Exposure to Low Levels of Lead in Utero and Umbilical Cord Blood DNA Methylation in Project Viva: An Epigenome-Wide Association Study

Conclusion: Prenatal low-level lead exposure was associated with newborn DNA methylation, particularly in female infants. https://doi.org/10.1289/EHP1246 Received: 18 October 2016 Revised: 26 May 2017 Accepted: 13 June 2017 Published: 25 August 2017 Address correspondence to S. Wu, Dept. of Occupational and Environmental Health Sciences, School of Public Health, Peking University, 38 Xueyuan Rd., Haidian District, Beijing, China. Telephone: 86-10-82801522. Email: shaowei_wu@bjmu.edu.cn, or A.A. Baccarelli, Dept. of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 722 West 168th St., ARB 11th Floor 1105E, New York, NY 10032 USA. Telephone: 617-432-0037. Email: ab4303@cumc.columbia.edu Supplemental Material is available online (https://doi.org/10.1289/EHP1246). The authors declare they have no actual or potential competing financial interests. Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehponline@niehs.nih.gov. Our staff will work with you to assess and meet your accessibility needs within 3 working days. Supplemental Material PDF (1.8 MB) Supplemental Code and Data Zip File (17.1 MB) Note to readers with disabilities: EHP h...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research