Recurrence in lobular carcinoma of the breast: A 14-year review
CONCLUSION: There are clinical implications for the management and follow-up for patients with a diagnosis of lobular cancer of the breast. Due to the low recurrence rate, now, the standard practice in our institution does not offer magnetic resonance imaging (MRI) as part of the follow-up for ILC patients. Other centres should establish local recurrence rates to aid development of appropriate management protocols.PMID:38804125 | DOI:10.1111/1754-9485.13715 (Source: Clin Med Res)
Source: Clin Med Res - May 28, 2024 Category: Research Authors: Nathan Burns Anita Bourke Source Type: research
Pulmonary neuroendocrine tumors : Current review
Radiologie (Heidelb). 2024 May 28. doi: 10.1007/s00117-024-01319-8. Online ahead of print.ABSTRACTCLINICAL ISSUE: Neuroendocrine neoplasms of the lung are a heterogenous tumor group. The pathological classification comprises diffuse idiopathic pulmonary neuroendocrine cell hyperplasia, classic neuroendocrine tumors, and neuroendocrine carcinoma. Classic neuroendocrine tumors include typical and atypical carcinoid tumors.DIAGNOSTIC WORK-UP: Imaging plays an important role in diagnosis and can help in identifying the tumor biology. Overall, this tumor group is rare, comprising less than 2% of all thoracic tumors.PRACTICAL RE...
Source: Nuklearmedizin - May 28, 2024 Category: Radiology Authors: Hans-Jonas Meyer Armin Frille Solveig Tiepolt Timm Denecke Source Type: research
Bioinformatics Identification and Experimental Validation of a Prognostic Model for the Survival of Lung Squamous Cell Carcinoma Patients
In conclusion, the cuproptosis-based genes predictive risk model can be utilized to predict outcomes, track immune function, and evaluate medication sensitivity in LUSC patients.PMID:38806973 | DOI:10.1007/s10528-024-10828-z (Source: Biochemical Genetics)
Source: Biochemical Genetics - May 28, 2024 Category: Genetics & Stem Cells Authors: Hongtao Zhao Ruonan Sun Lei Wu Peiluo Huang Wenjing Liu Qiuhong Ma Qinyuan Liao Juan Du Source Type: research
The Burden of Multiple Basal Cell Carcinomas: A Population-wide Study
This study showed the cumulative risk of a subsequent BCC to increase with a history of multiple BCCs, indicating the need for clinical surveillance in these individuals.PMID:38803206 | DOI:10.2340/actadv.v104.40112 (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - May 28, 2024 Category: Dermatology Authors: Johan Kappelin Ingela Ahnlide Åsa Ingvar Kari Nielsen Source Type: research
Efficacy and safety of lenvatinib combined with PD ‑1/PD‑L1 inhibitors in the treatment of hepatocellular carcinoma: A meta‑analysis and systematic review
Oncol Lett. 2024 May 14;28(1):312. doi: 10.3892/ol.2024.14445. eCollection 2024 Jul.ABSTRACTA meta-analysis of the clinical survival indicators, adverse reactions and safety of lenvatinib combined with programmed death-1 (PD-1) inhibitors in treating liver cancer was conducted, providing objective and effective evidence for clinical use. The present study is anticipated to guide the clinical application of lenvatinib. In the current meta-analysis, the PubMed, Embase and Cochrane Library databases were searched from inception to September 2023. Randomized controlled trials (RCTs), non-RCTs and single-arm trial studies relat...
Source: Oncology Letters - May 28, 2024 Category: Cancer & Oncology Authors: Baoyan Zhang Linfeng Su Yonghua Lin Source Type: research
Redefining the standard of care for low-grade serous ovarian cancer
Clin Adv Hematol Oncol. 2024 Jun;22(5):205-226.ABSTRACTLow-grade serous carcinoma is a rare epithelial ovarian cancer subtype with distinct clinical, histologic, and molecular features. Improved understanding of this disease subtype has prompted recent advances in treatment options. Although low-grade serous carcinoma historically has been treated following a high-grade serous carcinoma paradigm, new data have called into question the utility of platinum retreatment, addressed the possibility of first-line hormonal treatment, and brought forth therapeutic options targeting the MAPK pathway and cyclin D kinase in low-grade ...
Source: Clinical Advances in Hematology and Oncology - May 28, 2024 Category: Cancer & Oncology Authors: Beryl L Manning-Geist Tal Cantor R óisín E O'Cearbhaill Rachel N Grisham Source Type: research
The Burden of Multiple Basal Cell Carcinomas: A Population-wide Study
This study showed the cumulative risk of a subsequent BCC to increase with a history of multiple BCCs, indicating the need for clinical surveillance in these individuals.PMID:38803206 | DOI:10.2340/actadv.v104.40112 (Source: Acta Derm Venereol A...)
Source: Acta Derm Venereol A... - May 28, 2024 Category: Dermatology Authors: Johan Kappelin Ingela Ahnlide Åsa Ingvar Kari Nielsen Source Type: research
Risk versus Benefit of Tyrosine Kinase Inhibitors for Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Clin Pharmacol Ther. 2024 May 27. doi: 10.1002/cpt.3312. Online ahead of print.ABSTRACTAlthough the treatment landscape has rapidly evolved over the last years, hepatocellular carcinoma (HCC) is one of the most lethal cancers. With recent advances, both immunotherapy and tyrosine kinase inhibitors (TKIs)-based chemotherapy constitute the standard treatment for advanced HCC. A systematic search of randomized clinical trials employing TKIs was performed in 17 databases, obtaining 25 studies evaluating the prognosis, tumor response, and presence of adverse events (AEs) related to TKIs in HCC. Overall effect sizes were estimat...
Source: Clinical Pharmacology and Therapeutics - May 28, 2024 Category: Drugs & Pharmacology Authors: Tania Payo-Seraf ín Carolina M éndez-Blanco Paula Fern ández-Palanca Jennifer Mart ínez-Geijo Mar ía Reviejo Juan Jos é Ortiz-de-Urbina Javier Gonz ález-Gallego Jose J G Marin Jos é L Mauriz Beatriz San-Miguel Source Type: research
Recurrence in lobular carcinoma of the breast: A 14-year review
CONCLUSION: There are clinical implications for the management and follow-up for patients with a diagnosis of lobular cancer of the breast. Due to the low recurrence rate, now, the standard practice in our institution does not offer magnetic resonance imaging (MRI) as part of the follow-up for ILC patients. Other centres should establish local recurrence rates to aid development of appropriate management protocols.PMID:38804125 | DOI:10.1111/1754-9485.13715 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - May 28, 2024 Category: Cancer & Oncology Authors: Nathan Burns Anita Bourke Source Type: research
Efficacy of Lenvatinib in Combination With PD-1 Monoclonal Antibody and Interventional Treatment for Intermediate-Stage Hepatocellular Carcinoma: Impact on Serum Vascular Endothelial Growth Factor and Matrix Metalloproteinase-9 Levels: A Retrospective Study
Conclusion: The combined use of lenvatinib, PD-1 monoclonal antibody, and interventional treatment for intermediate to advanced hepatocellular carcinoma may have a definitive therapeutic efficacy. This regimen is effective in reducing tumor marker levels, enhancing immune function, modulating VEGF, MMP-9, and other related cytokine levels, and improving patients' quality of life without significantly augmenting adverse effects. This treatment paradigm also contributes to increased survival rates and promises favorable prognosis.PMID:38802996 | DOI:10.1177/15330338241256812 (Source: Technology in Cancer Research and Treatment)
Source: Technology in Cancer Research and Treatment - May 28, 2024 Category: Cancer & Oncology Authors: Jianyong Zhu Yintao Wu Hong Zhang Jian Yang Yang An Shihan Shao Nianxin Xia Source Type: research
Detection of Muscularis propria Invasion in Urothelial Carcinoma Using Artificial Intelligence
Conclusion: The algorithm we developed may greatly aid in accurate identification of muscularis propria invasion by imitating the thought process of the pathologist.PMID:38803309 | DOI:10.1177/15330338241257479 (Source: Technology in Cancer Research and Treatment)
Source: Technology in Cancer Research and Treatment - May 28, 2024 Category: Cancer & Oncology Authors: Ibrahim Fahoum Rabab Naamneh Keren Silberberg Rami Hagege Dov Hershkovitz Source Type: research
Recurrence in lobular carcinoma of the breast: A 14-year review
CONCLUSION: There are clinical implications for the management and follow-up for patients with a diagnosis of lobular cancer of the breast. Due to the low recurrence rate, now, the standard practice in our institution does not offer magnetic resonance imaging (MRI) as part of the follow-up for ILC patients. Other centres should establish local recurrence rates to aid development of appropriate management protocols.PMID:38804125 | DOI:10.1111/1754-9485.13715 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - May 28, 2024 Category: Cancer & Oncology Authors: Nathan Burns Anita Bourke Source Type: research
3-Fr steerable microcatheter system via the upper limb artery in RADPLAT for right maxillary cancer
CONCLUSION: Using a 3-Fr catheter system with a steerable microcatheter through right upper limb artery access is a feasible method for RADPLAT in treating right MS-SCC.PMID:38804569 | DOI:10.1080/13645706.2024.2359718 (Source: Minimally Invasive Therapy and Allied Technologies)
Source: Minimally Invasive Therapy and Allied Technologies - May 28, 2024 Category: Surgery Authors: Masao Takahashi Ken Nakazawa Yoko Usami Yuki Natsuyama Yuichi Tsukamoto Jun Suzuki Shiho Asami Hitoshi Inoue Satoko Matsumura Mitsuhiko Nakahira Tetsu Saito Shingo Kato Yoshitaka Okada Hiroyuki Tajima Eito Kozawa Yasutaka Baba Source Type: research
Cost-effectiveness analysis of tislelizumab vs. camrelizumab for the treatment of second-line locally advanced or metastatic esophageal squamous cell carcinoma
CONCLUSION: Tislelizumab monotherapy is a dominant option compared with camrelizumab monotherapy as the second-line treatment for locally advanced or metastatic ESCC in China.PMID:38807104 | DOI:10.1186/s12913-024-11142-5 (Source: Cell Research)
Source: Cell Research - May 28, 2024 Category: Cytology Authors: Pingyu Chen Chang Fu Lin Shen Zhengyang Fei Mengjie Luo Yanqiu Chen Hongchao Li Source Type: research
Detection of Muscularis propria Invasion in Urothelial Carcinoma Using Artificial Intelligence
Conclusion: The algorithm we developed may greatly aid in accurate identification of muscularis propria invasion by imitating the thought process of the pathologist.PMID:38803309 | DOI:10.1177/15330338241257479 (Source: Cell Research)
Source: Cell Research - May 28, 2024 Category: Cytology Authors: Ibrahim Fahoum Rabab Naamneh Keren Silberberg Rami Hagege Dov Hershkovitz Source Type: research
