Safety issues of raw milk: evaluation of bacteriological and physicochemical characteristics of human milk from a bank in a teaching hospital, focusing on Staphylococcus species
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e54. doi: 10.1590/S1678-9946202163054. eCollection 2021.ABSTRACTMany infants are nurtured with milk supplied by human banks, whose bacteriological and physical-chemical profiles are a major issue. We investigated the bacteriological and physical-chemical characteristics, as well as genotypic and phenotypic and profiles of Staphylococcus species isolated from 240 samples of breast milk from a bank in a teaching hospital. Dornic acidity of milk revealed that 95.4% (229/240) had acceptable limits (
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Tatiana Salerno Amanda Keller Siqueira Jos é Paes de Almeida Nogueira Pinto Maria de Lourdes Ribeiro de Souza da Cunha Patr ícia Kelly Silvestre Larissa Anuska Zeni Condas Gustavo Henrique Batista Lara Juliano Gon çalves Pereira Aristeu Vieira da Silva Source Type: research

Association of TAP1 1177A & gt;G and 2090A & gt;G gene polymorphisms with latent tuberculosis infections in sheltered populations, in the metropolitan area of Guadalajara, Mexico: a pilot study
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e55. doi: 10.1590/S1678-9946202163055. eCollection 2021.ABSTRACTLatent tuberculosis infection (LTBI) is a condition that has no clinical signs and symptoms. LTBI patients are characterized by persistent immune responses to Mycobacterium tuberculosis, and approximately 5-10% of these infected individuals will develop active TB at some point in their lives. The antigen transporter associated with antigen processing (TAP1) is a protein involved in the transport of the antigen from the cytoplasm to the endoplasmic reticulum by means of the association with MHC class I molecules. It pl...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Gerardo Cazarez-Navarro Jaime Palomares-Mar ín Sergio Yair Rodr íguez-Preciado Ana Laura Pereira-Su árez Erika Mart ínez-López Eva Adriana Bacilio-Medrano Selene Huerta-Olvera Iv án Isidro Hernández-Cañaveral Source Type: research

Basic knowledge about visceral leishmaniasis before and after educational intervention among primary health care professionals in Midwestern Brazil
This study assessed the impact of an educational intervention on the basic knowledge about visceral leishmaniasis (VL) among PHC professionals from the Brazilian municipality of Rondonopolis, an important endemic area for VL. Responses provided by physicians, nurses, nursing technicians and community health agents from 12 PHC facilities were recorded through the application of self-completed and semi-structured questionnaires before (n=92) and after (n=64) an in-person health training course covering various aspects of VL. Closed- and open-ended responses were compared by the chi-square test and analyses of word clouds, re...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Amanda Gabriela de Carvalho Isaac Alves Larissa Marquiori Borges Laura Bordignon Spessatto Ludiele Souza Castro Jo ão Gabriel Guimarães Luz Source Type: research

Cost-effectiveness analysis and budgetary impact of the Cryptococcal Antigen Lateral Flow Assay (CRAG-LFA) implementation for the screening and diagnosis of cryptococcosis in asymptomatic people living with HIV in Brazil
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e57. doi: 10.1590/S1678-9946202163057. eCollection 2021.ABSTRACTCryptococcal infection is a frequent cause of mortality in Brazilian HIV-infected patients. The present study aimed to evaluate the cost-effectiveness and budgetary impact of four cryptococcosis screening strategies in HIV-infected patients with CD4+ ≤ 200 cells/mm3, in Brazil. A Monte Carlo microsimulation was used to compare the following diagnostic tests: a systematic serum cryptococcal antigen (CRAG) screening with latex agglutination (CRAG-LA), a lateral flow immunochromatographic test (CRAG-LFA), India ink st...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Cid Manso de Mello Vianna Gabriela Bittencourt Gonzalez Mosegui Source Type: research

Early detection of SARS-CoV-2 P.1 variant in Southern Brazil and reinfection of the same patient by P.2
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e58. doi: 10.1590/S1678-9946202163058. eCollection 2021.ABSTRACTMultiple variants of the Severe Acute Respiratory Syndrome coronavirus 2 virus (SARS-CoV-2) have been constantly reported across the world. The B.1.1.28 lineage has been evolving in Brazil since February 2020 and originated the P.1 variant of concern (VOC), recently named as the Gamma variant by the newly WHO nomenclature proposal, and P.2 as a variant of interest (VOI). Here we describe an early case of P.1 primary infection in Southern Brazil in late November 2020, soon after the emergence of the variant in Manaus, ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Mariana Soares da Silva Meriane Demoliner Alana Witt Hansen Juliana Schons Gularte Fl ávio Silveira F ágner Henrique Heldt Micheli Filippi Vyctoria Malayhka de Abreu G óes Pereira Francini Pereira da Silva Larissa Mallmann Pietra Fink Luana Let ícia d Source Type: research

Safety issues of raw milk: evaluation of bacteriological and physicochemical characteristics of human milk from a bank in a teaching hospital, focusing on Staphylococcus species
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e54. doi: 10.1590/S1678-9946202163054. eCollection 2021.ABSTRACTMany infants are nurtured with milk supplied by human banks, whose bacteriological and physical-chemical profiles are a major issue. We investigated the bacteriological and physical-chemical characteristics, as well as genotypic and phenotypic and profiles of Staphylococcus species isolated from 240 samples of breast milk from a bank in a teaching hospital. Dornic acidity of milk revealed that 95.4% (229/240) had acceptable limits (
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Tatiana Salerno Amanda Keller Siqueira Jos é Paes de Almeida Nogueira Pinto Maria de Lourdes Ribeiro de Souza da Cunha Patr ícia Kelly Silvestre Larissa Anuska Zeni Condas Gustavo Henrique Batista Lara Juliano Gon çalves Pereira Aristeu Vieira da Silva Source Type: research

Association of TAP1 1177A & gt;G and 2090A & gt;G gene polymorphisms with latent tuberculosis infections in sheltered populations, in the metropolitan area of Guadalajara, Mexico: a pilot study
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e55. doi: 10.1590/S1678-9946202163055. eCollection 2021.ABSTRACTLatent tuberculosis infection (LTBI) is a condition that has no clinical signs and symptoms. LTBI patients are characterized by persistent immune responses to Mycobacterium tuberculosis, and approximately 5-10% of these infected individuals will develop active TB at some point in their lives. The antigen transporter associated with antigen processing (TAP1) is a protein involved in the transport of the antigen from the cytoplasm to the endoplasmic reticulum by means of the association with MHC class I molecules. It pl...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Gerardo Cazarez-Navarro Jaime Palomares-Mar ín Sergio Yair Rodr íguez-Preciado Ana Laura Pereira-Su árez Erika Mart ínez-López Eva Adriana Bacilio-Medrano Selene Huerta-Olvera Iv án Isidro Hernández-Cañaveral Source Type: research

Basic knowledge about visceral leishmaniasis before and after educational intervention among primary health care professionals in Midwestern Brazil
This study assessed the impact of an educational intervention on the basic knowledge about visceral leishmaniasis (VL) among PHC professionals from the Brazilian municipality of Rondonopolis, an important endemic area for VL. Responses provided by physicians, nurses, nursing technicians and community health agents from 12 PHC facilities were recorded through the application of self-completed and semi-structured questionnaires before (n=92) and after (n=64) an in-person health training course covering various aspects of VL. Closed- and open-ended responses were compared by the chi-square test and analyses of word clouds, re...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Amanda Gabriela de Carvalho Isaac Alves Larissa Marquiori Borges Laura Bordignon Spessatto Ludiele Souza Castro Jo ão Gabriel Guimarães Luz Source Type: research

Cost-effectiveness analysis and budgetary impact of the Cryptococcal Antigen Lateral Flow Assay (CRAG-LFA) implementation for the screening and diagnosis of cryptococcosis in asymptomatic people living with HIV in Brazil
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e57. doi: 10.1590/S1678-9946202163057. eCollection 2021.ABSTRACTCryptococcal infection is a frequent cause of mortality in Brazilian HIV-infected patients. The present study aimed to evaluate the cost-effectiveness and budgetary impact of four cryptococcosis screening strategies in HIV-infected patients with CD4+ ≤ 200 cells/mm3, in Brazil. A Monte Carlo microsimulation was used to compare the following diagnostic tests: a systematic serum cryptococcal antigen (CRAG) screening with latex agglutination (CRAG-LA), a lateral flow immunochromatographic test (CRAG-LFA), India ink st...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Cid Manso de Mello Vianna Gabriela Bittencourt Gonzalez Mosegui Source Type: research

Early detection of SARS-CoV-2 P.1 variant in Southern Brazil and reinfection of the same patient by P.2
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e58. doi: 10.1590/S1678-9946202163058. eCollection 2021.ABSTRACTMultiple variants of the Severe Acute Respiratory Syndrome coronavirus 2 virus (SARS-CoV-2) have been constantly reported across the world. The B.1.1.28 lineage has been evolving in Brazil since February 2020 and originated the P.1 variant of concern (VOC), recently named as the Gamma variant by the newly WHO nomenclature proposal, and P.2 as a variant of interest (VOI). Here we describe an early case of P.1 primary infection in Southern Brazil in late November 2020, soon after the emergence of the variant in Manaus, ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Mariana Soares da Silva Meriane Demoliner Alana Witt Hansen Juliana Schons Gularte Fl ávio Silveira F ágner Henrique Heldt Micheli Filippi Vyctoria Malayhka de Abreu G óes Pereira Francini Pereira da Silva Larissa Mallmann Pietra Fink Luana Let ícia d Source Type: research

Safety issues of raw milk: evaluation of bacteriological and physicochemical characteristics of human milk from a bank in a teaching hospital, focusing on Staphylococcus species
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e54. doi: 10.1590/S1678-9946202163054. eCollection 2021.ABSTRACTMany infants are nurtured with milk supplied by human banks, whose bacteriological and physical-chemical profiles are a major issue. We investigated the bacteriological and physical-chemical characteristics, as well as genotypic and phenotypic and profiles of Staphylococcus species isolated from 240 samples of breast milk from a bank in a teaching hospital. Dornic acidity of milk revealed that 95.4% (229/240) had acceptable limits (
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Tatiana Salerno Amanda Keller Siqueira Jos é Paes de Almeida Nogueira Pinto Maria de Lourdes Ribeiro de Souza da Cunha Patr ícia Kelly Silvestre Larissa Anuska Zeni Condas Gustavo Henrique Batista Lara Juliano Gon çalves Pereira Aristeu Vieira da Silva Source Type: research

Association of TAP1 1177A & gt;G and 2090A & gt;G gene polymorphisms with latent tuberculosis infections in sheltered populations, in the metropolitan area of Guadalajara, Mexico: a pilot study
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e55. doi: 10.1590/S1678-9946202163055. eCollection 2021.ABSTRACTLatent tuberculosis infection (LTBI) is a condition that has no clinical signs and symptoms. LTBI patients are characterized by persistent immune responses to Mycobacterium tuberculosis, and approximately 5-10% of these infected individuals will develop active TB at some point in their lives. The antigen transporter associated with antigen processing (TAP1) is a protein involved in the transport of the antigen from the cytoplasm to the endoplasmic reticulum by means of the association with MHC class I molecules. It pl...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Gerardo Cazarez-Navarro Jaime Palomares-Mar ín Sergio Yair Rodr íguez-Preciado Ana Laura Pereira-Su árez Erika Mart ínez-López Eva Adriana Bacilio-Medrano Selene Huerta-Olvera Iv án Isidro Hernández-Cañaveral Source Type: research

Basic knowledge about visceral leishmaniasis before and after educational intervention among primary health care professionals in Midwestern Brazil
This study assessed the impact of an educational intervention on the basic knowledge about visceral leishmaniasis (VL) among PHC professionals from the Brazilian municipality of Rondonopolis, an important endemic area for VL. Responses provided by physicians, nurses, nursing technicians and community health agents from 12 PHC facilities were recorded through the application of self-completed and semi-structured questionnaires before (n=92) and after (n=64) an in-person health training course covering various aspects of VL. Closed- and open-ended responses were compared by the chi-square test and analyses of word clouds, re...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Amanda Gabriela de Carvalho Isaac Alves Larissa Marquiori Borges Laura Bordignon Spessatto Ludiele Souza Castro Jo ão Gabriel Guimarães Luz Source Type: research

Cost-effectiveness analysis and budgetary impact of the Cryptococcal Antigen Lateral Flow Assay (CRAG-LFA) implementation for the screening and diagnosis of cryptococcosis in asymptomatic people living with HIV in Brazil
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e57. doi: 10.1590/S1678-9946202163057. eCollection 2021.ABSTRACTCryptococcal infection is a frequent cause of mortality in Brazilian HIV-infected patients. The present study aimed to evaluate the cost-effectiveness and budgetary impact of four cryptococcosis screening strategies in HIV-infected patients with CD4+ ≤ 200 cells/mm3, in Brazil. A Monte Carlo microsimulation was used to compare the following diagnostic tests: a systematic serum cryptococcal antigen (CRAG) screening with latex agglutination (CRAG-LA), a lateral flow immunochromatographic test (CRAG-LFA), India ink st...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Cid Manso de Mello Vianna Gabriela Bittencourt Gonzalez Mosegui Source Type: research

Early detection of SARS-CoV-2 P.1 variant in Southern Brazil and reinfection of the same patient by P.2
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e58. doi: 10.1590/S1678-9946202163058. eCollection 2021.ABSTRACTMultiple variants of the Severe Acute Respiratory Syndrome coronavirus 2 virus (SARS-CoV-2) have been constantly reported across the world. The B.1.1.28 lineage has been evolving in Brazil since February 2020 and originated the P.1 variant of concern (VOC), recently named as the Gamma variant by the newly WHO nomenclature proposal, and P.2 as a variant of interest (VOI). Here we describe an early case of P.1 primary infection in Southern Brazil in late November 2020, soon after the emergence of the variant in Manaus, ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Mariana Soares da Silva Meriane Demoliner Alana Witt Hansen Juliana Schons Gularte Fl ávio Silveira F ágner Henrique Heldt Micheli Filippi Vyctoria Malayhka de Abreu G óes Pereira Francini Pereira da Silva Larissa Mallmann Pietra Fink Luana Let ícia d Source Type: research

Safety issues of raw milk: evaluation of bacteriological and physicochemical characteristics of human milk from a bank in a teaching hospital, focusing on Staphylococcus species
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e54. doi: 10.1590/S1678-9946202163054. eCollection 2021.ABSTRACTMany infants are nurtured with milk supplied by human banks, whose bacteriological and physical-chemical profiles are a major issue. We investigated the bacteriological and physical-chemical characteristics, as well as genotypic and phenotypic and profiles of Staphylococcus species isolated from 240 samples of breast milk from a bank in a teaching hospital. Dornic acidity of milk revealed that 95.4% (229/240) had acceptable limits (
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Tatiana Salerno Amanda Keller Siqueira Jos é Paes de Almeida Nogueira Pinto Maria de Lourdes Ribeiro de Souza da Cunha Patr ícia Kelly Silvestre Larissa Anuska Zeni Condas Gustavo Henrique Batista Lara Juliano Gon çalves Pereira Aristeu Vieira da Silva Source Type: research

Association of TAP1 1177A & gt;G and 2090A & gt;G gene polymorphisms with latent tuberculosis infections in sheltered populations, in the metropolitan area of Guadalajara, Mexico: a pilot study
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e55. doi: 10.1590/S1678-9946202163055. eCollection 2021.ABSTRACTLatent tuberculosis infection (LTBI) is a condition that has no clinical signs and symptoms. LTBI patients are characterized by persistent immune responses to Mycobacterium tuberculosis, and approximately 5-10% of these infected individuals will develop active TB at some point in their lives. The antigen transporter associated with antigen processing (TAP1) is a protein involved in the transport of the antigen from the cytoplasm to the endoplasmic reticulum by means of the association with MHC class I molecules. It pl...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Gerardo Cazarez-Navarro Jaime Palomares-Mar ín Sergio Yair Rodr íguez-Preciado Ana Laura Pereira-Su árez Erika Mart ínez-López Eva Adriana Bacilio-Medrano Selene Huerta-Olvera Iv án Isidro Hernández-Cañaveral Source Type: research

Basic knowledge about visceral leishmaniasis before and after educational intervention among primary health care professionals in Midwestern Brazil
This study assessed the impact of an educational intervention on the basic knowledge about visceral leishmaniasis (VL) among PHC professionals from the Brazilian municipality of Rondonopolis, an important endemic area for VL. Responses provided by physicians, nurses, nursing technicians and community health agents from 12 PHC facilities were recorded through the application of self-completed and semi-structured questionnaires before (n=92) and after (n=64) an in-person health training course covering various aspects of VL. Closed- and open-ended responses were compared by the chi-square test and analyses of word clouds, re...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Amanda Gabriela de Carvalho Isaac Alves Larissa Marquiori Borges Laura Bordignon Spessatto Ludiele Souza Castro Jo ão Gabriel Guimarães Luz Source Type: research

Cost-effectiveness analysis and budgetary impact of the Cryptococcal Antigen Lateral Flow Assay (CRAG-LFA) implementation for the screening and diagnosis of cryptococcosis in asymptomatic people living with HIV in Brazil
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e57. doi: 10.1590/S1678-9946202163057. eCollection 2021.ABSTRACTCryptococcal infection is a frequent cause of mortality in Brazilian HIV-infected patients. The present study aimed to evaluate the cost-effectiveness and budgetary impact of four cryptococcosis screening strategies in HIV-infected patients with CD4+ ≤ 200 cells/mm3, in Brazil. A Monte Carlo microsimulation was used to compare the following diagnostic tests: a systematic serum cryptococcal antigen (CRAG) screening with latex agglutination (CRAG-LA), a lateral flow immunochromatographic test (CRAG-LFA), India ink st...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Cid Manso de Mello Vianna Gabriela Bittencourt Gonzalez Mosegui Source Type: research

Early detection of SARS-CoV-2 P.1 variant in Southern Brazil and reinfection of the same patient by P.2
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e58. doi: 10.1590/S1678-9946202163058. eCollection 2021.ABSTRACTMultiple variants of the Severe Acute Respiratory Syndrome coronavirus 2 virus (SARS-CoV-2) have been constantly reported across the world. The B.1.1.28 lineage has been evolving in Brazil since February 2020 and originated the P.1 variant of concern (VOC), recently named as the Gamma variant by the newly WHO nomenclature proposal, and P.2 as a variant of interest (VOI). Here we describe an early case of P.1 primary infection in Southern Brazil in late November 2020, soon after the emergence of the variant in Manaus, ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Mariana Soares da Silva Meriane Demoliner Alana Witt Hansen Juliana Schons Gularte Fl ávio Silveira F ágner Henrique Heldt Micheli Filippi Vyctoria Malayhka de Abreu G óes Pereira Francini Pereira da Silva Larissa Mallmann Pietra Fink Luana Let ícia d Source Type: research

Safety issues of raw milk: evaluation of bacteriological and physicochemical characteristics of human milk from a bank in a teaching hospital, focusing on Staphylococcus species
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e54. doi: 10.1590/S1678-9946202163054. eCollection 2021.ABSTRACTMany infants are nurtured with milk supplied by human banks, whose bacteriological and physical-chemical profiles are a major issue. We investigated the bacteriological and physical-chemical characteristics, as well as genotypic and phenotypic and profiles of Staphylococcus species isolated from 240 samples of breast milk from a bank in a teaching hospital. Dornic acidity of milk revealed that 95.4% (229/240) had acceptable limits (
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Tatiana Salerno Amanda Keller Siqueira Jos é Paes de Almeida Nogueira Pinto Maria de Lourdes Ribeiro de Souza da Cunha Patr ícia Kelly Silvestre Larissa Anuska Zeni Condas Gustavo Henrique Batista Lara Juliano Gon çalves Pereira Aristeu Vieira da Silva Source Type: research

Association of TAP1 1177A & gt;G and 2090A & gt;G gene polymorphisms with latent tuberculosis infections in sheltered populations, in the metropolitan area of Guadalajara, Mexico: a pilot study
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e55. doi: 10.1590/S1678-9946202163055. eCollection 2021.ABSTRACTLatent tuberculosis infection (LTBI) is a condition that has no clinical signs and symptoms. LTBI patients are characterized by persistent immune responses to Mycobacterium tuberculosis, and approximately 5-10% of these infected individuals will develop active TB at some point in their lives. The antigen transporter associated with antigen processing (TAP1) is a protein involved in the transport of the antigen from the cytoplasm to the endoplasmic reticulum by means of the association with MHC class I molecules. It pl...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Gerardo Cazarez-Navarro Jaime Palomares-Mar ín Sergio Yair Rodr íguez-Preciado Ana Laura Pereira-Su árez Erika Mart ínez-López Eva Adriana Bacilio-Medrano Selene Huerta-Olvera Iv án Isidro Hernández-Cañaveral Source Type: research

Basic knowledge about visceral leishmaniasis before and after educational intervention among primary health care professionals in Midwestern Brazil
This study assessed the impact of an educational intervention on the basic knowledge about visceral leishmaniasis (VL) among PHC professionals from the Brazilian municipality of Rondonopolis, an important endemic area for VL. Responses provided by physicians, nurses, nursing technicians and community health agents from 12 PHC facilities were recorded through the application of self-completed and semi-structured questionnaires before (n=92) and after (n=64) an in-person health training course covering various aspects of VL. Closed- and open-ended responses were compared by the chi-square test and analyses of word clouds, re...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Amanda Gabriela de Carvalho Isaac Alves Larissa Marquiori Borges Laura Bordignon Spessatto Ludiele Souza Castro Jo ão Gabriel Guimarães Luz Source Type: research

Cost-effectiveness analysis and budgetary impact of the Cryptococcal Antigen Lateral Flow Assay (CRAG-LFA) implementation for the screening and diagnosis of cryptococcosis in asymptomatic people living with HIV in Brazil
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e57. doi: 10.1590/S1678-9946202163057. eCollection 2021.ABSTRACTCryptococcal infection is a frequent cause of mortality in Brazilian HIV-infected patients. The present study aimed to evaluate the cost-effectiveness and budgetary impact of four cryptococcosis screening strategies in HIV-infected patients with CD4+ ≤ 200 cells/mm3, in Brazil. A Monte Carlo microsimulation was used to compare the following diagnostic tests: a systematic serum cryptococcal antigen (CRAG) screening with latex agglutination (CRAG-LA), a lateral flow immunochromatographic test (CRAG-LFA), India ink st...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Cid Manso de Mello Vianna Gabriela Bittencourt Gonzalez Mosegui Source Type: research

Early detection of SARS-CoV-2 P.1 variant in Southern Brazil and reinfection of the same patient by P.2
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e58. doi: 10.1590/S1678-9946202163058. eCollection 2021.ABSTRACTMultiple variants of the Severe Acute Respiratory Syndrome coronavirus 2 virus (SARS-CoV-2) have been constantly reported across the world. The B.1.1.28 lineage has been evolving in Brazil since February 2020 and originated the P.1 variant of concern (VOC), recently named as the Gamma variant by the newly WHO nomenclature proposal, and P.2 as a variant of interest (VOI). Here we describe an early case of P.1 primary infection in Southern Brazil in late November 2020, soon after the emergence of the variant in Manaus, ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Mariana Soares da Silva Meriane Demoliner Alana Witt Hansen Juliana Schons Gularte Fl ávio Silveira F ágner Henrique Heldt Micheli Filippi Vyctoria Malayhka de Abreu G óes Pereira Francini Pereira da Silva Larissa Mallmann Pietra Fink Luana Let ícia d Source Type: research

Safety issues of raw milk: evaluation of bacteriological and physicochemical characteristics of human milk from a bank in a teaching hospital, focusing on Staphylococcus species
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e54. doi: 10.1590/S1678-9946202163054. eCollection 2021.ABSTRACTMany infants are nurtured with milk supplied by human banks, whose bacteriological and physical-chemical profiles are a major issue. We investigated the bacteriological and physical-chemical characteristics, as well as genotypic and phenotypic and profiles of Staphylococcus species isolated from 240 samples of breast milk from a bank in a teaching hospital. Dornic acidity of milk revealed that 95.4% (229/240) had acceptable limits (
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Tatiana Salerno Amanda Keller Siqueira Jos é Paes de Almeida Nogueira Pinto Maria de Lourdes Ribeiro de Souza da Cunha Patr ícia Kelly Silvestre Larissa Anuska Zeni Condas Gustavo Henrique Batista Lara Juliano Gon çalves Pereira Aristeu Vieira da Silva Source Type: research

Association of TAP1 1177A & gt;G and 2090A & gt;G gene polymorphisms with latent tuberculosis infections in sheltered populations, in the metropolitan area of Guadalajara, Mexico: a pilot study
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e55. doi: 10.1590/S1678-9946202163055. eCollection 2021.ABSTRACTLatent tuberculosis infection (LTBI) is a condition that has no clinical signs and symptoms. LTBI patients are characterized by persistent immune responses to Mycobacterium tuberculosis, and approximately 5-10% of these infected individuals will develop active TB at some point in their lives. The antigen transporter associated with antigen processing (TAP1) is a protein involved in the transport of the antigen from the cytoplasm to the endoplasmic reticulum by means of the association with MHC class I molecules. It pl...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Gerardo Cazarez-Navarro Jaime Palomares-Mar ín Sergio Yair Rodr íguez-Preciado Ana Laura Pereira-Su árez Erika Mart ínez-López Eva Adriana Bacilio-Medrano Selene Huerta-Olvera Iv án Isidro Hernández-Cañaveral Source Type: research

Basic knowledge about visceral leishmaniasis before and after educational intervention among primary health care professionals in Midwestern Brazil
This study assessed the impact of an educational intervention on the basic knowledge about visceral leishmaniasis (VL) among PHC professionals from the Brazilian municipality of Rondonopolis, an important endemic area for VL. Responses provided by physicians, nurses, nursing technicians and community health agents from 12 PHC facilities were recorded through the application of self-completed and semi-structured questionnaires before (n=92) and after (n=64) an in-person health training course covering various aspects of VL. Closed- and open-ended responses were compared by the chi-square test and analyses of word clouds, re...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Amanda Gabriela de Carvalho Isaac Alves Larissa Marquiori Borges Laura Bordignon Spessatto Ludiele Souza Castro Jo ão Gabriel Guimarães Luz Source Type: research

Cost-effectiveness analysis and budgetary impact of the Cryptococcal Antigen Lateral Flow Assay (CRAG-LFA) implementation for the screening and diagnosis of cryptococcosis in asymptomatic people living with HIV in Brazil
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e57. doi: 10.1590/S1678-9946202163057. eCollection 2021.ABSTRACTCryptococcal infection is a frequent cause of mortality in Brazilian HIV-infected patients. The present study aimed to evaluate the cost-effectiveness and budgetary impact of four cryptococcosis screening strategies in HIV-infected patients with CD4+ ≤ 200 cells/mm3, in Brazil. A Monte Carlo microsimulation was used to compare the following diagnostic tests: a systematic serum cryptococcal antigen (CRAG) screening with latex agglutination (CRAG-LA), a lateral flow immunochromatographic test (CRAG-LFA), India ink st...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Cid Manso de Mello Vianna Gabriela Bittencourt Gonzalez Mosegui Source Type: research

Early detection of SARS-CoV-2 P.1 variant in Southern Brazil and reinfection of the same patient by P.2
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e58. doi: 10.1590/S1678-9946202163058. eCollection 2021.ABSTRACTMultiple variants of the Severe Acute Respiratory Syndrome coronavirus 2 virus (SARS-CoV-2) have been constantly reported across the world. The B.1.1.28 lineage has been evolving in Brazil since February 2020 and originated the P.1 variant of concern (VOC), recently named as the Gamma variant by the newly WHO nomenclature proposal, and P.2 as a variant of interest (VOI). Here we describe an early case of P.1 primary infection in Southern Brazil in late November 2020, soon after the emergence of the variant in Manaus, ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Mariana Soares da Silva Meriane Demoliner Alana Witt Hansen Juliana Schons Gularte Fl ávio Silveira F ágner Henrique Heldt Micheli Filippi Vyctoria Malayhka de Abreu G óes Pereira Francini Pereira da Silva Larissa Mallmann Pietra Fink Luana Let ícia d Source Type: research

Safety issues of raw milk: evaluation of bacteriological and physicochemical characteristics of human milk from a bank in a teaching hospital, focusing on Staphylococcus species
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e54. doi: 10.1590/S1678-9946202163054. eCollection 2021.ABSTRACTMany infants are nurtured with milk supplied by human banks, whose bacteriological and physical-chemical profiles are a major issue. We investigated the bacteriological and physical-chemical characteristics, as well as genotypic and phenotypic and profiles of Staphylococcus species isolated from 240 samples of breast milk from a bank in a teaching hospital. Dornic acidity of milk revealed that 95.4% (229/240) had acceptable limits (
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Tatiana Salerno Amanda Keller Siqueira Jos é Paes de Almeida Nogueira Pinto Maria de Lourdes Ribeiro de Souza da Cunha Patr ícia Kelly Silvestre Larissa Anuska Zeni Condas Gustavo Henrique Batista Lara Juliano Gon çalves Pereira Aristeu Vieira da Silva Source Type: research

Association of TAP1 1177A & gt;G and 2090A & gt;G gene polymorphisms with latent tuberculosis infections in sheltered populations, in the metropolitan area of Guadalajara, Mexico: a pilot study
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e55. doi: 10.1590/S1678-9946202163055. eCollection 2021.ABSTRACTLatent tuberculosis infection (LTBI) is a condition that has no clinical signs and symptoms. LTBI patients are characterized by persistent immune responses to Mycobacterium tuberculosis, and approximately 5-10% of these infected individuals will develop active TB at some point in their lives. The antigen transporter associated with antigen processing (TAP1) is a protein involved in the transport of the antigen from the cytoplasm to the endoplasmic reticulum by means of the association with MHC class I molecules. It pl...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Gerardo Cazarez-Navarro Jaime Palomares-Mar ín Sergio Yair Rodr íguez-Preciado Ana Laura Pereira-Su árez Erika Mart ínez-López Eva Adriana Bacilio-Medrano Selene Huerta-Olvera Iv án Isidro Hernández-Cañaveral Source Type: research

Basic knowledge about visceral leishmaniasis before and after educational intervention among primary health care professionals in Midwestern Brazil
This study assessed the impact of an educational intervention on the basic knowledge about visceral leishmaniasis (VL) among PHC professionals from the Brazilian municipality of Rondonopolis, an important endemic area for VL. Responses provided by physicians, nurses, nursing technicians and community health agents from 12 PHC facilities were recorded through the application of self-completed and semi-structured questionnaires before (n=92) and after (n=64) an in-person health training course covering various aspects of VL. Closed- and open-ended responses were compared by the chi-square test and analyses of word clouds, re...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Amanda Gabriela de Carvalho Isaac Alves Larissa Marquiori Borges Laura Bordignon Spessatto Ludiele Souza Castro Jo ão Gabriel Guimarães Luz Source Type: research

Cost-effectiveness analysis and budgetary impact of the Cryptococcal Antigen Lateral Flow Assay (CRAG-LFA) implementation for the screening and diagnosis of cryptococcosis in asymptomatic people living with HIV in Brazil
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e57. doi: 10.1590/S1678-9946202163057. eCollection 2021.ABSTRACTCryptococcal infection is a frequent cause of mortality in Brazilian HIV-infected patients. The present study aimed to evaluate the cost-effectiveness and budgetary impact of four cryptococcosis screening strategies in HIV-infected patients with CD4+ ≤ 200 cells/mm3, in Brazil. A Monte Carlo microsimulation was used to compare the following diagnostic tests: a systematic serum cryptococcal antigen (CRAG) screening with latex agglutination (CRAG-LA), a lateral flow immunochromatographic test (CRAG-LFA), India ink st...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Cid Manso de Mello Vianna Gabriela Bittencourt Gonzalez Mosegui Source Type: research

Early detection of SARS-CoV-2 P.1 variant in Southern Brazil and reinfection of the same patient by P.2
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e58. doi: 10.1590/S1678-9946202163058. eCollection 2021.ABSTRACTMultiple variants of the Severe Acute Respiratory Syndrome coronavirus 2 virus (SARS-CoV-2) have been constantly reported across the world. The B.1.1.28 lineage has been evolving in Brazil since February 2020 and originated the P.1 variant of concern (VOC), recently named as the Gamma variant by the newly WHO nomenclature proposal, and P.2 as a variant of interest (VOI). Here we describe an early case of P.1 primary infection in Southern Brazil in late November 2020, soon after the emergence of the variant in Manaus, ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Mariana Soares da Silva Meriane Demoliner Alana Witt Hansen Juliana Schons Gularte Fl ávio Silveira F ágner Henrique Heldt Micheli Filippi Vyctoria Malayhka de Abreu G óes Pereira Francini Pereira da Silva Larissa Mallmann Pietra Fink Luana Let ícia d Source Type: research

Safety issues of raw milk: evaluation of bacteriological and physicochemical characteristics of human milk from a bank in a teaching hospital, focusing on Staphylococcus species
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e54. doi: 10.1590/S1678-9946202163054. eCollection 2021.ABSTRACTMany infants are nurtured with milk supplied by human banks, whose bacteriological and physical-chemical profiles are a major issue. We investigated the bacteriological and physical-chemical characteristics, as well as genotypic and phenotypic and profiles of Staphylococcus species isolated from 240 samples of breast milk from a bank in a teaching hospital. Dornic acidity of milk revealed that 95.4% (229/240) had acceptable limits (
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Tatiana Salerno Amanda Keller Siqueira Jos é Paes de Almeida Nogueira Pinto Maria de Lourdes Ribeiro de Souza da Cunha Patr ícia Kelly Silvestre Larissa Anuska Zeni Condas Gustavo Henrique Batista Lara Juliano Gon çalves Pereira Aristeu Vieira da Silva Source Type: research

Association of TAP1 1177A & gt;G and 2090A & gt;G gene polymorphisms with latent tuberculosis infections in sheltered populations, in the metropolitan area of Guadalajara, Mexico: a pilot study
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e55. doi: 10.1590/S1678-9946202163055. eCollection 2021.ABSTRACTLatent tuberculosis infection (LTBI) is a condition that has no clinical signs and symptoms. LTBI patients are characterized by persistent immune responses to Mycobacterium tuberculosis, and approximately 5-10% of these infected individuals will develop active TB at some point in their lives. The antigen transporter associated with antigen processing (TAP1) is a protein involved in the transport of the antigen from the cytoplasm to the endoplasmic reticulum by means of the association with MHC class I molecules. It pl...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Gerardo Cazarez-Navarro Jaime Palomares-Mar ín Sergio Yair Rodr íguez-Preciado Ana Laura Pereira-Su árez Erika Mart ínez-López Eva Adriana Bacilio-Medrano Selene Huerta-Olvera Iv án Isidro Hernández-Cañaveral Source Type: research

Basic knowledge about visceral leishmaniasis before and after educational intervention among primary health care professionals in Midwestern Brazil
This study assessed the impact of an educational intervention on the basic knowledge about visceral leishmaniasis (VL) among PHC professionals from the Brazilian municipality of Rondonopolis, an important endemic area for VL. Responses provided by physicians, nurses, nursing technicians and community health agents from 12 PHC facilities were recorded through the application of self-completed and semi-structured questionnaires before (n=92) and after (n=64) an in-person health training course covering various aspects of VL. Closed- and open-ended responses were compared by the chi-square test and analyses of word clouds, re...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Amanda Gabriela de Carvalho Isaac Alves Larissa Marquiori Borges Laura Bordignon Spessatto Ludiele Souza Castro Jo ão Gabriel Guimarães Luz Source Type: research

Cost-effectiveness analysis and budgetary impact of the Cryptococcal Antigen Lateral Flow Assay (CRAG-LFA) implementation for the screening and diagnosis of cryptococcosis in asymptomatic people living with HIV in Brazil
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e57. doi: 10.1590/S1678-9946202163057. eCollection 2021.ABSTRACTCryptococcal infection is a frequent cause of mortality in Brazilian HIV-infected patients. The present study aimed to evaluate the cost-effectiveness and budgetary impact of four cryptococcosis screening strategies in HIV-infected patients with CD4+ ≤ 200 cells/mm3, in Brazil. A Monte Carlo microsimulation was used to compare the following diagnostic tests: a systematic serum cryptococcal antigen (CRAG) screening with latex agglutination (CRAG-LA), a lateral flow immunochromatographic test (CRAG-LFA), India ink st...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Cid Manso de Mello Vianna Gabriela Bittencourt Gonzalez Mosegui Source Type: research

Early detection of SARS-CoV-2 P.1 variant in Southern Brazil and reinfection of the same patient by P.2
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e58. doi: 10.1590/S1678-9946202163058. eCollection 2021.ABSTRACTMultiple variants of the Severe Acute Respiratory Syndrome coronavirus 2 virus (SARS-CoV-2) have been constantly reported across the world. The B.1.1.28 lineage has been evolving in Brazil since February 2020 and originated the P.1 variant of concern (VOC), recently named as the Gamma variant by the newly WHO nomenclature proposal, and P.2 as a variant of interest (VOI). Here we describe an early case of P.1 primary infection in Southern Brazil in late November 2020, soon after the emergence of the variant in Manaus, ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Mariana Soares da Silva Meriane Demoliner Alana Witt Hansen Juliana Schons Gularte Fl ávio Silveira F ágner Henrique Heldt Micheli Filippi Vyctoria Malayhka de Abreu G óes Pereira Francini Pereira da Silva Larissa Mallmann Pietra Fink Luana Let ícia d Source Type: research

Safety issues of raw milk: evaluation of bacteriological and physicochemical characteristics of human milk from a bank in a teaching hospital, focusing on Staphylococcus species
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e54. doi: 10.1590/S1678-9946202163054. eCollection 2021.ABSTRACTMany infants are nurtured with milk supplied by human banks, whose bacteriological and physical-chemical profiles are a major issue. We investigated the bacteriological and physical-chemical characteristics, as well as genotypic and phenotypic and profiles of Staphylococcus species isolated from 240 samples of breast milk from a bank in a teaching hospital. Dornic acidity of milk revealed that 95.4% (229/240) had acceptable limits (
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Tatiana Salerno Amanda Keller Siqueira Jos é Paes de Almeida Nogueira Pinto Maria de Lourdes Ribeiro de Souza da Cunha Patr ícia Kelly Silvestre Larissa Anuska Zeni Condas Gustavo Henrique Batista Lara Juliano Gon çalves Pereira Aristeu Vieira da Silva Source Type: research

Association of TAP1 1177A & gt;G and 2090A & gt;G gene polymorphisms with latent tuberculosis infections in sheltered populations, in the metropolitan area of Guadalajara, Mexico: a pilot study
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e55. doi: 10.1590/S1678-9946202163055. eCollection 2021.ABSTRACTLatent tuberculosis infection (LTBI) is a condition that has no clinical signs and symptoms. LTBI patients are characterized by persistent immune responses to Mycobacterium tuberculosis, and approximately 5-10% of these infected individuals will develop active TB at some point in their lives. The antigen transporter associated with antigen processing (TAP1) is a protein involved in the transport of the antigen from the cytoplasm to the endoplasmic reticulum by means of the association with MHC class I molecules. It pl...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Gerardo Cazarez-Navarro Jaime Palomares-Mar ín Sergio Yair Rodr íguez-Preciado Ana Laura Pereira-Su árez Erika Mart ínez-López Eva Adriana Bacilio-Medrano Selene Huerta-Olvera Iv án Isidro Hernández-Cañaveral Source Type: research

Basic knowledge about visceral leishmaniasis before and after educational intervention among primary health care professionals in Midwestern Brazil
This study assessed the impact of an educational intervention on the basic knowledge about visceral leishmaniasis (VL) among PHC professionals from the Brazilian municipality of Rondonopolis, an important endemic area for VL. Responses provided by physicians, nurses, nursing technicians and community health agents from 12 PHC facilities were recorded through the application of self-completed and semi-structured questionnaires before (n=92) and after (n=64) an in-person health training course covering various aspects of VL. Closed- and open-ended responses were compared by the chi-square test and analyses of word clouds, re...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Amanda Gabriela de Carvalho Isaac Alves Larissa Marquiori Borges Laura Bordignon Spessatto Ludiele Souza Castro Jo ão Gabriel Guimarães Luz Source Type: research

Cost-effectiveness analysis and budgetary impact of the Cryptococcal Antigen Lateral Flow Assay (CRAG-LFA) implementation for the screening and diagnosis of cryptococcosis in asymptomatic people living with HIV in Brazil
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e57. doi: 10.1590/S1678-9946202163057. eCollection 2021.ABSTRACTCryptococcal infection is a frequent cause of mortality in Brazilian HIV-infected patients. The present study aimed to evaluate the cost-effectiveness and budgetary impact of four cryptococcosis screening strategies in HIV-infected patients with CD4+ ≤ 200 cells/mm3, in Brazil. A Monte Carlo microsimulation was used to compare the following diagnostic tests: a systematic serum cryptococcal antigen (CRAG) screening with latex agglutination (CRAG-LA), a lateral flow immunochromatographic test (CRAG-LFA), India ink st...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Cid Manso de Mello Vianna Gabriela Bittencourt Gonzalez Mosegui Source Type: research

Early detection of SARS-CoV-2 P.1 variant in Southern Brazil and reinfection of the same patient by P.2
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e58. doi: 10.1590/S1678-9946202163058. eCollection 2021.ABSTRACTMultiple variants of the Severe Acute Respiratory Syndrome coronavirus 2 virus (SARS-CoV-2) have been constantly reported across the world. The B.1.1.28 lineage has been evolving in Brazil since February 2020 and originated the P.1 variant of concern (VOC), recently named as the Gamma variant by the newly WHO nomenclature proposal, and P.2 as a variant of interest (VOI). Here we describe an early case of P.1 primary infection in Southern Brazil in late November 2020, soon after the emergence of the variant in Manaus, ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Mariana Soares da Silva Meriane Demoliner Alana Witt Hansen Juliana Schons Gularte Fl ávio Silveira F ágner Henrique Heldt Micheli Filippi Vyctoria Malayhka de Abreu G óes Pereira Francini Pereira da Silva Larissa Mallmann Pietra Fink Luana Let ícia d Source Type: research

Safety issues of raw milk: evaluation of bacteriological and physicochemical characteristics of human milk from a bank in a teaching hospital, focusing on Staphylococcus species
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e54. doi: 10.1590/S1678-9946202163054. eCollection 2021.ABSTRACTMany infants are nurtured with milk supplied by human banks, whose bacteriological and physical-chemical profiles are a major issue. We investigated the bacteriological and physical-chemical characteristics, as well as genotypic and phenotypic and profiles of Staphylococcus species isolated from 240 samples of breast milk from a bank in a teaching hospital. Dornic acidity of milk revealed that 95.4% (229/240) had acceptable limits (
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Tatiana Salerno Amanda Keller Siqueira Jos é Paes de Almeida Nogueira Pinto Maria de Lourdes Ribeiro de Souza da Cunha Patr ícia Kelly Silvestre Larissa Anuska Zeni Condas Gustavo Henrique Batista Lara Juliano Gon çalves Pereira Aristeu Vieira da Silva Source Type: research

Association of TAP1 1177A & gt;G and 2090A & gt;G gene polymorphisms with latent tuberculosis infections in sheltered populations, in the metropolitan area of Guadalajara, Mexico: a pilot study
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e55. doi: 10.1590/S1678-9946202163055. eCollection 2021.ABSTRACTLatent tuberculosis infection (LTBI) is a condition that has no clinical signs and symptoms. LTBI patients are characterized by persistent immune responses to Mycobacterium tuberculosis, and approximately 5-10% of these infected individuals will develop active TB at some point in their lives. The antigen transporter associated with antigen processing (TAP1) is a protein involved in the transport of the antigen from the cytoplasm to the endoplasmic reticulum by means of the association with MHC class I molecules. It pl...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Gerardo Cazarez-Navarro Jaime Palomares-Mar ín Sergio Yair Rodr íguez-Preciado Ana Laura Pereira-Su árez Erika Mart ínez-López Eva Adriana Bacilio-Medrano Selene Huerta-Olvera Iv án Isidro Hernández-Cañaveral Source Type: research

Basic knowledge about visceral leishmaniasis before and after educational intervention among primary health care professionals in Midwestern Brazil
This study assessed the impact of an educational intervention on the basic knowledge about visceral leishmaniasis (VL) among PHC professionals from the Brazilian municipality of Rondonopolis, an important endemic area for VL. Responses provided by physicians, nurses, nursing technicians and community health agents from 12 PHC facilities were recorded through the application of self-completed and semi-structured questionnaires before (n=92) and after (n=64) an in-person health training course covering various aspects of VL. Closed- and open-ended responses were compared by the chi-square test and analyses of word clouds, re...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Amanda Gabriela de Carvalho Isaac Alves Larissa Marquiori Borges Laura Bordignon Spessatto Ludiele Souza Castro Jo ão Gabriel Guimarães Luz Source Type: research

Cost-effectiveness analysis and budgetary impact of the Cryptococcal Antigen Lateral Flow Assay (CRAG-LFA) implementation for the screening and diagnosis of cryptococcosis in asymptomatic people living with HIV in Brazil
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e57. doi: 10.1590/S1678-9946202163057. eCollection 2021.ABSTRACTCryptococcal infection is a frequent cause of mortality in Brazilian HIV-infected patients. The present study aimed to evaluate the cost-effectiveness and budgetary impact of four cryptococcosis screening strategies in HIV-infected patients with CD4+ ≤ 200 cells/mm3, in Brazil. A Monte Carlo microsimulation was used to compare the following diagnostic tests: a systematic serum cryptococcal antigen (CRAG) screening with latex agglutination (CRAG-LA), a lateral flow immunochromatographic test (CRAG-LFA), India ink st...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Cid Manso de Mello Vianna Gabriela Bittencourt Gonzalez Mosegui Source Type: research

Early detection of SARS-CoV-2 P.1 variant in Southern Brazil and reinfection of the same patient by P.2
Rev Inst Med Trop Sao Paulo. 2021 Jul 5;63:e58. doi: 10.1590/S1678-9946202163058. eCollection 2021.ABSTRACTMultiple variants of the Severe Acute Respiratory Syndrome coronavirus 2 virus (SARS-CoV-2) have been constantly reported across the world. The B.1.1.28 lineage has been evolving in Brazil since February 2020 and originated the P.1 variant of concern (VOC), recently named as the Gamma variant by the newly WHO nomenclature proposal, and P.2 as a variant of interest (VOI). Here we describe an early case of P.1 primary infection in Southern Brazil in late November 2020, soon after the emergence of the variant in Manaus, ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - July 7, 2021 Category: Tropical Medicine Authors: Mariana Soares da Silva Meriane Demoliner Alana Witt Hansen Juliana Schons Gularte Fl ávio Silveira F ágner Henrique Heldt Micheli Filippi Vyctoria Malayhka de Abreu G óes Pereira Francini Pereira da Silva Larissa Mallmann Pietra Fink Luana Let ícia d Source Type: research