Ocular Spiroplasma ixodetis in Newborns, France.
, Cassoux N Abstract Cataract and uveitis are rare in newborns but potentially blinding. Three newborns with cataract and severe anterior uveitis underwent cataract surgery. Spiroplasma ixodetis was detected in lens aspirates using bacterial 16S-rRNA PCR and transmission electron microscopy. These findings, which suggest maternal-fetal infection, are consistent with previous experimental Spiroplasma-induced cataract and uveitis. PMID: 31793858 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - December 5, 2019 Category: Infectious Diseases Authors: Matet A, Le Flèche-Matéos A, Doz F, Dureau P, Cassoux N Tags: Emerg Infect Dis Source Type: research

In Memoriam: Jay Stephen Keystone (1943-2019).
PMID: 31693477 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - November 8, 2019 Category: Infectious Diseases Authors: Freedman DO Tags: Emerg Infect Dis Source Type: research

Hantavirus Pulmonary Syndrome in Traveler Returning from Nepal to Spain.
We describe a case of hantavirus pulmonary syndrome in a previously healthy traveler occurring shortly after he returned to Spain from Nepal. Serologic tests suggested a Puumala virus-like infection. PMID: 31674901 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - November 2, 2019 Category: Infectious Diseases Authors: Sulleiro E, Aznar ML, Serre-Delcor N, Salvador F, Sanchez-Montalvá A, Espasa M, Molina D, de Ory F, Sanchez-Seco MP, Molina I, Diaz-Lagares C, Martinez MJ, Pumarola T, Oliveira I Tags: Emerg Infect Dis Source Type: research

Tick-Borne Encephalitis Virus, United Kingdom.
Abstract During February 2018-January 2019, we conducted large-scale surveillance for the presence and prevalence of tick-borne encephalitis virus (TBEV) and louping ill virus (LIV) in sentinel animals and ticks in the United Kingdom. Serum was collected from 1,309 deer culled across England and Scotland. Overall, 4% of samples were ELISA-positive for the TBEV serocomplex. A focus in the Thetford Forest area had the highest proportion (47.7%) of seropositive samples. Engorged ticks collected from culled deer within seropositive regions were tested for viral RNA; 5 of 2,041 ticks tested positive by LIV/TBEV real-ti...
Source: Emerging Infectious Diseases - October 30, 2019 Category: Infectious Diseases Authors: Holding M, Dowall SD, Medlock JM, Carter DP, Pullan ST, Lewis J, Vipond R, Rocchi MS, Baylis M, Hewson R Tags: Emerg Infect Dis Source Type: research

Locally Acquired Human Infection with Swine-Origin Influenza A(H3N2) Variant Virus, Australia, 2018.
Abstract In 2018, a 15-year-old female adolescent in Australia was infected with swine influenza A(H3N2) variant virus. The virus contained hemagglutinin and neuraminidase genes derived from 1990s-like human seasonal viruses and internal protein genes from influenza A(H1N1)pdm09 virus, highlighting the potential risk that swine influenza A virus poses to human health in Australia. PMID: 31661057 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - October 30, 2019 Category: Infectious Diseases Authors: Deng YM, Wong FYK, Spirason N, Kaye M, Beazley R, Grau M, Shan S, Stevens V, Subbarao K, Sullivan S, Barr IG, Dhanasekaran V Tags: Emerg Infect Dis Source Type: research

Effect of Pediatric Influenza Vaccination on Antibiotic Resistance, England and Wales.
Abstract Vaccines against viral infections have been proposed to reduce prescribing of antibiotics and thereby help control resistant bacterial infections. However, by combining published data sources, we predict that pediatric live attenuated influenza vaccination in England and Wales will not substantially reduce antibiotic consumption or adverse health outcomes associated with antibiotic resistance. PMID: 31574242 [PubMed - in process] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - October 3, 2019 Category: Infectious Diseases Authors: Chae C, Davies NG, Jit M, Atkins KE Tags: Emerg Infect Dis Source Type: research

Half-Life of African Swine Fever Virus in Shipped Feed.
Abstract African swine fever virus is transmissible through animal consumption of contaminated feed. To determine virus survival during transoceanic shipping, we calculated the half-life of the virus in 9 feed ingredients exposed to 30-day shipment conditions. Half-lives ranged from 9.6 to 14.2 days, indicating that the feed matrix environment promotes virus stability. PMID: 31524583 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - September 18, 2019 Category: Infectious Diseases Authors: Stoian AMM, Zimmerman J, Ji J, Hefley TJ, Dee S, Diel DG, Rowland RRR, Niederwerder MC Tags: Emerg Infect Dis Source Type: research

Drug-Susceptible and Multidrug-Resistant Mycobacterium tuberculosis in a Single Patient.
Abstract A patient who had initial infection with mixed strains of drug-susceptible and multidrug-resistant tuberculosis was presumed to have acquired drug resistance before confirmation that sequential strains were genotypically distinct. Transmitted infection with mixed strains is likely underappreciated; identifying these infections requires spoligotyping and whole-genome sequencing. PMID: 31454310 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - August 29, 2019 Category: Infectious Diseases Authors: Baffoe-Bonnie A, Houpt ER, Turner L, Dodge D, Heysell SK Tags: Emerg Infect Dis Source Type: research

Molecular and Clinical Comparison of Enterovirus D68 Outbreaks among Hospitalized Children, Ohio, USA, 2014 and 2018.
Abstract Enterovirus D68 (EV-D68) causes respiratory tract infections and neurologic manifestations. We compared the clinical manifestations from 2 EV-D68 outbreaks in 2014 and 2018 and a low-activity period in 2016 among hospitalized children in central Ohio, USA, and used PCR and sequencing to enable phylogenetic comparisons. During both outbreak periods, infected children had respiratory manifestations that led to an increase in hospital admissions for asthma. The 2018 EV-D68 outbreak appeared to be milder in terms of respiratory illness, as shown by lower rates of pediatric intensive care unit admission. Howev...
Source: Emerging Infectious Diseases - August 29, 2019 Category: Infectious Diseases Authors: Wang H, Diaz A, Moyer K, Mele-Casas M, Ara-Montojo MF, Torrus I, McCoy K, Mejias A, Leber AL Tags: Emerg Infect Dis Source Type: research

Human-to-Human Transmission of Influenza A(H3N2) Virus with Reduced Susceptibility to Baloxavir, Japan, February 2019.
Abstract In 2019, influenza A(H3N2) viruses carrying an I38T substitution in the polymerase acidic gene, which confers reduced susceptibility to baloxavir, were detected in Japan in an infant without baloxavir exposure and a baloxavir-treated sibling. These viruses' whole-genome sequences were identical, indicating human-to-human transmission. Influenza virus isolates should be monitored for baloxavir susceptibility. PMID: 31436527 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - August 23, 2019 Category: Infectious Diseases Authors: Takashita E, Ichikawa M, Morita H, Ogawa R, Fujisaki S, Shirakura M, Miura H, Nakamura K, Kishida N, Kuwahara T, Sugawara H, Sato A, Akimoto M, Mitamura K, Abe T, Yamazaki M, Watanabe S, Hasegawa H, Odagiri T Tags: Emerg Infect Dis Source Type: research

Macrolide-Resistant Mycoplasma genitalium in Southeastern Region of the Netherlands, 2014-2017.
eta C PMID: 31436528 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - August 23, 2019 Category: Infectious Diseases Authors: Adelantado M, Navascués A, Beristain X, Gil-Setas A, Portillo ME, Aguinaga A, Ezpeleta C Tags: Emerg Infect Dis Source Type: research

Middle East Respiratory Syndrome Coronavirus, Saudi Arabia, 2017-2018.
Abstract We characterized exposures and demographics of Middle East respiratory syndrome coronavirus cases reported to the Saudi Arabia Ministry of Health during July 1-October 31, 2017, and June 1-September 16, 2018. Molecular characterization of available specimens showed that lineage 5 predominated among circulating viruses during these periods. PMID: 31430248 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - August 22, 2019 Category: Infectious Diseases Authors: Hakawi A, Rose EB, Biggs HM, Lu X, Mohammed M, Abdalla O, Abedi GR, Alsharef AA, Alamri AA, Bereagesh SA, Al Dosari KM, Ashehri SA, Fakhouri WG, Alzaid SZ, Lindstrom S, Gerber SI, Asiri A, Jokhdar H, Watson JT Tags: Emerg Infect Dis Source Type: research

Comparison of Serologic Assays for Middle East Respiratory Syndrome Coronavirus.
We describe a collaborative study to investigate the comparability of serologic assays for MERS-CoV and assess any benefit associated with the introduction of a standard reference reagent for MERS-CoV serology. Our study findings indicate that, when possible, laboratories should use a testing algorithm including>2 tests to ensure correct diagnosis of MERS-CoV. We also demonstrate that the use of a reference reagent greatly improves the agreement between assays, enabling more consistent and therefore more meaningful comparisons between results. PMID: 31423969 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - August 20, 2019 Category: Infectious Diseases Authors: Harvey R, Mattiuzzo G, Hassall M, Sieberg A, Müller MA, Drosten C, Rigsby P, Oxenford CJ, study participants Tags: Emerg Infect Dis Source Type: research

Sensitive and Specific Detection of Low-Level Antibody Responses in Mild Middle East Respiratory Syndrome Coronavirus Infections.
Abstract Middle East respiratory syndrome coronavirus (MERS-CoV) infections in humans can cause asymptomatic to fatal lower respiratory lung disease. Despite posing a probable risk for virus transmission, asymptomatic to mild infections can go unnoticed; a lack of seroconversion among some PCR-confirmed cases has been reported. We found that a MERS-CoV spike S1 protein-based ELISA, routinely used in surveillance studies, showed low sensitivity in detecting infections among PCR-confirmed patients with mild clinical symptoms and cross-reactivity of human coronavirus OC43-positive serum samples. Using in-house S1 ELI...
Source: Emerging Infectious Diseases - August 20, 2019 Category: Infectious Diseases Authors: Okba NMA, Raj VS, Widjaja I, Geurts van Kessel CH, de Bruin E, Chandler FD, Park WB, Kim NJ, Farag EABA, Al-Hajri M, Bosch BJ, Oh MD, Koopmans MPG, Reusken CBEM, Haagmans BL Tags: Emerg Infect Dis Source Type: research

Transmissibility of MERS-CoV Infection in Closed Setting, Riyadh, Saudi Arabia, 2015.
Abstract To investigate a cluster of Middle East respiratory syndrome (MERS) cases in a women-only dormitory in Riyadh, Saudi Arabia, in October 2015, we collected epidemiologic information, nasopharyngeal/oropharyngeal swab samples, and blood samples from 828 residents during November 2015 and December 2015-January 2016. We found confirmed infection for 19 (8 by reverse transcription PCR and 11 by serologic testing). Infection attack rates varied (2.7%-32.3%) by dormitory building. No deaths occurred. Independent risk factors for infection were direct contact with a confirmed case-patient and sharing a room with ...
Source: Emerging Infectious Diseases - August 20, 2019 Category: Infectious Diseases Authors: Van Kerkhove MD, Aswad S, Assiri A, Perera RAPM, Peiris M, El Bushra HE, Abdulaziz A. BinSaeed Tags: Emerg Infect Dis Source Type: research

Lassa Virus in Pygmy Mice, Benin, West Africa, 2016-2017.
Fichet-Calvet E Abstract Lassa virus has been identified in 3 pygmy mice, Mus baoulei, in central Benin. The glycoprotein and nucleoprotein sequences cluster with the Togo strain. These mice may be a new reservoir for Lassa virus in Ghana, Togo, and Benin. PMID: 31365854 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - August 2, 2019 Category: Infectious Diseases Authors: Yadouleton A, Agolinou A, Kourouma F, Saizonou R, Pahlmann M, Bedié SK, Bankolé H, Becker-Ziaja B, Gbaguidi F, Thielebein A, Magassouba N, Duraffour S, Baptiste JP, Günther S, Fichet-Calvet E Tags: Emerg Infect Dis Source Type: research

Emergence of Influenza A(H7N4) Virus, Cambodia.
Abstract Active surveillance in high-risk sites in Cambodia has identified multiple low-pathogenicity influenza A(H7) viruses, mainly in ducks. None fall within the A/Anhui/1/2013(H7N9) lineage; however, some A(H7) viruses from 2018 show temporal and phylogenetic similarity to the H7N4 virus that caused a nonfatal infection in Jiangsu Province, China, in December 2017. PMID: 31310233 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - July 18, 2019 Category: Infectious Diseases Authors: Vijaykrishna D, Deng YM, Grau ML, Kay M, Suttie A, Horwood PF, Kalpravidh W, Claes F, Osbjer K, Dussart P, Barr IG, Karlsson EA Tags: Emerg Infect Dis Source Type: research

Susceptibility of Influenza A, B, C, and D Viruses to Baloxavir1.
Abstract Baloxavir showed broad-spectrum in vitro replication inhibition of 4 types of influenza viruses (90% effective concentration range 1.2-98.3 nmol/L); susceptibility pattern was influenza A ˃ B ˃ C ˃ D. This drug also inhibited influenza A viruses of avian and swine origin, including viruses that have pandemic potential and those resistant to neuraminidase inhibitors. PMID: 31287050 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - July 11, 2019 Category: Infectious Diseases Authors: Mishin VP, Patel MC, Chesnokov A, De La Cruz J, Nguyen HT, Lollis L, Hodges E, Jang Y, Barnes J, Uyeki T, Davis CT, Wentworth DE, Gubareva LV Tags: Emerg Infect Dis Source Type: research

Worldwide Reduction in MERS Cases and Deaths since 2016.
Abstract Since 2012, Middle East respiratory syndrome (MERS) coronavirus has infected 2,442 persons worldwide. Case-based data analysis suggests that since 2016, as many as 1,465 cases and 293-520 deaths might have been averted. Efforts to reduce the global MERS threat are working, but countries must maintain vigilance to prevent further infections. PMID: 31264567 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - July 4, 2019 Category: Infectious Diseases Authors: Donnelly CA, Malik MR, Elkholy A, Cauchemez S, Van Kerkhove MD Tags: Emerg Infect Dis Source Type: research

Estimated Incubation Period and Serial Interval for Human-to-Human Influenza A(H7N9) Virus Transmission.
Abstract We estimated the incubation period and serial interval for human-to-human-transmitted avian influenza A(H7N9) virus infection using case-patient clusters from epidemics in China during 2013-2017. The median incubation period was 4 days and serial interval 9 days. China's 10-day monitoring period for close contacts of case-patients should detect most secondary infections. PMID: 31264568 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - July 4, 2019 Category: Infectious Diseases Authors: Zhou L, Li Q, Uyeki TM Tags: Emerg Infect Dis Source Type: research

Soft Tissue Infection with Diaporthe phaseolorum in Heart Transplant Recipient with End-Stage Renal Failure.
We report a case of human soft tissue infection with Diaporthe phaseolorum in a heart transplant patient with end-stage renal failure in New Zealand. PMID: 31237834 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - June 28, 2019 Category: Infectious Diseases Authors: Howard JC, Chen K, Werno A, Metcalf S Tags: Emerg Infect Dis Source Type: research

Theileria orientalis Ikeda Genotype in Cattle, Virginia, USA.
Abstract Theileria orientalis Ikeda genotype is a parasite that causes a disease in cattle that results in major economic issues in Asia, New Zealand, and Australia. The parasite is transmitted by Haemaphysalis longicornis ticks, which have recently been reported in numerous states throughout the eastern United States. Concurrently, cattle in Virginia showed clinical signs consistent with a hemoprotozoan infection. We used amplicons specific for the major piroplasm surface protein and small subunit rDNA of piroplasms to test blood samples from the cattle by PCR. Bidirectional Sanger sequencing showed sequences wit...
Source: Emerging Infectious Diseases - June 28, 2019 Category: Infectious Diseases Authors: Oakes VJ, Yabsley MJ, Schwartz D, LeRoith T, Bissett C, Broaddus C, Schlater JL, Todd SM, Boes KM, Brookhart M, Lahmers KK Tags: Emerg Infect Dis Source Type: research

Dengue Virus Type 1 Infection in Traveler Returning from Tanzania to Japan, 2019.
Abstract The largest outbreak of dengue fever in Tanzania is ongoing. Dengue virus type 1 was diagnosed in a traveler who returned from Tanzania to Japan. In phylogenetic analysis, the detected strain was close to the Singapore 2015 strain, providing a valuable clue for investigating the dengue outbreak in Tanzania. PMID: 31237836 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - June 28, 2019 Category: Infectious Diseases Authors: Okada K, Morita R, Egawa K, Hirai Y, Kaida A, Shirano M, Kubo H, Goto T, Yamamoto SP Tags: Emerg Infect Dis Source Type: research

Delays in Coccidioidomycosis Diagnosis and Relationship to Healthcare Utilization, Arizona, USA1.
Abstract We developed an electronic records methodology to programmatically estimate the date of first appearance of coccidioidomycosis symptoms in patients. We compared the diagnostic delay with overall healthcare utilization charges. Many patients (46%) had delays in diagnosis of>1 month. Billed healthcare charges before diagnosis increased with length of delay. PMID: 31228403 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - June 24, 2019 Category: Infectious Diseases Authors: Ginn R, Mohty R, Bollmann K, Goodsell J, Mendez G, Bradley B, Galgiani JN Tags: Emerg Infect Dis Source Type: research

Candida auris in Germany and Previous Exposure to Foreign Healthcare.
We report on 7 cases identified in Germany during 2015-2017. In 6 of these cases, C. auris was isolated from patients previously hospitalized abroad. Whole-genome sequencing and epidemiologic analyses revealed that all patients in Germany were infected with different strains. PMID: 31223105 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - June 23, 2019 Category: Infectious Diseases Authors: Hamprecht A, Barber AE, Mellinghoff SC, Thelen P, Walther G, Yu Y, Neurgaonkar P, Dandekar T, Cornely OA, Martin R, Kurzai O, German Candida auris Study Group1 Tags: Emerg Infect Dis Source Type: research

Crimean-Congo Hemorrhagic Fever, Herat Province, Afghanistan, 2017.
Abstract We studied the clinical and epidemiologic features of an outbreak of Crimean-Congo hemorrhagic fever in Herat Province, Afghanistan. The study comprised 63 patients hospitalized in 2017. The overall case-fatality rate was 22.2%; fatal outcome was significantly associated with a negative IgM test result, longer prothrombin time, and nausea. PMID: 31216260 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - June 21, 2019 Category: Infectious Diseases Authors: Niazi AU, Jawad MJ, Amirnajad A, Durr PA, Williams DT Tags: Emerg Infect Dis Source Type: research

Intrafamily Transmission of Monkeypox Virus, Central African Republic, 2018.
We report an investigation of a monkeypox outbreak in Lobaye, in southwest region of Central African Republic, in October 2018. PMID: 31216261 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - June 21, 2019 Category: Infectious Diseases Authors: Besombes C, Gonofio E, Konamna X, Selekon B, Grant R, Gessain A, Berthet N, Manuguerra JC, Fontanet A, Nakouné E Tags: Emerg Infect Dis Source Type: research

Emergent Invasive Group A Streptococcus dysgalactiae subsp. Equisimilis, United States, 2015-2018.
We describe an emergent invasive S. dysgalactiae subspecies equisimilis lineage that obtained the group A antigen through a single ancestral recombination event between a group C S. dysgalactiae subsp. equisimilis strain and group A S. pyogenes strain. PMID: 31158071 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - June 4, 2019 Category: Infectious Diseases Authors: Chochua S, Rivers J, Mathis S, Li Z, Velusamy S, McGee L, Van Beneden C, Li Y, Metcalf BJ, Beall B Tags: Emerg Infect Dis Source Type: research

Polio-like Manifestation of Powassan Virus Infection with Anterior Horn Cell Involvement, Canada.
We report a case of a polio-like illness caused by Powassan virus infection in a 62-year-old man in Canada. Magnetic resonance imaging showed T2 hyperintensities in the anterior horns of the cervical spinal cord. PMID: 31158072 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - June 4, 2019 Category: Infectious Diseases Authors: Picheca C, Yogendrakumar V, Brooks JI, Torres C, Pringle E, Zwicker J Tags: Emerg Infect Dis Source Type: research

Early Questing by Lone Star Tick Larvae, New York and Massachusetts, USA, 2018.
Abstract Subtropical lone star tick larvae typically emerge in late summer. We found clusters of host-seeking lone star tick larvae during early June 2018 in New York and Massachusetts, USA. Invasion and persistence of this tick in more northern locations may have been promoted by adaptation to an accelerated life cycle. PMID: 31146799 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - June 1, 2019 Category: Infectious Diseases Authors: Telford SR, Buchthal J, Elias P Tags: Emerg Infect Dis Source Type: research

Marburgvirus in Egyptian Fruit Bats, Zambia.
Abstract We detected Marburg virus genome in Egyptian fruit bats (Rousettus aegyptiacus) captured in Zambia in September 2018. The virus was closely related phylogenetically to the viruses that previously caused Marburg outbreaks in the Democratic Republic of the Congo. This finding demonstrates that Zambia is at risk for Marburg virus disease. PMID: 31146800 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - June 1, 2019 Category: Infectious Diseases Authors: Kajihara M, Hang'ombe BM, Changula K, Harima H, Isono M, Okuya K, Yoshida R, Mori-Kajihara A, Eto Y, Orba Y, Ogawa H, Qiu Y, Sawa H, Simulundu E, Mwizabi D, Munyeme M, Squarre D, Mukonka V, Mweene A, Takada A Tags: Emerg Infect Dis Source Type: research

Evaluating Temperature Sensitivity of Vesicular Stomatitis Virus-Based Vaccines.
Abstract Use of the vesicular stomatitis virus (VSV)-based Ebola virus vaccine during outbreaks and the potential use of a similar VSV-based Lassa virus vaccine has raised questions about the vaccines' stability should the cold chain fail. We demonstrated that current cold chain condition might tolerate significant variances without affecting efficacy. PMID: 31141474 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - May 31, 2019 Category: Infectious Diseases Authors: Stein DR, Sroga P, Warner BM, Deschambault Y, Poliquin G, Safronetz D Tags: Emerg Infect Dis Source Type: research

Cross-Protection of Dengue Virus Infection against Congenital Zika Syndrome, Northeastern Brazil.
JF Abstract The Zika virus outbreak in Latin America resulted in congenital malformations, called congenital Zika syndrome (CZS). For unknown reasons, CZS incidence was highest in northeastern Brazil; one potential explanation is that dengue virus (DENV)-mediated immune enhancement may promote CZS development. In contrast, our analyses of historical DENV genomic data refuted the hypothesis that unique genome signatures for northeastern Brazil explain the uneven dispersion of CZS cases. To confirm our findings, we performed serotype-specific DENV neutralization tests in a case-control framework in northeastern Bra...
Source: Emerging Infectious Diseases - May 12, 2019 Category: Infectious Diseases Authors: Pedroso C, Fischer C, Feldmann M, Sarno M, Luz E, Moreira-Soto A, Cabral R, Netto EM, Brites C, Kümmerer BM, Drexler JF Tags: Emerg Infect Dis Source Type: research

Outbreak of African Swine Fever, Vietnam, 2019.
Abstract African swine fever is one of the most dangerous diseases of swine. We confirmed the 2019 outbreak in Vietnam by real-time reverse transcription PCR. The causative strain belonged to p72 genotype II and was 100% identical with viruses isolated in China (2018) and Georgia (2007). International prevention and control collaboration is needed. PMID: 31075078 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - May 12, 2019 Category: Infectious Diseases Authors: Le VP, Jeong DG, Yoon SW, Kwon HM, Trinh TBN, Nguyen TL, Bui TTN, Oh J, Kim JB, Cheong KM, Van Tuyen N, Bae E, Vu TTH, Yeom M, Na W, Song D Tags: Emerg Infect Dis Source Type: research

Increased Threat of Urban Malaria from Anopheles stephensi Mosquitoes, Africa.
Abstract Malaria continues to be a major health threat in Africa, mainly in rural areas. Recently, the urban malaria vector Anopheles stephensi invaded Djibouti and Ethiopia, potentially spreading to other areas of Africa. Urgent action is needed to prevent urban malaria epidemics from emerging and causing a public health disaster. PMID: 31063455 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - May 8, 2019 Category: Infectious Diseases Authors: Takken W, Lindsay S Tags: Emerg Infect Dis Source Type: research

Whole-Blood Testing for Diagnosis of Acute Zika Virus Infections in Routine Diagnostic Setting.
Abstract We evaluated the benefit of whole blood versus plasma to detect acute Zika virus infections. Comparison of Zika virus quantitative reverse transcription PCR results in single timepoint whole blood-plasma pairs from 227 patients with suspected Zika virus infection resulted in confirmation of 8 additional patients with Zika virus infection. PMID: 31008703 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - April 24, 2019 Category: Infectious Diseases Authors: Voermans JJC, Pas SD, van der Linden A, van Kessel CG, Koopmans M, van der Eijk A, Reusken CBEM Tags: Emerg Infect Dis Source Type: research

Dengue Outbreak during Ongoing Civil War, Taiz, Yemen.
Abstract We identified dengue in ≈51% of patients given a clinical diagnosis of suspected dengue in Taiz, Yemen, during 2016. The cosmopolitan genotype of dengue virus type 2 was most common; viruses appeared to have originated in Saudi Arabia. Damage to public health infrastructure during ongoing civil war might enable dengue to become endemic to Yemen. PMID: 30924766 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - March 31, 2019 Category: Infectious Diseases Authors: Alghazali KA, Teoh BT, Loong SK, Sam SS, Che-Mat-Seri NA, Samsudin NI, Yaacob CN, Azizan NS, Oo A, Baharudin NA, Tan KK, Abd-Jamil J, Nor'e SS, Khor CS, Johari J, Mahdy MAK, AbuBakar S Tags: Emerg Infect Dis Source Type: research

Molecular Evidence of Human Monkeypox Virus Infection, Sierra Leone.
Abstract Monkeypox virus is a zoonotic disease endemic to Africa. In 2017, we confirmed a case of human monkeypox virus in Sierra Leone by molecular and serologic methods. Sequencing analysis indicated the virus belongs to the West African clade and data suggest it was likely transmitted by wild animals. PMID: 30900976 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - March 23, 2019 Category: Infectious Diseases Authors: Ye F, Song J, Zhao L, Zhang Y, Xia L, Zhu L, Kamara IL, Ren J, Wang W, Tian H, Wu G, Tan W Tags: Emerg Infect Dis Source Type: research

Sequential Emergence and Wide Spread of Neutralization Escape Middle East Respiratory Syndrome Coronavirus Mutants, South Korea, 2015.
Abstract The unexpectedly large outbreak of Middle East respiratory syndrome in South Korea in 2015 was initiated by an infected traveler and amplified by several "superspreading" events. Previously, we reported the emergence and spread of mutant Middle East respiratory syndrome coronavirus bearing spike mutations (I529T or D510G) with reduced affinity to human receptor CD26 during the outbreak. To assess the potential association of spike mutations with superspreading events, we collected virus genetic information reported during the outbreak and systemically analyzed the relationship of spike sequences...
Source: Emerging Infectious Diseases - March 23, 2019 Category: Infectious Diseases Authors: Kim YS, Aigerim A, Park U, Kim Y, Rhee JY, Choi JP, Park WB, Park SW, Kim Y, Lim DG, Inn KS, Hwang ES, Choi MS, Shin HS, Cho NH Tags: Emerg Infect Dis Source Type: research

Suboptimal Handling of Piccolo Samples or Reagent Discs for Consideration in Ebola Response.
Abstract Operating clinical analyzers within recommended parameters can be challenging during outbreak response. Using the Piccolo Xpress point-of-care blood chemistry analyzer on guinea pig blood, we found that values of many analytes are still readily comparable when samples and reagent discs are handled at various conditions outside of manufacturer's recommendations. PMID: 30900978 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - March 23, 2019 Category: Infectious Diseases Authors: Spengler JR, Welch SR, Genzer SC, Coleman-McCray J, Harmon JR, Nichol ST, Spiropoulou CF Tags: Emerg Infect Dis Source Type: research

Identification of Internationally Disseminated Ceftriaxone-Resistant Neisseria gonorrhoeae Strain FC428, China.
Abstract In 2016, we identified a ceftriaxone-resistant Neisseria gonorrhoeae isolate in China. The strain genotype was identical to the resistant clone FC428 that originated in Japan. Enhanced international collaborative surveillance programs are crucial to track the transmission of the ceftriaxone-resistant clones. PMID: 30900979 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - March 23, 2019 Category: Infectious Diseases Authors: Chen SC, Han Y, Yuan LF, Zhu XY, Yin YP Tags: Emerg Infect Dis Source Type: research

Hepatitis Rebound after Infection with Yellow Fever Virus.
na JM Abstract In 2018, yellow fever with hepatitis was diagnosed for 2 unvaccinated travelers returning to France from Brazil. Hepatitis persisted for>6 months; liver enzyme levels again increased 2 months after disease onset with no detection of yellow fever virus RNA or other pathogens. Persistent hepatitis with hepatic cytolysis rebound probably resulted from immune response. PMID: 30870138 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - March 16, 2019 Category: Infectious Diseases Authors: Denis B, Chirio D, Ponscarme D, Brichler S, Colin de Verdière N, Simon F, Molina JM Tags: Emerg Infect Dis Source Type: research

Reemergence of Classical Swine Fever, Japan, 2018.
Abstract In September 2018, classical swine fever reemerged in Japan after 26 years, affecting domestic pigs and wild boars. The causative virus belongs to an emerging clade within the 2.1 subgenotype, which caused repeated outbreaks in eastern and Southeast Asia. Intensive surveillance of swine will help control and eradicate this disease in Japan. PMID: 30870139 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - March 16, 2019 Category: Infectious Diseases Authors: Postel A, Nishi T, Kameyama KI, Meyer D, Suckstorff O, Fukai K, Becher P Tags: Emerg Infect Dis Source Type: research

Increase in Enterovirus D68 Infections in Young Children, United Kingdom, 2006-2016.
Abstract We determined the change in seroprevalence of enterovirus D68 (EV-D68) in the United Kingdom in age-stratified cohorts from 2006 to 2016, the period during which EV-D68 emerged as a cause of severe respiratory disease occasionally leading to paralysis. Infections were acquired primarily in infants and young children, and incidence was markedly higher in 2016. PMID: 30855226 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - March 12, 2019 Category: Infectious Diseases Authors: Kamau E, Harvala H, Blomqvist S, Nguyen D, Horby P, Pebody R, Simmonds P Tags: Emerg Infect Dis Source Type: research

African Swine Fever Virus in Pork Brought into South Korea by Travelers from China, August 2018.
Abstract We tested samples of pork products confiscated from travelers to South Korea for African swine fever virus (ASFV). We detected ASFV in 4 food items confiscated from travelers from Shenyang, China, in August 2018. Surveillance of pork products at country entry points is needed to mitigate the risk for ASFV introduction. PMID: 30844357 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - March 9, 2019 Category: Infectious Diseases Authors: Kim HJ, Lee MJ, Lee SK, Kim DY, Seo SJ, Kang HE, Nam HM Tags: Emerg Infect Dis Source Type: research

Infection with New York Orthohantavirus and Associated Respiratory Failure and Multiple Cerebral Complications.
We report a case of infection with New York orthohantavirus in a woman who showed renal impairment and hemorrhage, complicated by hydrocephalus, in Long Island, New York, USA. Phylogenetic analysis showed that this virus was genetically similar to a New York orthohantavirus isolated in the same region during 1993. PMID: 30844358 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - March 9, 2019 Category: Infectious Diseases Authors: Fernando R, Capone D, Elrich S, Mantovani R, Quarles L, D'Amato A, Lowe N, Malhotra A, Khoo T, Zufan S, Morales-Betoulle M, Brown SM, Cannon D, Graziano JC, Klena JD, Whitmer S, Nichol ST, Strachan P, Camins BC, Marcos LA Tags: Emerg Infect Dis Source Type: research

Scrub Typhus in Continental Chile, 2016-20181.
We report a series of cases, acquired over a wide geographical range in continental Chile during 2016-2018, demonstrating that this emerging rickettsial infection is also found on the mainland of South America. PMID: 30835200 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - March 6, 2019 Category: Infectious Diseases Authors: Weitzel T, Martínez-Valdebenito C, Acosta-Jamett G, Jiang J, Richards AL, Abarca K Tags: Emerg Infect Dis Source Type: research

Increase in Lassa Fever Cases in Nigeria, January-March 2018.
Abstract We reviewed data pertaining to the massive wave of Lassa fever cases that occurred in Nigeria in 2018. No new virus strains were detected, but in 2018, the outbreak response was intensified, additional diagnostic support was available, and surveillance sensitivity increased. These factors probably contributed to the high case count. PMID: 30807268 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - February 27, 2019 Category: Infectious Diseases Authors: Ilori EA, Frank C, Dan-Nwafor CC, Ipadeola O, Krings A, Ukponu W, Womi-Eteng OE, Adeyemo A, Mutbam SK, Musa EO, Lasuba CLP, Alemu W, Okogbenin S, Ogbaini E, Unigwe U, Ogah E, Onoh R, Abejegah C, Ayodeji O, Ihekweazu C Tags: Emerg Infect Dis Source Type: research

Infectious Dose of African Swine Fever Virus When Consumed Naturally in Liquid or Feed.
Abstract African swine fever virus (ASFV) is a contagious, rapidly spreading, transboundary animal disease and a major threat to pork production globally. Although plant-based feed has been identified as a potential route for virus introduction onto swine farms, little is known about the risks for ASFV transmission in feed. We aimed to determine the minimum and median infectious doses of the Georgia 2007 strain of ASFV through oral exposure during natural drinking and feeding behaviors. The minimum infectious dose of ASFV in liquid was 100 50% tissue culture infectious dose (TCID50), compared with 104 TCID50 in fe...
Source: Emerging Infectious Diseases - February 16, 2019 Category: Infectious Diseases Authors: Niederwerder MC, Stoian AMM, Rowland RRR, Dritz SS, Petrovan V, Constance LA, Gebhardt JT, Olcha M, Jones CK, Woodworth JC, Fang Y, Liang J, Hefley TJ Tags: Emerg Infect Dis Source Type: research

Need for Aeromedical Evacuation High-Level Containment Transport Guidelines.
Abstract Circumstances exist that call for the aeromedical evacuation high-level containment transport (AE-HLCT) of patients with highly hazardous communicable diseases. A small number of organizations maintain AE-HLCT capabilities, and little is publicly available regarding the practices. The time is ripe for the development of standards and consensus guidelines involving AE-HLCT. PMID: 30741629 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - February 13, 2019 Category: Infectious Diseases Authors: Gibbs SG, Herstein JJ, Le AB, Beam EL, Cieslak TJ, Lawler JV, Santarpia JL, Stentz TL, Kopocis-Herstein KR, Achutan C, Carter GW, Lowe JJ Tags: Emerg Infect Dis Source Type: research