Diagnostic performance of < sup > 18 < /sup > F ‑DCFPyL PET vs. < sup > 68 < /sup > Ga ‑PSMA PET/CT in patients with suspected prostate cancer: A systemic review and meta‑analysis
In conclusion, a comparable diagnostic performance for patients with suspected PCa was determined for 18F-DCFPyL PET and 68Ga-PSMA PET/CT. However, it is crucial to keep in mind that the findings of the present meta-analysis come from investigations with modest sample sizes. Therefore, more extensive research is required to obtain more solid data.PMID:38486944 | PMC:PMC10938285 | DOI:10.3892/ol.2024.14321 (Source: Oncology Letters)
Source: Oncology Letters - March 15, 2024 Category: Cancer & Oncology Authors: Zhibing Jiang Jinjing Guo Liang Hu Siyu Yang Bin Meng Qun Tang Source Type: research

Adrenal ganglioneuroblastoma with metastasis near the renal hilum in an adult female: A case report and review of the literature
Oncol Lett. 2024 Feb 29;27(4):187. doi: 10.3892/ol.2024.14319. eCollection 2024 Apr.ABSTRACTGanglioneuroblastoma (GNB), predominantly observed in children, is an uncommon malignant tumor in adults, with established treatment protocols notably lacking. The present study details the case of a 20-year-old woman who presented with a left adrenal gland mass, identified during a physical examination. Additionally, an unidentified mass was noted near the renal hilum in the preoperative evaluation. Following thorough preoperative preparation, both the primary adrenal gland mass and the renal hilar mass were surgically removed. The...
Source: Oncology Letters - March 15, 2024 Category: Cancer & Oncology Authors: Xinzhang Zhang Yiwen Zhang Dan Peng Xin Shi Zhuorui Zhang Junfeng Wang Xue Zhang Jinjun Leng Wei Li Source Type: research

Diagnostic performance of < sup > 18 < /sup > F ‑DCFPyL PET vs. < sup > 68 < /sup > Ga ‑PSMA PET/CT in patients with suspected prostate cancer: A systemic review and meta‑analysis
In conclusion, a comparable diagnostic performance for patients with suspected PCa was determined for 18F-DCFPyL PET and 68Ga-PSMA PET/CT. However, it is crucial to keep in mind that the findings of the present meta-analysis come from investigations with modest sample sizes. Therefore, more extensive research is required to obtain more solid data.PMID:38486944 | PMC:PMC10938285 | DOI:10.3892/ol.2024.14321 (Source: Oncology Letters)
Source: Oncology Letters - March 15, 2024 Category: Cancer & Oncology Authors: Zhibing Jiang Jinjing Guo Liang Hu Siyu Yang Bin Meng Qun Tang Source Type: research

Adrenal ganglioneuroblastoma with metastasis near the renal hilum in an adult female: A case report and review of the literature
Oncol Lett. 2024 Feb 29;27(4):187. doi: 10.3892/ol.2024.14319. eCollection 2024 Apr.ABSTRACTGanglioneuroblastoma (GNB), predominantly observed in children, is an uncommon malignant tumor in adults, with established treatment protocols notably lacking. The present study details the case of a 20-year-old woman who presented with a left adrenal gland mass, identified during a physical examination. Additionally, an unidentified mass was noted near the renal hilum in the preoperative evaluation. Following thorough preoperative preparation, both the primary adrenal gland mass and the renal hilar mass were surgically removed. The...
Source: Oncology Letters - March 15, 2024 Category: Cancer & Oncology Authors: Xinzhang Zhang Yiwen Zhang Dan Peng Xin Shi Zhuorui Zhang Junfeng Wang Xue Zhang Jinjun Leng Wei Li Source Type: research

Esophageal squamous cell carcinoma transformed into neuroendocrine carcinoma after neoadjuvant immunochemotherapy: A case report
In conclusion, histological transformation to ENEC is a potential mechanism of acquired resistance to ICIs in ESCC. Prospective larger studies are warranted to further characterize ESCC-to-NEC transformation on use of ICIs.PMID:38476207 | PMC:PMC10928968 | DOI:10.3892/ol.2024.14317 (Source: Oncology Letters)
Source: Oncology Letters - March 13, 2024 Category: Cancer & Oncology Authors: Gaojie Xin Naicheng Song Ke Jiang Source Type: research

Value of high ‑risk human papillomavirus detection combined with colposcopy in the diagnosis of cervical cancer and precancerous lesions
Oncol Lett. 2024 Feb 29;27(4):185. doi: 10.3892/ol.2024.14318. eCollection 2024 Apr.ABSTRACTIn the present study, the diagnostic value of high risk-human papillomavirus (HR-HPV) combined with colposcopy for the detection of cervical cancer and precancerous lesions was evaluated. A total of 397 patients with confirmed cervical disease were enrolled between August 2020 and December 2021. According to the pathological diagnosis, the patients were divided into cervical intraepithelial neoplasia grade I (CIN I; n=153 cases), CIN II (n=101 cases), CIN III (n=86 cases) and cervical cancer (n=57 cases) groups. The HR-HPV-positive ...
Source: Oncology Letters - March 13, 2024 Category: Cancer & Oncology Authors: Ping Wang Dongxia Gao Xiaoni Yu Gaoxiang Zhu Source Type: research

Unveiling the experimental proof of the anticancer potential of ginsenoside Rg3 (Review)
Oncol Lett. 2024 Feb 28;27(4):182. doi: 10.3892/ol.2024.14315. eCollection 2024 Apr.ABSTRACTGinsenoside Rg3 (GS-Rg3), a sterol molecule isolated from ginseng, has demonstrated various immunological properties, including inhibition of cancer cell proliferation and metastasis, reversal of drug resistance and enhancement of chemotherapy sensitivity. The recent surge in attention towards GS-Rg3 can be attributed to its potential as an antitumor angiogenesis agent and as a therapeutic candidate for immunotherapy. The development of GS-Rg3 as an agent for these purposes has accelerated research on its mechanisms of action. The p...
Source: Oncology Letters - March 13, 2024 Category: Cancer & Oncology Authors: Yongmin Liu Guanchu Li Jinyue Ning Yi Zhao Source Type: research

Spontaneous rupture ‑induced life‑threatening mediastinal mixed germ cell tumor: A case report and therapeutic considerations
Oncol Lett. 2024 Feb 28;27(4):183. doi: 10.3892/ol.2024.14316. eCollection 2024 Apr.ABSTRACTSpontaneous rupture and hemorrhage of mediastinal germ cell tumors is a rare occurrence. In the current report, the case of a 20-year-old male patient who was admitted with chest tightness and dyspnea is presented. An urgent chest CT scan revealed a large tumor in the right anterior mediastinum, measuring ~12 cm in diameter, with associated intratumoral hemorrhage. An emergency thoracotomy was performed to excise the lesion, which revealed that the bleeding was caused by a ruptured tumor. Postoperative pathological findings revealed...
Source: Oncology Letters - March 13, 2024 Category: Cancer & Oncology Authors: Xiaosong Li Shenghan Xu Yunbin Li Yanping Tang Kaiying Wang Yumeng Lei Jian Ma Jian Li Source Type: research

Esophageal squamous cell carcinoma transformed into neuroendocrine carcinoma after neoadjuvant immunochemotherapy: A case report
In conclusion, histological transformation to ENEC is a potential mechanism of acquired resistance to ICIs in ESCC. Prospective larger studies are warranted to further characterize ESCC-to-NEC transformation on use of ICIs.PMID:38476207 | PMC:PMC10928968 | DOI:10.3892/ol.2024.14317 (Source: Oncology Letters)
Source: Oncology Letters - March 13, 2024 Category: Cancer & Oncology Authors: Gaojie Xin Naicheng Song Ke Jiang Source Type: research

Value of high ‑risk human papillomavirus detection combined with colposcopy in the diagnosis of cervical cancer and precancerous lesions
Oncol Lett. 2024 Feb 29;27(4):185. doi: 10.3892/ol.2024.14318. eCollection 2024 Apr.ABSTRACTIn the present study, the diagnostic value of high risk-human papillomavirus (HR-HPV) combined with colposcopy for the detection of cervical cancer and precancerous lesions was evaluated. A total of 397 patients with confirmed cervical disease were enrolled between August 2020 and December 2021. According to the pathological diagnosis, the patients were divided into cervical intraepithelial neoplasia grade I (CIN I; n=153 cases), CIN II (n=101 cases), CIN III (n=86 cases) and cervical cancer (n=57 cases) groups. The HR-HPV-positive ...
Source: Oncology Letters - March 13, 2024 Category: Cancer & Oncology Authors: Ping Wang Dongxia Gao Xiaoni Yu Gaoxiang Zhu Source Type: research

Unveiling the experimental proof of the anticancer potential of ginsenoside Rg3 (Review)
Oncol Lett. 2024 Feb 28;27(4):182. doi: 10.3892/ol.2024.14315. eCollection 2024 Apr.ABSTRACTGinsenoside Rg3 (GS-Rg3), a sterol molecule isolated from ginseng, has demonstrated various immunological properties, including inhibition of cancer cell proliferation and metastasis, reversal of drug resistance and enhancement of chemotherapy sensitivity. The recent surge in attention towards GS-Rg3 can be attributed to its potential as an antitumor angiogenesis agent and as a therapeutic candidate for immunotherapy. The development of GS-Rg3 as an agent for these purposes has accelerated research on its mechanisms of action. The p...
Source: Oncology Letters - March 13, 2024 Category: Cancer & Oncology Authors: Yongmin Liu Guanchu Li Jinyue Ning Yi Zhao Source Type: research

Spontaneous rupture ‑induced life‑threatening mediastinal mixed germ cell tumor: A case report and therapeutic considerations
Oncol Lett. 2024 Feb 28;27(4):183. doi: 10.3892/ol.2024.14316. eCollection 2024 Apr.ABSTRACTSpontaneous rupture and hemorrhage of mediastinal germ cell tumors is a rare occurrence. In the current report, the case of a 20-year-old male patient who was admitted with chest tightness and dyspnea is presented. An urgent chest CT scan revealed a large tumor in the right anterior mediastinum, measuring ~12 cm in diameter, with associated intratumoral hemorrhage. An emergency thoracotomy was performed to excise the lesion, which revealed that the bleeding was caused by a ruptured tumor. Postoperative pathological findings revealed...
Source: Oncology Letters - March 13, 2024 Category: Cancer & Oncology Authors: Xiaosong Li Shenghan Xu Yunbin Li Yanping Tang Kaiying Wang Yumeng Lei Jian Ma Jian Li Source Type: research

Esophageal squamous cell carcinoma transformed into neuroendocrine carcinoma after neoadjuvant immunochemotherapy: A case report
In conclusion, histological transformation to ENEC is a potential mechanism of acquired resistance to ICIs in ESCC. Prospective larger studies are warranted to further characterize ESCC-to-NEC transformation on use of ICIs.PMID:38476207 | PMC:PMC10928968 | DOI:10.3892/ol.2024.14317 (Source: Oncology Letters)
Source: Oncology Letters - March 13, 2024 Category: Cancer & Oncology Authors: Gaojie Xin Naicheng Song Ke Jiang Source Type: research

Value of high ‑risk human papillomavirus detection combined with colposcopy in the diagnosis of cervical cancer and precancerous lesions
Oncol Lett. 2024 Feb 29;27(4):185. doi: 10.3892/ol.2024.14318. eCollection 2024 Apr.ABSTRACTIn the present study, the diagnostic value of high risk-human papillomavirus (HR-HPV) combined with colposcopy for the detection of cervical cancer and precancerous lesions was evaluated. A total of 397 patients with confirmed cervical disease were enrolled between August 2020 and December 2021. According to the pathological diagnosis, the patients were divided into cervical intraepithelial neoplasia grade I (CIN I; n=153 cases), CIN II (n=101 cases), CIN III (n=86 cases) and cervical cancer (n=57 cases) groups. The HR-HPV-positive ...
Source: Oncology Letters - March 13, 2024 Category: Cancer & Oncology Authors: Ping Wang Dongxia Gao Xiaoni Yu Gaoxiang Zhu Source Type: research

Unveiling the experimental proof of the anticancer potential of ginsenoside Rg3 (Review)
Oncol Lett. 2024 Feb 28;27(4):182. doi: 10.3892/ol.2024.14315. eCollection 2024 Apr.ABSTRACTGinsenoside Rg3 (GS-Rg3), a sterol molecule isolated from ginseng, has demonstrated various immunological properties, including inhibition of cancer cell proliferation and metastasis, reversal of drug resistance and enhancement of chemotherapy sensitivity. The recent surge in attention towards GS-Rg3 can be attributed to its potential as an antitumor angiogenesis agent and as a therapeutic candidate for immunotherapy. The development of GS-Rg3 as an agent for these purposes has accelerated research on its mechanisms of action. The p...
Source: Oncology Letters - March 13, 2024 Category: Cancer & Oncology Authors: Yongmin Liu Guanchu Li Jinyue Ning Yi Zhao Source Type: research