Angiostrongylus cantonensis induces energy imbalance and dyskinesia in mice by reducing the expression of melanin-concentrating hormone
Infection with Angiostrongylus cantonensis (AC) in humans or mice can lead to severe eosinophilic meningitis or encephalitis, resulting in various neurological impairments. Developing effective neuroprotective dr... (Source: Parasites and Vectors)
Source: Parasites and Vectors - April 23, 2024 Category: Microbiology Authors: Hui Huang, Zhongyuan Zhang, Mengdan Xing, Zihan Jin, Yue Hu, Minyu Zhou, Hang Wei, Yiwen Liang and Zhiyue Lv Tags: Research Source Type: research

Echinococcus granulosus ubiquitin-conjugating enzymes (E2D2 and E2N) promote the formation of liver fibrosis in TGF β1-induced LX-2 cells
Cystic echinococcosis (CE) is a widespread zoonosis caused by the infection with Echinococcus granulosus sensu lato (E. granulosus s.l.). CE cysts mainly develop in the liver of intermediate hosts, characterized ... (Source: Parasites and Vectors)
Source: Parasites and Vectors - April 20, 2024 Category: Microbiology Authors: Xiaodi Du, Ruiqi Hua, Xue He, Wei Hou, Shengqiong Li, Aiguo Yang and Guangyou Yang Tags: Research Source Type: research

Phosphoproteomic analysis reveals changes in A-Raf-related protein phosphorylation in response to Toxoplasma gondii infection in porcine macrophages
Toxoplasma gondii is an obligate intracellular protozoan parasite that causes severe threats to humans and livestock. Macrophages are the cell type preferentially infected by T. gondii in vivo. Protein phosphoryl... (Source: Parasites and Vectors)
Source: Parasites and Vectors - April 20, 2024 Category: Microbiology Authors: Dingzeyang Su, Shifan Zhu, Kangzhi Xu, Zhaofeng Hou, Fuxing Hao, Fan Xu, Yifan Lin, Yuyang Zhu, Dandan Liu, Qiangde Duan, Xinjun Zhang, Yuguo Yuan, Jinjun Xu and Jianping Tao Tags: Research Source Type: research

Inhibition of Foxp3 expression in the placenta of mice infected intraperitoneally by toxoplasma gondii tachyzoites: insights into the PPAR γ/miR-7b-5p/Sp1 signaling pathway
Toxoplasma gondii, an obligate intracellular parasitic protozoa, infects approximately 30% of the global population. Contracting T. gondii at the primary infection of the mother can result in neonatal microcephal... (Source: Parasites and Vectors)
Source: Parasites and Vectors - April 17, 2024 Category: Microbiology Authors: Yue Zhong, Cheng Qin, Qing Wang, Maoyuan Ding, Chong Qiu, Yunzhao Xu and Jinling Chen Tags: Research Source Type: research

An optimised YOLOv4 deep learning model for efficient malarial cell detection in thin blood smear images
Malaria is a serious public health concern worldwide. Early and accurate diagnosis is essential for controlling the disease ’s spread and avoiding severe health complications. Manual examination of blood smear ... (Source: Parasites and Vectors)
Source: Parasites and Vectors - April 16, 2024 Category: Microbiology Authors: Dhevisha Sukumarran, Khairunnisa Hasikin, Anis Salwa Mohd Khairuddin, Romano Ngui, Wan Yusoff Wan Sulaiman, Indra Vythilingam and Paul Cliff Simon Divis Tags: Research Source Type: research

A first report of Pseudosuccinea columella (Say, 1817), an alien intermediate host for liver fluke, in Malawi
Starting in October 2021, quarterly malacological surveys have been undertaken in Malawi, with the sampling of 12 specified freshwater habitats throughout a calendar year. Each survey monitors the presence of ... (Source: Parasites and Vectors)
Source: Parasites and Vectors - April 11, 2024 Category: Microbiology Authors: S. Jones, A. Juh ász, P. Makaula, L. J. Cunningham, J. Archer, C. Nkolokosa, G. Namacha, E. Kambewa, D. Lally, D. R. Kapira, P. Chammudzi, S. A. Kayuni, J. Musaya and J. Russell Stothard Tags: Brief Report Source Type: research

High temperatures and low humidity promote the occurrence of microsporidians (Microsporidia) in mosquitoes (Culicidae)
In the context of climate change, a growing concern is that vector-pathogen or host-parasite interactions may be correlated with climatic factors, especially increasing temperatures. In the present study, we u... (Source: Parasites and Vectors)
Source: Parasites and Vectors - April 11, 2024 Category: Microbiology Authors: Artur Trzebny, Olena Nahimova and Miroslawa Dabert Tags: Research Source Type: research

Who was the first to visualize the malaria parasite?
Human malaria, an ancient tropical disease, is caused by infection with protozoan parasites belonging to the genus Plasmodium and is transmitted by female mosquitoes of the genus Anopheles. Our understanding of h... (Source: Parasites and Vectors)
Source: Parasites and Vectors - April 10, 2024 Category: Microbiology Authors: Emmanuel Drouin, Patrick Hautecoeur and Miles Markus Tags: Brief Report Source Type: research

Advances in the study of the interaction between schistosome infections and the host's intestinal microorganisms
Schistosomiasis, also called bilharziasis, is a neglected tropical disease induced by schistosomes that infects hundreds of millions of people worldwide. In the life cycle of schistosomiasis, eggs are regarded... (Source: Parasites and Vectors)
Source: Parasites and Vectors - April 10, 2024 Category: Microbiology Authors: Ao Hong, Abdulrahim Umar, Hao Chen, Zheng Yu and Jing Huang Tags: Review Source Type: research

Anopheles sacharovi in Italy: first record of the historical malaria vector after over 50 years
Anopheles sacharovi, a member of the Anopheles maculipennis complex, was a historical malaria vector in Italy, no longer found since the last report at the end of 1960s. In September 2022, within the Surveillance... (Source: Parasites and Vectors)
Source: Parasites and Vectors - April 10, 2024 Category: Microbiology Authors: Donato Antonio Raele, Francesco Severini, Luciano Toma, Michela Menegon, Daniela Boccolini, Giovanni Tortorella, Marco Di Luca and Maria Assunta Cafiero Tags: Brief Report Source Type: research

Laboratory evaluation of the contact irritancy of a clothianidin solo formulation vs. clothianidin-deltamethrin mixture formulations for indoor residual spraying against pyrethroid-resistant Anopheles gambiae sensu lato
Clothianidin-based indoor residual spraying (IRS) formulations have become available for malaria control as either solo formulations of clothianidin or a mixture of clothianidin with the pyrethroid deltamethri... (Source: Parasites and Vectors)
Source: Parasites and Vectors - April 10, 2024 Category: Microbiology Authors: Thomas Syme, Boris N ’dombidjé, Aicha Odjo, Martial Gbegbo, Damien Todjinou and Corine Ngufor Tags: Research Source Type: research

Anopheles aquatic development kinetic and adults ’ longevity through different seasons in laboratory and semi-field conditions in Burkina Faso
Anopheles mosquitoes are ectothermic and involved in numerous pathogen transmissions. Their life history traits are influenced by several environmental factors such as temperature, relative humidity and photoperi... (Source: Parasites and Vectors)
Source: Parasites and Vectors - April 8, 2024 Category: Microbiology Authors: Nicaise D. C. Dj ègbè, Dari F. Da, Bernard M. Somé, Lawata Inès G. Paré, Fatoumata Cissé, Wadaka Mamai, Karine Mouline, Simon P. Sawadogo, Joseph D. Challenger, Thomas S. Churcher and Roch K. Dabiré Tags: Research Source Type: research

Impact of environmental factors on Biomphalaria pfeifferi vector capacity leading to human infection by Schistosoma mansoni in two regions of western C ôte d'Ivoire
Intestinal schistosomiasis remains a worrying health problem, particularly in western C ôte d'Ivoire, despite control efforts. It is therefore necessary to understand all the factors involved in the development... (Source: Parasites and Vectors)
Source: Parasites and Vectors - April 5, 2024 Category: Microbiology Authors: Edwige A. Sokouri, Bernardin Ahouty Ahouty, Martial N ’Djetchi, Innocent A. Abé, Ble Gbacla Flora Dominique Yao, Thomas Konan Konan, Annette MacLeod, Harry Noyes, Oscar Nyangiri, Enock Matovu and Mathurin Koffi Tags: Research Source Type: research

Toxoplasma gondii modulates the host cell cycle, chromosome segregation, and cytokinesis irrespective of cell type or species origin
Toxoplasma gondii is an apicomplexan intracellular obligate parasite and the etiological agent of toxoplasmosis in humans, domestic animals and wildlife, causing miscarriages and negatively impacting offspring. D... (Source: Parasites and Vectors)
Source: Parasites and Vectors - April 5, 2024 Category: Microbiology Authors: Lisbeth Rojas-Baron, Kira Senk, Carlos Hermosilla, Anja Taubert and Zahady D. Vel ásquez Tags: Research Source Type: research

Efficacy of moxidectin, using various dose regimens, against JYD-34, a macrocyclic lactone resistant isolate of Dirofilaria immitis
Macrocyclic lactones (MLs) are the only class of drugs currently commercially available that are effective for preventing heartworm disease. The data presented in this article provide information on the effica... (Source: Parasites and Vectors)
Source: Parasites and Vectors - April 4, 2024 Category: Microbiology Authors: Elizabeth M. Martin, Elizabeth B. Mitchell, Stephen Yoon, John W. McCall, Becky Fankhauser, Abdelmoneim Mansour, Scott McCall and Matthias Pollmeier Tags: Research Source Type: research