Ehrlichiosis Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

The geographic limits and life history of the tropical brown dog tick, Rhipicephalus linnaei (Audouin, 1826), in Australia with notes on the spread of Ehrlichia canis
Int J Parasitol. 2024 Apr 10:S0020-7519(24)00074-2. doi: 10.1016/j.ijpara.2024.04.004. Online ahead of print.ABSTRACTThe tropical brown dog tick, Rhipicephalus linnaei, is a tick of much medical, veterinary, and zoonotic importance. This tick has a nearly world-wide distribution due to its ability to survive and propagate in kennels and houses. Rhipicephalus linnaei is the vector of Ehrlichia canis, the causative agent of canine monocytic ehrlichiosis, an often debilitating disease of canids and, occasionally, humans. To prevent incursion of E. canis into Australia, dogs entering Australia have been required to have a nega...
Source: International Journal for Parasitology - April 12, 2024 Category: Parasitology Authors: Ernest J M Teo Kimberly L Evasco Dayana Barker M L Levin Stephen C Barker Source Type: research

Assessment of the effect of long-term serum storage for retrospective serologic diagnosis of canine monocytic ehrlichiosis (Ehrlichia canis)
Comp Immunol Microbiol Infect Dis. 2024 Apr 2;108:102170. doi: 10.1016/j.cimid.2024.102170. Online ahead of print.ABSTRACTThere is currently sparse information on the possible effect of long-term storage of serum specimens for the retrospective serodiagnosis of canine monocytic ehrlichiosis (CME). The aim of this study was to assess the agreement between the original serologic outcome and the results of a repeat indirect fluorescent antibody (IFA) assay for the detection of IgG antibodies against E. canis. A secondary aim was to compare the diagnostic performance of two commercially available point-of-care (POC) immunochro...
Source: Comparative immunology, microbiology and infectious diseases. - April 6, 2024 Category: Allergy & Immunology Authors: Melina Karagkouni Katerina Spilioti Eleftherios Meletis Polychronis Kostoulas Christos Koutinas Konstantina Theodorou Edward B Breitschwerdt Mathios E Mylonakis Source Type: research

Tick-Borne Illnesses in Emergency and Wilderness Medicine
This review highlights the causative organisms, clinical features, diagnosis, and treatment of the most common tick-borne illnesses in the United States, including Lyme disease, Rocky Mountain spotted fever, anaplasmosis, ehrlichiosis, tularemia, Powassan virus, and alpha-gal syndrome. Tick bite prevention strategies and some basic tick removal recommendations are also provided. (Source: Emergency Medicine Clinics of North America)
Source: Emergency Medicine Clinics of North America - March 21, 2024 Category: Emergency Medicine Authors: Michael D. Sullivan, Kyle Glose, Douglas Sward Source Type: research

High prevalence of asymptomatic Anaplasma spp. infection in school-aged children in southeastern Gabon
The members of the Anaplasmataceae family are obligate intracellular Gram-negative bacteria with veterinary and public health importance [1]. The genera Anaplasma and Ehrlichia include species that cause anaplasmosis and ehrlichiosis, respectively, in humans and animals. Emerging infections with new Ehrlichia and Anaplasma species have become more frequently diagnosed as the cause of human infections, as animal reservoirs and tick vectors have increased in numbers and humans have inhabited areas where reservoir and tick populations are high [1]. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - December 6, 2023 Category: Infectious Diseases Authors: Nal Kennedy Ndjangangoye, Patrice Makouloutou Nzassi, F élicien Bangueboussa, Chérone Nancy Mbani Mpega Ntigui, Lady Charlene Kouna, Nancy Diamella Moukodoum, Nick Chenis Atiga, Alain Prince Okouga, Steede Seinnat Ontoua, Jean-Bernard Lekana-Douki, Sand Tags: Short Communication Source Type: research

Hepatocyte-specific regulation of autophagy and inflammasome activation via MyD88 during lethal Ehrlichia infection
In conclusion, this study demonstrates that hepatocyte-specific regulation of autophagy and inflammasome pathway via MyD88 is distinct than MyD88 signaling in macrophages during fatal ehrlichiosis. Understanding hepatocyte-specific signaling is critical for the development of new therapeutics against liver-targeting pathogens such as Ehrlichia. (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - November 7, 2023 Category: Allergy & Immunology Source Type: research

Phylogenetic analysis of Ehrlichia species isolated from horses and dogs in Iran
This study aimed to determine the prevalence and phylogenetic analysis of Ehrlichia spp. in horses and dogs in Iran. Blood samples were collected from 400 animals, including 200 horses and 200 dogs, from five different provinces in Iran. Polymerase chain reaction (PCR) was used to detect Ehrlichia spp. based on amplification of the 16S rRNA gene. The semi-nested PCR method was used to amplify the dsb, TRP36, and gltA genes. The results showed that 4.5 % of the samples (3 % horses and 6 % dogs) were positive for Ehrlichia sp. The highest prevalence was observed in Kerman and Khuzestan, while the lowest was found in West Aze...
Source: Comparative immunology, microbiology and infectious diseases. - November 1, 2023 Category: Allergy & Immunology Authors: Siamak Molazadeh Amir Tukmechi Mojtaba Hadian Bahram Dalir-Naghadeh Source Type: research

Canine ehrlichiosis seropositivity and associated factors in Kenya and Tanzania: a retrospective study
This study determin... (Source: BMC Veterinary Research)
Source: BMC Veterinary Research - September 28, 2023 Category: Veterinary Research Authors: Laboso Judy, Kihurani David, Kimeli Peter and Shah Dhaval Tags: Research Source Type: research

Correction for Zhi et al., “Cloning and Expression of the 44-Kilodalton Major Outer Membrane Protein Gene of the Human Granulocytic Ehrlichiosis Agent and Application of the Recombinant Protein to Serodiagnosis”
Journal of Clinical Microbiology, Ahead of Print. (Source: Journal of Clinical Microbiology)
Source: Journal of Clinical Microbiology - September 7, 2023 Category: Microbiology Authors: N. Zhi N. Ohashi Y. Rikihisa H. W. Horowitz G. P. Wormser K. Hechemy Source Type: research

Multiple Ehrlichia chaffeensis genes critical for persistent infection in a vertebrate host are identified as nonessential for its growth in the tick vector; Amblyomma americanum
This study documents novel vector- and host-specific differences in E. chaffeensis for its functional gene requirements. (Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - June 27, 2023 Category: Microbiology Source Type: research

RPA/CRISPR-cas12a as a specific, sensitive and rapid method for diagnosing Ehrlichia canis and Anaplasma platys in dogs in Thailand
In this study, a recombinase polymerase amplification (RPA) coupled with CRISPR-Cas12a methods was established to detectE. canis andA. platys infection in dogs based on the 16S rRNA. The optimal condition for DNA amplification by RPA was 37 °C for 20 min, followed by CRISPR-Cas12a digestion at 37 °C for one hour. A combination of RPA and the cas12a detection method did not react with other pathogens and demonstrated strong sensitivity, detecting as low as 100 copies of bothE. canis andA. platys. This simultaneous detection method was significantly more sensitive than conventional PCR. The RPA-assisted cas12a assay pr...
Source: Veterinary Research Communications - March 30, 2023 Category: Veterinary Research Source Type: research