Baseline immune states (BIS) associated with vaccine responsiveness and factors that shape the BIS
Semin Immunol. 2023 Sep 15;70:101842. doi: 10.1016/j.smim.2023.101842. Online ahead of print.ABSTRACTVaccines are among the greatest inventions in medicine, leading to the elimination or control of numerous diseases, including smallpox, polio, measles, rubella, and, most recently, COVID-19. Yet, the effectiveness of vaccines varies among individuals. In fact, while some recipients mount a robust response to vaccination that protects them from the disease, others fail to respond. Multiple clinical and epidemiological factors contribute to this heterogeneity in responsiveness. Systems immunology studies fueled by advances in...
Source: Seminars in Immunology - September 17, 2023 Category: Allergy & Immunology Authors: Djamel Nehar-Belaid Mark Sokolowski Sathyabaarathi Ravichandran Jacques Banchereau Damien Chaussabel Duygu Ucar Source Type: research
Baseline immune states (BIS) associated with vaccine responsiveness and factors that shape the BIS
Semin Immunol. 2023 Sep 15;70:101842. doi: 10.1016/j.smim.2023.101842. Online ahead of print.ABSTRACTVaccines are among the greatest inventions in medicine, leading to the elimination or control of numerous diseases, including smallpox, polio, measles, rubella, and, most recently, COVID-19. Yet, the effectiveness of vaccines varies among individuals. In fact, while some recipients mount a robust response to vaccination that protects them from the disease, others fail to respond. Multiple clinical and epidemiological factors contribute to this heterogeneity in responsiveness. Systems immunology studies fueled by advances in...
Source: Seminars in Immunology - September 17, 2023 Category: Allergy & Immunology Authors: Djamel Nehar-Belaid Mark Sokolowski Sathyabaarathi Ravichandran Jacques Banchereau Damien Chaussabel Duygu Ucar Source Type: research
Prevalence and factors associated with pentavalent vaccination: a cross-sectional study in Southern China
ConclusionsThe DTaP-IPV/Hib vaccine coverage rate in Hainan Province remains low. Factors such as lower socioeconomic status, cultural beliefs, concerns about vaccine safety, and cost may hinder caregivers from vaccinating their children. Further measures, such as health education campaigns to raise knowledge and awareness, and encouragement of domestic vaccine innovation, which would reduce out-of-pocket costs, could be implemented to improve the coverage of DTap-IPV/Hib vaccination.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - September 15, 2023 Category: Infectious Diseases Source Type: research
Case Report: ASCENIV use in three young children with immune abnormalities and acute respiratory failure secondary to RSV infection
Respiratory syncytial virus (RSV) is the most common etiology of bronchiolitis in young children. While most children clinically improve with care at home, RSV is the leading cause of hospitalization among infants aged 12 months or less. Common modalities of treatment for children with immune dysregulation include respiratory support and best supportive care, which may include immunoglobulin therapy. All immunoglobulin therapies adhere to Food and Drug Administration (FDA) - established standards for antibodies against measles, polio, and diphtheria, but there are no required standards for problematic respiratory viral pat...
Source: Frontiers in Immunology - September 14, 2023 Category: Allergy & Immunology Source Type: research
Safety and Clinical Benefits of Adacel ® and Adacel®-Polio Vaccination in Pregnancy: A Structured Literature Review
In conclusion, Adacel or Adacel-Polio vaccination in pregnancy is highly effective in protecting young infants from pertussis disease, with a favorabl e safety profile for both pregnant women and their infants. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - September 1, 2023 Category: Infectious Diseases Source Type: research
Lessons learned from the successful polio vaccine experience not learned or applied with the development and implementation of the COVID-19 vaccines
Curr Opin Immunol. 2023 Aug 29;84:102386. doi: 10.1016/j.coi.2023.102386. Online ahead of print.ABSTRACTThe eradication of polio during the latter half of the 20th century can be considered one of the greatest medical triumphs in history. This achievement can be attributed to the development of vaccines that received the public's almost unwavering acceptance of them, especially by parents who had been waiting/hoping for a medical breakthrough that would ensure that their children would not succumb to the devastating effects of infantile paralysis. Sixty years later, the worldwide population was now confronted with an equal...
Source: Current Opinion in Immunology - August 31, 2023 Category: Allergy & Immunology Authors: Charles S Pavia Maria M Plummer Source Type: research
Lessons learned from the successful polio vaccine experience not learned or applied with the development and implementation of the COVID-19 vaccines
Curr Opin Immunol. 2023 Aug 29;84:102386. doi: 10.1016/j.coi.2023.102386. Online ahead of print.ABSTRACTThe eradication of polio during the latter half of the 20th century can be considered one of the greatest medical triumphs in history. This achievement can be attributed to the development of vaccines that received the public's almost unwavering acceptance of them, especially by parents who had been waiting/hoping for a medical breakthrough that would ensure that their children would not succumb to the devastating effects of infantile paralysis. Sixty years later, the worldwide population was now confronted with an equal...
Source: Current Opinion in Immunology - August 31, 2023 Category: Allergy & Immunology Authors: Charles S Pavia Maria M Plummer Source Type: research
Lessons learned from the successful polio vaccine experience not learned or applied with the development and implementation of the COVID-19 vaccines
Curr Opin Immunol. 2023 Aug 29;84:102386. doi: 10.1016/j.coi.2023.102386. Online ahead of print.ABSTRACTThe eradication of polio during the latter half of the 20th century can be considered one of the greatest medical triumphs in history. This achievement can be attributed to the development of vaccines that received the public's almost unwavering acceptance of them, especially by parents who had been waiting/hoping for a medical breakthrough that would ensure that their children would not succumb to the devastating effects of infantile paralysis. Sixty years later, the worldwide population was now confronted with an equal...
Source: Current Opinion in Immunology - August 31, 2023 Category: Allergy & Immunology Authors: Charles S Pavia Maria M Plummer Source Type: research
Lessons learned from the successful polio vaccine experience not learned or applied with the development and implementation of the COVID-19 vaccines
Curr Opin Immunol. 2023 Aug 29;84:102386. doi: 10.1016/j.coi.2023.102386. Online ahead of print.ABSTRACTThe eradication of polio during the latter half of the 20th century can be considered one of the greatest medical triumphs in history. This achievement can be attributed to the development of vaccines that received the public's almost unwavering acceptance of them, especially by parents who had been waiting/hoping for a medical breakthrough that would ensure that their children would not succumb to the devastating effects of infantile paralysis. Sixty years later, the worldwide population was now confronted with an equal...
Source: Current Opinion in Immunology - August 31, 2023 Category: Allergy & Immunology Authors: Charles S Pavia Maria M Plummer Source Type: research
Lessons learned from the successful polio vaccine experience not learned or applied with the development and implementation of the COVID-19 vaccines
Curr Opin Immunol. 2023 Aug 29;84:102386. doi: 10.1016/j.coi.2023.102386. Online ahead of print.ABSTRACTThe eradication of polio during the latter half of the 20th century can be considered one of the greatest medical triumphs in history. This achievement can be attributed to the development of vaccines that received the public's almost unwavering acceptance of them, especially by parents who had been waiting/hoping for a medical breakthrough that would ensure that their children would not succumb to the devastating effects of infantile paralysis. Sixty years later, the worldwide population was now confronted with an equal...
Source: Current Opinion in Immunology - August 31, 2023 Category: Allergy & Immunology Authors: Charles S Pavia Maria M Plummer Source Type: research
Lessons learned from the successful polio vaccine experience not learned or applied with the development and implementation of the COVID-19 vaccines
Curr Opin Immunol. 2023 Aug 29;84:102386. doi: 10.1016/j.coi.2023.102386. Online ahead of print.ABSTRACTThe eradication of polio during the latter half of the 20th century can be considered one of the greatest medical triumphs in history. This achievement can be attributed to the development of vaccines that received the public's almost unwavering acceptance of them, especially by parents who had been waiting/hoping for a medical breakthrough that would ensure that their children would not succumb to the devastating effects of infantile paralysis. Sixty years later, the worldwide population was now confronted with an equal...
Source: Current Opinion in Immunology - August 31, 2023 Category: Allergy & Immunology Authors: Charles S Pavia Maria M Plummer Source Type: research
Lessons learned from the successful polio vaccine experience not learned or applied with the development and implementation of the COVID-19 vaccines
Curr Opin Immunol. 2023 Aug 29;84:102386. doi: 10.1016/j.coi.2023.102386. Online ahead of print.ABSTRACTThe eradication of polio during the latter half of the 20th century can be considered one of the greatest medical triumphs in history. This achievement can be attributed to the development of vaccines that received the public's almost unwavering acceptance of them, especially by parents who had been waiting/hoping for a medical breakthrough that would ensure that their children would not succumb to the devastating effects of infantile paralysis. Sixty years later, the worldwide population was now confronted with an equal...
Source: Current Opinion in Immunology - August 31, 2023 Category: Allergy & Immunology Authors: Charles S Pavia Maria M Plummer Source Type: research
Lessons learned from the successful polio vaccine experience not learned or applied with the development and implementation of the COVID-19 vaccines
Curr Opin Immunol. 2023 Aug 29;84:102386. doi: 10.1016/j.coi.2023.102386. Online ahead of print.ABSTRACTThe eradication of polio during the latter half of the 20th century can be considered one of the greatest medical triumphs in history. This achievement can be attributed to the development of vaccines that received the public's almost unwavering acceptance of them, especially by parents who had been waiting/hoping for a medical breakthrough that would ensure that their children would not succumb to the devastating effects of infantile paralysis. Sixty years later, the worldwide population was now confronted with an equal...
Source: Current Opinion in Immunology - August 31, 2023 Category: Allergy & Immunology Authors: Charles S Pavia Maria M Plummer Source Type: research
Lessons learned from the successful polio vaccine experience not learned or applied with the development and implementation of the COVID-19 vaccines
Curr Opin Immunol. 2023 Aug 29;84:102386. doi: 10.1016/j.coi.2023.102386. Online ahead of print.ABSTRACTThe eradication of polio during the latter half of the 20th century can be considered one of the greatest medical triumphs in history. This achievement can be attributed to the development of vaccines that received the public's almost unwavering acceptance of them, especially by parents who had been waiting/hoping for a medical breakthrough that would ensure that their children would not succumb to the devastating effects of infantile paralysis. Sixty years later, the worldwide population was now confronted with an equal...
Source: Current Opinion in Immunology - August 31, 2023 Category: Allergy & Immunology Authors: Charles S Pavia Maria M Plummer Source Type: research
