Limitations of the Commercially Available Gene Expression Test in Predicting Cutaneous Squamous Cell Carcinoma Metastasis and Clinical Outcomes
Clinical genetic tests are integral to healthcare decision-making. However, the unclear regulatory framework, especially regarding products that evade stringent FDA oversight, may compromise test validity and transparency. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - May 15, 2024 Category: Dermatology Authors: Joel L. Sax, Christopher D. McFarland, Bryan T. Carroll Source Type: research
Predicting Survival Using Whole-Liver MRI Radiomics in Patients with Hepatocellular Carcinoma After TACE Refractoriness
ConclusionThe combined radiomics model from whole-liver signatures may effectively predict survival for HCC patients continuing TACE after TACE refractoriness. The TLrad-score and tumor burden are potential prognostic markers for TACE therapy following TACE-resistance.Graphical Abstract (Source: CardioVascular and Interventional Radiology)
Source: CardioVascular and Interventional Radiology - May 15, 2024 Category: Radiology Source Type: research
GPC3-targeted CAR-T cells expressing GLUT1 or AGK exhibit enhanced antitumor activity against hepatocellular carcinoma
Acta Pharmacologica Sinica, Published online: 15 May 2024; doi:10.1038/s41401-024-01287-8GPC3-targeted CAR-T cells expressing GLUT1 or AGK exhibit enhanced antitumor activity against hepatocellular carcinoma (Source: Acta Pharmacologica Sinica)
Source: Acta Pharmacologica Sinica - May 15, 2024 Category: Drugs & Pharmacology Authors: Rui-xin Sun Yi-fan Liu Yan-sha Sun Min Zhou Yi Wang Bi-zhi Shi Hua Jiang Zong-hai Li Source Type: research
Conversion Surgery for Patients With Low-Risk Papillary Thyroid Carcinoma
This cohort study examines the surgical, pathologic, and oncologic outcomes of patients with low-risk papillary thyroid carcinoma who underwent conversion surgery after a period of active surveillance. (Source: JAMA Otolaryngology - Head and Neck Surgery)
Source: JAMA Otolaryngology - Head and Neck Surgery - May 15, 2024 Category: ENT & OMF Source Type: research
Long Non-coding RNA PCED1B Antisense RNA 1 Promotes Cell Proliferation and Invasion in Hepatocellular Carcinoma by Regulating the MicroRNA-34a/CD44 Axis
ConclusionPCED1B-AS1 may play an oncogenic role by regulating the miR-34a/CD44 axis in HCC. (Source: Journal of Huazhong University of Science and Technology -- Medical Sciences --)
Source: Journal of Huazhong University of Science and Technology -- Medical Sciences -- - May 15, 2024 Category: Research Source Type: research
