The potential of EZH2 expression to facilitate treatment choice in stage II colorectal adenocarcinoma

CONCLUSION: The OS of stage II CRC with high EZH2 expression improved more strikingly with surgery and adjuvant chemotherapy than with surgery alone, which suggests the potential of EZH2 expression as a biomarker to help identify a subgroup of early-stage CRC benefiting from surgery and adjuvant chemotherapy. More large-scale studies are warranted to corroborate this finding and to further evaluate the predictive nature of EZH2.PMID:38567631 | DOI:10.14670/HH-18-732
Source: Histology and Histopathology - Category: Cytology Authors: Source Type: research