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Outcomes of Immediate Total Thyroidectomy in First-Side Loss of Neuromonitoring Signal
This cohort study of patients planning to undergo total thyroidectomy compares outcomes for bilateral surgery with staged surgery in cases where loss of signal occurred following removal of the first side. (Source: JAMA Otolaryngology - Head and Neck Surgery)
Source: JAMA Otolaryngology - Head and Neck Surgery - April 25, 2024 Category: ENT & OMF Source Type: research

Neighborhood-Level Disadvantage and Delayed Adjuvant Therapy in Head and Neck Cancer
This multicenter cohort study examines if living in a socioeconomically disadvantaged neighborhood is associated with an increased likelihood of delays in initiating guideline-adherent adjuvant radiation therapy among patients with head and neck cancer. (Source: JAMA Otolaryngology - Head and Neck Surgery)
Source: JAMA Otolaryngology - Head and Neck Surgery - April 25, 2024 Category: ENT & OMF Source Type: research

Severe Hypoplasia of Paranasal Sinuses and Turbinates
This case report describes a patient in their 40s with a history of bronchiectasis, azoospermia, and epididymal cysts presented with bilateral nasal obstruction. (Source: JAMA Otolaryngology - Head and Neck Surgery)
Source: JAMA Otolaryngology - Head and Neck Surgery - April 25, 2024 Category: ENT & OMF Source Type: research

ctHPVDNA in Patients With HPV-Associated Head and Neck Cancer After Surgery
This cohort study examines the association of posttreatment circulating tumor human papillomavirus DNA (ctHPVDNA) with residual disease and 2-year overall survival and recurrence-free survival in patients with HPV-associated head and neck cancer. (Source: JAMA Otolaryngology - Head and Neck Surgery)
Source: JAMA Otolaryngology - Head and Neck Surgery - April 25, 2024 Category: ENT & OMF Source Type: research

Progressive Cheek Swelling in an Older Woman
An 87-year-old woman presents with sudden-onset worsening right facial swelling and pain and generalized maxillary alveolar hyperplasia. What is your diagnosis? (Source: JAMA Otolaryngology - Head and Neck Surgery)
Source: JAMA Otolaryngology - Head and Neck Surgery - April 25, 2024 Category: ENT & OMF Source Type: research

AI Hallucination
This essay reports on fictitious source materials created by AI chatbots, encourages human oversight to identify fabricated information, and suggests a creative use for these tools. (Source: JAMA Otolaryngology - Head and Neck Surgery)
Source: JAMA Otolaryngology - Head and Neck Surgery - April 18, 2024 Category: ENT & OMF Source Type: research

My Favorite Sinus
This essay reflects on the author ’s approach to interviewing applicants for medical residency in the otolaryngology department. (Source: JAMA Otolaryngology - Head and Neck Surgery)
Source: JAMA Otolaryngology - Head and Neck Surgery - April 18, 2024 Category: ENT & OMF Source Type: research

Reconstruction for Salvage Laryngectomy With Limited Pharyngectomy
This cohort study examines whether the closure technique of salvage laryngectomy is associated with early postoperative and long-term functional outcomes. (Source: JAMA Otolaryngology - Head and Neck Surgery)
Source: JAMA Otolaryngology - Head and Neck Surgery - April 18, 2024 Category: ENT & OMF Source Type: research

Skip Polysomnography Before Adenotonsillectomy for Snoring? —Reply
In Reply We thank Kaditis et al for bringing attention to the insights and clinical complexities illuminated by the results of the Pediatric Adenotonsillectomy Trial for Snoring (PATS), as published in JAMA and JAMA Otolaryngology –Head& Neck Surgery. As elucidated by the authors, PATS introduced the term mild sleep-disordered breathing (SDB) to encompass children with both primary snoring (AHI,<1) and mild obstructive sleep apnea (OSA) (apnea-hypopnea index [AHI], 1-3), distinct from the conventional definition of mild OSA typically denoted by an AHI of 1 to 5. It is noteworthy that all participants in PATS under...
Source: JAMA Otolaryngology - Head and Neck Surgery - April 18, 2024 Category: ENT & OMF Source Type: research

Skip Polysomnography Before Adenotonsillectomy for Snoring?
To the Editor In December 2023, results of the Pediatric Adenotonsillectomy Trial for Snoring (PATS) were published in JAMA and JAMA Otolaryngology –Head& Neck Surgery. Like other elegantly designed and executed clinical trials, PATS triggers more questions than the answers provided. The novel term mild sleep-disordered breathing (SDB) is introduced that combines snoring with an apnea-hypopnea index (AHI) of less than 1 event/h (primary snoring) and AHI 1 to less than 3 events/h (mild obstructive sleep apnea [OSA]). Although both subgroups are indistinguishable regarding symptoms and morbidity, this term could confus...
Source: JAMA Otolaryngology - Head and Neck Surgery - April 18, 2024 Category: ENT & OMF Source Type: research

Considerations in Salvage Laryngectomy Reconstruction
Pharyngocutaneous fistula (PCF) is a dreaded complication from total laryngectomy (TL), as it can cause wound issues, lengthen hospitalization, increase costs, and prolong nothing-by-mouth status. In this issue of JAMA Otolaryngology –Head& Neck Surgery, Moreno et al evaluated 309 patients from multiple institutions who underwent salvage TL. This work nicely focuses on the subset of TL with limited pharyngeal defect amenable to primary closure (PC), distinguishing it from other work on this topic. The authors report a PCF rate of 29%. In their study, the investigators evaluated the use of free tissue transfer (FTT) v...
Source: JAMA Otolaryngology - Head and Neck Surgery - April 18, 2024 Category: ENT & OMF Source Type: research

Addressing Financial Toxicity in Head and Neck Cancer
This Viewpoint calls for consideration of the financial costs of head and neck cancer care when choosing treatment strategies for patients who may face severe financial stress or insolvency due to cancer treatment. (Source: JAMA Otolaryngology - Head and Neck Surgery)
Source: JAMA Otolaryngology - Head and Neck Surgery - April 11, 2024 Category: ENT & OMF Source Type: research

TORS and Radiation Volume in Unknown Primary Squamous Cell Carcinoma of the Neck
This phase 2 trial assesses whether transoral robotic surgery and tailored radiotherapy are associated with favorable outcomes among patients with unknown primary squamous cell carcinoma. (Source: JAMA Otolaryngology - Head and Neck Surgery)
Source: JAMA Otolaryngology - Head and Neck Surgery - April 11, 2024 Category: ENT & OMF Source Type: research

Neoadjuvant Chemotherapy and Transoral Robotic Surgery for Oropharynx Cancer and Quality of Life —Reply
In Reply In reaction to our recent report on quality-of-life outcomes following neoadjuvant chemotherapy and transoral robotic surgery (NECTORS) for human papillomavirus virus –associated oropharyngeal squamous cell carcinoma (HPV-OPSCC), Granell and Gutierrez-Fonseca have raised concerns to which we would like to respond. (Source: JAMA Otolaryngology - Head and Neck Surgery)
Source: JAMA Otolaryngology - Head and Neck Surgery - April 11, 2024 Category: ENT & OMF Source Type: research

Complete Clinical Response With Pembrolizumab for Cutaneous Squamous Cell Carcinoma
This case report describes an 89-year-old patient with prior cutaneous squamous cell carcinoma who presented with a new isolated metastasis and was subsequently treated with pembrolizumab, which produced a complete clinical response. (Source: JAMA Otolaryngology - Head and Neck Surgery)
Source: JAMA Otolaryngology - Head and Neck Surgery - April 11, 2024 Category: ENT & OMF Source Type: research