Evaluation of the Clinical Efficacy of Stem Cell Transplantation in the Treatment of Spinal Cord Injury: A Systematic Review and Meta-analysis
Cell Transplant. 2021 Jan-Dec;30:9636897211067804. doi: 10.1177/09636897211067804.ABSTRACTStem cell transplantation has been applied to treat spinal cord injury (SCI) in clinical trials for many years. However, the clinical efficacies of stem cell transplantation in SCI have been quite diverse. The purpose of our study was to systematically investigate the efficacy of stem cell transplantation in patients with SCI. The PubMed, Web of Science, Ovid-Medline, Cochrane Library, China National Knowledge Infrastructure, VIP, Wanfang, and SinoMed databases were searched until October 27, 2020. Quantitative and qualitative data we...
Source: Cell Transplantation - December 23, 2021 Category: Cytology Authors: Qiao-Rui Tang Hui Xue Qiao Zhang Ying Guo Hao Xu Ying Liu Jia-Mei Liu Source Type: research

Complete Restoration of Motor Function in Acute Cerebral Stroke Treated with Allogeneic Human Umbilical Cord Blood Monocytes: Preliminary Results of a phase I Clinical Trial
Cell Transplant. 2021 Jan-Dec;30:9636897211067447. doi: 10.1177/09636897211067447.ABSTRACTStem cell therapy has been explored for the treatment of cerebral stroke. Several types of stem cells have been investigated to ensure the safety and efficacy in clinical trials.Cryopreserved umbilical cord blood (UCB) mononuclear cells (MNCs) obtained from healthy donors have a more stabilized quality, thereby ensuring a successful therapy. A phase I study was conducted on patients aged 45-80 years who sustained acute ischemic stroke. An UCB unit was obtained from a public cord blood bank based on ABO/Rh blood type, HLA matching scor...
Source: Cell Transplantation - December 23, 2021 Category: Cytology Authors: Tian-Kuo Lee Cheng-You Lu Sheng-Tzung Tsai Pao-Hui Tseng Yu-Chen Lin Shinn-Zong Lin Jonas C Wang Chih-Yang Huang Tsung-Lang Chiu Source Type: research

Evaluation of the Clinical Efficacy of Stem Cell Transplantation in the Treatment of Spinal Cord Injury: A Systematic Review and Meta-analysis
Cell Transplant. 2021 Jan-Dec;30:9636897211067804. doi: 10.1177/09636897211067804.ABSTRACTStem cell transplantation has been applied to treat spinal cord injury (SCI) in clinical trials for many years. However, the clinical efficacies of stem cell transplantation in SCI have been quite diverse. The purpose of our study was to systematically investigate the efficacy of stem cell transplantation in patients with SCI. The PubMed, Web of Science, Ovid-Medline, Cochrane Library, China National Knowledge Infrastructure, VIP, Wanfang, and SinoMed databases were searched until October 27, 2020. Quantitative and qualitative data we...
Source: Cell Transplantation - December 23, 2021 Category: Cytology Authors: Qiao-Rui Tang Hui Xue Qiao Zhang Ying Guo Hao Xu Ying Liu Jia-Mei Liu Source Type: research

Complete Restoration of Motor Function in Acute Cerebral Stroke Treated with Allogeneic Human Umbilical Cord Blood Monocytes: Preliminary Results of a phase I Clinical Trial
Cell Transplant. 2021 Jan-Dec;30:9636897211067447. doi: 10.1177/09636897211067447.ABSTRACTStem cell therapy has been explored for the treatment of cerebral stroke. Several types of stem cells have been investigated to ensure the safety and efficacy in clinical trials.Cryopreserved umbilical cord blood (UCB) mononuclear cells (MNCs) obtained from healthy donors have a more stabilized quality, thereby ensuring a successful therapy. A phase I study was conducted on patients aged 45-80 years who sustained acute ischemic stroke. An UCB unit was obtained from a public cord blood bank based on ABO/Rh blood type, HLA matching scor...
Source: Cell Transplantation - December 23, 2021 Category: Cytology Authors: Tian-Kuo Lee Cheng-You Lu Sheng-Tzung Tsai Pao-Hui Tseng Yu-Chen Lin Shinn-Zong Lin Jonas C Wang Chih-Yang Huang Tsung-Lang Chiu Source Type: research

Evaluation of the Clinical Efficacy of Stem Cell Transplantation in the Treatment of Spinal Cord Injury: A Systematic Review and Meta-analysis
Cell Transplant. 2021 Jan-Dec;30:9636897211067804. doi: 10.1177/09636897211067804.ABSTRACTStem cell transplantation has been applied to treat spinal cord injury (SCI) in clinical trials for many years. However, the clinical efficacies of stem cell transplantation in SCI have been quite diverse. The purpose of our study was to systematically investigate the efficacy of stem cell transplantation in patients with SCI. The PubMed, Web of Science, Ovid-Medline, Cochrane Library, China National Knowledge Infrastructure, VIP, Wanfang, and SinoMed databases were searched until October 27, 2020. Quantitative and qualitative data we...
Source: Cell Transplantation - December 23, 2021 Category: Cytology Authors: Qiao-Rui Tang Hui Xue Qiao Zhang Ying Guo Hao Xu Ying Liu Jia-Mei Liu Source Type: research

Complete Restoration of Motor Function in Acute Cerebral Stroke Treated with Allogeneic Human Umbilical Cord Blood Monocytes: Preliminary Results of a phase I Clinical Trial
Cell Transplant. 2021 Jan-Dec;30:9636897211067447. doi: 10.1177/09636897211067447.ABSTRACTStem cell therapy has been explored for the treatment of cerebral stroke. Several types of stem cells have been investigated to ensure the safety and efficacy in clinical trials.Cryopreserved umbilical cord blood (UCB) mononuclear cells (MNCs) obtained from healthy donors have a more stabilized quality, thereby ensuring a successful therapy. A phase I study was conducted on patients aged 45-80 years who sustained acute ischemic stroke. An UCB unit was obtained from a public cord blood bank based on ABO/Rh blood type, HLA matching scor...
Source: Cell Transplantation - December 23, 2021 Category: Cytology Authors: Tian-Kuo Lee Cheng-You Lu Sheng-Tzung Tsai Pao-Hui Tseng Yu-Chen Lin Shinn-Zong Lin Jonas C Wang Chih-Yang Huang Tsung-Lang Chiu Source Type: research

Evaluation of the Clinical Efficacy of Stem Cell Transplantation in the Treatment of Spinal Cord Injury: A Systematic Review and Meta-analysis
Cell Transplant. 2021 Jan-Dec;30:9636897211067804. doi: 10.1177/09636897211067804.ABSTRACTStem cell transplantation has been applied to treat spinal cord injury (SCI) in clinical trials for many years. However, the clinical efficacies of stem cell transplantation in SCI have been quite diverse. The purpose of our study was to systematically investigate the efficacy of stem cell transplantation in patients with SCI. The PubMed, Web of Science, Ovid-Medline, Cochrane Library, China National Knowledge Infrastructure, VIP, Wanfang, and SinoMed databases were searched until October 27, 2020. Quantitative and qualitative data we...
Source: Cell Transplantation - December 23, 2021 Category: Cytology Authors: Qiao-Rui Tang Hui Xue Qiao Zhang Ying Guo Hao Xu Ying Liu Jia-Mei Liu Source Type: research

Complete Restoration of Motor Function in Acute Cerebral Stroke Treated with Allogeneic Human Umbilical Cord Blood Monocytes: Preliminary Results of a phase I Clinical Trial
Cell Transplant. 2021 Jan-Dec;30:9636897211067447. doi: 10.1177/09636897211067447.ABSTRACTStem cell therapy has been explored for the treatment of cerebral stroke. Several types of stem cells have been investigated to ensure the safety and efficacy in clinical trials.Cryopreserved umbilical cord blood (UCB) mononuclear cells (MNCs) obtained from healthy donors have a more stabilized quality, thereby ensuring a successful therapy. A phase I study was conducted on patients aged 45-80 years who sustained acute ischemic stroke. An UCB unit was obtained from a public cord blood bank based on ABO/Rh blood type, HLA matching scor...
Source: Cell Transplantation - December 23, 2021 Category: Cytology Authors: Tian-Kuo Lee Cheng-You Lu Sheng-Tzung Tsai Pao-Hui Tseng Yu-Chen Lin Shinn-Zong Lin Jonas C Wang Chih-Yang Huang Tsung-Lang Chiu Source Type: research

Evaluation of the Clinical Efficacy of Stem Cell Transplantation in the Treatment of Spinal Cord Injury: A Systematic Review and Meta-analysis
Cell Transplant. 2021 Jan-Dec;30:9636897211067804. doi: 10.1177/09636897211067804.ABSTRACTStem cell transplantation has been applied to treat spinal cord injury (SCI) in clinical trials for many years. However, the clinical efficacies of stem cell transplantation in SCI have been quite diverse. The purpose of our study was to systematically investigate the efficacy of stem cell transplantation in patients with SCI. The PubMed, Web of Science, Ovid-Medline, Cochrane Library, China National Knowledge Infrastructure, VIP, Wanfang, and SinoMed databases were searched until October 27, 2020. Quantitative and qualitative data we...
Source: Cell Transplantation - December 23, 2021 Category: Cytology Authors: Qiao-Rui Tang Hui Xue Qiao Zhang Ying Guo Hao Xu Ying Liu Jia-Mei Liu Source Type: research

Complete Restoration of Motor Function in Acute Cerebral Stroke Treated with Allogeneic Human Umbilical Cord Blood Monocytes: Preliminary Results of a phase I Clinical Trial
Cell Transplant. 2021 Jan-Dec;30:9636897211067447. doi: 10.1177/09636897211067447.ABSTRACTStem cell therapy has been explored for the treatment of cerebral stroke. Several types of stem cells have been investigated to ensure the safety and efficacy in clinical trials.Cryopreserved umbilical cord blood (UCB) mononuclear cells (MNCs) obtained from healthy donors have a more stabilized quality, thereby ensuring a successful therapy. A phase I study was conducted on patients aged 45-80 years who sustained acute ischemic stroke. An UCB unit was obtained from a public cord blood bank based on ABO/Rh blood type, HLA matching scor...
Source: Cell Transplantation - December 23, 2021 Category: Cytology Authors: Tian-Kuo Lee Cheng-You Lu Sheng-Tzung Tsai Pao-Hui Tseng Yu-Chen Lin Shinn-Zong Lin Jonas C Wang Chih-Yang Huang Tsung-Lang Chiu Source Type: research

Evaluation of the Clinical Efficacy of Stem Cell Transplantation in the Treatment of Spinal Cord Injury: A Systematic Review and Meta-analysis
Cell Transplant. 2021 Jan-Dec;30:9636897211067804. doi: 10.1177/09636897211067804.ABSTRACTStem cell transplantation has been applied to treat spinal cord injury (SCI) in clinical trials for many years. However, the clinical efficacies of stem cell transplantation in SCI have been quite diverse. The purpose of our study was to systematically investigate the efficacy of stem cell transplantation in patients with SCI. The PubMed, Web of Science, Ovid-Medline, Cochrane Library, China National Knowledge Infrastructure, VIP, Wanfang, and SinoMed databases were searched until October 27, 2020. Quantitative and qualitative data we...
Source: Cell Transplantation - December 23, 2021 Category: Cytology Authors: Qiao-Rui Tang Hui Xue Qiao Zhang Ying Guo Hao Xu Ying Liu Jia-Mei Liu Source Type: research

Complete Restoration of Motor Function in Acute Cerebral Stroke Treated with Allogeneic Human Umbilical Cord Blood Monocytes: Preliminary Results of a phase I Clinical Trial
Cell Transplant. 2021 Jan-Dec;30:9636897211067447. doi: 10.1177/09636897211067447.ABSTRACTStem cell therapy has been explored for the treatment of cerebral stroke. Several types of stem cells have been investigated to ensure the safety and efficacy in clinical trials.Cryopreserved umbilical cord blood (UCB) mononuclear cells (MNCs) obtained from healthy donors have a more stabilized quality, thereby ensuring a successful therapy. A phase I study was conducted on patients aged 45-80 years who sustained acute ischemic stroke. An UCB unit was obtained from a public cord blood bank based on ABO/Rh blood type, HLA matching scor...
Source: Cell Transplantation - December 23, 2021 Category: Cytology Authors: Tian-Kuo Lee Cheng-You Lu Sheng-Tzung Tsai Pao-Hui Tseng Yu-Chen Lin Shinn-Zong Lin Jonas C Wang Chih-Yang Huang Tsung-Lang Chiu Source Type: research

Evaluation of the Clinical Efficacy of Stem Cell Transplantation in the Treatment of Spinal Cord Injury: A Systematic Review and Meta-analysis
Cell Transplant. 2021 Jan-Dec;30:9636897211067804. doi: 10.1177/09636897211067804.ABSTRACTStem cell transplantation has been applied to treat spinal cord injury (SCI) in clinical trials for many years. However, the clinical efficacies of stem cell transplantation in SCI have been quite diverse. The purpose of our study was to systematically investigate the efficacy of stem cell transplantation in patients with SCI. The PubMed, Web of Science, Ovid-Medline, Cochrane Library, China National Knowledge Infrastructure, VIP, Wanfang, and SinoMed databases were searched until October 27, 2020. Quantitative and qualitative data we...
Source: Cell Transplantation - December 23, 2021 Category: Cytology Authors: Qiao-Rui Tang Hui Xue Qiao Zhang Ying Guo Hao Xu Ying Liu Jia-Mei Liu Source Type: research

Complete Restoration of Motor Function in Acute Cerebral Stroke Treated with Allogeneic Human Umbilical Cord Blood Monocytes: Preliminary Results of a phase I Clinical Trial
Cell Transplant. 2021 Jan-Dec;30:9636897211067447. doi: 10.1177/09636897211067447.ABSTRACTStem cell therapy has been explored for the treatment of cerebral stroke. Several types of stem cells have been investigated to ensure the safety and efficacy in clinical trials.Cryopreserved umbilical cord blood (UCB) mononuclear cells (MNCs) obtained from healthy donors have a more stabilized quality, thereby ensuring a successful therapy. A phase I study was conducted on patients aged 45-80 years who sustained acute ischemic stroke. An UCB unit was obtained from a public cord blood bank based on ABO/Rh blood type, HLA matching scor...
Source: Cell Transplantation - December 23, 2021 Category: Cytology Authors: Tian-Kuo Lee Cheng-You Lu Sheng-Tzung Tsai Pao-Hui Tseng Yu-Chen Lin Shinn-Zong Lin Jonas C Wang Chih-Yang Huang Tsung-Lang Chiu Source Type: research

Evaluation of the Clinical Efficacy of Stem Cell Transplantation in the Treatment of Spinal Cord Injury: A Systematic Review and Meta-analysis
Cell Transplant. 2021 Jan-Dec;30:9636897211067804. doi: 10.1177/09636897211067804.ABSTRACTStem cell transplantation has been applied to treat spinal cord injury (SCI) in clinical trials for many years. However, the clinical efficacies of stem cell transplantation in SCI have been quite diverse. The purpose of our study was to systematically investigate the efficacy of stem cell transplantation in patients with SCI. The PubMed, Web of Science, Ovid-Medline, Cochrane Library, China National Knowledge Infrastructure, VIP, Wanfang, and SinoMed databases were searched until October 27, 2020. Quantitative and qualitative data we...
Source: Cell Transplantation - December 23, 2021 Category: Cytology Authors: Qiao-Rui Tang Hui Xue Qiao Zhang Ying Guo Hao Xu Ying Liu Jia-Mei Liu Source Type: research

Complete Restoration of Motor Function in Acute Cerebral Stroke Treated with Allogeneic Human Umbilical Cord Blood Monocytes: Preliminary Results of a phase I Clinical Trial
Cell Transplant. 2021 Jan-Dec;30:9636897211067447. doi: 10.1177/09636897211067447.ABSTRACTStem cell therapy has been explored for the treatment of cerebral stroke. Several types of stem cells have been investigated to ensure the safety and efficacy in clinical trials.Cryopreserved umbilical cord blood (UCB) mononuclear cells (MNCs) obtained from healthy donors have a more stabilized quality, thereby ensuring a successful therapy. A phase I study was conducted on patients aged 45-80 years who sustained acute ischemic stroke. An UCB unit was obtained from a public cord blood bank based on ABO/Rh blood type, HLA matching scor...
Source: Cell Transplantation - December 23, 2021 Category: Cytology Authors: Tian-Kuo Lee Cheng-You Lu Sheng-Tzung Tsai Pao-Hui Tseng Yu-Chen Lin Shinn-Zong Lin Jonas C Wang Chih-Yang Huang Tsung-Lang Chiu Source Type: research

Evaluation of the Clinical Efficacy of Stem Cell Transplantation in the Treatment of Spinal Cord Injury: A Systematic Review and Meta-analysis
Cell Transplant. 2021 Jan-Dec;30:9636897211067804. doi: 10.1177/09636897211067804.ABSTRACTStem cell transplantation has been applied to treat spinal cord injury (SCI) in clinical trials for many years. However, the clinical efficacies of stem cell transplantation in SCI have been quite diverse. The purpose of our study was to systematically investigate the efficacy of stem cell transplantation in patients with SCI. The PubMed, Web of Science, Ovid-Medline, Cochrane Library, China National Knowledge Infrastructure, VIP, Wanfang, and SinoMed databases were searched until October 27, 2020. Quantitative and qualitative data we...
Source: Cell Transplantation - December 23, 2021 Category: Cytology Authors: Qiao-Rui Tang Hui Xue Qiao Zhang Ying Guo Hao Xu Ying Liu Jia-Mei Liu Source Type: research

Complete Restoration of Motor Function in Acute Cerebral Stroke Treated with Allogeneic Human Umbilical Cord Blood Monocytes: Preliminary Results of a phase I Clinical Trial
Cell Transplant. 2021 Jan-Dec;30:9636897211067447. doi: 10.1177/09636897211067447.ABSTRACTStem cell therapy has been explored for the treatment of cerebral stroke. Several types of stem cells have been investigated to ensure the safety and efficacy in clinical trials.Cryopreserved umbilical cord blood (UCB) mononuclear cells (MNCs) obtained from healthy donors have a more stabilized quality, thereby ensuring a successful therapy. A phase I study was conducted on patients aged 45-80 years who sustained acute ischemic stroke. An UCB unit was obtained from a public cord blood bank based on ABO/Rh blood type, HLA matching scor...
Source: Cell Transplantation - December 23, 2021 Category: Cytology Authors: Tian-Kuo Lee Cheng-You Lu Sheng-Tzung Tsai Pao-Hui Tseng Yu-Chen Lin Shinn-Zong Lin Jonas C Wang Chih-Yang Huang Tsung-Lang Chiu Source Type: research

Evaluation of the Clinical Efficacy of Stem Cell Transplantation in the Treatment of Spinal Cord Injury: A Systematic Review and Meta-analysis
Cell Transplant. 2021 Jan-Dec;30:9636897211067804. doi: 10.1177/09636897211067804.ABSTRACTStem cell transplantation has been applied to treat spinal cord injury (SCI) in clinical trials for many years. However, the clinical efficacies of stem cell transplantation in SCI have been quite diverse. The purpose of our study was to systematically investigate the efficacy of stem cell transplantation in patients with SCI. The PubMed, Web of Science, Ovid-Medline, Cochrane Library, China National Knowledge Infrastructure, VIP, Wanfang, and SinoMed databases were searched until October 27, 2020. Quantitative and qualitative data we...
Source: Cell Transplantation - December 23, 2021 Category: Cytology Authors: Qiao-Rui Tang Hui Xue Qiao Zhang Ying Guo Hao Xu Ying Liu Jia-Mei Liu Source Type: research

Complete Restoration of Motor Function in Acute Cerebral Stroke Treated with Allogeneic Human Umbilical Cord Blood Monocytes: Preliminary Results of a phase I Clinical Trial
Cell Transplant. 2021 Jan-Dec;30:9636897211067447. doi: 10.1177/09636897211067447.ABSTRACTStem cell therapy has been explored for the treatment of cerebral stroke. Several types of stem cells have been investigated to ensure the safety and efficacy in clinical trials.Cryopreserved umbilical cord blood (UCB) mononuclear cells (MNCs) obtained from healthy donors have a more stabilized quality, thereby ensuring a successful therapy. A phase I study was conducted on patients aged 45-80 years who sustained acute ischemic stroke. An UCB unit was obtained from a public cord blood bank based on ABO/Rh blood type, HLA matching scor...
Source: Cell Transplantation - December 23, 2021 Category: Cytology Authors: Tian-Kuo Lee Cheng-You Lu Sheng-Tzung Tsai Pao-Hui Tseng Yu-Chen Lin Shinn-Zong Lin Jonas C Wang Chih-Yang Huang Tsung-Lang Chiu Source Type: research

Evaluation of the Clinical Efficacy of Stem Cell Transplantation in the Treatment of Spinal Cord Injury: A Systematic Review and Meta-analysis
Cell Transplant. 2021 Jan-Dec;30:9636897211067804. doi: 10.1177/09636897211067804.ABSTRACTStem cell transplantation has been applied to treat spinal cord injury (SCI) in clinical trials for many years. However, the clinical efficacies of stem cell transplantation in SCI have been quite diverse. The purpose of our study was to systematically investigate the efficacy of stem cell transplantation in patients with SCI. The PubMed, Web of Science, Ovid-Medline, Cochrane Library, China National Knowledge Infrastructure, VIP, Wanfang, and SinoMed databases were searched until October 27, 2020. Quantitative and qualitative data we...
Source: Cell Transplantation - December 23, 2021 Category: Cytology Authors: Qiao-Rui Tang Hui Xue Qiao Zhang Ying Guo Hao Xu Ying Liu Jia-Mei Liu Source Type: research

Complete Restoration of Motor Function in Acute Cerebral Stroke Treated with Allogeneic Human Umbilical Cord Blood Monocytes: Preliminary Results of a phase I Clinical Trial
Cell Transplant. 2021 Jan-Dec;30:9636897211067447. doi: 10.1177/09636897211067447.ABSTRACTStem cell therapy has been explored for the treatment of cerebral stroke. Several types of stem cells have been investigated to ensure the safety and efficacy in clinical trials.Cryopreserved umbilical cord blood (UCB) mononuclear cells (MNCs) obtained from healthy donors have a more stabilized quality, thereby ensuring a successful therapy. A phase I study was conducted on patients aged 45-80 years who sustained acute ischemic stroke. An UCB unit was obtained from a public cord blood bank based on ABO/Rh blood type, HLA matching scor...
Source: Cell Transplantation - December 23, 2021 Category: Cytology Authors: Tian-Kuo Lee Cheng-You Lu Sheng-Tzung Tsai Pao-Hui Tseng Yu-Chen Lin Shinn-Zong Lin Jonas C Wang Chih-Yang Huang Tsung-Lang Chiu Source Type: research

Evaluation of the Clinical Efficacy of Stem Cell Transplantation in the Treatment of Spinal Cord Injury: A Systematic Review and Meta-analysis
Cell Transplant. 2021 Jan-Dec;30:9636897211067804. doi: 10.1177/09636897211067804.ABSTRACTStem cell transplantation has been applied to treat spinal cord injury (SCI) in clinical trials for many years. However, the clinical efficacies of stem cell transplantation in SCI have been quite diverse. The purpose of our study was to systematically investigate the efficacy of stem cell transplantation in patients with SCI. The PubMed, Web of Science, Ovid-Medline, Cochrane Library, China National Knowledge Infrastructure, VIP, Wanfang, and SinoMed databases were searched until October 27, 2020. Quantitative and qualitative data we...
Source: Cell Transplantation - December 23, 2021 Category: Cytology Authors: Qiao-Rui Tang Hui Xue Qiao Zhang Ying Guo Hao Xu Ying Liu Jia-Mei Liu Source Type: research

Complete Restoration of Motor Function in Acute Cerebral Stroke Treated with Allogeneic Human Umbilical Cord Blood Monocytes: Preliminary Results of a phase I Clinical Trial
Cell Transplant. 2021 Jan-Dec;30:9636897211067447. doi: 10.1177/09636897211067447.ABSTRACTStem cell therapy has been explored for the treatment of cerebral stroke. Several types of stem cells have been investigated to ensure the safety and efficacy in clinical trials.Cryopreserved umbilical cord blood (UCB) mononuclear cells (MNCs) obtained from healthy donors have a more stabilized quality, thereby ensuring a successful therapy. A phase I study was conducted on patients aged 45-80 years who sustained acute ischemic stroke. An UCB unit was obtained from a public cord blood bank based on ABO/Rh blood type, HLA matching scor...
Source: Cell Transplantation - December 23, 2021 Category: Cytology Authors: Tian-Kuo Lee Cheng-You Lu Sheng-Tzung Tsai Pao-Hui Tseng Yu-Chen Lin Shinn-Zong Lin Jonas C Wang Chih-Yang Huang Tsung-Lang Chiu Source Type: research

Evaluation of the Clinical Efficacy of Stem Cell Transplantation in the Treatment of Spinal Cord Injury: A Systematic Review and Meta-analysis
Cell Transplant. 2021 Jan-Dec;30:9636897211067804. doi: 10.1177/09636897211067804.ABSTRACTStem cell transplantation has been applied to treat spinal cord injury (SCI) in clinical trials for many years. However, the clinical efficacies of stem cell transplantation in SCI have been quite diverse. The purpose of our study was to systematically investigate the efficacy of stem cell transplantation in patients with SCI. The PubMed, Web of Science, Ovid-Medline, Cochrane Library, China National Knowledge Infrastructure, VIP, Wanfang, and SinoMed databases were searched until October 27, 2020. Quantitative and qualitative data we...
Source: Cell Transplantation - December 23, 2021 Category: Cytology Authors: Qiao-Rui Tang Hui Xue Qiao Zhang Ying Guo Hao Xu Ying Liu Jia-Mei Liu Source Type: research

Complete Restoration of Motor Function in Acute Cerebral Stroke Treated with Allogeneic Human Umbilical Cord Blood Monocytes: Preliminary Results of a phase I Clinical Trial
Cell Transplant. 2021 Jan-Dec;30:9636897211067447. doi: 10.1177/09636897211067447.ABSTRACTStem cell therapy has been explored for the treatment of cerebral stroke. Several types of stem cells have been investigated to ensure the safety and efficacy in clinical trials.Cryopreserved umbilical cord blood (UCB) mononuclear cells (MNCs) obtained from healthy donors have a more stabilized quality, thereby ensuring a successful therapy. A phase I study was conducted on patients aged 45-80 years who sustained acute ischemic stroke. An UCB unit was obtained from a public cord blood bank based on ABO/Rh blood type, HLA matching scor...
Source: Cell Transplantation - December 23, 2021 Category: Cytology Authors: Tian-Kuo Lee Cheng-You Lu Sheng-Tzung Tsai Pao-Hui Tseng Yu-Chen Lin Shinn-Zong Lin Jonas C Wang Chih-Yang Huang Tsung-Lang Chiu Source Type: research

Genetically Modified Cell Transplantation Through Macroencapsulated Spheroids with Scaffolds to Treat Fabry Disease
In this study, we developed a new ex vivo gene therapy platform using a transplant pack, which consists of a porous membrane made of ethylene-vinyl alcohol in the pack-type and spheroids with scaffolds. These membranes have countless pores of less than 0.1 µm2 capable of secreting proteins, including alpha-galactosidase enzyme, and segregating the contents from the host immune system. When the packs were subcutaneously transplanted into the backs of green fluorescent protein (GFP) mice, no GFP-positive cells migrated to the transplanted pack in either autogenic or allogenic mice. The transplanted cells in the pack su...
Source: Cell Transplantation - December 21, 2021 Category: Cytology Authors: Daisuke Kami Yosuke Suzuki Masashi Yamanami Takahiro Tsukimura Tadayasu Togawa Hitoshi Sakuraba Satoshi Gojo Source Type: research

Genetically Modified Cell Transplantation Through Macroencapsulated Spheroids with Scaffolds to Treat Fabry Disease
In this study, we developed a new ex vivo gene therapy platform using a transplant pack, which consists of a porous membrane made of ethylene-vinyl alcohol in the pack-type and spheroids with scaffolds. These membranes have countless pores of less than 0.1 µm2 capable of secreting proteins, including alpha-galactosidase enzyme, and segregating the contents from the host immune system. When the packs were subcutaneously transplanted into the backs of green fluorescent protein (GFP) mice, no GFP-positive cells migrated to the transplanted pack in either autogenic or allogenic mice. The transplanted cells in the pack su...
Source: Cell Transplantation - December 21, 2021 Category: Cytology Authors: Daisuke Kami Yosuke Suzuki Masashi Yamanami Takahiro Tsukimura Tadayasu Togawa Hitoshi Sakuraba Satoshi Gojo Source Type: research

Genetically Modified Cell Transplantation Through Macroencapsulated Spheroids with Scaffolds to Treat Fabry Disease
In this study, we developed a new ex vivo gene therapy platform using a transplant pack, which consists of a porous membrane made of ethylene-vinyl alcohol in the pack-type and spheroids with scaffolds. These membranes have countless pores of less than 0.1 µm2 capable of secreting proteins, including alpha-galactosidase enzyme, and segregating the contents from the host immune system. When the packs were subcutaneously transplanted into the backs of green fluorescent protein (GFP) mice, no GFP-positive cells migrated to the transplanted pack in either autogenic or allogenic mice. The transplanted cells in the pack su...
Source: Cell Transplantation - December 21, 2021 Category: Cytology Authors: Daisuke Kami Yosuke Suzuki Masashi Yamanami Takahiro Tsukimura Tadayasu Togawa Hitoshi Sakuraba Satoshi Gojo Source Type: research

Corrigendum to "Resveratrol Ameliorates the Malignant Progression of Pancreatic Cancer by Inhibiting Hypoxia-induced Pancreatic Stellate Cell Activation
Cell Transplant. 2021 Jan-Dec;30:9636897211062570. doi: 10.1177/09636897211062570.NO ABSTRACTPMID:34851751 | PMC:PMC8647209 | DOI:10.1177/09636897211062570 (Source: Cell Transplantation)
Source: Cell Transplantation - December 1, 2021 Category: Cytology Source Type: research

Corrigendum to "Resveratrol Ameliorates the Malignant Progression of Pancreatic Cancer by Inhibiting Hypoxia-induced Pancreatic Stellate Cell Activation
Cell Transplant. 2021 Jan-Dec;30:9636897211062570. doi: 10.1177/09636897211062570.NO ABSTRACTPMID:34851751 | PMC:PMC8647209 | DOI:10.1177/09636897211062570 (Source: Cell Transplantation)
Source: Cell Transplantation - December 1, 2021 Category: Cytology Source Type: research

Corrigendum to "Resveratrol Ameliorates the Malignant Progression of Pancreatic Cancer by Inhibiting Hypoxia-induced Pancreatic Stellate Cell Activation
Cell Transplant. 2021 Jan-Dec;30:9636897211062570. doi: 10.1177/09636897211062570.NO ABSTRACTPMID:34851751 | PMC:PMC8647209 | DOI:10.1177/09636897211062570 (Source: Cell Transplantation)
Source: Cell Transplantation - December 1, 2021 Category: Cytology Source Type: research

Corrigendum to "Resveratrol Ameliorates the Malignant Progression of Pancreatic Cancer by Inhibiting Hypoxia-induced Pancreatic Stellate Cell Activation
Cell Transplant. 2021 Jan-Dec;30:9636897211062570. doi: 10.1177/09636897211062570.NO ABSTRACTPMID:34851751 | PMC:PMC8647209 | DOI:10.1177/09636897211062570 (Source: Cell Transplantation)
Source: Cell Transplantation - December 1, 2021 Category: Cytology Source Type: research

Corrigendum to "Resveratrol Ameliorates the Malignant Progression of Pancreatic Cancer by Inhibiting Hypoxia-induced Pancreatic Stellate Cell Activation
Cell Transplant. 2021 Jan-Dec;30:9636897211062570. doi: 10.1177/09636897211062570.NO ABSTRACTPMID:34851751 | PMC:PMC8647209 | DOI:10.1177/09636897211062570 (Source: Cell Transplantation)
Source: Cell Transplantation - December 1, 2021 Category: Cytology Source Type: research

Corrigendum to "Resveratrol Ameliorates the Malignant Progression of Pancreatic Cancer by Inhibiting Hypoxia-induced Pancreatic Stellate Cell Activation
Cell Transplant. 2021 Jan-Dec;30:9636897211062570. doi: 10.1177/09636897211062570.NO ABSTRACTPMID:34851751 | PMC:PMC8647209 | DOI:10.1177/09636897211062570 (Source: Cell Transplantation)
Source: Cell Transplantation - December 1, 2021 Category: Cytology Source Type: research

Corrigendum to "Resveratrol Ameliorates the Malignant Progression of Pancreatic Cancer by Inhibiting Hypoxia-induced Pancreatic Stellate Cell Activation
Cell Transplant. 2021 Jan-Dec;30:9636897211062570. doi: 10.1177/09636897211062570.NO ABSTRACTPMID:34851751 | PMC:PMC8647209 | DOI:10.1177/09636897211062570 (Source: Cell Transplantation)
Source: Cell Transplantation - December 1, 2021 Category: Cytology Source Type: research

Corrigendum to "Resveratrol Ameliorates the Malignant Progression of Pancreatic Cancer by Inhibiting Hypoxia-induced Pancreatic Stellate Cell Activation
Cell Transplant. 2021 Jan-Dec;30:9636897211062570. doi: 10.1177/09636897211062570.NO ABSTRACTPMID:34851751 | PMC:PMC8647209 | DOI:10.1177/09636897211062570 (Source: Cell Transplantation)
Source: Cell Transplantation - December 1, 2021 Category: Cytology Source Type: research

Corrigendum to "Resveratrol Ameliorates the Malignant Progression of Pancreatic Cancer by Inhibiting Hypoxia-induced Pancreatic Stellate Cell Activation
Cell Transplant. 2021 Jan-Dec;30:9636897211062570. doi: 10.1177/09636897211062570.NO ABSTRACTPMID:34851751 | PMC:PMC8647209 | DOI:10.1177/09636897211062570 (Source: Cell Transplantation)
Source: Cell Transplantation - December 1, 2021 Category: Cytology Source Type: research

Corrigendum to "Resveratrol Ameliorates the Malignant Progression of Pancreatic Cancer by Inhibiting Hypoxia-induced Pancreatic Stellate Cell Activation
Cell Transplant. 2021 Jan-Dec;30:9636897211062570. doi: 10.1177/09636897211062570.NO ABSTRACTPMID:34851751 | PMC:PMC8647209 | DOI:10.1177/09636897211062570 (Source: Cell Transplantation)
Source: Cell Transplantation - December 1, 2021 Category: Cytology Source Type: research

Corrigendum to "Resveratrol Ameliorates the Malignant Progression of Pancreatic Cancer by Inhibiting Hypoxia-induced Pancreatic Stellate Cell Activation
Cell Transplant. 2021 Jan-Dec;30:9636897211062570. doi: 10.1177/09636897211062570.NO ABSTRACTPMID:34851751 | PMC:PMC8647209 | DOI:10.1177/09636897211062570 (Source: Cell Transplantation)
Source: Cell Transplantation - December 1, 2021 Category: Cytology Source Type: research

Corrigendum to "Resveratrol Ameliorates the Malignant Progression of Pancreatic Cancer by Inhibiting Hypoxia-induced Pancreatic Stellate Cell Activation
Cell Transplant. 2021 Jan-Dec;30:9636897211062570. doi: 10.1177/09636897211062570.NO ABSTRACTPMID:34851751 | DOI:10.1177/09636897211062570 (Source: Cell Transplantation)
Source: Cell Transplantation - December 1, 2021 Category: Cytology Source Type: research

Corrigendum to "Resveratrol Ameliorates the Malignant Progression of Pancreatic Cancer by Inhibiting Hypoxia-induced Pancreatic Stellate Cell Activation
Cell Transplant. 2021 Jan-Dec;30:9636897211062570. doi: 10.1177/09636897211062570.NO ABSTRACTPMID:34851751 | DOI:10.1177/09636897211062570 (Source: Cell Transplantation)
Source: Cell Transplantation - December 1, 2021 Category: Cytology Source Type: research

Corrigendum to "Resveratrol Ameliorates the Malignant Progression of Pancreatic Cancer by Inhibiting Hypoxia-induced Pancreatic Stellate Cell Activation
Cell Transplant. 2021 Jan-Dec;30:9636897211062570. doi: 10.1177/09636897211062570.NO ABSTRACTPMID:34851751 | DOI:10.1177/09636897211062570 (Source: Cell Transplantation)
Source: Cell Transplantation - December 1, 2021 Category: Cytology Source Type: research

Corrigendum to "Resveratrol Ameliorates the Malignant Progression of Pancreatic Cancer by Inhibiting Hypoxia-induced Pancreatic Stellate Cell Activation
Cell Transplant. 2021 Jan-Dec;30:9636897211062570. doi: 10.1177/09636897211062570.NO ABSTRACTPMID:34851751 | DOI:10.1177/09636897211062570 (Source: Cell Transplantation)
Source: Cell Transplantation - December 1, 2021 Category: Cytology Source Type: research

Leflunomide Inhibits rat-to-Mouse Cardiac Xenograft Rejection by Suppressing Adaptive Immune Cell Response and NF- κB Signaling Activation
In this study, we systematically investigated the immunosuppressive effect of LEF using a rat-to-mouse heart xenotransplantation model. SD rat xenogeneic hearts were transplanted into C57BL/6 mice, and survived 34.5 days after LEF treatment. In contrast, BALB/c allogeneic hearts were transplanted into C57BL/6 mice, and survived 31 days after LEF treatment. Compared to normal saline treatment, LEF treatment decreased xenoreactive T cells and CD19+ B cells in recipient splenocytes. Most importantly, LEF treatment protected myocardial cells by decreasing xenoreactive T and B cell infiltration, inflammatory gene expression, an...
Source: Cell Transplantation - November 24, 2021 Category: Cytology Authors: Yunhan Ma Baiyi Xie Junjun Guo Yingyu Chen Mengya Zhong Qingru Lin Jianyu Hua Jiaying Zhong Xuewei Luo Guoliang Yan Helong Dai Zhongquan Qi Source Type: research

The Role and Mechanism of Exosomes from Umbilical Cord Mesenchymal Stem Cells in Inducing Osteogenesis and Preventing Osteoporosis
In conclusion, we examined the contribution of osteogenic induction to the function of exosomes secreted by HucMSCs following osteogenic differentiation in vitro and in vivo, and reveal the underlying molecular mechanisms of exosome action during osteoporosis.PMID:34814742 | DOI:10.1177/09636897211057465 (Source: Cell Transplantation)
Source: Cell Transplantation - November 24, 2021 Category: Cytology Authors: Ge Yahao Wang Xinjia Source Type: research

Leflunomide Inhibits rat-to-Mouse Cardiac Xenograft Rejection by Suppressing Adaptive Immune Cell Response and NF- κB Signaling Activation
In this study, we systematically investigated the immunosuppressive effect of LEF using a rat-to-mouse heart xenotransplantation model. SD rat xenogeneic hearts were transplanted into C57BL/6 mice, and survived 34.5 days after LEF treatment. In contrast, BALB/c allogeneic hearts were transplanted into C57BL/6 mice, and survived 31 days after LEF treatment. Compared to normal saline treatment, LEF treatment decreased xenoreactive T cells and CD19+ B cells in recipient splenocytes. Most importantly, LEF treatment protected myocardial cells by decreasing xenoreactive T and B cell infiltration, inflammatory gene expression, an...
Source: Cell Transplantation - November 24, 2021 Category: Cytology Authors: Yunhan Ma Baiyi Xie Junjun Guo Yingyu Chen Mengya Zhong Qingru Lin Jianyu Hua Jiaying Zhong Xuewei Luo Guoliang Yan Helong Dai Zhongquan Qi Source Type: research

The Role and Mechanism of Exosomes from Umbilical Cord Mesenchymal Stem Cells in Inducing Osteogenesis and Preventing Osteoporosis
In conclusion, we examined the contribution of osteogenic induction to the function of exosomes secreted by HucMSCs following osteogenic differentiation in vitro and in vivo, and reveal the underlying molecular mechanisms of exosome action during osteoporosis.PMID:34814742 | DOI:10.1177/09636897211057465 (Source: Cell Transplantation)
Source: Cell Transplantation - November 24, 2021 Category: Cytology Authors: Ge Yahao Wang Xinjia Source Type: research

Leflunomide Inhibits rat-to-Mouse Cardiac Xenograft Rejection by Suppressing Adaptive Immune Cell Response and NF- κB Signaling Activation
In this study, we systematically investigated the immunosuppressive effect of LEF using a rat-to-mouse heart xenotransplantation model. SD rat xenogeneic hearts were transplanted into C57BL/6 mice, and survived 34.5 days after LEF treatment. In contrast, BALB/c allogeneic hearts were transplanted into C57BL/6 mice, and survived 31 days after LEF treatment. Compared to normal saline treatment, LEF treatment decreased xenoreactive T cells and CD19+ B cells in recipient splenocytes. Most importantly, LEF treatment protected myocardial cells by decreasing xenoreactive T and B cell infiltration, inflammatory gene expression, an...
Source: Cell Transplantation - November 24, 2021 Category: Cytology Authors: Yunhan Ma Baiyi Xie Junjun Guo Yingyu Chen Mengya Zhong Qingru Lin Jianyu Hua Jiaying Zhong Xuewei Luo Guoliang Yan Helong Dai Zhongquan Qi Source Type: research

The Role and Mechanism of Exosomes from Umbilical Cord Mesenchymal Stem Cells in Inducing Osteogenesis and Preventing Osteoporosis
In conclusion, we examined the contribution of osteogenic induction to the function of exosomes secreted by HucMSCs following osteogenic differentiation in vitro and in vivo, and reveal the underlying molecular mechanisms of exosome action during osteoporosis.PMID:34814742 | DOI:10.1177/09636897211057465 (Source: Cell Transplantation)
Source: Cell Transplantation - November 24, 2021 Category: Cytology Authors: Ge Yahao Wang Xinjia Source Type: research