Investigational steroid mirrors prednisone's benefits while taming its side effects
(Children's National Health System) A head-to-head trial comparing the decades-old steroid, prednisone, and a promising new steroid, vamorolone, finds both act on the same key set of genetic pathways involved in controlling inflammation, indicates a new study led by Children's National Health System researchers. However, the study suggests the new investigational steroid doesn't activate several additional pathways involved in prednisone's bevy of undesirable side effects. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 20, 2018 Category: International Medicine & Public Health Source Type: news

Medical News Today: How to deal with prednisone withdrawal
Prednisone is a drug that contains synthetic cortisol. When a person takes prednisone, the body stops making enough cortisol on its own. This can lead to withdrawal symptoms when the person stops taking the medication or reduces their dose too quickly. Here, learn more about the symptoms and how to prevent them. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 20, 2018 Category: Consumer Health News Tags: Pharmacy / Pharmacist Source Type: news

Deadly Respiratory Distress Mimic
Medic 534, staffed by a paramedic and EMT, is dispatched to a nursing home for a 78-year-old female in respiratory distress. On arrival, the crew finds the patient in a chair accompanied by two nurses and the administrator on call. The patient is in obvious distress showing fatigue and an increased work of breathing. She is alert to voice, but diaphoretic, lethargic, and unable to speak due to rapid, shallow breathing. A nurse is administering a nebulizer containing 3 mL of albuterol sulfate/ipratropium. A second nurse states that the patient has been in increasing distress for the last 45 minutes. The nurse also says that...
Source: JEMS Patient Care - July 17, 2018 Category: Emergency Medicine Authors: Brenton Faber, PhD, NRP Tags: Airway & Respiratory Patient Care Source Type: news

Adjuvant Docetaxel Fails in Higher-Risk Prostate Cancer
In SPCG-13, adjuvant docetaxel without prednisone did not impact biochemical DFS in intermediate- or high-risk disease treated with radical RT with ADT. (Source: CancerNetwork)
Source: CancerNetwork - June 13, 2018 Category: Cancer & Oncology Authors: Leah Lawrence Source Type: news

Adjuvant Docetaxel Fails in Higher-Risk Prostate Ca
In SPCG-13, adjuvant docetaxel without prednisone did not impact biochemical DFS in intermediate- or high-risk disease treated with radical RT with ADT. (Source: CancerNetwork)
Source: CancerNetwork - June 11, 2018 Category: Cancer & Oncology Authors: Leah Lawrence Source Type: news

No DFS Benefit: Adjuvant Docetaxel in Higher-Risk Prostate Ca
In SPCG-13, adjuvant docetaxel without prednisone did not impact biochemical DFS in intermediate- or high-risk disease treated with radical RT with ADT. (Source: CancerNetwork)
Source: CancerNetwork - June 10, 2018 Category: Cancer & Oncology Authors: Leah Lawrence Source Type: news

ASCO: Overall Survival Up for African - American Men With mCRPC
Improved survival versus Caucasian men treated with docetaxel/prednisone, DP - containing regimen (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - June 7, 2018 Category: Cancer & Oncology Tags: Oncology, Pharmacy, Urology, Conference News, Source Type: news

ASCO: Overall Survival Up for African-American Men With mCRPC
THURSDAY, June 7, 2018 -- Overall survival is increased for African-American men with metastatic castration resistant prostate cancer (mCRPC) versus Caucasian men treated with docetaxel/prednisone (DP) or a DP-containing regimen, according to a... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 7, 2018 Category: Pharmaceuticals Source Type: news

Medical News Today: How does prednisone treat an asthma flare-up?
Prednisone is a steroid that can be used as part of a person's treatment after they have a significant asthma attack. In this article, we examine the effect the drug has on inflammation in the airways to help improve breathing, the possible side effects it can cause, and other medications that may be used alongside it. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 25, 2018 Category: Consumer Health News Tags: Asthma Source Type: news

UAB-led study shows promise for bone density drug
An alternative treatment for people taking glucocorticoids shows promise through a UAB-led study.   Long-term use of these drugs, which includes prednisone, causes osteoporosis, which results in a yearly bone fracture rate of 5 percent.  A UAB-led international study published in “The Lancet Diabetes& Endocrinology ” medical journal, and headed by Kenneth Saag, professor of medicine at UAB, indicates alternative drugs can be effective. The study was funded by Amgen which markets denosumab… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - April 30, 2018 Category: Biotechnology Authors: Tyler Patchen Source Type: news

UAB-led study shows drug effectiveness in reducing glucocorticoid-induced bone loss
(University of Alabama at Birmingham) About one in every 100 people in the world takes glucocorticoids long term to treat immune-mediated diseases. However, glucocorticoids, such as prednisone, have a side effect -- they induce glucocorticoid-induced bone loss, causing an estimated yearly bone fracture rate of 5 percent. An alternative treatment option to the standard treatment now appears promising, according to an international study. Researchers compared the monoclonal antibody denosumab against a standard bisphosphonate. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 27, 2018 Category: International Medicine & Public Health Source Type: news

No Improved Outcomes in Prostate Cancer With ADT Plus Mitoxantrone/Prednisone
Combining mitoxantrone and prednisone with adjuvant androgen deprivation therapy failed to improve overall survival over ADT alone in patients with high-risk prostate cancer. (Source: CancerNetwork)
Source: CancerNetwork - April 18, 2018 Category: Cancer & Oncology Authors: Dave Levitan Tags: Genitourinary Cancers SiteTerms/www.cannabissciencetech.com/News Prostate Cancer Source Type: news

ADT Alone Prevails in High-Risk Prostate Cancer (CME/CE)
(MedPage Today) -- No survival bump with postoperative mitoxantrone, prednisone (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - April 10, 2018 Category: Endocrinology Source Type: news

Abiraterone, Docetaxel Best With ADT for Metastatic Prostate Cancer
Abiraterone plus prednisolone/prednisone, or docetaxel, combined with ADT may be the most effective therapies for metastatic hormone-naive prostate cancer. (Source: CancerNetwork)
Source: CancerNetwork - March 19, 2018 Category: Cancer & Oncology Authors: Dave Levitan Tags: Genitourinary Cancers News Prostate Cancer Source Type: news

Which Combo for Newly Diagnosed Metastatic Prostate Cancer? Which Combo for Newly Diagnosed Metastatic Prostate Cancer?
The combination of abiraterone, prednisone, and castration proves to be a beneficial option for metastatic prostate cancer.Medscape Urology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 9, 2018 Category: Consumer Health News Tags: Urology Commentary Source Type: news

Prednisone vs. Budesonide
Title: Prednisone vs. BudesonideCategory: MedicationsCreated: 2/23/2018 12:00:00 AMLast Editorial Review: 2/23/2018 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - February 23, 2018 Category: Drugs & Pharmacology Source Type: news

Zytiga (abiraterone acetate) Plus Prednisone Approved for Treatment of Earlier Form of Metastatic Prostate Cancer
HORSHAM, PA, Feburary 8, 2018 – The Janssen Pharmaceutical Companies of Johnson& Johnson today announced that the U.S. Food and Drug Administration (FDA) has approved a new indication for Zytiga (abiraterone acetate) in combination with... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - February 8, 2018 Category: Drugs & Pharmacology Source Type: news

ZYTIGA(R) (abiraterone acetate) Plus Prednisone Approved for Treatment of Earlier Form of Metastatic Prostate Cancer
New indication for ZYTIGA® in combination with prednisone provides treatment option for patients with metastatic high-risk castration-sensitive prostate cancer Findings from pivotal Phase 3 LATITUDE clinical trial data demonstrated statistically sig... Biopharmaceuticals, Oncology, FDA Janssen Pharmaceutical, ZYTIGA, abiraterone, prostate cancer (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - February 8, 2018 Category: Pharmaceuticals Source Type: news

ZYTIGA ® (abiraterone acetate) Plus Prednisone Approved for Treatment of Earlier Form of Metastatic Prostate Cancer
(Source: Johnson and Johnson)
Source: Johnson and Johnson - February 8, 2018 Category: Pharmaceuticals Source Type: news

QOL Data Reassuring for Abiraterone in Prostate Cancer QOL Data Reassuring for Abiraterone in Prostate Cancer
A new analysis of the LATITUDE trial shows that addition of abiraterone plus prednisone to ADT improves not only survival but also pain, fatigue, and quality of life (QOL).Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 24, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

DARZALEX(R) (daratumumab) Combination Regimen Significantly Improved Outcomes for Newly Diagnosed Multiple Myeloma Patients who are Transplant Ineligible
Phase 3 ALCYONE data showed DARZALEX in combination with bortezomib, melphalan and prednisone meaningfully improved progression-free survival and response rates Data featured as late-breaker at ASH 2017 (Abstract #LBA-4) and published in the New England... Biopharmaceuticals, Oncology Janssen Biotech, DARZALEX, daratumumab, multiple myeloma (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - December 12, 2017 Category: Pharmaceuticals Source Type: news

30.11.17: Not intended for U.S. and UK Media
Phase III trial of radium-223 dichloride in combination with abiraterone acetate and prednisone/prednisolone for patients with metastatic castration-resistant prostate cancer unblinded earlyDecision follows a recommendation from an Independent Data Monitoring Committeemehr ... (Source: Bayer IR Newsfeed: Events)
Source: Bayer IR Newsfeed: Events - November 29, 2017 Category: Pharmaceuticals Source Type: news

Prednisone vs. Prednisolone
Title: Prednisone vs. PrednisoloneCategory: MedicationsCreated: 11/1/2017 12:00:00 AMLast Editorial Review: 11/1/2017 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - November 1, 2017 Category: Drugs & Pharmacology Source Type: news

Prednisone vs. Dexamethasone
Title: Prednisone vs. DexamethasoneCategory: MedicationsCreated: 10/31/2017 12:00:00 AMLast Editorial Review: 10/31/2017 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - October 31, 2017 Category: Drugs & Pharmacology Source Type: news

Prednisone vs. Hydrocortisone
Title: Prednisone vs. HydrocortisoneCategory: MedicationsCreated: 10/31/2017 12:00:00 AMLast Editorial Review: 10/31/2017 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - October 31, 2017 Category: Drugs & Pharmacology Source Type: news

Abiraterone Improves Outcomes in Metastatic Prostate Cancer Abiraterone Improves Outcomes in Metastatic Prostate Cancer
Abiraterone acetate plus prednisone improves outcomes in men with chemotherapy-naive, metastatic, castration-resistant prostate cancer (mCRPC), regardless of baseline risk factors, according to results from the phase 3 COU-AA-302 study.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - October 10, 2017 Category: Surgery Tags: Hematology-Oncology News Source Type: news

Janssen Submits Supplemental New Drug Application to U.S. FDA for ZYTIGA ® (abiraterone acetate) to Treat Men with Earlier Stages of Metastatic Prostate Cancer
Filing Supported by Data from Pivotal LATITUDE Trial Evaluating ZYTIGA ® in Combination with Prednisone and Androgen Deprivation Therapy (ADT) (Source: Johnson and Johnson)
Source: Johnson and Johnson - September 14, 2017 Category: Pharmaceuticals Source Type: news

Pregnant With a Rare Vasculitis: How to Treat Pregnant With a Rare Vasculitis: How to Treat
Dr Stephen Paget reviews the case of a 40-year-old woman with Takayasu arteritis being treated with prednisone.Hospital for Special Surgery (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 13, 2017 Category: Consumer Health News Tags: Rheumatology Commentary Source Type: news

New Data Presented at ESMO 2017 Shows That Abiraterone Acetate Plus Prednisone Provides Benefits in Patient Reported Outcomes in Both Metastatic Hormone-Sensitive and Castration-Resistant Prostate Cancer
(Source: Johnson and Johnson)
Source: Johnson and Johnson - September 8, 2017 Category: Pharmaceuticals Source Type: news

What Are the Side Effects of Prednisone for Ankylosing Spondylitis?
Title: What Are the Side Effects of Prednisone for Ankylosing Spondylitis?Category: Doctor's& Expert's views on SymptomsCreated: 8/29/2017 12:00:00 AMLast Editorial Review: 8/29/2017 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - August 29, 2017 Category: Rheumatology Source Type: news

New Data Change Metastatic Prostate Cancer Treatment Paradigm New Data Change Metastatic Prostate Cancer Treatment Paradigm
Dr Chodak reviews results of the LATITUDE trial, which compared ADT alone versus ADT with abiraterone acetate plus prednisone.Medscape Urology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 14, 2017 Category: Consumer Health News Tags: Urology Commentary Source Type: news

Tocilizumab With Steroid Taper Superior in GCA Tocilizumab With Steroid Taper Superior in GCA
Tocilizumab plus a 26-week prednisone taper was superior to either a short or long course of tapered prednisone treatment plus placebo in patients with giant cell arteritis, a study has found.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 27, 2017 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Top 5 Tips On Traveling With A Life-Threatening Food Allergy
Traveling with a food allergy or other dietary restrictions can be a scary experience. It’s even more scary when you have had a near-death allergic reaction. Several years ago, I had an allergic reaction after eating some contaminated food in Spain. Thankfully, I survived that trip, but I’ve been much more prepared and cautious during my travels. Here are my top 5 tips: 1. Bring multiple EpiPens. EpiPens are the single most important thing to take with you because they buy you time to get emergency care. A few minutes can mean life or death. In my Spain case, the nurse said that if my travel partner, Daraius, h...
Source: Healthy Living - The Huffington Post - June 14, 2017 Category: Consumer Health News Source Type: news

New study highlights patient concerns about glucocorticoid side effects
This study has shown that weight gain, insomnia and moon face were the top three most important side effects to patients taking glucocorticoids. Despite this, they are not widely studied, with many unanswered questions. "Research should be informed by patients, and targeted to provide patients with better information about these side effects of high importance." Arthritis Research UK's view Devi Rani Sagar, research liaison manager at Arthritis Research UK, said:"We believe that people with arthritis should get the recognition and support they deserve, and that's why we invest in research to find the...
Source: Arthritis Research UK - June 13, 2017 Category: Rheumatology Source Type: news

Prednisone may improve effectiveness of AAV-based gene therapy by reducing immune response
(Mary Ann Liebert, Inc./Genetic Engineering News) A new study of gene transfer using adeno-associated virus (AAV)-based gene delivery into skeletal muscle of rhesus macaques showed that oral prednisone reduced immune responses to AAV that can weaken expression of the therapeutic transgene over time. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - June 9, 2017 Category: Biology Source Type: news

Abiraterone/ADT Combo Increased Prostate Cancer Survival
Combined therapy with abiraterone acetate/prednisone plus ADT significantly improved overall survival and radiographic progression-free survival among men with metastatic hormone-naive prostate cancer. (Source: CancerNetwork)
Source: CancerNetwork - June 3, 2017 Category: Cancer & Oncology Authors: Leah Lawrence Tags: Conferences/ASCO Prostate Cancer News Source Type: news

Weekly steroids strengthen and repair muscles
(Northwestern University) In a surprising finding, weekly doses of glucocorticoid steroids, such as prednisone, help speed recovery in muscle injuries, reports a new study. The weekly steroids also repaired muscles damaged by muscular dystrophy. When given daily over long periods, prednisone can cause muscle wasting. But the once weekly doses of the steroid increased proteins that stimulate muscle repair. The studies were conducted in mice, with broad implications for humans. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 16, 2017 Category: International Medicine & Public Health Source Type: news

CAMERA Data Support MTX + Pred as Initial Early RA Treatment CAMERA Data Support MTX + Pred as Initial Early RA Treatment
Patients with early RA randomly assigned to MTX with vs without prednisone in the CAMERA trial showed better outcomes and less need for bDMARDs in the former MTX + pred group.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 11, 2017 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Got hives? Hold the steroids
(American College of Emergency Physicians) Despite standard use for the itching associated with urticaria (commonly known as hives), prednisone (a steroid) offered no additional relief to emergency patients suffering from hives than a placebo did, according to a randomized, placebo-controlled, double-blind, parallel-group study published online yesterday in Annals of Emergency Medicine ('Levocetirizine and Prednisone Are Not Superior to Levocetirizine Alone for the Treatment of Acute Urticaria: A Randomized Double-Blind Clinical Trial'). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 3, 2017 Category: Global & Universal Source Type: news

Medical News Today: Prednisone and diabetes: What is the connection?
Prednisone is a steroid used to treat autoimmune disorders, but it can also affect how the body reacts to insulin. Learn more in this article. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 20, 2017 Category: Consumer Health News Tags: Diabetes Source Type: news

Custirsen Does Not Improve Overall Survival in mCRPC
The addition of custirsen to docetaxel and prednisone failed to improve overall survival among patients with metastatic castration-resistant prostate cancer in a phase III trial. (Source: CancerNetwork)
Source: CancerNetwork - March 31, 2017 Category: Cancer & Oncology Authors: Dave Levitan Tags: Genitourinary Cancers News Prostate Cancer Source Type: news

Osteoporosis and long-term prednisone: What is the risk?
(Source: MayoClinic.com - Ask a Specialist)
Source: MayoClinic.com - Ask a Specialist - March 3, 2017 Category: Consumer Health News Source Type: news

Prednisone Attenuates IRIS in TB-HIV (CME/CE)
(MedPage Today) -- Trial suggests use of the steroid with TB treatment reduces risk of complications (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - February 17, 2017 Category: Infectious Diseases Source Type: news

Rayos (Prednisone Delayed-Release Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - January 24, 2017 Category: Drugs & Pharmacology Source Type: news

Deltasone (Prednisone) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - January 24, 2017 Category: Drugs & Pharmacology Source Type: news

Data Lacking on Prednisone Use in RA (CME/CE)
(MedPage Today) -- Glucocorticoid treatment may be the best and worst possible option (Source: MedPage Today Geriatrics)
Source: MedPage Today Geriatrics - January 5, 2017 Category: Geriatrics Source Type: news

Researchers Suggest Caution in Treating Lupus Patients With Early, Higher-Dose Prednisone
No abstract available (Source: Lippincott's Bone and Joint Newsletter)
Source: Lippincott's Bone and Joint Newsletter - November 19, 2016 Category: Orthopaedics Tags: Trends and Innovations Source Type: news

Amgen Announces Top-Line Results From Phase 3 KYPROLIS ® (Carfilzomib) CLARION Study In Newly Diagnosed Multiple Myeloma Patients
Amgen to Hold Analyst Call Today at 8:30 a.m. ET THOUSAND OAKS, Calif., Sept. 27, 2016 /PRNewswire/ -- Amgen (NASDAQ:AMGN) today announced top-line results of the Phase 3 CLARION trial, which evaluated an investigational regimen of KYPROLIS® (carfilzomib), melphalan and prednisone (KMP) versus Velcade® (bortezomib), melphalan and prednisone (VMP) for 54 weeks in patients with newly diagnosed multiple myeloma who were ineligible for hematopoietic stem-cell transplant. The trial did not meet the primary endpoint of superiority in progression-free survival (PFS) (median PFS 22.3 months for KMP versus 22...
Source: Amgen News Release - September 27, 2016 Category: Pharmaceuticals Tags: Uncategorized Source Type: news

Deflazacort Improves Muscle Strength in Duchenne MD Deflazacort Improves Muscle Strength in Duchenne MD
The drug showed efficacy similar to that of prednisone, but significantly less weight gain, in a trial conducted more than 20 years ago. The FDA has accepted the company's NDA and granted a priority review.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - September 8, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Humira Provides Effective, Non-Steroid Alternative for Eye Inflammation
Contact: Amara Omeokwe Phone: 919-681-4239 Email:amara.omeokwe@duke.eduhttps://www.dukehealth.orgHumira Provides Effective, Non-Steroid Alternative for Eye InflammationEMBARGOED FOR RELEASE until 5 p.m. (ET) on Wednesday, September 7, 2016DURHAM, N.C. -- Patients suffering from noninfectious uveitis, a group of diseases that causes eye inflammation, can get effective treatment from a corticosteroid alternative that has previously been approved for treatment of arthritis and Crohn ’s disease, according to a study led by a Duke Health researcher.The Food& Drug Administration recently approved the additional use of ...
Source: DukeHealth.org: Duke Health Features - September 8, 2016 Category: Pediatrics Tags: Duke Medicine Source Type: news