Characterization of Fat Used for the Optimization of the Soft Tissue Envelope of the Nose in Rhinoplasty
We report 21 patients who underwent SRP on a voluntary basis. All patients had either thin skin and/or revision SRP with scarring. Macroscopic fat harvested from the periumbilical or rib region was minced and purified. PRF was obtained by centrifugation of autologous whole blood samples and mixed with the fat to form a graft, which was then transferred to the nasal dorsum. Postoperative monitoring of graft survival included sonography and magnetic resonance imaging (MRI) of the nose. The harvested adipose tissue was also analyzed in vitro. In the postoperative follow-up after 1 year, survival of the adipose tissue was demo...
Source: Facial Plastic Surgery - April 30, 2024 Category: Cosmetic Surgery Authors: Storck, Katharina Ussar, Siegfried Kotz, Sebastian Altun, Irem Hu, Fiona Birk, Amelie Veit, Johannes Kovacevic, Milos Tags: Original Research Source Type: research
Dengue-related acute liver failure —A scoping review
AbstractInfection by dengue virus is common in tropical countries. Hepatic involvement in dengue can range from asymptomatic elevation of transaminases to life-threatening acute liver failure (ALF). Dengue-related ALF (DALF) is responsible for significant morbidity and mortality, especially in Southeast Asia. However, there is a scarcity of literature on DALF, necessitating a thorough examination of its clinical determinants and management strategies. All relevant studies related to DALF were reviewed until December 2023. Case reports, case series and studies reporting ALF in dengue infection were included. Demographics, c...
Source: Indian Journal of Gastroenterology - April 30, 2024 Category: Gastroenterology Source Type: research
Pulmonary Alveolar Microlithiasis in a Patient Requiring Allotransplant
A woman in her late-50s with a 3-year history of progressive hypoxemic respiratory failure, severe pulmonary hypertension, and right ventricular dysfunction was referred for lung transplant assessment. She noted persistent cough and dyspnea on exertion. Pulmonary function testing demonstrated a severe restrictive defect. High-resolution computed tomography of the thorax showed bilateral diffuse interlobular and intralobular septal thickening and ground-glass opacities with extensive calcific deposits (Figure 1). (Source: Mayo Clinic Proceedings)
Source: Mayo Clinic Proceedings - April 30, 2024 Category: Internal Medicine Authors: Suhashini Ganapaty, Chi Wan Koo, Ying-Chun Lo Tags: Medical image Source Type: research
Recipient microbiome-related features predicting metabolic improvement following fecal microbiota transplantation in adults with severe obesity and metabolic syndrome: a secondary analysis of a phase 2 clinical trial
Volume 16, Issue 1, January-December 2024 . (Source: Gut Microbes)
Source: Gut Microbes - April 30, 2024 Category: Microbiology Authors: Zhengxiao ZhangValentin MocanuEdward C. DeehanNaomi HotteYuanyuan ZhuShanshan WeiDina H. KaoShahzeer KarmaliDaniel W. BirchJens WalterKaren L. Madsena College of Ocean Food and Biological Engineering, Fujian Provincial Engineering Technology Research Cent Source Type: research
Chimeric Antigen Receptor T-Cell Access in Patients with Relapsed/Refractory Large B-Cell Lymphoma: Association of Access with Social Determinants of Health and Travel Time to Treatment Centers
Large B-cell lymphoma (LBCL) is the most common type of non-Hodgkin lymphoma, with a US incidence rate of 5.5 per 100,000 men and women per year and a 5-year overall survival rate of 64.7%.1 Although two-thirds of patients with LBCL are cured with standard chemoimmunotherapy regimens, 30%-40% of patients will either have progression of disease or relapse after initial response.2,3 (Source: Biology of Blood and Marrow Transplantation)
Source: Biology of Blood and Marrow Transplantation - April 30, 2024 Category: Hematology Authors: Nausheen Ahmed, Fang Sun, Christie Teigland, Karl M. Kilgore, Iman Mohammadi, John Chambers, Christopher Dieyi, Chaoling Feng, Jennifer Osborn, Christine Fu, Usama Gergis Source Type: research
Impact of Early Cytomegalovirus Reactivation after Allogeneic Hematopoietic Stem Cell Transplantation on Relapse in Patients with Myelodysplastic Syndrome: A Nationwide Retrospective Study from Adult Myelodysplastic Syndrome Working Group of the JSTCT
Cytomegalovirus (CMV) reactivation is a well-recognized major complication associated with morbidity and mortality in patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT).1-5 Although different prophylactic and pre-emptive approaches have been developed to manage CMV reactivation in allogeneic HSCT recipients, several studies still emphasized the negative association between CMV reactivation and various post-transplant outcomes, including non-relapse mortality caused by infectious complications or graft-versus-host disease (GVHD) and overall survival. (Source: Biology of Blood and Marrow Transplantation)
Source: Biology of Blood and Marrow Transplantation - April 30, 2024 Category: Hematology Authors: Tatsuya Konishi, Kensuke Matsuda, Hidehiro Itonaga, Noriko Doki, Tetsuya Nishida, Ken-ichi Matsuoka, Takashi Ikeda, Yoshinobu Kanda, Takahiro Fukuda, Junya Kanda, Hirohisa Nakamae, Kazunori Imada, Yasunori Ueda, Tatsuo Ichinohe, Yoshiko Atsuta, Ken Ishiya Source Type: research
Impact of the Addition of Daratumumab to the Standard Bortezomib-Thalidomide-Dexamethasone Regimen on Hematopoietic Stem Cell Mobilization and Collection, Post-Transplant Engraftment and Infectious Complications: A Case-Control Multicentre Real-Life Analy
(Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - April 30, 2024 Category: Hematology Authors: Gianluca Cavallaro Source Type: research
Outcome of Allogeneic Hematopoietic Stem Cell Transplantation in a Child with Myelodysplastic Neoplasm with Complex Karyotype and ETV6 Variant: Challenges in Treatment
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the only treatment with the potential for cure in patients with myelodysplastic neoplasm (MDS). Nevertheless, disease relapse is the main cause of treatment failure. Due to the rarity of childhood MDS (cMDS), there are few studies showing the impact of cytogenetic alterations and genetic variants on outcomes of allo-HSCT, mainly focusing on clonal chromosomal evolution (CCE) during relapse post-transplant. Here, we describe a 3-year-old boy with cMDS-IB, who evolved to MDS/AML. At diagnosis, the patient showed a complex karyotype with chromosomal abnormaliti...
Source: Mediterranean Journal of Hematology and Infectious Diseases - April 30, 2024 Category: Hematology Authors: Elaiza Almeida Ant ônio de Kós , Viviane Lamim Lovatel , Rita de Cássia Barbosa Tavares , Gerson Moura Ferreira , Bernadete Evangelho Gomes, Ana Paula Silva Bueno, Elaine Sobral da Costa , Teresa de Souza Fernandez Source Type: research
Very late onset Post-Transplantation Lymphoproliferative Disorder (PTLD) after haematopoietic stem cell transplant (HCT) – A Clinical Case
(Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - April 30, 2024 Category: Hematology Authors: Sharon Lionel, Liron Barnea Slonim, Guy Hannah, Victoria Potter, Daniele Avenoso Source Type: research
Haploidentical hematopoietic stem cell transplantation for paediatric patients with x-linked lymphoproliferative syndrome
The aim of this study was to investigate the prognostic factors of haploid hematopoietic stem cell transplantation in the treatment of X-linked lymphoproliferative syndrome. Seven children with X-linked lymphoproliferative syndrome diagnosed by XIAP gene analysis were enrolled. The conditioning regimens were tolerated in all seven patients, and the median time of neutrophil engraftment was 10 days (8-13 days), that of platelet engraftment was 21 days (14-24 days). STR-PCR analysis on the peripheral blood cells showed complete donor origins. Four cases developed Grade I acute graft versus host disease (aGVHD), one developed...
Source: Mediterranean Journal of Hematology and Infectious Diseases - April 30, 2024 Category: Hematology Authors: Yuan Sun Source Type: research
First fetus-to-fetus transplant demonstrated in rats
Nature, Published online: 30 April 2024; doi:10.1038/d41586-024-01152-yThe tissue developed into functioning kidneys and produced urine. (Source: Nature AOP)
Source: Nature AOP - April 30, 2024 Category: Research Authors: Smriti Mallapaty Source Type: research
Adipose Tissue-Brain Interactions Modulate an Anorexia-Related Phenotype in Mice
Anorexia nervosa (AN) is characterized by hypophagia, low body weight, and compulsive exercise. The activity-based anorexia (ABA) paradigm induces aspects of AN in rodents. We tested whether transplanting adipose tissue from high fat diet-fed obese mice into normal weight recipient mice would attenuate ABA in recipients. We also assessed whether the effects of transplanted obese fat depend upon hypothalamic AgRP neurons. (Source: Biological Psychiatry)
Source: Biological Psychiatry - April 29, 2024 Category: Psychiatry Authors: Dongmin Yoon, Zhang Jie, Rizaldy Zapata, Imran Kyeso, Eeshi Uppalapati, Stephanie Dulawa Tags: SYMPOSIUM Source Type: research
Hematopoietic Stem Cell Transplantation in Sickle Cell Disease: A Multidimentional Review
Cell Transplant. 2024 Jan-Dec;33:9636897241246351. doi: 10.1177/09636897241246351.ABSTRACTWhile exagamglogene autotemcel (Casgevy) and lovotibeglogene autotemcel (Lyfgenia) have been approved by the US Food and Drug Administration (FDA) as the first cell-based gene therapies for the treatment of patients 12 years of age and older with sickle cell disease (SCD), this treatment is not universally accessible. Allogeneic hematopoietic stem cell transplant (HSCT) has the potential to eradicate the symptoms of patients with SCD, but a significant obstacle in HSCT for SCD is the availability of suitable donors, particularly human...
Source: Cell Transplantation - April 29, 2024 Category: Cytology Authors: Tahereh Rostami Soroush Rad Mohammad Reza Rostami Seied Amirhossein Mirhosseini Hediyeh Alemi Naghmeh Khavandgar Ghasem Janbabai Azadeh Kiumarsi Amir Kasaeian Seied Asadollah Mousavi Source Type: research
Mortality rate after total knee arthroplasty or total hip arthroplasty in patients with a history of liver transplant
World J Orthop. 2024 Apr 18;15(4):310-311. doi: 10.5312/wjo.v15.i4.310. eCollection 2024 Apr 18.ABSTRACTIn this editorial I comment on the article by Ahmed et al published in a recent issue of the World J Orthop 2023; 14: 784-790. It is well known that patients who have undergone a liver transplant (LT) may need to have a total hip arthroplasty (THA) or total knee arthroplasty (TKA) implanted. Ahmed et al stated that the mortality rate in these patients was similar to the one of the general population. However, there are three articles previously published that found higher mortality in LT patients who experienced THA/TKA ...
Source: World Journal of Orthopaedics - April 29, 2024 Category: Orthopaedics Authors: E Carlos Rodriguez-Merchan Source Type: research
