Kuan-Teh Jeang Memorial Lecture: The broad impact of innate immune receptors in viral infection, cancer and autoimmunity
Jenny Pan-Yun Ting is a Taiwanese-American immunologist and microbiologist at University of North Carolina. She is a highly cited researcher who studies the role of NLR genes in regulating inflammation and how nanoparticles and microparticles can be used as vaccine adjuvants. In memory of Kuan-Teh Jeang, the lecture will discuss the roles ofmultiple innate immune receptors in viral infection in mouse models and patients. Theseminar will also describe the unexpected intrinsic roles of these receptors in adaptive Tand B lymphocytes. The latter adects both cancer and autoimmunity, with implications forimmunotherapeutics.For m...
Source: Videocast - All Events - April 3, 2024 Category: General Medicine Tags: Upcoming Events Source Type: video

IIG Seminar - Neuronal Control of Cutaneous Inflammation
Daniel H. Kaplan, MD, PhD is a Professor within the Department of Dermatology and Immunology, University of Pittsburgh. His laboratory is currently focused on understanding how intracellular communication mechanisms between immune cells and non-hematopoietic cells in the skin modulate cutaneous immunity and skin disease. The upcoming seminar will focus on the unique contributions of individual subsets of peripheral sensory neurons to the maintenance of cutaneous homeostasis and the development of inflammation.Air date: 4/17/2024 4:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - March 18, 2024 Category: General Medicine Tags: Upcoming Events Source Type: video

HIV Structural Biology Meeting
The National Institute for Allergy and Infectious Diseases will host the annual HIV Structural Biology Meeting Monday, June 24th and Tuesday, June 25th, 2024 at the NIH Natcher Conference Center in Bethesda, MD. The meeting will feature presentations from the Centers for HIV Structural Biology program, invited lectures and short talks selected from submitted abstracts. Poster sessions will be held each day to encourage networking and collaboration among HIV Cellular, Molecular and Structural Biologists. The meeting is expected to attract over 300 participants from the extramural and intramural research community.Air date: ...
Source: Videocast - All Events - March 7, 2024 Category: General Medicine Tags: Upcoming Events Source Type: video

HIV Structural Biology Meeting
The National Institute for Allergy and Infectious Diseases will host the annual HIV Structural Biology Meeting Monday, June 24th and Tuesday, June 25th, 2024 at the NIH Natcher Conference Center in Bethesda, MD. The meeting will feature presentations from the Centers for HIV Structural Biology program, invited lectures and short talks selected from submitted abstracts. Poster sessions will be held each day to encourage networking and collaboration among HIV Cellular, Molecular and Structural Biologists. The meeting is expected to attract over 300 participants from the extramural and intramural research community.Air date: ...
Source: Videocast - All Events - March 7, 2024 Category: General Medicine Tags: Upcoming Events Source Type: video

IIG Seminar - A neuro-immune circuit regulates nocturnal oscillations in intestinal Tregs
Dr. Mucida received his undergraduate degree in biology, with an emphasis on biochemistry and immunology, from the Federal University of Minas Gerais in Brazil in 2000. He received his Ph.D. jointly from the University of S ã o Paulo and New York University in 2005. After postdoctoral studies at the La Jolla Institute from 2006 to 2010, he joined The Rockefeller University as Assistant Professor in 2010. In 2016, he was promoted to Associate Professor. In 2021 he was promoted to Professor, with tenure and nominated HHMI investigator. The Mucida lab studies how the immune system associated with intestinal mucosae can gener...
Source: Videocast - All Events - February 21, 2024 Category: General Medicine Tags: Upcoming Events Source Type: video

Microbiome, metabolites and mucosal immunity
Dr. Kathy McCoy is a Professor in the Department of Physiology and Pharmacology, Cumming School of Medicine, member of the Snyder Institute, Scientific Director of the International Microbiome Center, and holds the Killam Memorial Chair at the University of Calgary, Canada. Her research group uses germ-free and gnotobiotic models to investigate the cellular and molecular mechanisms by which the microbiome regulates host immunity and physiology. She is particularly interested in the dynamic interplay between the gut microbiota and the innate and adaptive immune systems. Her research aims to understand how exposure to intest...
Source: Videocast - All Events - February 16, 2024 Category: General Medicine Tags: Upcoming Events Source Type: video

Understanding Immune Responses in Strongyloides stercoralis Infection: Implications for Bystander Effects on Tuberculosis and Type 2 Diabetes
Dr. Subash Babu is a distinguished physician-scientist with over two decades of expertise at the forefront of immunological research, particularly focusing on the intersection of infectious diseases and prevalent metabolic disorders in India. As the head of the NIAID-ICER laboratory in Chennai, his multidisciplinary approach is centered on helminth infections. His lab investigates protective immunity to filarial and Strongyloides stercoralis, offering insights crucial for vaccine development. Additionally, Dr. Babu explores the mechanisms underlying filarial lymphedema and the impact of helminth infections on tuberculosis ...
Source: Videocast - All Events - February 8, 2024 Category: General Medicine Tags: Upcoming Events Source Type: video

IIG Seminar - A new molecular regulatory pathway revealed by studying a human immunodysregulatory disorder
Our laboratory aims to elucidate molecular mechanisms regulating the human immune system and delineate how their derangements cause disease. As will be exemplified in the talk, our approach is to study patients with rare and poorly characterized inherited inborn errors of immunity who are followed at the NIH Clinical Center. By carefully investigating these “ experiments of nature ” we can draw inferences about molecular functions based on patient phenotypes. Our program broadly integrates the patients ’ clinical evaluations, assessments of their immune function, genetic and biochemical analyses to gain insights into...
Source: Videocast - All Events - February 2, 2024 Category: General Medicine Tags: Upcoming Events Source Type: video

Immunological mechanisms of mRNA vaccines- NIH FDA COVID-19 SIG Lecture Series
The production of antibodies (Abs) with high affinity and pathogen neutralization potential is crucial for preventing and fighting pathogen infection. To produce such Abs, na ï ve B cells are activated in response to cognate antigen and subsequently undergo rounds of somatic hypermutation and selection in germinal centers, specialized microanatomical sites in secondary lymphoid organs. This process of affinity maturation is tightly regulated by a specialized subset of CD4 T cells named T follicular helper (Tfh) cells. Our laboratory is interested in dissecting the complex biology of Tfh cells. Understanding (1) how Tfh di...
Source: Videocast - All Events - February 2, 2024 Category: General Medicine Tags: Upcoming Events Source Type: video

IIG Seminar: Harnessing Innate Immunity and Inflammasome Activation in Vaccines and Cancer Therapy
The IIG Seminar Series consists of invited speakers speaking on topics of great interest to the immunology community at the NIH and FDA. Each year, intramural and extramural speakers are chosen and invited by the IIG Steering Committee.Air date: 2/7/2024 4:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - January 18, 2024 Category: General Medicine Tags: Upcoming Events Source Type: video

Division of Allergy, Immunology and Transplantation Subcommittee
Report from Division Director and Division StaffAir date: 1/30/2024 1:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - January 12, 2024 Category: General Medicine Tags: Upcoming Events Source Type: video

Clinical Center Grand Rounds: Shaping The Early Life Gut Microbiome To Improve Future Health
Shaping The Early Life Gut Microbiome To Improve Future HealthSuchitra Hourigan, MDChief, Clinical Microbiome Unit Laboratory of Host Immunity and MicrobiomeNational Institute of Allergy and Infectious DiseasesFor more information go tohttps://clinicalcenter.nih.gov/about/news/grcurrent.htmlAir date: 1/31/2024 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - December 21, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

IIG Seminar - The gut-lung axis: how perturbation of the microbiome influences allergic airway inflammation
The microbiota plays an essential role in the education, development, and function of the immune system, both locally and systemically. Emerging experimental and epidemiological evidence highlights a cross-talk between the intestinal microbiota and the lungs, termed the ‘ gut – lung axis ’ . Changes in the constituents of the gut microbiome, through either diet, disease or medical interventions (such as early life antibiotics) is linked with altered immune responses and homeostasis in the airways. The importance of the gut – lung axis has become more evident following the identification of several gut microbe-deriv...
Source: Videocast - All Events - December 19, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

NIH FDA COVID-19 SIG Lecture Series- Michela Locci Ph.D.
The production of antibodies (Abs) with high affinity and pathogen neutralization potential is crucial for preventing and fighting pathogen infection. To produce such Abs, na ï ve B cells are activated in response to cognate antigen and subsequently undergo rounds of somatic hypermutation and selection in germinal centers, specialized microanatomical sites in secondary lymphoid organs. This process of affinity maturation is tightly regulated by a specialized subset of CD4 T cells named T follicular helper (Tfh) cells. Our laboratory is interested in dissecting the complex biology of Tfh cells. Understanding (1) how Tfh di...
Source: Videocast - All Events - December 4, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

Center for Excellence in HIV and Cancer Virology Fall Think Tank
The NCI's Center for Excellence in HIV and Cancer Virology Fall Think Tank is designed to facilitate the exchange of information about advances in the discovery, development, and delivery of antiviral and immunologic approaches for the prevention and treatment of HIV infection, AIDS-related malignancies, and cancer-associated viruses.Air date: 12/8/2023 8:30:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - November 22, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video