The rash with maculopapules and fever in adults

We describe various conditions that result in a fever and maculopapular rash in adults. These include infectious processes (meningococcemia, infectious mononucleosis, West Nile virus, zika virus, rubella, primary human immunodeficiency virus, parvovirus B19, ebolavirus), tick-borne illnesses (Rocky Mountain spotted fever, ehrlichiosis), and hypersensitivity reactions (exanthematous drug reactions).
Source: Clinics in Dermatology - Category: Dermatology Authors: Source Type: research

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CARLSBAD, Calif., Sept. 18, 2019 -- (Healthcare Sales &Marketing Network) -- ChromaCode, Inc., a next-generation molecular diagnostics company using data science to significantly enhance multiplexing capabilities of life science instrumentation, today an... Diagnostics ChromaCode, HDPCR, tick-borne pathogens
Source: HSMN NewsFeed - Category: Pharmaceuticals Source Type: news
Date: Tuesday, 09 24, 2019; Speaker: Dr. Rachel Abrams, NINDS; Dr. Avi Nath, NINDS; Building: Building 10 (Clinical Center); Lipsett Auditorium; CME Credit
Source: NIH Calendar of Events - Category: American Health Source Type: events
Current guidelines recommend parvovirus revaccination of adult dogs no more frequently than every 3  years. The aim of this study was to determine the prevalence of dogs showing protective serum antibody titres...
Source: BMC Veterinary Research - Category: Veterinary Research Authors: Tags: Research article Source Type: research
Epstein-Barr virus (EBV) infects most people and establishes life-long infection controlled by the host's immune system. The genetic stability of the virus, deep understanding of the viral antigens and immune epitopes recognized by the host's T-cell system and the fact that recent infection can be identified by the development of symptomatic infectious mononucleosis makes EBV a powerful system in which to study human immunology. The association between EBV and multiple cancers also means that the lessons learned have strong translational potential. Increasing evidence of a role for resident memory T-cells and non-conventio...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
The blood–brain barrier (BBB) selectively regulates the cellular exchange of macromolecules between the circulation and the central nervous system (CNS). Here, we hypothesize that Zika virus (ZIKV) infects the brain via a disrupted BBB and altered expression of tight junction (TJ) proteins, which are structural components of the BBB. To assess this hypothesis, in vitro and in vivo studies were performed using three different strains of ZIKV: Honduras (ZIKV-H), Puerto Rico (ZIKV-PR), and Uganda (ZIKV-U). Primary human brain microvascular endothelial cells (BMECs) were productively infected by all studied ZIKV strains ...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Semin Neurol 2019; 39: 419-427 DOI: 10.1055/s-0039-1687839There are many arthropod-borne viruses (arboviruses) capable of neuroinvasion, with West Nile virus being one of the most well known. In this review, we highlight five rarer emerging or reemerging arboviruses capable of neuroinvasion: Cache Valley, eastern equine encephalitis, Jamestown Canyon, Powassan, and Usutu viruses. Cache Valley and Jamestown Canyon viruses likely circulate throughout most of North America, while eastern equine encephalitis and Powassan viruses typically circulate in the eastern half. Usutu virus is not currently circulating in North America,...
Source: Seminars in Neurology - Category: Neurology Authors: Tags: Review Article Source Type: research
Semin Neurol 2019; 39: 440-447 DOI: 10.1055/s-0039-1692143Tick-borne infections—including tick-borne encephalitis viruses, represented in the United States by rare infections with Powassan and deer tick viruses, and more often Lyme disease—are of increasing importance to neurologists. Lyme neuroborreliosis (LNB) causes all or part of a triad including meningitis, radiculoneuritis, and cranial neuritis. Rarely, parenchymal brain and spinal cord involvement occur, with focal findings on examination and magnetic resonance imaging (MRI). LNB diagnosis requires plausible exposure, objective evidence of nervous syste...
Source: Seminars in Neurology - Category: Neurology Authors: Tags: Review Article Source Type: research
Authors: BrodziƄski S, Nasierowski T Abstract In the second part of the article case reports of three patients were presented. All patientswere treated for Borrelia infection and all of them developed psychotic disorders. History of each patient was different, as well as the probability of causal relationship between neuroborreliosis and psychosis. The first case concerns a female patient with no former psychiatric history, who developed psychotic episode secondary to neuroborreliosis. Psychotic disorders resolved after antibiotic treatment. In the second case, a male patient was previously twice hospitalized in p...
Source: Psychiatria Polska - Category: Psychiatry Tags: Psychiatr Pol Source Type: research
[The Herald] ZIMBABWE will next week hold a national measles-rubella vaccination campaign for children under the age of five, following a "dangerous" measles comeback, the World Health Organisation (WHO) has revealed.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Zika virus (ZIKV) is an arthropod-borne flavivirus predominantly transmitted by Aedes aegypti mosquitoes and poses a global human health threat. All flaviviruses, including those that exclusively replicate in mosquitoes, produce a highly abundant, noncoding subgenomic flavivirus RNA (sfRNA) in infected cells, which implies an important function of sfRNA during mosquito...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: PNAS Plus Source Type: research
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