Induction of Trained Immunity using β-glucan and its protective responses in Nile tilapia, Oreochromis niloticus
Dev Comp Immunol. 2024 Apr 25:105188. doi: 10.1016/j.dci.2024.105188. Online ahead of print.ABSTRACTEmerging and re-emerging diseases in fish cause drastic economic losses in the aquaculture sector. To combat the impact of disease outbreaks and prevent the emergence of infections in culture systems, understanding the advanced strategies for protecting fish against infections is inevitable in fish health research. Therefore, the present study aimed to evaluate the induction of trained immunity and its protective efficacy against Streptococcus agalactiae in tilapia. For this, Nile tilapia and the primary head kidney macropha...
Source: Developmental and Comparative Immunology - April 27, 2024 Category: Allergy & Immunology Authors: David Waikhom Jeena Kezhedath Sooraj Nediyirippil Suresh Megha Kadam Bedekar Tincy Varghese Pani Prasad Kurcheti Rajendran Kooloth Valappil Source Type: research
How could our genetics impact COVID-19 vaccine response?
Expert Rev Clin Immunol. 2024 Apr 27:1-13. doi: 10.1080/1744666X.2024.2346584. Online ahead of print.ABSTRACTINTRODUCTION: The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has posed unprecedented global health challenges since its emergence in December 2019. The rapid availability of vaccines has been estimated to save millions of lives, but there is variation in how individuals respond to vaccines, influencing their effectiveness at an individual, and population level.AREAS COVERED: This review focuses on human genetic factors influencing the immune response and effectiveness of vaccines, highlighting the importance...
Source: Expert Review of Clinical Immunology - April 27, 2024 Category: Allergy & Immunology Authors: Keyi Zheng Amanda Y Chong Alexander J Mentzer Source Type: research
Cracking the Code: Investigating the Correlation between Aerobic Vaginitis and Preterm Labor
Medicina (Kaunas). 2024 Apr 18;60(4):648. doi: 10.3390/medicina60040648.ABSTRACTAerobic vaginitis (AV) is a distinct clinical entity characterized by inflammation and abnormal vaginal microflora. Often mistaken for bacterial vaginosis, AV remains relatively unknown and underdiagnosed. AV's understanding is evolving, with some experts suggesting it may primarily be an immunological disorder, the prevalence of which has a range of 7-13% in non-pregnant women and 4.1-8.3% during pregnancy. Pregnancy can affect susceptibility to vaginal infections, leading to adverse outcomes for the woman and the newborn. This review summariz...
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Panagiota Zarmakoupi Alexandros Psarris Christina Karasmani Panagiotis Antsaklis Marianna Theodora Michael Syndos Andreas Pampanos Kalliopi I Pappa Ekaterini Domali Nikolaos Thomakos Karolina Akinosoglou Aristotelis Tsiakalos George Daskalakis Source Type: research
Evaluation of Toll-Like Receptor Gene Expressions in Encephalitozoon intestinalis Infection
In conclusion, this study is the f irst report in which the changes in ten different TLR gene expressions were evaluated at different times in MDCK cells stimulated with E.intestinalis and the change in TLR3 gene expression.PMID:38676584 | DOI:10.5578/mb.202498201 (Source: Mikrobiyoloji Bulteni)
Source: Mikrobiyoloji Bulteni - April 27, 2024 Category: Microbiology Authors: Erdi Uzun Ülfet Çetinkaya Source Type: research
Induction of Trained Immunity using β-glucan and its protective responses in Nile tilapia, Oreochromis niloticus
Dev Comp Immunol. 2024 Apr 25:105188. doi: 10.1016/j.dci.2024.105188. Online ahead of print.ABSTRACTEmerging and re-emerging diseases in fish cause drastic economic losses in the aquaculture sector. To combat the impact of disease outbreaks and prevent the emergence of infections in culture systems, understanding the advanced strategies for protecting fish against infections is inevitable in fish health research. Therefore, the present study aimed to evaluate the induction of trained immunity and its protective efficacy against Streptococcus agalactiae in tilapia. For this, Nile tilapia and the primary head kidney macropha...
Source: Developmental and Comparative Immunology - April 27, 2024 Category: Allergy & Immunology Authors: David Waikhom Jeena Kezhedath Sooraj Nediyirippil Suresh Megha Kadam Bedekar Tincy Varghese Pani Prasad Kurcheti Rajendran Kooloth Valappil Source Type: research
IUIS 2023: yEFIS workshop on career development and code-switching
Eur J Immunol. 2024 Apr 27:e2451155. doi: 10.1002/eji.202451155. Online ahead of print.NO ABSTRACTPMID:38676471 | DOI:10.1002/eji.202451155 (Source: European Journal of Immunology)
Source: European Journal of Immunology - April 27, 2024 Category: Allergy & Immunology Authors: Rosalie W M Kempkes Christos Nikolaou Myriam Nabhan Nathaniel Edward Bennett Saidu Source Type: research
Immune Checkpoint molecules in solid organ transplantation: a promising way to prevent rejection
Immunol Lett. 2024 Apr 25:106860. doi: 10.1016/j.imlet.2024.106860. Online ahead of print.ABSTRACTImmune checkpoint (IC) molecules modulate immune responses upon antigen presentation; the interaction between different IC molecules will result in the stimulation or, rather, the thwarting of such responses. Tumor cells express increased amounts of inhibitory IC molecules in an attempt to evade immune responses; therapeutic agents have been developed that bind inhibitory IC molecules, restoring tumor-directed immune responses and changing the prognosis of a number of cancers. Stimulation of inhibitory IC molecules could be be...
Source: Immunology Letters - April 27, 2024 Category: Allergy & Immunology Authors: Ilaria Righi Daria Trabattoni Lorenzo Rosso Valentina Vaira Mario Clerici Source Type: research
How could our genetics impact COVID-19 vaccine response?
Expert Rev Clin Immunol. 2024 Apr 27:1-13. doi: 10.1080/1744666X.2024.2346584. Online ahead of print.ABSTRACTINTRODUCTION: The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has posed unprecedented global health challenges since its emergence in December 2019. The rapid availability of vaccines has been estimated to save millions of lives, but there is variation in how individuals respond to vaccines, influencing their effectiveness at an individual, and population level.AREAS COVERED: This review focuses on human genetic factors influencing the immune response and effectiveness of vaccines, highlighting the importance...
Source: Expert Review of Clinical Immunology - April 27, 2024 Category: Allergy & Immunology Authors: Keyi Zheng Amanda Y Chong Alexander J Mentzer Source Type: research
Evaluation of Toll-Like Receptor Gene Expressions in Encephalitozoon intestinalis Infection
In conclusion, this study is the f irst report in which the changes in ten different TLR gene expressions were evaluated at different times in MDCK cells stimulated with E.intestinalis and the change in TLR3 gene expression.PMID:38676584 | DOI:10.5578/mb.202498201 (Source: Mikrobiyoloji Bulteni)
Source: Mikrobiyoloji Bulteni - April 27, 2024 Category: Microbiology Authors: Erdi Uzun Ülfet Çetinkaya Source Type: research
Cracking the Code: Investigating the Correlation between Aerobic Vaginitis and Preterm Labor
Medicina (Kaunas). 2024 Apr 18;60(4):648. doi: 10.3390/medicina60040648.ABSTRACTAerobic vaginitis (AV) is a distinct clinical entity characterized by inflammation and abnormal vaginal microflora. Often mistaken for bacterial vaginosis, AV remains relatively unknown and underdiagnosed. AV's understanding is evolving, with some experts suggesting it may primarily be an immunological disorder, the prevalence of which has a range of 7-13% in non-pregnant women and 4.1-8.3% during pregnancy. Pregnancy can affect susceptibility to vaginal infections, leading to adverse outcomes for the woman and the newborn. This review summariz...
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Panagiota Zarmakoupi Alexandros Psarris Christina Karasmani Panagiotis Antsaklis Marianna Theodora Michael Syndos Andreas Pampanos Kalliopi I Pappa Ekaterini Domali Nikolaos Thomakos Karolina Akinosoglou Aristotelis Tsiakalos George Daskalakis Source Type: research
The role of religion and COVID-19 vaccine uptake in England
CONCLUSION: This research indicates a potential influence of religious affiliation on vaccine uptake, highlighting the need for more carefully-tailored public health programmes. Recognizing the diverse associations of different religious affiliations on health behaviour is important for shaping future vaccination campaigns and policy interventions. Engaging with religious communities and leaders may be one method through which to deal with vaccine hesitancy and improve public health.PMID:38677793 | DOI:10.1016/j.vaccine.2024.04.006 (Source: Vaccine)
Source: Vaccine - April 27, 2024 Category: Allergy & Immunology Authors: Martin Ejnar Hansen Steven David Pickering Source Type: research
Post-marketing surveillance of 10,392 herpes zoster vaccines doses in Australia
CONCLUSIONS: While rates of AEFIs was higher with HZ/su than ZVL, most AEFIs were mild and did not require medical attention. Our findings support the change in vaccine recommendations and the use of HZ/su in immunisation programs.PMID:38677792 | DOI:10.1016/j.vaccine.2024.03.066 (Source: Vaccine)
Source: Vaccine - April 27, 2024 Category: Allergy & Immunology Authors: Ramona Muttucumaru Colleen L Lau Alan Leeb Deborah J Mills Nicholas Wood Luis Furuya-Kanamori Source Type: research
Corrigendum to "IMM-H004 protects against oxygen-glucose deprivation/reperfusion injury to BV2 microglia partly by modulating CKLF1 involved in microglia polarization" [Int. Immunopharmacol. 70 (2019) 69-79]
Int Immunopharmacol. 2024 Apr 26:112154. doi: 10.1016/j.intimp.2024.112154. Online ahead of print.NO ABSTRACTPMID:38677937 | DOI:10.1016/j.intimp.2024.112154 (Source: International Immunopharmacology)
Source: International Immunopharmacology - April 27, 2024 Category: Allergy & Immunology Authors: Chen Chen Qi-Di Ai Shi-Feng Chu Zhao Zhang Xin Zhou Piao Luo Ying-Jiao Liu Nai-Hong Chen Source Type: research
CD300e: Emerging role and mechanism as an immune-activating receptor
Int Immunopharmacol. 2024 Apr 26;133:112055. doi: 10.1016/j.intimp.2024.112055. Online ahead of print.ABSTRACTAs a transmembrane protein, CD300e is primarily expressed in myeloid cells. It belongs to the CD300 glycoprotein family, functioning as an immune-activating receptor. Dysfunction of CD300e has been suggested in many diseases, such as infections, immune disorders, obesity, and diabetes, signifying its potential as a key biomarker for disease diagnosis and treatment. This review is aimed to explore the roles and potential mechanisms of CD300e in regulating oxidative stress, immune cell activation, tissue damage and r...
Source: International Immunopharmacology - April 27, 2024 Category: Allergy & Immunology Authors: Na Liu Wenchang Sun Weixing Gao Shushan Yan Chunjuan Yang Jin Zhang Biao Ni Lili Zhang Jie Zang Sue Zhang Donghua Xu Source Type: research
The angelica Polysaccharide: a review of phytochemistry, pharmacology and beneficial effects on systemic diseases
Int Immunopharmacol. 2024 Apr 26;133:112025. doi: 10.1016/j.intimp.2024.112025. Online ahead of print.ABSTRACTAngelica sinensis is a perennial herb widely distributed around the world, and angelica polysaccharide (APS) is a polysaccharide extracted from Angelica sinensis. APS is one of the main active components of Angelica sinensis. A large number of studies have shown that APS has hematopoietic, promoting blood circulation, radiation resistance, lowering blood glucose, enhancing the body immunity and other pharmacological effects in a variety of diseases. However, different extraction methods and extraction sites greatly...
Source: International Immunopharmacology - April 27, 2024 Category: Allergy & Immunology Authors: Jie Shen Huan Qin Kangkang Li Huiqing Ding Xuehong Chen Meiyu Peng Xin Jiang Yantao Han Source Type: research
