Methionine-choline deficient diet deteriorates DSS-induced murine colitis through disturbance of gut microbes and infiltration of macrophages
In conclusion, this study supports the concept that intake of MCD predisposes to experimental colitis and enhances its pathogenesis via modulating gut microbes and macrophages in mice.PMID:38684800 | DOI:10.1038/s41401-024-01291-y (Source: Acta Pharmacologica Sinica)
Source: Acta Pharmacologica Sinica - April 29, 2024 Category: Drugs & Pharmacology Authors: Mo-Ting Liu Yao Zhang Cai-Gui Xiang Tao Yang Xiao-Han Wang Qiu-Kai Lu Hui-Min Lu Chen Fan Chun-Lan Feng Xiao-Qian Yang Duo-Wu Zou Heng Li Wei Tang Source Type: research
Optimal human ovarian follicle isolation: A review focused on enzymatic digestion
Histol Histopathol. 2024 Apr 12:18747. doi: 10.14670/HH-18-747. Online ahead of print.ABSTRACTThe damage or depletion of ovarian reserves due to aging or cancer treatment can increase the need for fertility preservation techniques. One of the most common ways of supporting fertility in prepubertal girls and women who require immediate cancer treatment is through ovarian tissue cryopreservation and re-transplantation following cancer treatment. However, a more appropriate method should be employed in diseases such as leukemia, where malignant cells may be present in cryopreserved tissue, instead of ovarian tissue transplant...
Source: Histology and Histopathology - April 29, 2024 Category: Cytology Authors: Farnaz Tajbakhsh Somayeh Tavana Mohammad Kazemi Ashtiani Christiani Andrade Amorim Rouhollah Fathi Source Type: research
Hematopoietic Stem Cell Transplantation in Sickle Cell Disease: A Multidimentional Review
Cell Transplant. 2024 Jan-Dec;33:9636897241246351. doi: 10.1177/09636897241246351.ABSTRACTWhile exagamglogene autotemcel (Casgevy) and lovotibeglogene autotemcel (Lyfgenia) have been approved by the US Food and Drug Administration (FDA) as the first cell-based gene therapies for the treatment of patients 12 years of age and older with sickle cell disease (SCD), this treatment is not universally accessible. Allogeneic hematopoietic stem cell transplant (HSCT) has the potential to eradicate the symptoms of patients with SCD, but a significant obstacle in HSCT for SCD is the availability of suitable donors, particularly human...
Source: Cell Transplantation - April 29, 2024 Category: Cytology Authors: Tahereh Rostami Soroush Rad Mohammad Reza Rostami Seied Amirhossein Mirhosseini Hediyeh Alemi Naghmeh Khavandgar Ghasem Janbabai Azadeh Kiumarsi Amir Kasaeian Seied Asadollah Mousavi Source Type: research
QiDongNing induces lung cancer cell apoptosis via triggering P53/DRP1-mediated mitochondrial fission
In conclusion, QDN induced apoptosis via triggering p53/DRP1-mediated mitochondrial fission in NSCLC cells.PMID:38682742 | DOI:10.1111/jcmm.18353 (Source: J Cell Mol Med)
Source: J Cell Mol Med - April 29, 2024 Category: Molecular Biology Authors: Rongzhen Ding Yichao Wang Ling Xu Shuliu Sang Guanjin Wu Wenxiao Yang Yilu Zhang Chengyan Wang Ao Qi Haiping Xie Yi Liu Aiguo Dai Lijing Jiao Source Type: research
QiDongNing induces lung cancer cell apoptosis via triggering P53/DRP1-mediated mitochondrial fission
In conclusion, QDN induced apoptosis via triggering p53/DRP1-mediated mitochondrial fission in NSCLC cells.PMID:38682742 | PMC:PMC11057058 | DOI:10.1111/jcmm.18353 (Source: Molecular Medicine)
Source: Molecular Medicine - April 29, 2024 Category: Molecular Biology Authors: Rongzhen Ding Yichao Wang Ling Xu Shuliu Sang Guanjin Wu Wenxiao Yang Yilu Zhang Chengyan Wang Ao Qi Haiping Xie Yi Liu Aiguo Dai Lijing Jiao Source Type: research
Mortality rate after total knee arthroplasty or total hip arthroplasty in patients with a history of liver transplant
World J Orthop. 2024 Apr 18;15(4):310-311. doi: 10.5312/wjo.v15.i4.310. eCollection 2024 Apr 18.ABSTRACTIn this editorial I comment on the article by Ahmed et al published in a recent issue of the World J Orthop 2023; 14: 784-790. It is well known that patients who have undergone a liver transplant (LT) may need to have a total hip arthroplasty (THA) or total knee arthroplasty (TKA) implanted. Ahmed et al stated that the mortality rate in these patients was similar to the one of the general population. However, there are three articles previously published that found higher mortality in LT patients who experienced THA/TKA ...
Source: World Journal of Orthopaedics - April 29, 2024 Category: Orthopaedics Authors: E Carlos Rodriguez-Merchan Source Type: research
Editorial introduction
Curr Opin Organ Transplant. 2024 Jun 1;29(3):v. doi: 10.1097/MOT.0000000000001148. Epub 2024 May 1.NO ABSTRACTPMID:38682654 | DOI:10.1097/MOT.0000000000001148 (Source: Current Opinion in Organ Transplantation)
Source: Current Opinion in Organ Transplantation - April 29, 2024 Category: Transplant Surgery Source Type: research
Machine wars and policy provisions: how the landscape of organ procurement and allocation is changing in the United States
Curr Opin Organ Transplant. 2024 Jun 1;29(3):173-174. doi: 10.1097/MOT.0000000000001145. Epub 2024 May 1.NO ABSTRACTPMID:38682655 | DOI:10.1097/MOT.0000000000001145 (Source: Current Opinion in Organ Transplantation)
Source: Current Opinion in Organ Transplantation - April 29, 2024 Category: Transplant Surgery Authors: Anji Wall Source Type: research
Zinc and Chronic Kidney Disease: A Review
J Nutr Sci Vitaminol (Tokyo). 2024;70(2):98-105. doi: 10.3177/jnsv.70.98.ABSTRACTChronic kidney disease (CKD) poses a major global public health challenge. The World Health Organization's data shows that CKD affects about 10% of the world's population, particularly in low- and middle-income countries. Due to limited access to diagnosis and treatment, CKD has become the 12th leading cause of death worldwide. The advanced stage of CKD can lead to kidney failure, which is clinically referred to as end-stage renal disease (ESRD). In such cases, patients can only sustain life through dialysis or kidney transplantation. However,...
Source: Journal of Nutritional Science and Vitaminology - April 29, 2024 Category: Nutrition Authors: Wanqiu Chen Hongtao Lu Yajing Ying Hongxia Li Hui Shen Jianming Cai Source Type: research
Angiotensin-converting-enzyme inhibitors and angiotensin receptor blockers for preventing the progression of diabetic kidney disease
CONCLUSIONS: ACEi or ARB may make little or no difference to all-cause and cardiovascular death compared to placebo or no treatment in people with diabetes and kidney disease but may prevent kidney failure. ARB may prevent the doubling of SCr and the progression from microalbuminuria to macroalbuminuria compared with a placebo or no treatment. Despite the international guidelines suggesting not combining ACEi and ARB treatment, the effects of ACEi or ARB monotherapy compared to dual therapy have not been adequately assessed. The limited data availability and the low quality of the included studies prevented the assessment ...
Source: Cochrane Database of Systematic Reviews - April 29, 2024 Category: General Medicine Authors: Patrizia Natale Suetonia C Palmer Sankar D Navaneethan Jonathan C Craig Giovanni Fm Strippoli Source Type: research
Hepatocellular carcinoma and musculoskeletal system: A narrative literature review
World J Gastroenterol. 2024 Apr 21;30(15):2109-2117. doi: 10.3748/wjg.v30.i15.2109.ABSTRACTMusculoskeletal alterations in hepatocellular carcinoma (HCC) are less common than liver-related complications. However, they can significantly impact the quality of life and overall prognosis of patients with HCC. The main obstacle in the clinical assessment of HCC-induced musculoskeletal alterations is related to effective and timely diagnosis because these complications are often asymptomatic and unapparent during routine clinical evaluations. This narrative literature review aimed to provide a comprehensive overview of the contem...
Source: World Journal of Gastroenterology - April 29, 2024 Category: Gastroenterology Authors: Jelena Jadzic Danijela Djonic Source Type: research
The association between vascular access satisfaction and all-cause mortality in maintenance hemodialysis patients
J Vasc Access. 2024 Apr 29:11297298241244483. doi: 10.1177/11297298241244483. Online ahead of print.ABSTRACTBACKGROUND: The mortality is significantly higher in patients undergoing maintenance hemodialysis (MHD) than in the general population. It is well-known that vascular access (VA) is critical for MHD patients. But the association between VA satisfaction and all-cause mortality in MHD patients is still not clear. The aim of this study was to explore the relationship between VA satisfaction and all-cause mortality in MHD patients with a 30-month follow-up.METHODS: Two hundred twenty-nine MHD patients in two dialysis cen...
Source: The Journal of Vascular Access - April 29, 2024 Category: Surgery Authors: Liu-Ping Zhang Meng-Ting Li Meng-Jiao Pan Yu-Tong Ou Min Gao Min Wu Source Type: research
Primary peritoneal carcinoma presented with abdominal pain in patient with kidney transplantation
Korean J Intern Med. 2024 Apr 29. doi: 10.3904/kjim.2023.254. Online ahead of print.NO ABSTRACTPMID:38680009 | DOI:10.3904/kjim.2023.254 (Source: The Korean Journal of Internal Medicine)
Source: The Korean Journal of Internal Medicine - April 29, 2024 Category: Internal Medicine Authors: Eunmi Jo Sang Heon Song Source Type: research
Results of Autologous Hematopoietic Stem Cell Transplantation in Patients with Multiple Myeloma(MM) and Renal Impairment: A Retrospective Single-Center Study
Conclusion: Auto-HSCT is a safe and effective treatment for patients with MM complicated by acute kidney injury. Fourteen of 23 (61%) patients became dialysis-independent.PMID:38680711 | PMC:PMC11055427 | DOI:10.18502/ijhoscr.v18i1.14745 (Source: Herpes)
Source: Herpes - April 29, 2024 Category: Infectious Diseases Authors: Maiia Soloveva Maxim Solovev Daria Mironova Larisa Mendeleeva Source Type: research
Current status of liver transplantation for human immunodeficiency virus-infected patients in mainland China
This study provides an overview of the current landscape of HIV-positive patients receiving liver transplantation (LT) in mainland China. To date, our transplant center has conducted LT for eight end-stage liver disease patients co-infected with HIV, and all but one, who died two months postoperatively due to sepsis and progressive multi-organ failure, have survived. Comparative analysis with hepatitis B virus-infected patients during the same period revealed no statistically significant differences in acute rejection reactions, cytomegalovirus infection, bacteremia, pulmonary infections, acute kidney injury, new-onset can...
Source: World Journal of Gastroenterology - April 29, 2024 Category: Gastroenterology Authors: Jian-Xin Tang Dong Zhao Source Type: research
