. She recovered completely after doxycycline therapy.
PMID: 24274783 [PubMed - in process] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - November 30, 2013 Category: Infectious Diseases Authors: Nayak SU, Simon GL Tags: Emerg Infect Dis Source Type: research
Usefulness of a rapid immuno-migration test for the detection of canine monocytic ehrlichiosis in Africa.
Abstract
A rapid immuno-migration test for the serological detection of canine monocytic ehrlichiosis, Witness(®) Ehrlichia (WE) (Zoetis, France), was evaluated in 528 serum samples from dogs living in endemic areas of West and East Africa: Senegal (N=208), Ivory Coast (N=7), Sudan (N=27), and Djibouti (N=286). Of these dogs, 200 were French military working dogs (MWD) temporarily residing in Africa. The WE test results were compared with those obtained by indirect immunofluorescence (IFA). The sensitivity of WE was 97% [94.2, 98.7] with a specificity of 100% [98.6, 100]. In MWD, the seroprevalence (IFA) ...
Source: Comparative immunology, microbiology and infectious diseases. - November 4, 2013 Category: Allergy & Immunology Authors: Davoust B, Parzy D, Demoncheaux JP, Tine R, Diarra M, Marié JL, Mediannikov O Tags: Comp Immunol Microbiol Infect Dis Source Type: research
Recombinant Ehrlichia P29 protein induces a protective immune response in a mouse model of ehrlichiosis.
In conclusion, our study indicated that orthologs of E. muris P29 showed considerable variation in the central tandem repeat region among different species, induction of P29-specific IgG antibody response was impaired during persistent E. muris infection, and rP29 induced protective immune responses.
PMID: 24144475 [PubMed - as supplied by publisher] (Source: Vaccine)
Source: Vaccine - October 18, 2013 Category: Allergy & Immunology Authors: Thirumalapura NR, Crocquet-Valdes PA, Saito TB, Thomas S, McBride JW, Walker DH Tags: Vaccine Source Type: research
SEROLOGICAL SURVEY OF Ehrlichia SPECIES IN DOGS, HORSES AND HUMANS: ZOONOTIC SCENERY IN A RURAL SETTLEMENT FROM SOUTHERN BRAZIL.
In conclusion, anti-Ehrlichia spp. antibodies were found in horses; however, the lack of a molecular characterization precludes any conclusion regarding the agent involved. Additionally, the higher seroprevalence of E. canis in dogs and the evidence of anti-Ehrlichia spp. antibodies in humans suggest that human cases of ehrlichiosis in Brazil might be caused by E. canis, or other closely related species.
PMID: 24037288 [PubMed - in process] (Source: Revista do Instituto de Medicina Tropical de Sao Paulo)
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - September 1, 2013 Category: Tropical Medicine Authors: Vieira RF, Vieira TS, Nascimento Ddo A, Martins TF, Krawczak FS, Labruna MB, Chandrashekar R, Marcondes M, Biondo AW, Vidotto O Tags: Rev Inst Med Trop Sao Paulo Source Type: research
Prevalence of borreliosis, anaplasmosis, ehrlichiosis and Dirofilaria immitis in dogs and vectors in Voronezh Reserve (Russia).
Abstract
Most of the dogs studied for the prevalence of CVBD have previously received acaricidal and insecticidal treatments. In the present work, a very specific population of dogs (Group 1) that had never been treated against ticks and mosquitoes was studied. Moreover, the territory occupied by this population has also never been treated, because it is a protected area - Voronezh Natural Reserve. Canine patients from veterinary clinics (Group 2) that had been treated against VBD vectors were studied for comparison. Eighty-two dogs (Group 1) were enrolled in June, 2008. Blood samples were tested using the...
Source: Comparative immunology, microbiology and infectious diseases. - August 30, 2013 Category: Allergy & Immunology Authors: Volgina NS, Romashov BV, Romashova NB, Shtannikov AV Tags: Comp Immunol Microbiol Infect Dis Source Type: research
Study of ehrlichiosis in kennel dogs under treatment and prevention during seven months in Dakar (Senegal).
Abstract
In Dakar kennels where morbidity and mortality attributed to diseases transmitted by ticks were high, we conducted a field study to assess the prevalence of Ehrlichia canis, Anaplasma platys and Babesia spp. infections in two kennels (n=34 dogs) and to study the impact of tick protection. The first day of the study, the E. canis PCR were positive in 18 dogs (53%). A. platys was found in one dog and all dogs were negative for Babesia spp. After one month of doxycycline treatment, the number of PCR positive dogs decreased significantly to 2 (5.9%). During seven months, all dogs were treated monthly ...
Source: Comparative immunology, microbiology and infectious diseases. - August 22, 2013 Category: Allergy & Immunology Authors: Davoust B, Mediannikov O, Chene J, Massot R, Tine R, Diarra M, Demoncheaux JP, Scandola P, Beugnet F, Chabanne L Tags: Comp Immunol Microbiol Infect Dis Source Type: research
Efficacy of rifampicin in the treatment of experimental acute canine monocytic ehrlichiosis
Conclusions
The rifampicin treatment regimen applied in this study hastened haematological recovery, but was inconsistent in eliminating the acute E. canis infection. (Source: Journal of Antimicrobial Chemotherapy)
Source: Journal of Antimicrobial Chemotherapy - June 14, 2013 Category: Microbiology Authors: Theodorou, K., Mylonakis, M. E., Siarkou, V. I., Leontides, L., Koutinas, A. F., Koutinas, C. K., Kritsepi-Konstantinou, M., Batzias, G., Flouraki, E., Eyal, O., Kontos, V., Harrus, S. Tags: Original research Source Type: research
Seropositivity rates for agents of canine vector-borne diseases in Spain: a multicentre study
This study determines seropositivity rates in Spain for agents causing the following five CVBD using two commercial in-clinic enzyme-linked immunosorbent assay kits: leishmaniosis, heartworm, ehrlichiosis, anaplasmosis and Lyme disease. Image: CVBD prevalences recorded for seven Spanish geographical regions. (Source: Parasites and Vectors)
Source: Parasites and Vectors - April 22, 2013 Category: Microbiology Authors: Guadalupe MiróAna MontoyaXavier RouraRosa GálvezAngel Sainz Source Type: research
Molecular evidence of Ehrlichia canis and Rickettsia massiliae in ixodid ticks of carnivores from South Hungary.
Abstract
To monitor the emergence of thermophilic, Mediterranean ixodid tick species and tick-borne pathogens in southern Hungary, 348 ticks were collected from shepherd dogs, red foxes and golden jackals during the summer of 2011. Golden jackals shared tick species with both the dog and the red fox in the region. Dermacentor nymphs were collected exclusively from dogs, and the sequence identification of these ticks indicated that dogs are preferred hosts of both D. reticulatus and D. marginatus nymphs, unlike previously reported. Subadults of three ixodid species were selected for reverse line blot hybrid...
Source: Acta Veterinaria Hungarica - March 1, 2013 Category: Veterinary Research Authors: Hornok S, Fuente J, Horváth G, Fernández de Mera IG, Wijnveld M, Tánczos B, Farkas R, Jongejan F Tags: Acta Vet Hung Source Type: research
The tick that stopped the ticker
A 31 year old healthy male was brought to emergency department after he collapsed while attending a bingo tournament. He denied any chest pain, shortness of breath or palpitations. The witnesses of event reported no incontinence, tongue bite or jerky movements of body. Patient had no recollection of event and was asymptomatic at presentation. Patient reported being in the woods for last few days and developing malaise and generalized weakness 3days prior to this event. The patient was awake, alert and oriented to time, place and person. His vital signs and cardiovascular examination were unremarkable. His laboratory data r...
Source: International Journal of Cardiology - February 14, 2013 Category: Cardiology Authors: Saeed Ahmed, Supawat Ratanapo, Patompong Ungprasert, Wisit Cheungpasitporn, Edward F. Bischof Tags: Online Letters to the Editor Source Type: research
Ehrlichia chaffeensis replication sites in adult Drosophila melanogaster.
Abstract
Ehrlichia chaffeensis is a Gram-negative, obligate intracellular bacterium which causes the tick-borne disease human monocytic ehrlichiosis. In vertebrates, E. chaffeensis replicates in monocytes and macrophages. However, no clear cell or tissue tropism has been defined in arthropods. Our group identified two host genes that control E. chaffeensis replication and infection in vivo in Drosophila, Uridine cytidine kinase and separation anxiety. Using the UAS-GAL4 RNAi system, we generated F1 flies (UAS-gene of interestRNAi x tissue-GAL4 flies) that have Uck2 or san silenced in ubiquitous or tissue-s...
Source: International Journal of Medical Microbiology - January 7, 2013 Category: Microbiology Authors: Drolia R, Von Ohlen T, Chapes SK Tags: Int J Med Microbiol Source Type: research
Multiple myeloma in a dog with multiple concurrent infectious diseases and persistent polyclonal gammopathy
Abstract
A 12‐year‐old, spayed female, mixed‐breed dog was presented for acute hematuria, stranguria, polyuria, and polydipsia, as well as lameness for 8 days. Previous medical history included treatment for infection with Ehrlichia canis, Anaplasma phagocytophilum, Leishmania infantum, and Dirofilaria immitis 6.5 years prior to presentation. Besides persistently increased antibody titers to E canis and A phagocytophilum, polyclonal gammopathy with a monoclonal spike and moderate hypercalcemia were observed. There was marked hematuria, and Staphylococcus aureus was cultured from urine. Two weeks after successful ...
Source: Veterinary Clinical Pathology - December 31, 2012 Category: Veterinary Research Authors: Caroline Geigy, Barbara Riond, Carla Rohrer Bley, Paula Grest, Patrick Kircher, Hans Lutz Tags: Case Report Source Type: research
