Enhanced IL-10 inhibits proliferation and promotes apoptosis of HUVECs through STAT3 signaling pathway in sepsis
CONCLUSIONS: The present study demonstrates that the content of IL-10 and the ratio of IL-10+ T cells in peripheral blood of patients with sepsis are up-regulated, and this inhibits HUVEC proliferation and promotes HUVEC apoptosis through STAT3 sig-naling pathway. The results in this study provide a new experimental basis for further understanding the molecular mechanism of sepsis-induced vascular injury.PMID:34528700 | DOI:10.14670/HH-18-375 (Source: Histology and Histopathology)
Source: Histology and Histopathology - September 16, 2021 Category: Cytology Authors: Zuohua Xie Bing Lin Xinju Jia Ting Su Ying Wei Jiping Tang Chengzhi Yang Chuanbao Cui Jinxiang Liu Source Type: research

Protruding structures with high expression of LGR5 are formed during regrowth phase after chemo-treatment in xenograft model of colorectal adenocarcinoma
In this study, to learn how a tumor recovers the typical tumor structure after structural corruption during chemo-treatment, xenografted tumors originating from a patient-derived xenograft of colorectal cancer (CRC) were analyzed histopathologically over time. There were many Duct (Flattened) at Day 1 (one day after the final administration of Irinotecan), but the ratio of Duct (Columnar) and Cribriform-structures typically found in colorectal adenocarcinoma-increased over time. Finally, at Day 15 (15 days after the final administration of Irinotecan), tumor structure and size were once again the same as in the control gro...
Source: Histology and Histopathology - September 8, 2021 Category: Cytology Authors: Masaki Yamazaki Atsuhiko Kato Noriaki Sawada Takeshi Watanabe Masami Suzuki Source Type: research

Traditional Chinese medicine Yiqi Huoxue recipe attenuates hepatic fibrosis via YAP/TAZ signaling
CONCLUSION: YAP/TAZ signaling plays a role, at least in part, in the anti-fibrotic activity of YQHX. The findings may help to better understand the mechanisms of YQHX in the treatment of liver fibrosis.PMID:34490599 | DOI:10.14670/HH-18-373 (Source: Histology and Histopathology)
Source: Histology and Histopathology - September 7, 2021 Category: Cytology Authors: Wen Zhao Xiaoxiao Zhang Mengmeng Hou Yuguo Zhang Yuhui Tang Lu Li Shiming Dong Lingdi Liu Dandan Zhao Wencong Li Yuemin Nan Source Type: research

LINC00937 suppresses keloid fibroblast proliferation and extracellular matrix deposition by targeting the miR-28-5p/MC1R axis
Histol Histopathol. 2021 Aug 23:18372. doi: 10.14670/HH-18-372. Online ahead of print.ABSTRACTLong noncoding RNAs (lncRNAs) are the most recently discovered class of noncoding RNAs. LncRNAs play a crucial role in multiple disorders. However, the role and mechanism of action of lncRNAs in keloids remain unclear. Here, qRT-PCR and western blotting assays were performed to determine the expression of genes and proteins, respectively. MTT assays were carried out to measure the proliferation of keloid fibroblasts. In addition, a luciferase activity assay was conducted to investigate the relationships between LINC00937 and miR-2...
Source: Histology and Histopathology - September 6, 2021 Category: Cytology Authors: Jing Wan Xiao-Lei He Qi-Chao Jian Zhi-Feng Fan Ying Shi Long-Fei Luo Source Type: research

The differential expression of perilipin-2 in hepatoblastoma and its association with prognosis
In conclusion, perilipin-2 is differentially expressed in HB and the strong expression of perilipin-2 predicts a better prognosis.PMID:34477212 | DOI:10.14670/HH-18-371 (Source: Histology and Histopathology)
Source: Histology and Histopathology - September 3, 2021 Category: Cytology Authors: Sadafumi Azukisawa Jianbo Zheng Xin Guo Hiroki Ura Yo Niida Tohru Itoh Sohsuke Yamada Source Type: research

Is extracellular matrix (ECM) a promising scaffold biomaterial for bone repair?
Histol Histopathol. 2021 Sep 2:18370. doi: 10.14670/HH-18-370. Online ahead of print.ABSTRACTThe increasing demand for bone grafts and the scarcity of donors worldwide are promoting researchers to seek alternatives. The extracellular matrix (ECM) has been reported to enhance properties of osteoconduction and osteoinduction by simulating the molecular structure of bone and facilitating cell infiltration for bone repair. As one of several novel biomaterials, ECM has many desirable properties, including biocompatibility, bioactivity, and biosafety. Thus, we evaluated whether ECM is a promising scaffold biomaterial for bone re...
Source: Histology and Histopathology - September 2, 2021 Category: Cytology Authors: Ranli Gu Hao Liu Yuan Zhu Xuenan Liu Siyi Wang Yunsong Liu Source Type: research

Routine histopathology of septal myectomy for hypertrophic obstructive cardiomyopathy in a greek cohort
Histol Histopathol. 2021 Jul 30:18369. doi: 10.14670/HH-18-369. Online ahead of print.ABSTRACTHypertrophic cardiomyopathy (HCM) is a diverse inherited disease affecting 1 in 500 individuals irrespective of gender and ethnicity. A fraction of HCM patients will eventually develop drug refractory dynamic obstruction of the left ventricular outflow tract. For such patients, septal myectomy is the procedure of choice to alleviate their symptoms and improve their quality of life. The current histopathological study, the first from the Greek region, aims to examine the hallmark histopathological characteristics of Hypertrophic Ob...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Nikolaos S Ioakeimidis Antonios Pitsis Dimitrios Ntelios Thomas Zegkos Timotheos Kelpis Theodora Papamitsou Despoina Parcharidou Georgios Efthimiadis Soultana Meditskou Source Type: research

The regulatory role of the BDNF/TrkB pathway in organ and tissue fibrosis
Histol Histopathol. 2021 Jul 30:18368. doi: 10.14670/HH-18-368. Online ahead of print.ABSTRACTFibrosis across diverse organ systems is one of the leading causes of morbidity and mortality by inducing progressive architectural remodeling and organ dysfunction. Brain-derived neurotrophic factor (BDNF) and its receptor tyrosine kinase receptor B (TrkB) play crucial roles in regulating neural survival, development, function and plasticity in the central and the peripheral nervous system. Previous studies demonstrated that the BDNF/TrkB pathway is widely distributed in different cell types such as neuron, epithelial cell, hepat...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Peng-Zhou Hang Feng-Qin Ge Pei-Feng Li Jie Liu Hua Zhu Jing Zhao Source Type: research

Routine histopathology of septal myectomy for hypertrophic obstructive cardiomyopathy in a greek cohort
Histol Histopathol. 2021 Jul 30:18369. doi: 10.14670/HH-18-369. Online ahead of print.ABSTRACTHypertrophic cardiomyopathy (HCM) is a diverse inherited disease affecting 1 in 500 individuals irrespective of gender and ethnicity. A fraction of HCM patients will eventually develop drug refractory dynamic obstruction of the left ventricular outflow tract. For such patients, septal myectomy is the procedure of choice to alleviate their symptoms and improve their quality of life. The current histopathological study, the first from the Greek region, aims to examine the hallmark histopathological characteristics of Hypertrophic Ob...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Nikolaos S Ioakeimidis Antonios Pitsis Dimitrios Ntelios Thomas Zegkos Timotheos Kelpis Theodora Papamitsou Despoina Parcharidou Georgios Efthimiadis Soultana Meditskou Source Type: research

The regulatory role of the BDNF/TrkB pathway in organ and tissue fibrosis
Histol Histopathol. 2021 Jul 30:18368. doi: 10.14670/HH-18-368. Online ahead of print.ABSTRACTFibrosis across diverse organ systems is one of the leading causes of morbidity and mortality by inducing progressive architectural remodeling and organ dysfunction. Brain-derived neurotrophic factor (BDNF) and its receptor tyrosine kinase receptor B (TrkB) play crucial roles in regulating neural survival, development, function and plasticity in the central and the peripheral nervous system. Previous studies demonstrated that the BDNF/TrkB pathway is widely distributed in different cell types such as neuron, epithelial cell, hepat...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Peng-Zhou Hang Feng-Qin Ge Pei-Feng Li Jie Liu Hua Zhu Jing Zhao Source Type: research

Routine histopathology of septal myectomy for hypertrophic obstructive cardiomyopathy in a greek cohort
Histol Histopathol. 2021 Jul 30:18369. doi: 10.14670/HH-18-369. Online ahead of print.ABSTRACTHypertrophic cardiomyopathy (HCM) is a diverse inherited disease affecting 1 in 500 individuals irrespective of gender and ethnicity. A fraction of HCM patients will eventually develop drug refractory dynamic obstruction of the left ventricular outflow tract. For such patients, septal myectomy is the procedure of choice to alleviate their symptoms and improve their quality of life. The current histopathological study, the first from the Greek region, aims to examine the hallmark histopathological characteristics of Hypertrophic Ob...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Nikolaos S Ioakeimidis Antonios Pitsis Dimitrios Ntelios Thomas Zegkos Timotheos Kelpis Theodora Papamitsou Despoina Parcharidou Georgios Efthimiadis Soultana Meditskou Source Type: research

The regulatory role of the BDNF/TrkB pathway in organ and tissue fibrosis
Histol Histopathol. 2021 Jul 30:18368. doi: 10.14670/HH-18-368. Online ahead of print.ABSTRACTFibrosis across diverse organ systems is one of the leading causes of morbidity and mortality by inducing progressive architectural remodeling and organ dysfunction. Brain-derived neurotrophic factor (BDNF) and its receptor tyrosine kinase receptor B (TrkB) play crucial roles in regulating neural survival, development, function and plasticity in the central and the peripheral nervous system. Previous studies demonstrated that the BDNF/TrkB pathway is widely distributed in different cell types such as neuron, epithelial cell, hepat...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Peng-Zhou Hang Feng-Qin Ge Pei-Feng Li Jie Liu Hua Zhu Jing Zhao Source Type: research

Routine histopathology of septal myectomy for hypertrophic obstructive cardiomyopathy in a greek cohort
Histol Histopathol. 2021 Jul 30:18369. doi: 10.14670/HH-18-369. Online ahead of print.ABSTRACTHypertrophic cardiomyopathy (HCM) is a diverse inherited disease affecting 1 in 500 individuals irrespective of gender and ethnicity. A fraction of HCM patients will eventually develop drug refractory dynamic obstruction of the left ventricular outflow tract. For such patients, septal myectomy is the procedure of choice to alleviate their symptoms and improve their quality of life. The current histopathological study, the first from the Greek region, aims to examine the hallmark histopathological characteristics of Hypertrophic Ob...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Nikolaos S Ioakeimidis Antonios Pitsis Dimitrios Ntelios Thomas Zegkos Timotheos Kelpis Theodora Papamitsou Despoina Parcharidou Georgios Efthimiadis Soultana Meditskou Source Type: research

The regulatory role of the BDNF/TrkB pathway in organ and tissue fibrosis
Histol Histopathol. 2021 Jul 30:18368. doi: 10.14670/HH-18-368. Online ahead of print.ABSTRACTFibrosis across diverse organ systems is one of the leading causes of morbidity and mortality by inducing progressive architectural remodeling and organ dysfunction. Brain-derived neurotrophic factor (BDNF) and its receptor tyrosine kinase receptor B (TrkB) play crucial roles in regulating neural survival, development, function and plasticity in the central and the peripheral nervous system. Previous studies demonstrated that the BDNF/TrkB pathway is widely distributed in different cell types such as neuron, epithelial cell, hepat...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Peng-Zhou Hang Feng-Qin Ge Pei-Feng Li Jie Liu Hua Zhu Jing Zhao Source Type: research

Routine histopathology of septal myectomy for hypertrophic obstructive cardiomyopathy in a greek cohort
Histol Histopathol. 2021 Jul 30:18369. doi: 10.14670/HH-18-369. Online ahead of print.ABSTRACTHypertrophic cardiomyopathy (HCM) is a diverse inherited disease affecting 1 in 500 individuals irrespective of gender and ethnicity. A fraction of HCM patients will eventually develop drug refractory dynamic obstruction of the left ventricular outflow tract. For such patients, septal myectomy is the procedure of choice to alleviate their symptoms and improve their quality of life. The current histopathological study, the first from the Greek region, aims to examine the hallmark histopathological characteristics of Hypertrophic Ob...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Nikolaos S Ioakeimidis Antonios Pitsis Dimitrios Ntelios Thomas Zegkos Timotheos Kelpis Theodora Papamitsou Despoina Parcharidou Georgios Efthimiadis Soultana Meditskou Source Type: research

The regulatory role of the BDNF/TrkB pathway in organ and tissue fibrosis
Histol Histopathol. 2021 Jul 30:18368. doi: 10.14670/HH-18-368. Online ahead of print.ABSTRACTFibrosis across diverse organ systems is one of the leading causes of morbidity and mortality by inducing progressive architectural remodeling and organ dysfunction. Brain-derived neurotrophic factor (BDNF) and its receptor tyrosine kinase receptor B (TrkB) play crucial roles in regulating neural survival, development, function and plasticity in the central and the peripheral nervous system. Previous studies demonstrated that the BDNF/TrkB pathway is widely distributed in different cell types such as neuron, epithelial cell, hepat...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Peng-Zhou Hang Feng-Qin Ge Pei-Feng Li Jie Liu Hua Zhu Jing Zhao Source Type: research

Routine histopathology of septal myectomy for hypertrophic obstructive cardiomyopathy in a greek cohort
Histol Histopathol. 2021 Jul 30:18369. doi: 10.14670/HH-18-369. Online ahead of print.ABSTRACTHypertrophic cardiomyopathy (HCM) is a diverse inherited disease affecting 1 in 500 individuals irrespective of gender and ethnicity. A fraction of HCM patients will eventually develop drug refractory dynamic obstruction of the left ventricular outflow tract. For such patients, septal myectomy is the procedure of choice to alleviate their symptoms and improve their quality of life. The current histopathological study, the first from the Greek region, aims to examine the hallmark histopathological characteristics of Hypertrophic Ob...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Nikolaos S Ioakeimidis Antonios Pitsis Dimitrios Ntelios Thomas Zegkos Timotheos Kelpis Theodora Papamitsou Despoina Parcharidou Georgios Efthimiadis Soultana Meditskou Source Type: research

The regulatory role of the BDNF/TrkB pathway in organ and tissue fibrosis
Histol Histopathol. 2021 Jul 30:18368. doi: 10.14670/HH-18-368. Online ahead of print.ABSTRACTFibrosis across diverse organ systems is one of the leading causes of morbidity and mortality by inducing progressive architectural remodeling and organ dysfunction. Brain-derived neurotrophic factor (BDNF) and its receptor tyrosine kinase receptor B (TrkB) play crucial roles in regulating neural survival, development, function and plasticity in the central and the peripheral nervous system. Previous studies demonstrated that the BDNF/TrkB pathway is widely distributed in different cell types such as neuron, epithelial cell, hepat...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Peng-Zhou Hang Feng-Qin Ge Pei-Feng Li Jie Liu Hua Zhu Jing Zhao Source Type: research

Routine histopathology of septal myectomy for hypertrophic obstructive cardiomyopathy in a greek cohort
Histol Histopathol. 2021 Jul 30:18369. doi: 10.14670/HH-18-369. Online ahead of print.ABSTRACTHypertrophic cardiomyopathy (HCM) is a diverse inherited disease affecting 1 in 500 individuals irrespective of gender and ethnicity. A fraction of HCM patients will eventually develop drug refractory dynamic obstruction of the left ventricular outflow tract. For such patients, septal myectomy is the procedure of choice to alleviate their symptoms and improve their quality of life. The current histopathological study, the first from the Greek region, aims to examine the hallmark histopathological characteristics of Hypertrophic Ob...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Nikolaos S Ioakeimidis Antonios Pitsis Dimitrios Ntelios Thomas Zegkos Timotheos Kelpis Theodora Papamitsou Despoina Parcharidou Georgios Efthimiadis Soultana Meditskou Source Type: research

The regulatory role of the BDNF/TrkB pathway in organ and tissue fibrosis
Histol Histopathol. 2021 Jul 30:18368. doi: 10.14670/HH-18-368. Online ahead of print.ABSTRACTFibrosis across diverse organ systems is one of the leading causes of morbidity and mortality by inducing progressive architectural remodeling and organ dysfunction. Brain-derived neurotrophic factor (BDNF) and its receptor tyrosine kinase receptor B (TrkB) play crucial roles in regulating neural survival, development, function and plasticity in the central and the peripheral nervous system. Previous studies demonstrated that the BDNF/TrkB pathway is widely distributed in different cell types such as neuron, epithelial cell, hepat...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Peng-Zhou Hang Feng-Qin Ge Pei-Feng Li Jie Liu Hua Zhu Jing Zhao Source Type: research

Routine histopathology of septal myectomy for hypertrophic obstructive cardiomyopathy in a greek cohort
Histol Histopathol. 2021 Jul 30:18369. doi: 10.14670/HH-18-369. Online ahead of print.ABSTRACTHypertrophic cardiomyopathy (HCM) is a diverse inherited disease affecting 1 in 500 individuals irrespective of gender and ethnicity. A fraction of HCM patients will eventually develop drug refractory dynamic obstruction of the left ventricular outflow tract. For such patients, septal myectomy is the procedure of choice to alleviate their symptoms and improve their quality of life. The current histopathological study, the first from the Greek region, aims to examine the hallmark histopathological characteristics of Hypertrophic Ob...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Nikolaos S Ioakeimidis Antonios Pitsis Dimitrios Ntelios Thomas Zegkos Timotheos Kelpis Theodora Papamitsou Despoina Parcharidou Georgios Efthimiadis Soultana Meditskou Source Type: research

The regulatory role of the BDNF/TrkB pathway in organ and tissue fibrosis
Histol Histopathol. 2021 Jul 30:18368. doi: 10.14670/HH-18-368. Online ahead of print.ABSTRACTFibrosis across diverse organ systems is one of the leading causes of morbidity and mortality by inducing progressive architectural remodeling and organ dysfunction. Brain-derived neurotrophic factor (BDNF) and its receptor tyrosine kinase receptor B (TrkB) play crucial roles in regulating neural survival, development, function and plasticity in the central and the peripheral nervous system. Previous studies demonstrated that the BDNF/TrkB pathway is widely distributed in different cell types such as neuron, epithelial cell, hepat...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Peng-Zhou Hang Feng-Qin Ge Pei-Feng Li Jie Liu Hua Zhu Jing Zhao Source Type: research

Routine histopathology of septal myectomy for hypertrophic obstructive cardiomyopathy in a greek cohort
Histol Histopathol. 2021 Jul 30:18369. doi: 10.14670/HH-18-369. Online ahead of print.ABSTRACTHypertrophic cardiomyopathy (HCM) is a diverse inherited disease affecting 1 in 500 individuals irrespective of gender and ethnicity. A fraction of HCM patients will eventually develop drug refractory dynamic obstruction of the left ventricular outflow tract. For such patients, septal myectomy is the procedure of choice to alleviate their symptoms and improve their quality of life. The current histopathological study, the first from the Greek region, aims to examine the hallmark histopathological characteristics of Hypertrophic Ob...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Nikolaos S Ioakeimidis Antonios Pitsis Dimitrios Ntelios Thomas Zegkos Timotheos Kelpis Theodora Papamitsou Despoina Parcharidou Georgios Efthimiadis Soultana Meditskou Source Type: research

The regulatory role of the BDNF/TrkB pathway in organ and tissue fibrosis
Histol Histopathol. 2021 Jul 30:18368. doi: 10.14670/HH-18-368. Online ahead of print.ABSTRACTFibrosis across diverse organ systems is one of the leading causes of morbidity and mortality by inducing progressive architectural remodeling and organ dysfunction. Brain-derived neurotrophic factor (BDNF) and its receptor tyrosine kinase receptor B (TrkB) play crucial roles in regulating neural survival, development, function and plasticity in the central and the peripheral nervous system. Previous studies demonstrated that the BDNF/TrkB pathway is widely distributed in different cell types such as neuron, epithelial cell, hepat...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Peng-Zhou Hang Feng-Qin Ge Pei-Feng Li Jie Liu Hua Zhu Jing Zhao Source Type: research

Routine histopathology of septal myectomy for hypertrophic obstructive cardiomyopathy in a greek cohort
Histol Histopathol. 2021 Jul 30:18369. doi: 10.14670/HH-18-369. Online ahead of print.ABSTRACTHypertrophic cardiomyopathy (HCM) is a diverse inherited disease affecting 1 in 500 individuals irrespective of gender and ethnicity. A fraction of HCM patients will eventually develop drug refractory dynamic obstruction of the left ventricular outflow tract. For such patients, septal myectomy is the procedure of choice to alleviate their symptoms and improve their quality of life. The current histopathological study, the first from the Greek region, aims to examine the hallmark histopathological characteristics of Hypertrophic Ob...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Nikolaos S Ioakeimidis Antonios Pitsis Dimitrios Ntelios Thomas Zegkos Timotheos Kelpis Theodora Papamitsou Despoina Parcharidou Georgios Efthimiadis Soultana Meditskou Source Type: research

The regulatory role of the BDNF/TrkB pathway in organ and tissue fibrosis
Histol Histopathol. 2021 Jul 30:18368. doi: 10.14670/HH-18-368. Online ahead of print.ABSTRACTFibrosis across diverse organ systems is one of the leading causes of morbidity and mortality by inducing progressive architectural remodeling and organ dysfunction. Brain-derived neurotrophic factor (BDNF) and its receptor tyrosine kinase receptor B (TrkB) play crucial roles in regulating neural survival, development, function and plasticity in the central and the peripheral nervous system. Previous studies demonstrated that the BDNF/TrkB pathway is widely distributed in different cell types such as neuron, epithelial cell, hepat...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Peng-Zhou Hang Feng-Qin Ge Pei-Feng Li Jie Liu Hua Zhu Jing Zhao Source Type: research

Routine histopathology of septal myectomy for hypertrophic obstructive cardiomyopathy in a greek cohort
Histol Histopathol. 2021 Jul 30:18369. doi: 10.14670/HH-18-369. Online ahead of print.ABSTRACTHypertrophic cardiomyopathy (HCM) is a diverse inherited disease affecting 1 in 500 individuals irrespective of gender and ethnicity. A fraction of HCM patients will eventually develop drug refractory dynamic obstruction of the left ventricular outflow tract. For such patients, septal myectomy is the procedure of choice to alleviate their symptoms and improve their quality of life. The current histopathological study, the first from the Greek region, aims to examine the hallmark histopathological characteristics of Hypertrophic Ob...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Nikolaos S Ioakeimidis Antonios Pitsis Dimitrios Ntelios Thomas Zegkos Timotheos Kelpis Theodora Papamitsou Despoina Parcharidou Georgios Efthimiadis Soultana Meditskou Source Type: research

The regulatory role of the BDNF/TrkB pathway in organ and tissue fibrosis
Histol Histopathol. 2021 Jul 30:18368. doi: 10.14670/HH-18-368. Online ahead of print.ABSTRACTFibrosis across diverse organ systems is one of the leading causes of morbidity and mortality by inducing progressive architectural remodeling and organ dysfunction. Brain-derived neurotrophic factor (BDNF) and its receptor tyrosine kinase receptor B (TrkB) play crucial roles in regulating neural survival, development, function and plasticity in the central and the peripheral nervous system. Previous studies demonstrated that the BDNF/TrkB pathway is widely distributed in different cell types such as neuron, epithelial cell, hepat...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Peng-Zhou Hang Feng-Qin Ge Pei-Feng Li Jie Liu Hua Zhu Jing Zhao Source Type: research

Routine histopathology of septal myectomy for hypertrophic obstructive cardiomyopathy in a greek cohort
Histol Histopathol. 2021 Jul 30:18369. doi: 10.14670/HH-18-369. Online ahead of print.ABSTRACTHypertrophic cardiomyopathy (HCM) is a diverse inherited disease affecting 1 in 500 individuals irrespective of gender and ethnicity. A fraction of HCM patients will eventually develop drug refractory dynamic obstruction of the left ventricular outflow tract. For such patients, septal myectomy is the procedure of choice to alleviate their symptoms and improve their quality of life. The current histopathological study, the first from the Greek region, aims to examine the hallmark histopathological characteristics of Hypertrophic Ob...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Nikolaos S Ioakeimidis Antonios Pitsis Dimitrios Ntelios Thomas Zegkos Timotheos Kelpis Theodora Papamitsou Despoina Parcharidou Georgios Efthimiadis Soultana Meditskou Source Type: research

The regulatory role of the BDNF/TrkB pathway in organ and tissue fibrosis
Histol Histopathol. 2021 Jul 30:18368. doi: 10.14670/HH-18-368. Online ahead of print.ABSTRACTFibrosis across diverse organ systems is one of the leading causes of morbidity and mortality by inducing progressive architectural remodeling and organ dysfunction. Brain-derived neurotrophic factor (BDNF) and its receptor tyrosine kinase receptor B (TrkB) play crucial roles in regulating neural survival, development, function and plasticity in the central and the peripheral nervous system. Previous studies demonstrated that the BDNF/TrkB pathway is widely distributed in different cell types such as neuron, epithelial cell, hepat...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Peng-Zhou Hang Feng-Qin Ge Pei-Feng Li Jie Liu Hua Zhu Jing Zhao Source Type: research

Routine histopathology of septal myectomy for hypertrophic obstructive cardiomyopathy in a greek cohort
Histol Histopathol. 2021 Jul 30:18369. doi: 10.14670/HH-18-369. Online ahead of print.ABSTRACTHypertrophic cardiomyopathy (HCM) is a diverse inherited disease affecting 1 in 500 individuals irrespective of gender and ethnicity. A fraction of HCM patients will eventually develop drug refractory dynamic obstruction of the left ventricular outflow tract. For such patients, septal myectomy is the procedure of choice to alleviate their symptoms and improve their quality of life. The current histopathological study, the first from the Greek region, aims to examine the hallmark histopathological characteristics of Hypertrophic Ob...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Nikolaos S Ioakeimidis Antonios Pitsis Dimitrios Ntelios Thomas Zegkos Timotheos Kelpis Theodora Papamitsou Despoina Parcharidou Georgios Efthimiadis Soultana Meditskou Source Type: research

The regulatory role of the BDNF/TrkB pathway in organ and tissue fibrosis
Histol Histopathol. 2021 Jul 30:18368. doi: 10.14670/HH-18-368. Online ahead of print.ABSTRACTFibrosis across diverse organ systems is one of the leading causes of morbidity and mortality by inducing progressive architectural remodeling and organ dysfunction. Brain-derived neurotrophic factor (BDNF) and its receptor tyrosine kinase receptor B (TrkB) play crucial roles in regulating neural survival, development, function and plasticity in the central and the peripheral nervous system. Previous studies demonstrated that the BDNF/TrkB pathway is widely distributed in different cell types such as neuron, epithelial cell, hepat...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Peng-Zhou Hang Feng-Qin Ge Pei-Feng Li Jie Liu Hua Zhu Jing Zhao Source Type: research

Routine histopathology of septal myectomy for hypertrophic obstructive cardiomyopathy in a greek cohort
Histol Histopathol. 2021 Jul 30:18369. doi: 10.14670/HH-18-369. Online ahead of print.ABSTRACTHypertrophic cardiomyopathy (HCM) is a diverse inherited disease affecting 1 in 500 individuals irrespective of gender and ethnicity. A fraction of HCM patients will eventually develop drug refractory dynamic obstruction of the left ventricular outflow tract. For such patients, septal myectomy is the procedure of choice to alleviate their symptoms and improve their quality of life. The current histopathological study, the first from the Greek region, aims to examine the hallmark histopathological characteristics of Hypertrophic Ob...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Nikolaos S Ioakeimidis Antonios Pitsis Dimitrios Ntelios Thomas Zegkos Timotheos Kelpis Theodora Papamitsou Despoina Parcharidou Georgios Efthimiadis Soultana Meditskou Source Type: research

The regulatory role of the BDNF/TrkB pathway in organ and tissue fibrosis
Histol Histopathol. 2021 Jul 30:18368. doi: 10.14670/HH-18-368. Online ahead of print.ABSTRACTFibrosis across diverse organ systems is one of the leading causes of morbidity and mortality by inducing progressive architectural remodeling and organ dysfunction. Brain-derived neurotrophic factor (BDNF) and its receptor tyrosine kinase receptor B (TrkB) play crucial roles in regulating neural survival, development, function and plasticity in the central and the peripheral nervous system. Previous studies demonstrated that the BDNF/TrkB pathway is widely distributed in different cell types such as neuron, epithelial cell, hepat...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Peng-Zhou Hang Feng-Qin Ge Pei-Feng Li Jie Liu Hua Zhu Jing Zhao Source Type: research

Routine histopathology of septal myectomy for hypertrophic obstructive cardiomyopathy in a greek cohort
Histol Histopathol. 2021 Jul 30:18369. doi: 10.14670/HH-18-369. Online ahead of print.ABSTRACTHypertrophic cardiomyopathy (HCM) is a diverse inherited disease affecting 1 in 500 individuals irrespective of gender and ethnicity. A fraction of HCM patients will eventually develop drug refractory dynamic obstruction of the left ventricular outflow tract. For such patients, septal myectomy is the procedure of choice to alleviate their symptoms and improve their quality of life. The current histopathological study, the first from the Greek region, aims to examine the hallmark histopathological characteristics of Hypertrophic Ob...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Nikolaos S Ioakeimidis Antonios Pitsis Dimitrios Ntelios Thomas Zegkos Timotheos Kelpis Theodora Papamitsou Despoina Parcharidou Georgios Efthimiadis Soultana Meditskou Source Type: research

The regulatory role of the BDNF/TrkB pathway in organ and tissue fibrosis
Histol Histopathol. 2021 Jul 30:18368. doi: 10.14670/HH-18-368. Online ahead of print.ABSTRACTFibrosis across diverse organ systems is one of the leading causes of morbidity and mortality by inducing progressive architectural remodeling and organ dysfunction. Brain-derived neurotrophic factor (BDNF) and its receptor tyrosine kinase receptor B (TrkB) play crucial roles in regulating neural survival, development, function and plasticity in the central and the peripheral nervous system. Previous studies demonstrated that the BDNF/TrkB pathway is widely distributed in different cell types such as neuron, epithelial cell, hepat...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Peng-Zhou Hang Feng-Qin Ge Pei-Feng Li Jie Liu Hua Zhu Jing Zhao Source Type: research

Routine histopathology of septal myectomy for hypertrophic obstructive cardiomyopathy in a greek cohort
Histol Histopathol. 2021 Jul 30:18369. doi: 10.14670/HH-18-369. Online ahead of print.ABSTRACTHypertrophic cardiomyopathy (HCM) is a diverse inherited disease affecting 1 in 500 individuals irrespective of gender and ethnicity. A fraction of HCM patients will eventually develop drug refractory dynamic obstruction of the left ventricular outflow tract. For such patients, septal myectomy is the procedure of choice to alleviate their symptoms and improve their quality of life. The current histopathological study, the first from the Greek region, aims to examine the hallmark histopathological characteristics of Hypertrophic Ob...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Nikolaos S Ioakeimidis Antonios Pitsis Dimitrios Ntelios Thomas Zegkos Timotheos Kelpis Theodora Papamitsou Despoina Parcharidou Georgios Efthimiadis Soultana Meditskou Source Type: research

The regulatory role of the BDNF/TrkB pathway in organ and tissue fibrosis
Histol Histopathol. 2021 Jul 30:18368. doi: 10.14670/HH-18-368. Online ahead of print.ABSTRACTFibrosis across diverse organ systems is one of the leading causes of morbidity and mortality by inducing progressive architectural remodeling and organ dysfunction. Brain-derived neurotrophic factor (BDNF) and its receptor tyrosine kinase receptor B (TrkB) play crucial roles in regulating neural survival, development, function and plasticity in the central and the peripheral nervous system. Previous studies demonstrated that the BDNF/TrkB pathway is widely distributed in different cell types such as neuron, epithelial cell, hepat...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Peng-Zhou Hang Feng-Qin Ge Pei-Feng Li Jie Liu Hua Zhu Jing Zhao Source Type: research

Routine histopathology of septal myectomy for hypertrophic obstructive cardiomyopathy in a greek cohort
Histol Histopathol. 2021 Jul 30:18369. doi: 10.14670/HH-18-369. Online ahead of print.ABSTRACTHypertrophic cardiomyopathy (HCM) is a diverse inherited disease affecting 1 in 500 individuals irrespective of gender and ethnicity. A fraction of HCM patients will eventually develop drug refractory dynamic obstruction of the left ventricular outflow tract. For such patients, septal myectomy is the procedure of choice to alleviate their symptoms and improve their quality of life. The current histopathological study, the first from the Greek region, aims to examine the hallmark histopathological characteristics of Hypertrophic Ob...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Nikolaos S Ioakeimidis Antonios Pitsis Dimitrios Ntelios Thomas Zegkos Timotheos Kelpis Theodora Papamitsou Despoina Parcharidou Georgios Efthimiadis Soultana Meditskou Source Type: research

The regulatory role of the BDNF/TrkB pathway in organ and tissue fibrosis
Histol Histopathol. 2021 Jul 30:18368. doi: 10.14670/HH-18-368. Online ahead of print.ABSTRACTFibrosis across diverse organ systems is one of the leading causes of morbidity and mortality by inducing progressive architectural remodeling and organ dysfunction. Brain-derived neurotrophic factor (BDNF) and its receptor tyrosine kinase receptor B (TrkB) play crucial roles in regulating neural survival, development, function and plasticity in the central and the peripheral nervous system. Previous studies demonstrated that the BDNF/TrkB pathway is widely distributed in different cell types such as neuron, epithelial cell, hepat...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Peng-Zhou Hang Feng-Qin Ge Pei-Feng Li Jie Liu Hua Zhu Jing Zhao Source Type: research

Routine histopathology of septal myectomy for hypertrophic obstructive cardiomyopathy in a greek cohort
Histol Histopathol. 2021 Jul 30:18369. doi: 10.14670/HH-18-369. Online ahead of print.ABSTRACTHypertrophic cardiomyopathy (HCM) is a diverse inherited disease affecting 1 in 500 individuals irrespective of gender and ethnicity. A fraction of HCM patients will eventually develop drug refractory dynamic obstruction of the left ventricular outflow tract. For such patients, septal myectomy is the procedure of choice to alleviate their symptoms and improve their quality of life. The current histopathological study, the first from the Greek region, aims to examine the hallmark histopathological characteristics of Hypertrophic Ob...
Source: Histology and Histopathology - July 30, 2021 Category: Cytology Authors: Nikolaos S Ioakeimidis Antonios Pitsis Dimitrios Ntelios Thomas Zegkos Timotheos Kelpis Theodora Papamitsou Despoina Parcharidou Georgios Efthimiadis Soultana Meditskou Source Type: research