Polio eradication efforts in regions of geopolitical strife: the Boko Haram threat to efforts in sub-Saharan Africa
The World Health Organization aims to eradicate wild poliovirus worldwide by the end of 2018. Cameroon and Nigeria, neighboring countries, have been affected by the terrorist and militant activities of the Islamist sect Boko Haram. Impacted regions are mainly the far North of Cameroon and Northern Nigeria. Targets of Boko Haram aggression in these zones include violence against polio workers, disruption of polio immunization campaigns, with consequent reduced access to health care and immunization. In addition to this significant problem, Northern Nigeria has historically seen rejection of polio virus&n...
Source: African Health Sciences - July 1, 2016 Category: African Health Source Type: research

Calf restoration with asymmetric fat injection in polio sequelae
In this study, lipofilling and liposuction combinations are performed on patients with poliomyelitis sequelae. Volume deficiency is not the only leg problem with polio sequelae, leg length is also a problem. For this reason, the length deficiency must be addressed in order to achieve the desired symmetry. The aim of this study is correcting limb asymmetry by a method addressing both limb length deficiency by heel raise and volume deficiency by injection of fat based on corrected limb length. (Source: Journal of Plastic, Reconstructive and Aesthetic Surgery)
Source: Journal of Plastic, Reconstructive and Aesthetic Surgery - July 1, 2016 Category: Cosmetic Surgery Authors: Memet Yazar, Sevgi Kurt Yazar, Erol Kozanoğlu Source Type: research

Polio infrastructure strengthened disease outbreak preparedness and response in the WHO African Region.
Abstract INTRODUCTION: The continuous deployments of polio resources, infrastructures and systems for responding to other disease outbreaks in many African countries has led to a number of lessons considered as best practice that need to be documented for strengthening preparedness and response activities in future outbreaks. METHODS: We reviewed and documented the influence of polio best practices in outbreak preparedness and response in Angola, Nigeria and Ethiopia. Data from relevant programmes of the WHO African Region were also analyzed to demonstrate clearly the relative contributions of PEI resources a...
Source: Vaccine - July 1, 2016 Category: Allergy & Immunology Authors: Kouadio K, Okeibunor J, Nsubuga P, Mihigo R, Mkanda P Tags: Vaccine Source Type: research

Seroepidemiology: an underused tool for designing and monitoring vaccination programmes in low ‐ and middle‐income countries
Summary Seroepidemiology, the use of data on the prevalence of bio‐markers of infection or vaccination, is a potentially powerful tool to understand the epidemiology of infection before vaccination and to monitor the effectiveness of vaccination programmes. Global and national burden of disease estimates for hepatitis B and rubella are based almost exclusively on serological data. Seroepidemiology has helped in the design of measles, poliomyelitis and rubella elimination programmes, by informing estimates of the required population immunity thresholds for elimination. It contributes to monitoring of these programmes by i...
Source: Tropical Medicine and International Health - July 1, 2016 Category: Tropical Medicine Authors: Felicity T. Cutts, Matt Hanson Tags: Review Source Type: research

Calf restoration with asymmetric fat injection in polio sequelae
In this study, lipofilling and liposuction combinations are performed on patients with poliomyelitis sequelae. Volume deficiency is not the only leg problem with polio sequelae, leg length is also a problem. For this reason, the length deficiency must be addressed in order to achieve the desired symmetry. The aim of this study is correcting limb asymmetry by a method addressing both limb length deficiency by heel raise and volume deficiency by injection of fat based on corrected limb length. (Source: Journal of Plastic, Reconstructive and Aesthetic Surgery)
Source: Journal of Plastic, Reconstructive and Aesthetic Surgery - July 1, 2016 Category: Cosmetic Surgery Authors: Memet Yazar, Sevgi Kurt Yazar, Erol Kozano ğlu Source Type: research

What is happening to patients who have had polio? The role of the patient in assessment and management.
PMID: 27610439 [PubMed - in process] (Source: Australian Family Physician)
Source: Australian Family Physician - July 1, 2016 Category: Primary Care Authors: Cooper MM Tags: Aust Fam Physician Source Type: research

The genetics of post-polio syndrome - much to be unravelled!
PMID: 27834320 [PubMed - in process] (Source: Indian J Med Res)
Source: Indian J Med Res - July 1, 2016 Category: Research Authors: Saraswathy R Tags: Indian J Med Res Source Type: research

Comparison and Contrast of the Elimination Campaigns for Poliomyelitis and Leprosy: Which is More Feasible?
Authors: Malheiro L, Pinto SC, Sarmento A, Santos L Abstract As we approach the third decade since the WHO started addressing the eradication of poliomyelitis and leprosy, a reflection of the previous campaigns efficacy and an evaluation of further elimination feasibility is important to adapt and intensify the next steps. We performed a critical review of the poliomyelitis and leprosy eradication campaigns to evaluate their technical and operational feasibilities. Vaccination and active case search are highly effective tools against poliomyelitis. If political stability and good vaccination coverage is achieved, p...
Source: Acta Medica Portuguesa - June 30, 2016 Category: Journals (General) Tags: Acta Med Port Source Type: research

The predicted persistence and kinetics of antibody decline 9years after pre-school booster vaccination in UK children.
CONCLUSIONS: There is no defined correlate of protection for pertussis. However, the large proportion of participants in this study with undetectable pertussis antibody levels at both measured and predicted timepoints suggests sub-optimal immunity in adolescence. Adding pertussis to the teenage booster for UK children as is done in other countries, would enhance immunity in adolescence. PMID: 27364096 [PubMed - as supplied by publisher] (Source: Vaccine)
Source: Vaccine - June 27, 2016 Category: Allergy & Immunology Authors: Voysey M, Kandasamy R, Yu LM, Baudin M, Sadorge C, Thomas S, John T, Pollard AJ Tags: Vaccine Source Type: research

Enhancing transit polio vaccination in collaboration with targeted stakeholders in Kaduna State, Nigeria: Lessons learnt: 2014-2015.
CONCLUSION: Engagement of targeted stakeholders significantly enhanced transit polio vaccination in Kaduna State, Nigeria. PMID: 27364095 [PubMed - as supplied by publisher] (Source: Vaccine)
Source: Vaccine - June 27, 2016 Category: Allergy & Immunology Authors: Musa A, Abba B, Ningi AM, Gali E, Bawa S, Manneh F, Mkanda P, Banda R, Yehuluashet YG, Tegegne SG, Umeh G, Nsubuga P, Etsano A, Shuaib F, Mohammed A, Vaz RG Tags: Vaccine Source Type: research

Experience of integrating vitamin A supplementation into polio campaigns in the African Region.
DISCUSSION: Given the progress of the polio program, and decreasing campaigns, there is a risk that fewer children will be reached each year with vitamin A supplementation. We recommend that for countries strengthen the integration of vitamin A supplementation with routine immunization services. PMID: 27364094 [PubMed - as supplied by publisher] (Source: Vaccine)
Source: Vaccine - June 27, 2016 Category: Allergy & Immunology Authors: Chehab ET, Anya BM, Onyango AW, Tevi-Benissan MC, Okeibunor J, Mkanda P, Mihigo R Tags: Vaccine Source Type: research

The Perception of Physical Activity in Ambulatory Persons With Late Effects of Polio: A Qualitative Study.
Authors: Winberg C, Carlsson G, Brogårdh C, Lexel J Abstract Maintaining regular physical activity (PA) can be challenging for persons with late effects of polio. This qualitative study of ambulatory persons with late effects of polio explored their perceptions of PA, and facilitators of and barriers to PA. Semistructured interviews were conducted with 15 persons and analyzed with content analysis using the International Classification of Functioning, Disability and Health (ICF) as framework. The participants described positive perceptions of PA and its health benefits. PA was used to prevent further decline ...
Source: Journal of Aging and Physical Activity - June 25, 2016 Category: Geriatrics Tags: J Aging Phys Act Source Type: research

Routine immunization services in Pakistan: seeing beyond the numbers.
Authors: Husain S, Omer SB Abstract Vaccine-preventable diseases continue to be a major cause of morbidity and mortality among children under 5 years of age in Pakistan, and the country remains one of the last reservoirs of polio, posing a threat of viral spread within the region and globally. This structured review describes challenges in the achievement of vaccination targets and identifies arenas for policy and programmatic interventions and future research. Burdened with limited demand and inefficient vaccination services, the recently devolved Expanded Programme on Immunization (EPI) faces multiple hurdles in ...
Source: Eastern Mediterranean Health Journal - June 25, 2016 Category: Middle East Health Tags: East Mediterr Health J Source Type: research

Reaching the unreached with polio vaccine and other child survival interventions through partnership with military in Angola.
CONCLUSION: Military is a potentially productive force that can be used for any development activities in any country. The Angolan experience has demonstrated that it is possible to form a partnership with the military for basic health intervention activities with little training and investment. PMID: 27354259 [PubMed - as supplied by publisher] (Source: Vaccine)
Source: Vaccine - June 25, 2016 Category: Allergy & Immunology Authors: Fekadu L, Okeibunor J, Nsubuga P, Kipela JM, Mkanda P, Mihigo R Tags: Vaccine Source Type: research

Modeling the spread of polio in an IPV-vaccinated population: lessons learned from the 2013 silent outbreak in southern Israel
Polio eradication is an extraordinary globally coordinated health program in terms of its magnitude and reach, leading to the elimination of wild poliovirus (WPV) in most parts of the world. In 2013, a silent ... (Source: BMC Medicine)
Source: BMC Medicine - June 23, 2016 Category: Internal Medicine Authors: Rami Yaari, Ehud Kaliner, Itamar Grotto, Guy Katriel, Jacob Moran-Gilad, Danit Sofer, Ella Mendelson, Elizabeth Miller, Amit Huppert, E. Anis, E. Kopel, Y. Manor, O. Mor, L. Shulman, R. Singer and M. Weil Source Type: research

Switch to Bivalent Oral Polio Vaccine
While 3 wild poliovirus strains—types 1, 2, and 3—have caused worldwide disease, type 2 has not been detected since 1999, and with its elimination confirmed in September 2015, the need to vaccinate against it has abated. In April more than 150 countries and territories switched from using the trivalent oral poliovirus vaccine (OPV), which protects against the 3 strains of wild poliovirus, to the bivalent OPV, which lacks the type 2 strain (http://bit.ly/1SIFoua). These oral vaccines are made with live attenuated polioviruses. (Source: JAMA)
Source: JAMA - June 21, 2016 Category: Journals (General) Source Type: research

Long-term non-invasive ventilation in muscular dystrophy: Trends in use over 25 years in a home ventilation unit.
Abstract Long-term non-invasive ventilation (NIV) was introduced in the 1980s, initially mainly for patients with poliomyelitis, muscular dystrophy (MD) or scoliosis. The obesity-hypoventilation syndrome has since become the commonest reason for referral to most centres providing home-NIV. Patients with MD are numerically a much smaller part of the workload, but as their disease progresses the need for ventilatory support changes and they require regular comprehensive assessment of their condition. We have examined the trend in MD use of home-NIVin our unit over the last 25 years. The number of new referrals appea...
Source: Chronic Respiratory Disease - June 21, 2016 Category: Respiratory Medicine Authors: Kinnear W, Colt J, Watson L, Smith P, Johnson L, Burrows S, Sovani M, Khanna A, Maddison P, Wills A Tags: Chron Respir Dis Source Type: research

Efficacy, Safety, and Pharmacokinetics of a New 10 % Liquid Intravenous Immunoglobulin Containing High Titer Neutralizing Antibody to RSV and Other Respiratory Viruses in Subjects with Primary Immunodeficiency Disease
Conclusions There were zero serious bacterial infections, thus meeting the primary endpoint for this trial. The secondary endpoints including days missed from work due to infection, unscheduled visits to the physician, and days of hospitalization due to infection compared favorably to published reports of other IVIG products. (Source: Journal of Clinical Immunology)
Source: Journal of Clinical Immunology - June 20, 2016 Category: Allergy & Immunology Source Type: research

India to Vaccinate 300,000 Children After Polio Strain Found in Sewage
14 samples collected between January 2015 and May 2016 tested positive for a strain of the virus -- Read more on ScientificAmerican.com (Source: Scientific American)
Source: Scientific American - June 16, 2016 Category: Science Tags: Health Medicine Public Health Source Type: research

Survey of young patients with polio and a foreign background at a Swedish post-polio outpatient clinic
Abstract Nowadays, polio survivors aged under 60 years are non-native Swedes which pose new aspects and challenges to a post-polio outpatient clinic. To analyze the medical data, walking aids, occupational, and family situation in non-native polio survivors aged less than 60 years at a Swedish post-polio outpatient clinic. Retrospective data analysis. Data were retrieved from medical records at the post-polio outpatient clinic. Actual age, age at acute polio infection, walking capacity, pain, concomitant diseases, working and family situation, and ethnical origin were analyzed. Data are presented in numb...
Source: Neurological Sciences - June 14, 2016 Category: Neurology Source Type: research

Profiling the immunity status of children with non-polio acute flaccid paralysis who had not received any doses of oral polio vaccine in the South–South region, Nigeria 2011–2014
To demonstrate the immunity status of children with non-polio acute flaccid paralysis (NP AFP) reported through the AFP surveillance system in the South–South region of Nigeria. (Source: Public Health)
Source: Public Health - June 11, 2016 Category: Global & Universal Authors: B.E. Bassey, R.G. Vaz, F. Braka, W. Komakech, S.T. Maleghemi, G.U. Akpan, A. Okocha-Ejeko Tags: Original Research Source Type: research

Profiling the immunity status of children with non-polio acute flaccid paralysis who had not received any doses of oral polio vaccine in the  South–South region, Nigeria 2011–2014
To demonstrate the immunity status of children with non-polio acute flaccid paralysis (NP AFP) reported through the AFP surveillance system in the South –South region of Nigeria. (Source: Public Health)
Source: Public Health - June 11, 2016 Category: Global & Universal Authors: B.E. Bassey, R.G. Vaz, F. Braka, W. Komakech, S.T. Maleghemi, G.U. Akpan, A. Okocha-Ejeko Tags: Original Research Source Type: research

[Correspondence] Vaccine scandal and crisis in public confidence in China
In March, 2016, a vaccine scandal in Shandong province, eastern China, has led to the deaths of four children. According to state media, the prime culprit, a former pharmacist, was caught delivering vaccines to medical facilities on bicycles without approved storage conditions. The Shandong Food and Drug Administration made public a list of 25 problematic vaccines1—including polio, mumps, rabies, hepatitis B, encephalitis, and meningococcal vaccines—that had been illegally sold in at least 24 provincial areas since 2011. (Source: LANCET)
Source: LANCET - June 10, 2016 Category: Journals (General) Authors: Jie Qiu, Hengjing Hu, Shenghua Zhou, Qiming Liu Tags: Correspondence Source Type: research

Multistakeholder partnerships with the Democratic Peoples' Republic of Korea to improve childhood immunisation: A perspective from global health equity and political determinants of health equity
ConclusionThe VPD‐focused programmatic activities in the DPRK have improved the delivery of childhood immunisation and have created dialogue and contact with the people of the DPRK. These efforts are likely to ameliorate the political isolation of the people of the DPRK and potentially improve global health equity. (Source: Tropical Medicine and International Health)
Source: Tropical Medicine and International Health - June 9, 2016 Category: Tropical Medicine Authors: Hani Kim, Florian Marks, Uros Novakovic, Peter J. Hotez, Robert E. Black Tags: Original Article Source Type: research

Adult vaccination against tetanus and diphtheria: The European perspective.
This article is protected by copyright. All rights reserved. PMID: 27279025 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - June 9, 2016 Category: Allergy & Immunology Authors: Weinberger B Tags: Clin Exp Immunol Source Type: research

Higher Immune Responses Observed in United States Military Personnel Who Received Meningococcal Conjugate Vaccine Concomitantly with Other Vaccines.
This study was a retrospective evaluation of the immunogenicity of a tetravalent meningococcal conjugate vaccine (MenACWY) administered alone (n = 41) or concomitantly with other vaccines (n = 279) to United States military personnel (mean age = 21.6 years) entering the military between 2006 and 2008. Concomitant vaccines included tetanus/diphtheria (Td), inactivated polio vaccine (IPV), hepatitis vaccines, various influenza vaccines, among others; two vaccine groups excluded Tdap and IPV. Immune responses were evaluated in baseline and post-vaccination sera for Neisseria meningitidis serogroups C and Y 1-12 months (mean =...
Source: Clinical and Vaccine Immunology - June 8, 2016 Category: Allergy & Immunology Authors: Broderick MP, Romero-Steiner S, Rajam G, Johnson SE, Milton A, Kim E, Choi LJ, Radin JM, Schmidt DS, Carlone GM, Messonnier N, Faix DJ Tags: Clin Vaccine Immunol Source Type: research

Asymmetrical bone loss in a patient with poliomyelitis: an indication for anti-osteoporotic therapy.
CONCLUSION: Poliomyelitis is an important acquired risk factor for regional osteoporosis. This condition should be detected and treated in this cohort of patients who are clearly at higher risk of fractures. PMID: 27252750 [PubMed] (Source: Clinical Cases in Mineral and Bone Metabolism)
Source: Clinical Cases in Mineral and Bone Metabolism - June 4, 2016 Category: Orthopaedics Tags: Clin Cases Miner Bone Metab Source Type: research

The effect of mass vaccination campaigns against polio on the utilization of routine immunization services: A regression discontinuity design.
CONCLUSIONS: RDD constitutes a promising tool to assess the effects of mass vaccination campaigns on RI services. It could be tested in additional settings, using larger and more precise datasets. It could also be extended to measure the effects of other disease-specific interventions on the functioning of health systems, in particular those that occur at a discrete point in time and/or include age-related eligibility criteria. PMID: 27269060 [PubMed - as supplied by publisher] (Source: Vaccine)
Source: Vaccine - June 3, 2016 Category: Allergy & Immunology Authors: Helleringer S, Asuming PO, Abdelwahab J Tags: Vaccine Source Type: research

Effect of booster doses of poliovirus vaccine in previously vaccinated children, Clinical Trial Results 2013.
CONCLUSION: IPV has shown the ability to efficiently close existing immunity gaps in a vulnerable population of children in rural Pakistan. PMID: 27269054 [PubMed - as supplied by publisher] (Source: Vaccine)
Source: Vaccine - June 3, 2016 Category: Allergy & Immunology Authors: Habib MA, Soofi S, Mach O, Samejo T, Alam D, Bhatti Z, Weldon WC, Oberste MS, Sutter R, Bhutta ZA Tags: Vaccine Source Type: research

A Pioneering Force: The author's mother was widowed with three young children at age 53, but she never let polio compromise her independence.
No abstract available (Source: Neurology Now)
Source: Neurology Now - June 1, 2016 Category: Neurology Tags: Departments: Speak Up Source Type: research

Implementation of coordinated global serotype 2 oral poliovirus vaccine cessation: risks of inadvertent trivalent oral poliovirus vaccine use
The endgame for polio eradication includes coordinated global cessation of oral poliovirus vaccine (OPV), starting with the cessation of vaccine containing OPV serotype 2 (OPV2) by switching all trivalent OPV ... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - June 1, 2016 Category: Infectious Diseases Authors: Radboud J. Duintjer Tebbens, Lee M. Hampton and Kimberly M. Thompson Source Type: research

MRI findings of enteroviral encephalomyelitis
Conclusion Enterovirus encephalomyelitis has characteristic lesion locations in the posterior portions of the brain stem, substantia nigra, dentate nucleus and within the anterior horns of spinal cord. Recognition of these findings in the presence of suggestive clinical presentation can help to establish the diagnosis of enterovirus encephalomyelitis. (Source: The Egyptian Journal of Radiology and Nuclear Medicine)
Source: The Egyptian Journal of Radiology and Nuclear Medicine - June 1, 2016 Category: Nuclear Medicine Source Type: research

Revascularisation and the acute charcot joint
Background: Charcot neuropathy is a progressive condition affecting the soft tissues, bones and joints most commonly within the foot and ankle. It is a rare complication of the neuropathic foot of which diabetes is the leading cause [1]. Other associated conditions include alcoholic neuropathy, polio, leprosy and syphilis. (Source: Foot and Ankle Surgery)
Source: Foot and Ankle Surgery - June 1, 2016 Category: Orthopaedics Authors: J. Giddie, P. Vaughan, V. Thorisdottir Tags: FI2016_DiabetesCharcot_04 Source Type: research

Adult vaccination against tetanus and diphtheria: The European perspective
This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - June 1, 2016 Category: Allergy & Immunology Authors: Birgit Weinberger Tags: Review Source Type: research

Seroepidemiology: an underused tool for designing and monitoring vaccination programs in low and middle‐income countries
This article is protected by copyright. All rights reserved. (Source: Tropical Medicine and International Health)
Source: Tropical Medicine and International Health - June 1, 2016 Category: Tropical Medicine Authors: Felicity T. Cutts, Matt Hanson Tags: Review Article Source Type: research

Revascularisation and the acute charcot joint
Background: Charcot neuropathy is a progressive condition affecting the soft tissues, bones and joints most commonly within the foot and ankle. It is a rare complication of the neuropathic foot of which diabetes is the leading cause [1]. Other associated conditions include alcoholic neuropathy, polio, leprosy and syphilis. (Source: Foot and Ankle Surgery)
Source: Foot and Ankle Surgery - June 1, 2016 Category: Orthopaedics Authors: J. Giddie, P. Vaughan, V. Thorisdottir Tags: FI2016_DiabetesCharcot_04 Source Type: research

Hajj-associated infections.
CONCLUSION: Prevention is based on compulsory meningococcal vaccination, vaccination against seasonal influenza and pneumococcal infections for pilgrims at high risk of contracting the infection, and on vaccination against hepatitis A. Updating immunization for diphtheria/tetanus/poliomyelitis/pertussis and measles/mumps is also crucial and pilgrims must comply with hygiene precautions. PMID: 27230822 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - May 28, 2016 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

The Recent Outbreaks and Reemergence of Polio-Virus in War and Conflict Affected Areas
(Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - May 27, 2016 Category: Infectious Diseases Authors: Luma Akil, H Anwar Ahmad Source Type: research

The recent outbreaks and reemergence of poliovirus in war and conflict-affected areas
Polio is a highly infectious disease caused by poliovirus, a virus that mainly infects young children. It invades the nervous system and may cause total paralysis.1,2 Polio reached epidemic proportions in the early 1900s in countries with relatively high standards of living. Polio was brought under control after the introduction of effective vaccines in the 1950s and 1960s. It was not until the 1970s that polio was recognized as a major problem in developing countries and routine immunization was introduced. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - May 27, 2016 Category: Infectious Diseases Authors: Luma Akil, H. Anwar Ahmad Source Type: research

Implementation of coordinated global serotype 2 oral poliovirus vaccine cessation: risks of potential non-synchronous cessation
The endgame for polio eradication involves coordinated global cessation of oral poliovirus vaccine (OPV) with cessation of serotype 2 OPV (OPV2 cessation) implemented in late April and early May 2016 and cessa... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - May 26, 2016 Category: Infectious Diseases Authors: Radboud J. Duintjer Tebbens, Lee M. Hampton and Kimberly M. Thompson Source Type: research

The fight against polio takes a tragic toll, but it must continue.
Abstract The recent news that seven policemen in Pakistan were killed while guarding polio vaccination workers in Karachi was tragic, especially when we are close to eradicating polio from the only two remaining countries where the virus is considered endemic - Pakistan and Afghanistan. PMID: 27224625 [PubMed - as supplied by publisher] (Source: Nursing Standard)
Source: Nursing Standard - May 25, 2016 Category: Nursing Authors: Hill T Tags: Nurs Stand Source Type: research

[Newsdesk] Polio endgame: overcoming the final barriers
Polio might be wiped out globally by the end of this year; although there is still the hurdle of endemicity in Afghanistan and Pakistan to be overcome. Sanjeet Bagcchi reports. (Source: The Lancet Infectious Diseases)
Source: The Lancet Infectious Diseases - May 24, 2016 Category: Infectious Diseases Authors: Sanjeet Bagcchi Tags: Newsdesk Source Type: research

Maternal Helminth Infection Is Associated With Higher Infant Immunoglobulin A Titers to Antigen in Orally Administered Vaccines
Conclusions. Antenatal maternal helminth infections were not associated with reduced antibody responses to infant vaccines, but rather with modestly increased IgA responses to oral vaccines. (Source: The Journal of Infectious Diseases)
Source: The Journal of Infectious Diseases - May 24, 2016 Category: Infectious Diseases Authors: Clark, C. E., Fay, M. P., Chico, M. E., Sandoval, C. A., Vaca, M. G., Boyd, A., Cooper, P. J., Nutman, T. B. Tags: PATHOGENESIS AND HOST RESPONSE Source Type: research

Outcome after cementless total hip arthroplasty for arthritic hip in patients with residual poliomyelitis: a case series.
CONCLUSIONS: Although the overall result itself is excellent, THA for these patients cannot improve limp, physical activity and mental status. Surgeons should be aware of the change of the inclination of acetabular cup during mobilisation, especially for THA in contralateral hip. PMID: 27229169 [PubMed - as supplied by publisher] (Source: Hip International)
Source: Hip International - May 23, 2016 Category: Orthopaedics Authors: Cho YJ, Lee CH, Chun YS, Rhyu KH Tags: Hip Int Source Type: research

Why a Paper on Anesthesia and Polio in 2016?
PMID: 27195621 [PubMed - in process] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - May 21, 2016 Category: Anesthesiology Authors: Calmes SH Tags: Anesth Analg Source Type: research

Errata: Vol. 65, No. 18.
Authors: Abstract In the report, "Progress Toward Polio Eradication - Worldwide, 2015-2016," on page 471, in Table 2, the title should have read "Number of reported poliovirus cases, by country - worldwide, January 1, 2015-May 4, 2016," and the heading for the second column should have been "2015 (January-December)." PMID: 27197001 [PubMed - as supplied by publisher] (Source: MMWR Morb Mortal Wkl...)
Source: MMWR Morb Mortal Wkl... - May 21, 2016 Category: Epidemiology Tags: MMWR Morb Mortal Wkly Rep Source Type: research

Polio vaccination: preparing for a change of routine
Publication date: Available online 19 May 2016 Source:The Lancet Author(s): Edward P K Parker, Nicholas C Grassly (Source: The Lancet)
Source: The Lancet - May 20, 2016 Category: Journals (General) Source Type: research

Humoral and intestinal immunity induced by new schedules of bivalent oral poliovirus vaccine and one or two doses of inactivated poliovirus vaccine in Latin American infants: an open-label randomised controlled trial
This study is registered with ClinicalTrials.gov, number NCT01831050, and has been completed. Findings Between May 20, 2013, and Aug 15, 2013, 940 eligible infants were enrolled and randomly assigned to the five treatment groups (210 to group 1, 210 to group 2, 100 to group 3, 210 to group 4, and 210 to group 5). One infant in group 1 was not vaccinated because their parents withdrew consent after enrolment and randomisation, so 939 infants actually received the vaccinations. Three doses of bOPV or tOPV elicited type 1 and 3 seroconversion rates of at least 97·7%. Type 2 seroconversion occurred in 19 of 198 infants...
Source: The Lancet - May 20, 2016 Category: Journals (General) Source Type: research

The Role of Childhood Infections and Immunizations on Childhood Rhabdomyosarcoma: A Report From the Children's Oncology Group
ConclusionsThis is the largest study of RMS to date demonstrating a possible protective effect of immunizations against the development of childhood RMS. Further studies are needed to validate our findings. Our findings add to the growing body of literature, suggesting a protective role of routine vaccinations in childhood cancer and specifically in childhood RMS. (Source: Pediatric Blood and Cancer)
Source: Pediatric Blood and Cancer - May 19, 2016 Category: Cancer & Oncology Authors: Hari Sankaran, Heather E. Danysh, Michael E. Scheurer, M. Fatih Okcu, Stephen X. Skapek, Douglas S. Hawkins, Logan G. Spector, Erik B. Erhardt, Seymour Grufferman, Philip J. Lupo Tags: Research Article Source Type: research

[Comment] Polio vaccination: preparing for a change of routine
The Global Polio Eradication Initiative is on the brink of a major milestone. As of April, 2016, the serotype 2 component of oral poliovirus vaccine (OPV) will be removed from all immunisation activities worldwide. This transition, which is the first step in the synchronised withdrawal of all OPV serotypes, is essential to the polio endgame strategy. Although wild type 2 polioviruses have not caused a case of paralytic disease since 1999, vaccine viruses of this serotype have continued to cause rare cases of vaccine-associated paralytic poliomyelitis in OPV recipients or their close contacts,1 and sporadic emergences of ci...
Source: LANCET - May 19, 2016 Category: Journals (General) Authors: Edward P K Parker, Nicholas C Grassly Tags: Comment Source Type: research