Urolithin A attenuates bupivacaine-induced neurotoxicity in SH-SY5Y cells by regulating the SIRT1-activated PI3K/AKT pathway
In conclusion, UroA protected SH-SY5Y cells against BUP-induced injuries through PI3K/AKT signaling in a SIRT1-dependent manner.PMID:38587058 | DOI:10.14670/HH-18-737 (Source: Histology and Histopathology)
Source: Histology and Histopathology - April 8, 2024 Category: Cytology Authors: Bin Liu Yuan Wei Source Type: research
NCAPD3 is a prognostic biomarker and is correlated with immune infiltrates in glioma
Histol Histopathol. 2024 Mar 20:18736. doi: 10.14670/HH-18-736. Online ahead of print.ABSTRACTNon-SMC Condensin II Complex Subunit D3 (NCAPD3) has been linked with the genesis and progression of multiple human cancers. Nevertheless, the scientific value and molecular process of NCAPD3 in glioma remain unclear. We explored the level of NCAPD3 expression in pan-cancer by multiple online databases. And we focused on the level and prognostic value of NCAPD3 expression in glioma by immunohistochemistry (IHC) and survival analysis. Meanwhile, we verified the relationship between NCAPD3, biological function and immune infiltratio...
Source: Histology and Histopathology - April 5, 2024 Category: Cytology Authors: Linzhuo Qu Huiying Che Jingyu Zhao Xin Lu Zijun Ren Yu Wu Qian Liu Hongjian Guan Source Type: research
Prevention of colon enlargement by TNF- α antagonist in a streptozotocin-induced diabetic rat model
CONCLUSIONS: TNF-α signaling in the colonic tissue of diabetic rats has a strong effect on tissue remodeling, leading to colon enlargement. TNF-α antagonists may be beneficial in preventing diabetic-related pathology in the colon in combination with anti-diabetic drugs.PMID:38572731 | DOI:10.14670/HH-18-735 (Source: Histology and Histopathology)
Source: Histology and Histopathology - April 4, 2024 Category: Cytology Authors: Tri Agusti Sholikah Dian Eurike Septyaningtrias Yustina Andwi Ari Sumiwi Muthmainah Muthmainah Rina Susilowati Source Type: research
HSP47 expression in the hamster Sertoli cell: An immunohistochemical study
In conclusion, HSP47 expression in Sertoli cells was found for the first time in mammals. Moreover, increased expression seemed to be related to the degree of atrophy of the seminiferous epithelium and to the reversible or non-reversible physiological state of the seminiferous epithelium.PMID:38567534 | DOI:10.14670/HH-18-734 (Source: Histology and Histopathology)
Source: Histology and Histopathology - April 3, 2024 Category: Cytology Authors: Vicente Seco-Rovira Mar ía Isabel Serrano-Sánchez Ester Beltr án-Frutos Jes ús Martínez-Hernández Concepci ón Ferrer Luis Miguel Pastor Source Type: research
The potential of EZH2 expression to facilitate treatment choice in stage II colorectal adenocarcinoma
CONCLUSION: The OS of stage II CRC with high EZH2 expression improved more strikingly with surgery and adjuvant chemotherapy than with surgery alone, which suggests the potential of EZH2 expression as a biomarker to help identify a subgroup of early-stage CRC benefiting from surgery and adjuvant chemotherapy. More large-scale studies are warranted to corroborate this finding and to further evaluate the predictive nature of EZH2.PMID:38567631 | DOI:10.14670/HH-18-732 (Source: Histology and Histopathology)
Source: Histology and Histopathology - April 3, 2024 Category: Cytology Authors: Xiaoqun Zhu Lu He Zhong Zheng Ya Wang Jun Yang Biao Zhang Chaoshan Wang Zhiwen Li Source Type: research
HSP47 expression in the hamster Sertoli cell: An immunohistochemical study
In conclusion, HSP47 expression in Sertoli cells was found for the first time in mammals. Moreover, increased expression seemed to be related to the degree of atrophy of the seminiferous epithelium and to the reversible or non-reversible physiological state of the seminiferous epithelium.PMID:38567534 | DOI:10.14670/HH-18-734 (Source: Histology and Histopathology)
Source: Histology and Histopathology - April 3, 2024 Category: Cytology Authors: Vicente Seco-Rovira Mar ía Isabel Serrano-Sánchez Ester Beltr án-Frutos Jes ús Martínez-Hernández Concepci ón Ferrer Luis Miguel Pastor Source Type: research
The potential of EZH2 expression to facilitate treatment choice in stage II colorectal adenocarcinoma
CONCLUSION: The OS of stage II CRC with high EZH2 expression improved more strikingly with surgery and adjuvant chemotherapy than with surgery alone, which suggests the potential of EZH2 expression as a biomarker to help identify a subgroup of early-stage CRC benefiting from surgery and adjuvant chemotherapy. More large-scale studies are warranted to corroborate this finding and to further evaluate the predictive nature of EZH2.PMID:38567631 | DOI:10.14670/HH-18-732 (Source: Histology and Histopathology)
Source: Histology and Histopathology - April 3, 2024 Category: Cytology Authors: Xiaoqun Zhu Lu He Zhong Zheng Ya Wang Jun Yang Biao Zhang Chaoshan Wang Zhiwen Li Source Type: research
Functional mechanism of baicalein in alleviating severe acute pancreatitis-acute lung injury by blocking the TLR4/MyD88/TRIF signaling pathway
In conclusion, baicalein can inhibit the TLR4/MyD88/TRIF pathway and alleviate inflammatory response and oxidative stress in SAP-ALI rats by upregulating miR-182 and suppressing TLR4, thus ameliorating SAP-ALI.PMID:38557861 | DOI:10.14670/HH-18-733 (Source: Histology and Histopathology)
Source: Histology and Histopathology - April 1, 2024 Category: Cytology Authors: Qingjing Yang Chao Yue Xing Huang Zihe Wang Zhenlu Li Weiming Hu Huimin Lu Source Type: research
Upregulation and epigenetic modification of the creatine transporter SLC6A8 in non-small cell lung cancer
CONCLUSIONS: Our results suggest an important role of creatine and its transport via SLC6A8 in NSCLC.PMID:38529720 | DOI:10.14670/HH-18-731 (Source: Histology and Histopathology)
Source: Histology and Histopathology - March 26, 2024 Category: Cytology Authors: Christiane Kuempers Karoline Schnepf Sebastian Marwitz Christian Watermann Andreas Scheel Rieke N Fischer Ole Ammerpohl Sven Perner Daniel Dr ömann Torsten Goldmann Source Type: research
