Vector-borne Diseases: An Ongoing Threat

Vector-borne diseases (VBDs) are responsible for significant morbidity and mortality worldwide. In the United States, VBDs continue to increase, with 9 new VBDs identified since 2004 and most recently in 2017 a new vector, Haemaphysalis longicornis. Vectors such as ticks, mosquitoes, and fleas are capable of transmitting bacteria, viruses, and parasites. This updated review of the current recommendations for the diagnosis and treatment of Lyme disease, Rocky Mountain spotted fever, ehrlichiosis, and West Nile virus will help prepare nurse practitioners to provide safe, competent care for their patients and communities at large.
Source: The Journal for Nurse Practitioners - Category: Nursing Authors: Tags: Feature Article Source Type: research

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The opioid epidemic has plagued the United States with high levels of abuse and poor quality of life for chronic pain patients requiring continuous use of opioids. New drug discovery efforts have been implemented to mitigate this epidemic; however, new medications are still limited by low efficacy and/or high side effect and abuse potential. Intermittent fasting (IF) has recently been shown to improve a variety of pathological states, including stroke and neuroinflammation. Numerous animal and human studies have shown the benefits of IF in these disease states, but not in pain and opioid treatment. We thus subjected male a...
Source: Pain - Category: Anesthesiology Tags: Research Paper Source Type: research
CONCLUSION: Early SVG failure occurred in approximately one-third of patients. Prasugrel did not decrease prevalence of SVG thrombus 12 months after CABG. PMID: 32961528 [PubMed - as supplied by publisher]
Source: The Journal of Invasive Cardiology - Category: Cardiology Tags: J Invasive Cardiol Source Type: research
Authors: Brunetti P, Lo Faro AF, Pirani F, Berretta P, Pacifici R, Pichini S, Busardò FP Abstract Cannabidiol (CBD) is the second most abundant cannabinoid present in Cannabis sativa L. It is not associated with psychotropic activity and is capable to mitigate the psychotomimetic effects produced by tetrahydrocannabinol (THC). The latest cannabis decriminalization policies and the high applicability in therapeutic and technologic-industrial fields, have determined an exponential marketing growth of foods, cosmetics and in particularly medicinal products containing CBD, which are easily available for consumer...
Source: Annali dell Istituto Superiore di Sanita - Category: General Medicine Tags: Ann Ist Super Sanita Source Type: research
Giardia intestinalis is a microaerophilic protozoan that is an important etiologic agent of diarrhea worldwide. There is evidence that under diverse conditions, the parasite is capable of shedding extracellular vesicles (EVs) which modulate the physiopathology of giardiasis. Here we describe new features of G. intestinalis EV production, revealing its capacity to shed two different enriched EV populations: large (LEV) and small extracellular vesicles (SEV) and identified relevant adhesion functions associated with the larger population. Proteomic analysis revealed differences in proteins relevant for virulence and host-pat...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
Publication date: November 2020Source: Epilepsy &Behavior, Volume 112Author(s): Alain Lekoubou, Matthew Pelton, Kinfe G. Bishu, Bruce Ovbiagele
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
Publication date: November 2020Source: Epilepsy &Behavior, Volume 112Author(s): Yousef N. Alharbi
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
Jeff VandersliceOn Monday, the House of Representatives passed theDue Process Protections Act (S. 1380) by unanimous consent after having received it from the Senate, which unanimously passed the bill in May. The legislation is now headed to the White House where it is expected to receive President Trump ’s signature.The bill reinforces an existing constitutional obligation of prosecutors to disclose so ‐​calledBradymaterial – material that is favorable to the defense – and facilitates the disciplining of federal prosecutors who fail to uphold their obligation to do so.Those who regularly follow this ...
Source: Cato-at-liberty - Category: American Health Authors: Source Type: blogs
This week, I did something unplanned: I bought 2 vials of Lilly's " authorized generic " of its brand-name U-100 insulin analog branded as Humalog (insulin lispro rDNA origin) at my neighborhood Walgreens. The reason it was unplanned is because I already met the deductible for my insurance plan, so I hadn't expected to deal with this until it resets in January. But I had a script I last filled before I met the deductible, and the pharmacy sent a text telling me it was time to refill. In reality, I have insulin but its a different brand and a different pharmacy. But Walgreens wants a sale so it was telling me it i...
Source: Scott's Web Log - Category: Endocrinology Tags: Admelog Drug Channels drug prices GoodRx Humalog insulin Lilly prescriptions rebates Sanofi Source Type: blogs
Authors: Choi YJ, Görg M, Shin HD, Thines M Abstract Over the past 15 years, downy mildew became the most destructive foliar disease in cultivated Impatiens species (Balsaminaceae) worldwide. A previous study had revealed that the causal agent was not Plasmopara obducens (Oomycota, Peronosporales) but Plasmopara destructor on Impatiens walleriana, and Plasmopara velutina on Impatiens balsamina. This hints to a relatively high degree of specialization of Plasmopara on Balsaminaceae. Therefore, it was the aim of the present study to perform multigene phylogenetic analysis and detailed morphological investigation...
Source: Mycobiology - Category: Biology Tags: Mycobiology Source Type: research
Today, approximately 20% of the U.S. population — about 60 million people — live in rural areas, which make up 97% of the land area in the United States. People living in rural America have less access to health care and are more likely than residents of urban areas to die from chronic conditions such as heart disease, cancer, stroke, and chronic lower respiratory disease. Moreover, long-standing systemic health and social inequities have put many rural residents at increased risk of getting COVID-19. The rural/urban inequities in health and health care warrant more rigorous and innovative scientific research t...
Source: Videocast - All Events - Category: General Medicine Tags: Upcoming Events Source Type: video
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