Admission Characteristics and Mortality Risk Among Patients Hospitalized with COVID-19
No abstract available (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - September 1, 2021 Category: Infectious Diseases Tags: Letters to the Editor Source Type: research

Vancomycin-Induced Refractory Hypokalemia in a Pediatric Patient
No abstract available (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - September 1, 2021 Category: Infectious Diseases Tags: Letters to the Editor Source Type: research

Persistent SARS-CoV-2 positivity: An intriguing puzzle among reinfection, RNA remnants and genomic integration in COVID-19
No abstract available (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - September 1, 2021 Category: Infectious Diseases Tags: Letters to the Editor Source Type: research

Dermal Distress
No abstract available (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - September 1, 2021 Category: Infectious Diseases Tags: Images in ID—What's the Diagnosis? Source Type: research

Peculiar Palatal Lesion in a Patient Being Treated for Diabetic Ketoacedosis
No abstract available (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - September 1, 2021 Category: Infectious Diseases Tags: Images in ID—What's the Diagnosis? Source Type: research

Cytomegalovirus Reactivation After Bendamustine-Based Chemotherapy: A Case Report
Cytomegalovirus (CMV) is a DNA hepadnavirus, commonly implicated in reactivation disease after immunosuppression, especially in solid-organ and stem cell transplant patients. Bendamustine is an alkylating chemotherapeutic agent introduced into the management of hematological malignancies within the last decade. Few reports have raised potential concern for CMV reactivation disease after bendamustine therapy involving, but not limited to, the gastrointestinal tract, lungs, retina, and viremia. Cytomegalovirus reactivation in such instances should be added to the differential diagnoses for febrile nonneutropenic immunocompro...
Source: Infectious Diseases in Clinical Practice - September 1, 2021 Category: Infectious Diseases Tags: Case Reports Source Type: research

Pneumococcal Mastitis With Septicemia in a Pregnant Woman With Systemic Lupus Erythematosus
We report herein a case of a 37-year-old, pregnant, Japanese patient in her third trimester with systemic lupus erythematosus (SLE) who presented with bacteremic pneumococcal mastitis despite the absence of lactation. Previous studies suggested that a marked susceptibility to S. pneumoniae among patients with SLE may play an important role in the development of severe infections due to this organism. Clinicians should be aware of this susceptibility and the importance of pneumococcal vaccination for patients with SLE. (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - September 1, 2021 Category: Infectious Diseases Tags: Case Reports Source Type: research

An Isolated Presentation of Ischemic Retinal Vasculitis by the Great Masquerader: Mycobacterium tuberculosis With Literature Review
Ischemic retinal vasculitis is a sight-threatening inflammatory ocular condition that involves the retinal blood vessels. It is often associated with vascular occlusion and retinal hypoperfusion that may lead to neovascularization and subsequently preretinal and vitreous hemorrhages. It can be idiopathic or secondary to infection, neoplasia, or any other systemic diseases. Although it is rare, tuberculosis, which is an airborne disease caused by Mycobacterium tuberculosis, can manifest as retinal vasculitis without any evidence of pulmonary or other ocular structures involvement. (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - September 1, 2021 Category: Infectious Diseases Tags: Case Reports Source Type: research

An Unusual Case of Gordonia sputi Cerebral Infection
We present the first known case of G. sputi cerebral infection as a consequence of iatrogenic intrathecal chemotherapy through an Ommaya reservoir. The patient was successfully treated with a 14-day course of antibiotics without any further complications. There is sparse information on both infections due to and treatment of G. sputi. We present our case report as well as a review of the literature on the epidemiology, susceptibility, and treatment recommendations for G. sputi infections. (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - September 1, 2021 Category: Infectious Diseases Tags: Case Reports Source Type: research

A Case Report of the Hospital-Acquired Coronavirus Disease 2019 Pneumonia: Recognition of the Potential Exposure, Atypical Presentation, and Timeline on the Course of the Illness
This study presented a case of coronavirus disease 2019 pneumonia in a patient in isolation for 103 days. Severe acute respiratory syndrome coronavirus 2 was positive in her last 4 days. Despite policies of temperature checks for employees and visitors, and employees facing patients wearing a mask, the transmission of severe acute respiratory syndrome coronavirus 2 from an asymptomatic carrier was inevitable. (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - September 1, 2021 Category: Infectious Diseases Tags: Case Reports Source Type: research

COVID-19–Associated Eosinopenia in a Patient With Chronic Eosinophilia Due to Chronic Strongyloidiasis
We describe a case of a 59-year-old man who was treated with high-dose corticosteroids and anti-interleukin 1 receptor antagonist therapy because of severe acute respiratory distress syndrome due to a so-called cytokine storm in COVID-19. He had chronic eosinophilia for many years due to an unknown Strongyloides stercoralis infection, proven by serology and a positive polymerase chain reaction test on a stool sample. COVID-19 led to a complete resolution of eosinophilia, even before immunosuppressive treatment was started. Eosinophilia returned after recovery from COVID-19 and started to decline under treatment with iverme...
Source: Infectious Diseases in Clinical Practice - September 1, 2021 Category: Infectious Diseases Tags: Case Reports Source Type: research

Distribution of Hepatitis B Virus Genotypes, Subgenotypes, and Prevalence of Hepatitis B Virus Mutations in Untreated Patients With Chronic Hepatitis B From Mekong Delta
Background Drug resistance has become a major concern for antiviral therapy in patients with chronic hepatitis B (CHB), leading to an increased risk of treatment failure. We aimed to identify the prevalence of hepatitis B virus (HBV) DNA polymerase mutations and to determine the frequency of HBV genotypes and subgenotypes in treatment-naive patients with CHB in Mekong Delta, Vietnam. Methods Of the 550 drug-naive CHB patients from Mekong Delta, their serum samples were analyzed for HBV DNA mutations, genotypes, and subgenotypes using polymerase chain reaction sequencing. Results Of the 550 patients who we...
Source: Infectious Diseases in Clinical Practice - September 1, 2021 Category: Infectious Diseases Tags: Original Articles Source Type: research

Rates of Prophylaxis Among Pneumocystis jirovecii Pneumonia Cases Attributable to High-dose Steroid Therapy: A Single-center Experience
Background The incidence of Pneumocystis jirovecii pneumonia (PJP) among patients on high-dose steroid therapy is not well established, and few guidelines exist to help guide decisions regarding prophylaxis. We assessed provider prescribing practices regarding pneumocystis prophylaxis and conducted a retrospective chart review of 306 PJP cases at a tertiary care center to identify preventable cases and target interventions to reduce harm. Methods We surveyed providers regarding their threshold to initiate PJP prophylaxis among patients receiving steroid therapy. Subsequently, all encounters with a positive PJP P...
Source: Infectious Diseases in Clinical Practice - September 1, 2021 Category: Infectious Diseases Tags: Original Articles Source Type: research

Discontinuation of Transmission Precautions for COVID-19 Patients: Polymerase Chain Reaction Diagnostics, Patient Delays, and Cycle Threshold Values
Conclusions Concerns surround immunocompromised patients and those treated with steroids who might be delayed or incapable of stopping viral replication and thus remain contagious. Our results suggest that clinicians use all available data including Ct values to evaluate the safety of discontinuation of transmission precautions. (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - September 1, 2021 Category: Infectious Diseases Tags: Original Articles Source Type: research

Early Use of Remdesivir in Patients Hospitalized With COVID-19 Improves Clinical Outcomes: A Retrospective Observational Study
Conclusions Our data show that early treatment with remdesivir in patients hospitalized with COVID-19 shortened length of stay. (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - September 1, 2021 Category: Infectious Diseases Tags: Original Articles Source Type: research

Use of Industrial Filters by Health Care Workers During Shortages of N95 Respirators in Pandemic Times
The coronavirus disease 2019 (COVID-19) pandemic has led to a significant shortage of personal protective equipment in multiple health care facilities around the world, with the highest impact on N95 respirator masks. The N95 respirator is a mask that blocks at least 95% of very small (0.3 μm) particles and is considered a standard for enhanced respiratory precautions. The N95 mask shortage has created a need for other options for nasal and oral respiratory protection with similar filtration efficiency and “medical-grade” clearance, which can be used in health care settings. However, the literature around va...
Source: Infectious Diseases in Clinical Practice - September 1, 2021 Category: Infectious Diseases Tags: Review Articles Source Type: research

An Actinomyces Long-Bone Osteomyelitis Case Report and Review
We report a case of monomicrobial subacute late-onset tibia bone osteomyelitis involving Actinomyces presenting 10 years after an open reduction and internal fixation surgical procedure performed to stabilize a traumatic fracture and review actinomycotic osteomyelitis including the rare association of Actinomyces odontolyticus with long bone infections. (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - September 1, 2021 Category: Infectious Diseases Tags: Review Articles Source Type: research

A Case of Streptococcus intermedius Abscess Within a Malignant Neck Mass and Review of the Literature
Streptococcus intermedius is an organism found commensally in various mucosal sites. Over the past couple decades, it has been recognized as a cause of severe pyogenic infections in sites including the brain, liver, lung, head and neck. Here, we describe an uncommon case of S. intermedius infection in a patient with tonsillar squamous cell carcinoma and a metastatic neck mass with overlying postradiation skin changes. We also review the literature on this pathogen in cancer patients because it remains understudied despite its pathogenicity. (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - September 1, 2021 Category: Infectious Diseases Tags: Review Articles Source Type: research

Early Use of Remdesivir: A Good Start
No abstract available (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - September 1, 2021 Category: Infectious Diseases Tags: Editorial Comment Source Type: research

Delayed Skin Rash After Receiving SARS-CoV-2 mRNA Moderna Vaccine
No abstract available (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - July 1, 2021 Category: Infectious Diseases Tags: Letters to the Editor Source Type: research

Acute Necrotizing Rhombencephalitis and Disemminated Thrombosis After SARS-CoV-2 Infection
No abstract available (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - July 1, 2021 Category: Infectious Diseases Tags: Letters to the Editor Source Type: research

CDC Recommends Concurrent Immunizations: Does the COVID-19 Vaccination Campaign Offer Opportunities for Improving Vaccination Rates Across the Lifespan?
No abstract available (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - July 1, 2021 Category: Infectious Diseases Tags: Letters to the Editor Source Type: research

Fred's Fragment
No abstract available (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - July 1, 2021 Category: Infectious Diseases Tags: Images in ID—What's the Diagnosis? Source Type: research

Contiguous Mycotic Abdominal Aortic Aneurysm and Vertebral Osteomyelitis
No abstract available (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - July 1, 2021 Category: Infectious Diseases Tags: Images in ID—What's the Diagnosis? Source Type: research

Pulmonary Tuberculosis With Central Nervous System Streptococcus anginosus Coinfection in an Immunocompetent Man
We present a case of pulmonary TB and Streptococcus anginosus (SA) brain abscess in an immunocompetent middle-aged patient. This case presented with left upper and lower limb weakness and was found to have right-sided subdural empyema due to SA along with pulmonary TB. In cases of suspected CNS-TB, which develop neurological deterioration despite adequate treatment, an alternative microbiological diagnosis should be kept in the differentials. The CNS bacterial infections from the SA group occurring in concurrence with pulmonary TB can lead to severe complications. Timely neurosurgical intervention may be needed in such ins...
Source: Infectious Diseases in Clinical Practice - July 1, 2021 Category: Infectious Diseases Tags: Case Reports Source Type: research

An Atypical Neurocysticercosis Case Requiring Surgical Intervention
Cysticercosis, caused by tissue invasion of Taenia solium, is estimated to impact nearly 50 million people worldwide, particularly in areas with substandard sanitation and food handling measures. Neurologic dissemination of the larvae represents one of the most undertreated diseases worldwide despite being the leading cause of acquired epilepsy, prompting its addition to the list of major Neglected Tropical Diseases in 2010. Presenting symptoms are pleomorphic, ranging from asymptomatic to headaches and seizure activity. Therefore, high index for clinical suspicion is of utmost importance when obtaining history, particular...
Source: Infectious Diseases in Clinical Practice - July 1, 2021 Category: Infectious Diseases Tags: Case Reports Source Type: research

Treponema and Bartonella Coinfection in a Human Immunodeficiency Virus–Positive Individual
Infection with human immunodeficiency virus (HIV) leads to an acquired immunocompromised state, allowing for the rise of opportunistic infections. Here we present the first documented case, to our knowledge, of coinfection with Treponema pallidum and Bartonella henselae in an HIV (+) individual. (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - July 1, 2021 Category: Infectious Diseases Tags: Case Reports Source Type: research

Wound Infection With Enterococcus hirae Associated With Cat Litter
We report a case of wound infection caused by Enterococcus hirae in a 60-year-old woman with poorly controlled diabetes mellitus type II. She initially reported to the hospital because of chest pain and fatigue. During her hospital admission, an erythematous wound, measuring 1.5 cm in diameter, was discovered along the medial aspect of her right foot. Debridement of the wound revealed small pebbles, which the patient identified as cat litter. Wound cultures identified E. hirae, a known feline commensal organism and potential pathogen. Her wound was successfully treated with an inpatient course of intravenous ceftriaxone an...
Source: Infectious Diseases in Clinical Practice - July 1, 2021 Category: Infectious Diseases Tags: Case Reports Source Type: research

Pulmonary Thromboembolism Complicating Dengue Fever—The Other Side of Dengue!
We report a case of a 39-year-old lady who developed pulmonary thromboembolism during the first week of the illness with successful clinical outcome. The probable mechanisms of thrombosis and the treatment dilemma posed during the management of the patient are discussed. (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - July 1, 2021 Category: Infectious Diseases Tags: Case Reports Source Type: research

An Erratic Exanthem: Postvaricella Guillain-Barre Syndrome With Facial Diplegia
Varicella zoster (Chickenpox) usually occurs in childhood due to infection with varicella zoster virus. It manifests as an acute febrile exanthem which is usually self-limiting. Varicella zoster virus infection, in most cases, provides lifelong immunity to an individual after primary infection. In adults, primary varicella is uncommon, and most cases occur as a result of reactivation of the dormant virus. Subsequently, in adults, varicella infection can behave erratically to present with various unusual systemic and neurological complications, which are again uncommonly seen after primary varicella. The most common neurolo...
Source: Infectious Diseases in Clinical Practice - July 1, 2021 Category: Infectious Diseases Tags: Case Reports Source Type: research

Vaginal Malakoplakia: Cancer Mimicking Infection—A Case Review and Review of Literature
We present a case of a female patient who sought medical care for acute pelvic discomfort attributed to urinary retention after urinary obstruction. Although the discovery of multiple masses within the vagina and pelvic cavity indicated a tumor, it was originally negative for malignancy. Histology of biopsy samples demonstrated Michaelis-Gutmann bodies mixed with lymphoid cells through immunohistochemical and periodic acid–Schiff stains, consistent with a diagnosis of malakoplakia. Despite negative cultures, multiple courses of antibiotics were given, but the mass progressed and caused urinary obstruction. After pelv...
Source: Infectious Diseases in Clinical Practice - July 1, 2021 Category: Infectious Diseases Tags: Immunology/Microbiology for ID Source Type: research

The Response of Medical Doctors and Hospital Administration to Infection Prevention and Control in the Health Care of Suspected/Confirmed COVID-19 Patients
Conclusions The doctors reported that we adhere to infection prevention in providing health care, in contrast with hospital administration. (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - July 1, 2021 Category: Infectious Diseases Tags: Original Articles Source Type: research

Identifying Social Determinants of Health and Allocating Resources During the COVID-19 Pandemic
Conclusions By identifying needed barriers via telemedicine, we can properly allocate resources to those who need it the most and hope to decrease the potential long-term effects of this current pandemic. (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - July 1, 2021 Category: Infectious Diseases Tags: Original Articles Source Type: research

Tocilizumab for Severe and Critical COVID-19 Pneumonia in Queens, NYC
Conclusions Tocilizumab failed to show short-term benefits in clinical outcomes in patients with hypoxic COVID pneumonia at our institution. (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - July 1, 2021 Category: Infectious Diseases Tags: Original Articles Source Type: research

Rat-Bite Fever Due to Streptobacillus moniliformis: A Case Series From New South Wales, Australia, and Literature Review
Conclusions The case series and literature review of rat-bite fever describe a characteristic clinical picture with fever, arthritis, and rash; a history of rat exposure is supportive, and blood cultures with current laboratory techniques are usually diagnostic. (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - July 1, 2021 Category: Infectious Diseases Tags: Review Articles Source Type: research

Listeria Rhomboencephalitis in an Immunocompetent Host: Treatment With Trimethoprim-Sulfamethoxazole and Ampicillin: A Case Report and Review of Treatment Options
We present this case to highlight the syndrome of listeria rhomboencephalitis and the evolving treatment options. (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - July 1, 2021 Category: Infectious Diseases Tags: Review Articles Source Type: research

Protecting Vulnerable Patients from Influenza During the COVID-19 Pandemic: An Urgent Call to Action for Health Care Professionals
The 2020–2021 US influenza season, although mild, initially raised concerns about an unprecedented dual threat of SARS-CoV-2, the virus that causes COVID-19, circulating alongside seasonal influenza viruses. Although everyone is susceptible to influenza infection, adults with chronic health conditions (including heart disease, lung disease, and diabetes) are particularly vulnerable to influenza-related complications including hospitalization, disability, and death—as are older adults (65+ years) and adults in underserved communities, in which rates of chronic health conditions are higher. Many of the chronic he...
Source: Infectious Diseases in Clinical Practice - July 1, 2021 Category: Infectious Diseases Tags: NFID Clinical Updates Source Type: research

Tocilizumab and SARS-CoV-2 (COVID-19): An Evolving Story, the Picture Is Clearer
No abstract available (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - July 1, 2021 Category: Infectious Diseases Tags: Editorial Comment Source Type: research

Music Therapy for the Treatment of Patients With COVID-19: Psychopathological Problems Intervention and Well-Being Improvement
No abstract available (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - May 1, 2021 Category: Infectious Diseases Tags: Letters to the Editor Source Type: research

Diabetes and Risk of COVID-19 Mortality: A Systematic Review and Meta-Analysis
No abstract available (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - May 1, 2021 Category: Infectious Diseases Tags: Letters to the Editor Source Type: research

Postinfectious Interstitial Pneumonia After COVID-19 Infection
No abstract available (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - May 1, 2021 Category: Infectious Diseases Tags: Letters to the Editor Source Type: research

Ganciclovir Therapy for CMV Viremia in a Patient on VV ECMO With COVID-19 After Treatment With Tocilizumab
No abstract available (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - May 1, 2021 Category: Infectious Diseases Tags: Letters to the Editor Source Type: research

A Sinister Trail of Infections in a Young Boy
No abstract available (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - May 1, 2021 Category: Infectious Diseases Tags: Images in ID—What's the Diagnosis? Source Type: research

A Child With Kawasaki Disease and Coronary Artery Aneurysm During Acute Epstein-Barr Virus Infection: A Closer Look at Immunopathogenesis
We describe an 18-month-old toddler boy who developed clinical manifestations of KD with coronary artery aneurysmal dilatation and autoimmune hemolytic anemia during Epstein-Barr virus infection. The child had evidence of polyclonal activation of B cells that caused serological tests to be positive for different infections. Our case suggests an unusual immunological response to primary Epstein-Barr virus infection may lead to KD manifestation and coronary artery damage. (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - May 1, 2021 Category: Infectious Diseases Tags: Case Reports Source Type: research

Unveiling the Potential Threat of Bacterial Oral Flora of Snake in Snake Bite Envenomation: A Case Report
Snakebite is an acute life-threatening and time-limited medical emergency. There is comparatively less evidence regarding the infections caused by pathogens present in the snake's oral flora that induce cellulites secondary to snake bite. Here, we report a case of 15-year-old male patient infected with Acinetobacter baumannii–induced sepsis who underwent hemodialysis posthemotoxic envenomation; inflicted by hemotoxic snake, Russell's viper (Daboia russelii) at right index finger, and he was treated with 20 vials of antisnake venom. He had acute kidney injury and underwent 10 cycles of hemodialysis. He had incidence o...
Source: Infectious Diseases in Clinical Practice - May 1, 2021 Category: Infectious Diseases Tags: Case Reports Source Type: research

How Negative Is Culture-Negative Endocarditis in the Presence of a Pacemaker?
A case report of a 70-year-old man with pacemaker placed for atrial fibrillation in 1999 (generator change in 2016). His illness began 4 months earlier with “hots-and-colds” sensation for which he was admitted to an outside hospital and treated for community-acquired pneumonia for 7 days. Fevers persisted after discharge, and he received a 7-day doxycycline course 1 week later. Persistent fevers led to a second admission at the outside hospital. Infectious workup was negative but transesophageal echocardiography showed mass on pacemaker lead so he was transferred to our hospital. No mass on repeat transesophage...
Source: Infectious Diseases in Clinical Practice - May 1, 2021 Category: Infectious Diseases Tags: Case Reports Source Type: research

Very Rare Gastrointestinal Anthrax in a Pregnant Woman
In this study, we reported a 38-years-old pregnant woman who was referred to the hospital with abdominal pain and persistent hemorrhagic diarrhea. Suzerain operation was also used, and laparotomy showed necrotic gangrene in colon. After the first surgery, the patient showed left lower quadrant abdominal pain (left lower quadrant collection), and drainage was performed during the second surgery. Finally, after 20 days, the patient was recovered and discharged from the hospital in a very good condition. Gastrointestinal anthrax during pregnancy is a very rare condition. In this study, we reported a patient with gastrointesti...
Source: Infectious Diseases in Clinical Practice - May 1, 2021 Category: Infectious Diseases Tags: Case Reports Source Type: research

Primary Epstein-Barr Virus Infection With Marked Cholestasis, Warm Autoimmune Hemolytic Anemia, and Pancytopenia
Primary Epstein-Barr virus (EBV) infection may rarely present with cholestatic hepatitis or hemolytic anemia. We share a case of EBV-associated infectious mononucleosis presenting with a unique triad of findings comprising cholestatic hepatitis with marked hyperbilirubinemia, warm autoimmune hemolytic anemia, and pancytopenia. Early diagnostic challenges included negative Monospot heterophile testing. Additional testing revealed EBV serologies consistent with acute primary infection, EBV viremia and bone marrow biopsy showing EBV-encoded RNA–positive cells. A tapered prednisone course was administered for warm autoim...
Source: Infectious Diseases in Clinical Practice - May 1, 2021 Category: Infectious Diseases Tags: Case Reports Source Type: research

Multisystem Inflammatory Syndrome in an Adult With COVID-19
We present the case of a 39-year-old man with evidence of prior COVID-19 who seemed to meet all non–age-related criteria for MIS in children as well as criteria for the working definition of MIS in adults, and who improved after treatment with aspirin, corticosteroids, and intravenous immunoglobulin. Clinicians should be aware of this new inflammatory illness, not only in children but potentially also in adults with antecedent or concurrent COVID-19. (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - May 1, 2021 Category: Infectious Diseases Tags: Case Reports Source Type: research

Why Is a Child Not a Miniadult for Infections?
The presentation of an infectious disease in a child is likely to differ from an adult and will differ at different ages of the child. In addition to differences in immune response, there are significant differences in anatomy, physiology, metabolism, and behavior that affect susceptibility, course of disease, severity, and treatment. This is the first of a series of reviews that examine differences in disease presentation for different demographics. This short review will look at some of the parameters that ask, “Why is a child not a miniadult for infections?” (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - May 1, 2021 Category: Infectious Diseases Tags: Immunology/Microbiology for ID Source Type: research