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Effects of ESPCS mode nursing on the surgical tolerance, gastrointestinal tract recovery and self ‑management efficacy of patients with colon cancer
Oncol Lett. 2024 Apr 3;27(6):247. doi: 10.3892/ol.2024.14380. eCollection 2024 Jun.ABSTRACTColon cancer is a common gastrointestinal malignant tumor. In addition to conventional treatment, thoughtful and comprehensive aftercare should be given to patients. The present study aimed to explore the effects of explain-simulate-practice-communication-support (ESPCS) model nursing on the surgical tolerance, gastrointestinal recovery and self-management efficacy of patients with colon cancer. The clinical data of 136 patients with colon cancer diagnosed and treated at the Second Affiliated Hospital of Harbin Medical University (Ha...
Source: Oncology Letters - April 19, 2024 Category: Cancer & Oncology Authors: Rui Yu Meiling Sun Shuli Xia Li Zhang Source Type: research

Daratumumab ‑resistant multiple myeloma with extramedullary disease successfully treated with combination elotuzumab, pomalidomide and dexamethasone: A case report
Oncol Lett. 2024 Apr 3;27(6):248. doi: 10.3892/ol.2024.14381. eCollection 2024 Jun.ABSTRACTDespite the emergence of monoclonal antibodies, the prognosis of patients with multiple myeloma (MM) with extramedullary disease remains poor. The present report describes a rare case of daratumumab-refractory MM that was successfully treated with elotuzumab, pomalidomide and dexamethasone. A 66-year-old male patient diagnosed with MM was treated with bortezomib, lenalidomide and dexamethasone, followed by high-dose chemotherapy and autologous stem cell transplantation. Thereafter, the patient was treated with lenalidomide and dexame...
Source: Oncology Letters - April 19, 2024 Category: Cancer & Oncology Authors: Masataka Sakashita Naohi Sahara Jun Aoki Takashi Matsunaga Seiichiro Kobayashi Shinsuke Kitahara Tomoki Fujii Nobuhiro Ohno Source Type: research

Metastasis to the bladder from primary breast cancer: A case report and literature review
Oncol Lett. 2024 Apr 5;27(6):249. doi: 10.3892/ol.2024.14382. eCollection 2024 Jun.ABSTRACTBreast cancer is the most prevalent malignant tumor affecting women and represents the leading cause of female cancer-related mortality worldwide. Although distant organ metastasis accounts for the majority of breast cancer-related deaths, reports on bladder metastasis are limited in the existing literature. The present study describes the case of a patient with bladder metastasis originating from breast cancer. In addition, the present study also provides a review of 54 cases of similar disease that have been documented in the curre...
Source: Oncology Letters - April 19, 2024 Category: Cancer & Oncology Authors: Hanli Zhou Danna Liu Lu Chen Yujie Zhang Xiaoli Zhao Yongchao Ge Mengmeng Liu Tiandong Kong Source Type: research

Identification and validation of PCDHGA12 and PRRX1 methylation for detecting lung cancer in bronchial washing sample
In conclusion, the present study showed that the regulatory regions of PCDHGA12 and PRRX1 are highly methylated in LC and can be used to detect LC in BW specimens as a diagnostic adjunct to cytology in clinical practice.PMID:38638845 | PMC:PMC11024764 | DOI:10.3892/ol.2024.14379 (Source: Oncology Letters)
Source: Oncology Letters - April 19, 2024 Category: Cancer & Oncology Authors: Tae Jeong Oh Seunghyun Jang Su Ji Kim Min A Woo Ji Woong Son In Beom Jeong Min Hyeok Lee Sungwhan An Source Type: research

Erratum: [Corrigendum] miR ‑137 suppresses proliferation, migration and invasion of colon cancer cell lines by targeting TCF4
Oncol Lett. 2024 Apr 3;27(6):245. doi: 10.3892/ol.2024.14378. eCollection 2024 Jun.ABSTRACT[This corrects the article DOI: 10.3892/ol.2018.8364.].PMID:38638846 | PMC:PMC11024761 | DOI:10.3892/ol.2024.14378 (Source: Oncology Letters)
Source: Oncology Letters - April 19, 2024 Category: Cancer & Oncology Authors: Wei-Ping Bi Min Xia Xin-Jian Wang Source Type: research

Effects of combined use of ribociclib with PARP1 inhibitor on cell kinetics in breast cancer
In conclusion, the results obtained from cell kinetics parameters demonstrated the anticancer and antiproliferative effects of the combination of VLM and DPQ on breast cancer cells.PMID:38638847 | PMC:PMC11024784 | DOI:10.3892/ol.2024.14376 (Source: Oncology Letters)
Source: Oncology Letters - April 19, 2024 Category: Cancer & Oncology Authors: Ercan Pulat Mehmet R Top çul Source Type: research

[Retracted] Tremella polysaccharides inhibit cellular apoptosis and autophagy induced by Pseudomonas aeruginosa lipopolysaccharide in A549 cells through sirtuin 1 activation
Oncol Lett. 2024 Apr 8;27(6):251. doi: 10.3892/ol.2024.14384. eCollection 2024 Jun.ABSTRACT[This retracts the article DOI: 10.3892/ol.2018.8554.].PMID:38638848 | PMC:PMC11024760 | DOI:10.3892/ol.2024.14384 (Source: Oncology Letters)
Source: Oncology Letters - April 19, 2024 Category: Cancer & Oncology Authors: Xiaolan Shi Wenfeng Wei Ning Wang Source Type: research

Oncolytic virotherapy stimulates anti ‑tumor immune response and demonstrates activity in advanced sarcoma: Report of two cases
Oncol Lett. 2024 Apr 3;27(6):244. doi: 10.3892/ol.2024.14377. eCollection 2024 Jun.ABSTRACTSarcoma is derived from mesenchymal neoplasms and has numerous subtypes, accounting for 1% of all adult malignancies and 15% of childhood malignancies. The prognosis of metastatic or recurrent sarcoma remains poor. The current study presents two cases of sarcoma enrolled in a phase I dose escalation trial for solid tumor, who had previously failed all standard therapies. These patients were treated with VG161, an immune-stimulating herpes simplex virus type 1 oncolytic virus with payloads of IL-12, IL-15 and IL-15 receptor α unit, a...
Source: Oncology Letters - April 19, 2024 Category: Cancer & Oncology Authors: Yeting Qiu Aijun Qin Ronghua Zhao Jun Ding William Wei-Guo Jia Manu Singh Yanal Murad Qian Tan Ganessan Kichenadasse Source Type: research

Early growth response 1 regulates dual ‑specificity protein phosphatase 1 and inhibits cell migration and invasion of tongue squamous cell carcinoma
In conclusion, the present study demonstrated that Egr-1 regulates TSCC cell migration and invasion through modulating DUSP1, suggesting the potential of Egr-1 and DUSP1 as therapy targets for TSCC.PMID:38623570 | PMC:PMC11017821 | DOI:10.3892/ol.2024.14373 (Source: Oncology Letters)
Source: Oncology Letters - April 16, 2024 Category: Cancer & Oncology Authors: Longxun Zhou Yuqun Shan Jun Li Min Li Zhen Meng Na Guo Source Type: research

[Retracted] Downregulation of long non ‑coding RNA GAS5 promotes cell proliferation, migration and invasion in esophageal squamous cell carcinoma
Oncol Lett. 2024 Apr 2;27(6):239. doi: 10.3892/ol.2024.14372. eCollection 2024 Jun.ABSTRACT[This retracts the article DOI: 10.3892/ol.2018.8797.].PMID:38623571 | PMC:PMC11017816 | DOI:10.3892/ol.2024.14372 (Source: Oncology Letters)
Source: Oncology Letters - April 16, 2024 Category: Cancer & Oncology Authors: Ke Ke Zhanwen Sun Zhengjun Wang Source Type: research

Efficacy of consolidation of immune checkpoint inhibitor after chemoradiation for unresectable, locally advanced PD ‑L1 negative non‑small cell lung cancer: A systematic review and meta‑analysis
Oncol Lett. 2024 Apr 3;27(6):242. doi: 10.3892/ol.2024.14375. eCollection 2024 Jun.ABSTRACTChemoradiotherapy (CRT) followed by consolidation of immune checkpoint inhibitors (ICIs), such as durvalumab or pembrolizumab, for patients with unresectable, locally advanced non-small cell lung cancer (NSCLC) with tumor PD-L1 expression <1% remains a topic of controversy. Previous studies from PubMed, Cochrane Library and Embase databases were searched for a meta-analysis. A total of 16 studies were included in part one of the meta-analysis and it was observed that consolidation of ICIs after CRT improved overall survival (OS) [...
Source: Oncology Letters - April 15, 2024 Category: Cancer & Oncology Authors: Sunyin Rao Li Min Jie Zhao Juan Su Lianhua Ye Source Type: research