Finding A Cure Wouldn’t Mean We’ve Defeated Cancer

WebMD wasn't a research option when Ivy Brown was diagnosed with Hodgkin's lymphoma in 1974, so her mother looked up her 12-year-old daughter's condition the old-fashioned way, in a hardcover medical volume. "It just said 'fatal,'" Brown explained. Having moved the family to London a month earlier, Brown's parents were still trying to liaise with her pediatrician in the U.S. "My father told me recently that he was sleeping with the phone on his stomach because of the time change," she said. "They were as scared as you can be when you have a child who you think you might lose," Brown explained. "It was devastating for them." Robin Glassman was also 12 when she was diagnosed with Hodgkin's in 1972. Her mother wouldn't let her read the disease's description.  While the prognosis for Hodgkin's, an immune system cancer, is excellent -- it's considered one of the most curable cancers, with 10-year survival rates of about 80 percent -- that wasn't the case fifty years ago. In the 1960s, only 1 in 10 Hodgkin's patients were expected to survive for five years. Today, the two women are among the first generation of what's referred to as "long-term childhood cancer survivors" -- kids who were diagnosed in the 1970s and lived for at least five years after their initial diagnosis, a benchmark that their peers born just 10 years earlier would not have likely lived to reach. The women's scars are shown here in powerful ph...
Source: Science - The Huffington Post - Category: Science Source Type: news

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Publication date: 1 December 2018Source: Materials Science and Engineering: C, Volume 93Author(s): Anasuya Roy, Mangala Joshi, B.S. Butola, Sahil MalhotraAbstractWith increasing demand for novel and potent antimicrobial agents to combat cross-infections and infectious diseases, silver and copper based nanoparticles (NPs) deposited over supports such as montmorillonite (MMT) are playing a crucial role in shaping the current research scenario. Although materials based on Ag NP and Cu NP on MMT have been reported, its toxicological properties on human cell lines have not been accounted for. This paper reports a comparative st...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
Publication date: Available online 20 August 2018Source: Materials Chemistry and PhysicsAuthor(s): Reza Aghaei, Akbar Eshaghi, Abbas Ali AghaeiAbstractIn this work, hollow SiO2-SiO2 nanocomposite thin film was deposited on a glass substrate by a sol-gel dip-coating method. Transmission electron microscopy (TEM), field emission scanning electron microscopy (FE-SEM) and atomic force microscopy (AFM) were used to investigate the structure and morphology of the nanoparticles and films. Surface wettability and optical properties of the thin films were studied by means of water contact angle analyzer and UV-vis spectrophotometer...
Source: Materials Chemistry and Physics - Category: Materials Science Source Type: research
Publication date: Available online 20 August 2018Source: Biocybernetics and Biomedical EngineeringAuthor(s): R. Sumathi, M. Venkatesuslu, Sridhar P. Arjunan
Source: Biocybernetics and Biomedical Engineering - Category: Biomedical Engineering Source Type: research
Publication date: Available online 20 August 2018Source: NeurocomputingAuthor(s): Junjie Zhang, Yong Xia, Haoyue Zeng, Yanning ZhangAbstractDetection of pulmonary nodules on chest CT is an essential step in the early diagnosis of lung cancer, which is critical for best patient care. In this paper, we propose an automated pulmonary nodule detection algorithm, denoted by NODULe, which jointly uses a conventional method for nodule detection and a deep learning model for genuine nodule identification. Specifically, we first use multi-scale Laplacian of Gaussian (LoG) filters and prior shape and size constraints to detect nodul...
Source: Neurocomputing - Category: Neuroscience Source Type: research
ConclusionLow PNI predicts poor survival in LC patients.
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
Abstract Reduced peak oxygen uptake (VO2peak) is a common clinical finding in progressive Chagas disease. However, the disease stage in which functional impairment is detectable remains uncertain. The present study compared functional capacity between healthy controls and patients with different clinical forms of Chagas disease. A systematic review and meta-analysis (PROSPERO database CRD42017058353) was conducted following a search of the MEDLINE, Web of Science, CINAHL, and LILACS databases from September to December 2017 for articles published in English, Spanish, or Portuguese, with no date restrictions. We included st...
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research
CONCLUSION: We identified a changing pattern of human visceral leishmaniasis occurrence in Ara çatuba: the first period (1999-2009) showed a cyclic pattern, clusters, and presence of spatial dependence in the case point distribution; the second period (2010-2015) showed the lowest rates of all historical series, stable incidence, and cases with a random distribution pattern.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research
A new classification system from ACC/AHA incorporates physiologic factors, not just anatomy alone, which experts say will allow more personalized care of this growing patient population.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Cardiology News Source Type: news
This study investigated the associations between infants’ attention to emotional faces and infants’ and parents’ negative emotions in a community sample. Infants’ (N = 57, Mage = 14.26 months) fixations and pupil responses to fearful, sad, angry versus happy and neutral faces were measured with an eye-tracker. Mothers’ and fathers’ negative emotions (negative affect, depression, and anxiety), and infants’ negative temperament were measured with questionnaires. Infants looked longer at fearful than happy or neutral faces, while they showed less pupil dilation to fearful than to happ...
Source: Infant Behavior and Development - Category: Child Development Source Type: research
Publication date: Available online 20 August 2018Source: Food ControlAuthor(s): Jin-Rong Bai, Kai Zhong, Yan-Ping Wu, Grosu Elena, Hong GaoAbstractThe aim of this study was to evaluate the inhibitory activity of shikimic acid (SA) against biofilm formation of Staphylococcus aureus and to explore its potential molecular mechanism. Crystal violet staining assay showed that SA clearly reduced the biomass of the biofilm at its sub-MICs. Light microscopic images and scanning electron microscope (SEM) observations suggested that SA inhibited the biofilm adhesion on glass slides and induced apparent collapse of biofilm architectu...
Source: Food Control - Category: Food Science Source Type: research
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