Changes in newly notified cases and control of tuberculosis in China: time-series analysis of surveillance data
ConclusionsThe burden of tuberculosis has been on declining throughout China during recent years, but tuberculosis in western China continues to be a public health emergency that needs to be urgently addressed. Effective prevention and control strategies are needed for regions with high disease burdens and those with increasing or unchanging numbers of newly notified and smear-positive cases of tuberculosis. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - February 24, 2021 Category: Infectious Diseases Source Type: research

Detection of Schistosoma mansoni DNA using polymerase chain reaction from serum and dried blood spot card samples of an adult population in North-western Tanzania
AbstractBackgroundReal-time polymerase chain reaction (PCR) is a sensitive and specific method for diagnosing schistosomiasis. However, this method should be performed in a laboratory, usually located distant from the sample collection site. Therefore, it is important to have fast sampling preservation methods, which allow simple transport prior to DNA extraction and amplification. The aim of this study was to verify if blood samples applied to filter paper are suitable for analysis ofSchistosoma mansoni DNA by real-time PCR.MethodsA cross-sectional study was conducted among 100 study participants aged 17 to 70  years...
Source: Infectious Diseases of Poverty - February 23, 2021 Category: Infectious Diseases Source Type: research

Polyparasitism with Schistosoma haematobium, Plasmodium and soil-transmitted helminths in school-aged children in Muyuka –Cameroon following implementation of control measures: a cross sectional study
ConclusionsPolyparasitism is a public health problem in Muyuka with females most at risk. Anaemia prevalence is exacerbated in co- and triple-infections and together with a history of fever are of value in predicting polyparasitism. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - February 17, 2021 Category: Infectious Diseases Source Type: research

A new candidate vaccine for human brucellosis based on influenza viral vectors: a preliminary investigation for the development of an immunization schedule in a guinea pig model
AbstractBackgroundA new candidate vector vaccine against human brucellosis based on recombinant influenza viral vectors (rIVV) subtypes H5N1 expressingBrucella outer membrane protein (Omp) 16, L7/L12, Omp19 or Cu –Zn SOD proteins has been developed. This paper presents the results of the study of protection of the vaccine using on guinea pigs, including various options of administering, dose and frequency. Provided data of the novel vaccine candidate will contribute to its further movement into the preclin ical stage study.MethodsGeneral states of guinea pigs was assessed based on behavior and dynamics of a guinea pi...
Source: Infectious Diseases of Poverty - February 16, 2021 Category: Infectious Diseases Source Type: research

Global burden of active smoking among people living with HIV on antiretroviral therapy: a systematic review and meta-analysis
AbstractBackgroundAlthough the high burden of both active smoking and human immunodeficiency virus (HIV) is clearly known, the relationship between them is still not well characterized. Therefore, we estimated the global prevalence of active smoking in people living with HIV (PLHIV) on antiretroviral therapy (ART) and investigated the association between exposure to active smoking and risk for suboptimal adherence to ART.Main text: We searched PubMed, Embase, and Web of Science to identify articles published until September 19, 2019. Eligible studies reported the prevalence of active smoking in PLHIV on ART or investigated...
Source: Infectious Diseases of Poverty - February 12, 2021 Category: Infectious Diseases Source Type: research

COVID-19 case fatality risk by age and gender in a high testing setting in Latin America: Chile, March –August 2020
ConclusionsSeverity estimates from COVID-19 in Chile suggest that male seniors, especially among those aged  ≥ 70 years, are being disproportionately affected by the pandemic, a finding consistent with other regions. The ongoing pandemic is imposing a high death toll in South America, and Chile has one of the highest reported mortality rates globally thus far. These real-time estimates may help inf orm public health officials' decisions in the region and underscore the need to implement more effective measures to ameliorate fatality. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - February 3, 2021 Category: Infectious Diseases Source Type: research

The new COVID-19 poor and the neglected tropical diseases resurgence
(Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - January 29, 2021 Category: Infectious Diseases Source Type: research

Potentials of marine natural products against malaria, leishmaniasis, and trypanosomiasis parasites: a review of recent articles
ConclusionsIt is crystal clear that marine organisms are a rich source of antiparasitic compounds, such as alkaloids, terpenoids, peptides, polyketides, terpene, coumarins, steroids, fatty acid derivatives, and lactones. The current and future technological innovation in natural products drug discovery will bolster the drug armamentarium for malaria and neglected tropical diseases. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - January 22, 2021 Category: Infectious Diseases Source Type: research

Impact of multiple policy interventions on the screening and diagnosis of drug-resistant tuberculosis patients: a cascade analysis on six prefectures in China
ConclusionsThe introduction of new diagnostics, including RMT, have improved the detection of DR-TB. Prefectures that received support from the Global Fund and the Gates Foundation had better detection of DR-TB. Additionally, the implementation of provincial DR-TB polices led to improvements in the detection of DR-TB across all prefectures. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - January 19, 2021 Category: Infectious Diseases Source Type: research

Incidence and time-varying predictors of HIV and sexually transmitted infections among male sex workers in Mexico City
ConclusionsIncidence of STIs is high among male sex workers in Mexico City. Consistent condom use is an important protective factor for STIs, and should be an important component of interventions to prevent incident infections. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - January 19, 2021 Category: Infectious Diseases Source Type: research

Predictors of malaria rapid diagnostic test positivity in a high burden area of Paletwa Township, Chin State in Western Myanmar
ConclusionsThe results from this study, including a high proportion ofP. falciparum infections, little difference in age, sex, or occupation, suggest that malaria is a major burden for these study villages. Targeted health education campaigns should be introduced to strengthen synchronous diagnosis-seeking behaviors, tighten treatment adherence, receiving a diagnosis after traveling to endemic regions, and using bed nets properly. We suggest increased surveillance, early diagnosis, and treatment efforts to control the disease and then to consider the local elimination. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - January 11, 2021 Category: Infectious Diseases Source Type: research

Accessing the syndemic of COVID-19 and malaria intervention in Africa
ConclusionsBy quantifying the impact of various NPI response to the COVID-19 pandemic on malaria transmission potential, this study provides a way to jointly address the syndemic between COVID-19 and malaria in malaria-endemic countries in Africa. The results suggest that the early intervention of COVID-19 can effectively reduce the scale of the epidemic and mitigate its impact on malaria transmission potential. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - January 7, 2021 Category: Infectious Diseases Source Type: research

Experience and practice of the Emergency Operations Center, Chinese Center for Disease Control and Prevention: a case study of response to the H7N9 outbreak
ConclusionsThe EOC contributes to faster and more efficient responses during emergencies which enable a greater reduction in morbidity and mortality. Compared with the traditional incident response process, under the command and coordination of China CDC ’s EOC, each group involved in the response has a clearer goal, responsibilities and tasks at each stage. Meanwhile, each group also gave full play to its own expertise and advantages. As a whole, incident response tended to be more specialized and precise, which generally improves the efficiency of incident response. However, different countries and regions have dif...
Source: Infectious Diseases of Poverty - January 6, 2021 Category: Infectious Diseases Source Type: research

Risk factors associated with mortality of COVID-19 in 3125 counties of the United States
AbstractBackgroundThe number of cumulative confirmed cases of COVID-19 in the United States has risen sharply since March 2020. A county health ranking and roadmaps program has been established to identify factors associated with disparity in mobility and mortality of COVID-19 in all counties in the United States. The risk factors associated with county-level mortality of COVID-19 with various levels of prevalence are not well understood.MethodsUsing the data obtained from the County Health Rankings and Roadmaps program, this study applied a negative binomial design to the county-level mortality counts of COVID-19 as of Au...
Source: Infectious Diseases of Poverty - January 4, 2021 Category: Infectious Diseases Source Type: research

Efforts to mitigate the economic impact of the COVID-19 pandemic: potential entry points for neglected tropical diseases
ConclusionsThe NTD community, particularly in low- and middle-income countries (LMICs), will need to work quickly, diligently, and in close collaboration with decision-makers and key stakeholders, across sectors at national and international level to secure its position. Doing so might enhance the odds of grasping potential opportunities to access some of the massive resources that are now available in the form of contributions from corporate foundations, trust funds, loans, debt relieve schemes, and other financial mechanisms, as part of the ongoing and future economic development agendas and public health priorities driv...
Source: Infectious Diseases of Poverty - January 4, 2021 Category: Infectious Diseases Source Type: research

Neglected tropical diseases activities in Africa in the COVID-19 era: the need for a “hybrid” approach in COVID-endemic times
AbstractWith the coronavirus disease 2019 (COVID-19) pandemic showing no signs of abating, resuming neglected tropical disease (NTD) activities, particularly mass drug administration (MDA), is vital. Failure to resume activities will not only enhance the risk of NTD transmission, but will fail to leverage behaviour change messaging on the importance of hand and face washing and improved sanitation —a common strategy for several NTDs that also reduces the risk of COVID-19 spread. This so-called “hybrid approach” will demonstrate best practices for mitigating the spread of severe acute respiratory syndrome ...
Source: Infectious Diseases of Poverty - January 4, 2021 Category: Infectious Diseases Source Type: research

Epidemiology of Blastocystis infection from 1990 to 2019 in China
ConclusionsIn recent years, some provinces/regions in China have conducted various molecular epidemiological studies to identify theBlastocystis subtypes. It is important to focus on new subtypes and mixed subtypes of infection, while increasing data on ribosomal alleles. We encourage the scientific community to start research on humans and surrounding animals (including domestic and wild animals) to better understand the possibility ofBlastocystis transmission between humans and animals. We call for action among researchers studying intestinal parasitic diseases (Blastocystis), start drawing the subtype ofBlastocystis and...
Source: Infectious Diseases of Poverty - December 30, 2020 Category: Infectious Diseases Source Type: research

Functional biomarker signatures of circulating T-cells and its association with distinct clinical status of leprosy patients and their respective household contacts
ConclusionsOur data demonstrated that L(PB) displayed enhanced percentage of IFN- γ+, IL-10+ and IL-4+ as compared to L(MB) that presented functional profile mediated by IL-10+ and IL-4+ T-cells and HHC(MB) exhibited enhanced frequency of IFN- γ+ T-cells, contrasting with HHC(PB). Together, our findings provide additional immunological features associated with leprosy and household contacts. These data provide evidence that biomarkers of immune response can be useful complementary diagnostic/prognostic tools as well as insights that household contacts should be monitored to access putative subclinical infection...
Source: Infectious Diseases of Poverty - December 20, 2020 Category: Infectious Diseases Source Type: research

Evaluating the yield of systematic screening for tuberculosis among three priority groups in Ho Chi Minh City, Viet Nam
This study evaluated concurrent screening in multiple target groups using community health workers (CHW).MethodsIn our two-year intervention study lasting from October 2017 to September 2019, CHWs in six districts of Ho Chi Minh City, Viet Nam verbally screened three urban priority groups: (1) household TB contacts; (2) close TB contacts; and (3) residents of urban priority areas without clear documented exposure to TB including hotspots, boarding homes and urban slums. Eligible persons were referred for further screening with chest radiography and follow-on testing with the Xpert MTB/RIF assay. Symptomatic individuals wit...
Source: Infectious Diseases of Poverty - December 9, 2020 Category: Infectious Diseases Source Type: research

Visceral leishmaniasis in northwest China from 2004 to 2018: a spatio-temporal analysis
ConclusionsThe number of VL cases in three regions of western China concentrated on a few of counties. VL in Kashi Prefecture, Xinjiang Uygur Autonomous Region is still serious prevalent, and integrated control measures must be taken in different endemic areas. Our findings will strengthen the VL control programme in China. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - December 3, 2020 Category: Infectious Diseases Source Type: research

Comparison of patients hospitalized with COVID-19, H7N9 and H1N1
AbstractBackgroundThere is an urgent need to better understand the novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), for that the coronavirus disease 2019 (COVID-19) continues to cause considerable morbidity and mortality worldwide. This paper was to differentiate COVID-19 from other respiratory infectious diseases such as avian-origin influenza A (H7N9) and influenza A (H1N1) virus infections.MethodsWe included patients who had been hospitalized with laboratory-confirmed infection by SARS-CoV-2 (n = 83), H7N9 (n = 36), H1N1 (n = 44) viruses. Clinical...
Source: Infectious Diseases of Poverty - December 2, 2020 Category: Infectious Diseases Source Type: research

Seventy years ’ achievements of international cooperation by the National Institute of Parasitic Diseases at the Chinese Center for Disease Control and Prevention
ConclusionsNIPD ’s new tasks will not only continue to promote national control of endemic parasitic infections and disease elimination programs in China, but also play a leading role in global health and disease elimination programs in the future. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - November 30, 2020 Category: Infectious Diseases Source Type: research

Long-lasting microbial larvicides for controlling insecticide resistant and outdoor transmitting vectors: a cost-effective supplement for malaria interventions
AbstractThe issues of pyrethroid resistance and outdoor malaria parasite transmission have prompted the WHO to call for the development and adoption of viable alternative vector control methods. Larval source management is one of the core malaria vector interventions recommended by the Ministry of Health in many African countries, but it is rarely implemented due to concerns on its cost-effectiveness. New long-lasting microbial larvicide can be a promising cost-effective supplement to current vector control and elimination methods because microbial larvicide uses killing mechanisms different from pyrethroids and other chem...
Source: Infectious Diseases of Poverty - November 26, 2020 Category: Infectious Diseases Source Type: research

Increased circulating level of interleukin-6 and CD8 + T cell exhaustion are associated with progression of COVID-19
This study was designed to determine the clinical and epidemiological features of COVID-19 patients associated with the development of pneumonia and factors associated with disease progression.MethodsSeventy consecutive patients with etiologically confirmed COVID-19 admitted to PLA General Hospital in Beijing, China from December 27, 2019 to March 12, 2020 were enrolled in this study and followed-up to March 16, 2020. Differences in clinical and laboratory findings between COVID-19 patients with pneumonia and those without were determined by theχ2 test or the Fisher exact test (categorical variables) and independent gr...
Source: Infectious Diseases of Poverty - November 25, 2020 Category: Infectious Diseases Source Type: research

Malaria epidemiology and stratification of incidence in the malaria elimination setting  in Harari Region, Eastern Ethiopia
ConclusionsIn the Harari Region, malaria morbidity and mortality have been significantly declined. Thus, if this achievement is sustained and scaling-up of the existing malaria prevention and control strategies by focusing on those populations living in the higher malaria transmission districts and sub-districts, planning of malaria elimination from the study area might be feasible. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - November 22, 2020 Category: Infectious Diseases Source Type: research

From control to elimination: a spatial-temporal analysis of malaria along the China-Myanmar border
AbstractBackgroundMalaria cases have declined significantly along the China-Myanmar border in the past 10  years and this region is going through a process from control to elimination. The aim of this study is to investigate the epidemiology of malaria along the border, will identify challenges in the progress from control to elimination.MethodsNational reported malaria cases from China and Myanmar, along with the data of 18 Chinese border counties and 23 townships in Myanmar were obtained from a web-based diseases information reporting system in China and the national malaria control program of Myanmar, respectively....
Source: Infectious Diseases of Poverty - November 19, 2020 Category: Infectious Diseases Source Type: research

Spatial inequality, characteristics of internal migration, and pulmonary tuberculosis in China, 2011 –2017: a spatial analysis
ConclusionsOur study found the spatial inequity between SS  + PTB and internal migration. Internal emigration, urban-to-rural migration and GDP per capita were statistically associated with SS + PTB; the negative association was identified between internal emigration, urban-to-rural migration and SS + PTB. Further, we found those migrants with l ower income and less education, and most of them were from rural households. These findings can help stakeholders to implement effective PTB control strategies for areas at high risk of PTB and those with high rates of internal migration. (...
Source: Infectious Diseases of Poverty - November 19, 2020 Category: Infectious Diseases Source Type: research

Assessing preventive health behaviors from COVID-19: a cross sectional study with health belief model in Golestan Province, Northern of Iran
ConclusionsResults of the present study indicated that female gender, perceived barriers, perceived self-efficacy, fatalistic beliefs, perceived interests, and living in city had the greatest preventive behaviors from COVID-19 respectively. Preventive interventions were necessary among males and villagers. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - November 17, 2020 Category: Infectious Diseases Source Type: research

A comprehensive research agenda for zero leprosy
ConclusionsDeveloping and achieving consensus on the research agenda for zero leprosy is a significant step forward for the leprosy community. In a next step, research programmes must be developed, with individual components of the research agenda requiring distinct expertise, varying in resource needs, and operating over different timescales. Moving toward zero leprosy now requires partner alignment and new investments at all stages of the research process, from discovery to implementation. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - November 12, 2020 Category: Infectious Diseases Source Type: research

High prevalence of Babesia microti in small mammals in Beijing
ConclusionsThis study demonstrated the wide prevalence ofB. microti infection in eight species of small mammals in Beijing, with Kobe-type more prevalent than U.S.-type. This study provides fundamental information for the development of informed prevention and control measures by public health authorities; the data gathered indicates a need for further monitoring of both clinical diseases in individuals presenting with babesiosis-like symptoms, as well as the infection status of ticks in high risk areas. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - November 11, 2020 Category: Infectious Diseases Source Type: research

Comparing the performance of time series models with or without meteorological factors in predicting incident pulmonary tuberculosis in eastern China
ConclusionsOur study revealed a possible link between PTB and meteorological factors. Taking meteorological factors into consideration increased the accuracy of time series models in predicting PTB, and the ARIMAX model was superior to the ARIMA and RNN models in study settings. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - November 5, 2020 Category: Infectious Diseases Source Type: research

A prolonged cholera outbreak caused by drinking contaminated stream water, Kyangwali refugee settlement, Hoima District, Western Uganda: 2018
ConclusionsOur investigation demonstrated that this was a prolonged cholera outbreak that affected four sub-counties and two divisions in Hoima District, and was associated with drinking of contaminated stream water. In addition, tank water also appears to be unsafe. We recommended boiling drinking water, increasing latrine coverage, and provision of safe water by the District and entire High Commission for refugees. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - November 4, 2020 Category: Infectious Diseases Source Type: research

Spatiotemporal dynamics, risk areas and social determinants of dengue in Northeastern Brazil, 2014 –2017: an ecological study
ConclusionsThis study provides information on the spatial dynamics of dengue in northeastern Brazil and its relationship with social determinants and can be used in the formulation of public health policies to reduce the impact of the disease in vulnerable populations. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - November 3, 2020 Category: Infectious Diseases Source Type: research

First detection of F1534C knockdown resistance mutation in Aedes aegypti (Diptera: Culicidae) from Cameroon
ConclusionsThis study revealed the contrasting resistance profiles to insecticides ofAe. aegypti populations in Cameroon suggesting that, instead of a unique nationwide control approach, a regionally adapted strategy will be needed to control this vector. The localised distribution of the F1534Ckdr mutation supports this region-specific control strategy. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - November 2, 2020 Category: Infectious Diseases Source Type: research

Moving from rhetoric to action: how Africa can use scientific evidence to halt the COVID-19 pandemic
AbstractThe ongoing pandemic of the coronavirus disease 2019  has spread rapidly to all countries of the world. Africa is particularly predisposed to an escalation of the pandemic and its negative impact given its weak economy and health systems. In addition, inadequate access to the social determinants of health such as water and sanitation and socio-cultu ral attributes may constrain the implementation of critical preventive measures such as hand washing and social distancing on the continent.Given these facts, the continent needs to focus on targeted and high impact prevention and control strategies and interv...
Source: Infectious Diseases of Poverty - October 28, 2020 Category: Infectious Diseases Source Type: research

Perceived psychosocial health and its sociodemographic correlates in times of the COVID-19 pandemic: a community-based online study in China
ConclusionsMore than one-third of the participants reported worsening in the experience of hopelessness and loneliness, with more than two-fifth of worsening depression during the pandemic compared with before the outbreak. Several socioeconomic and lifestyle factors were found to be associated with the outcome variables, most notably participants' marital status, household income, smoking, alcohol drinking, existing chronic conditions. These findings may be of significance to treat patients and help them recover from the pandemic. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - October 26, 2020 Category: Infectious Diseases Source Type: research

Differences and similarities of high-resolution computed tomography features between pneumocystis pneumonia and cytomegalovirus pneumonia in AIDS patients
AbstractBackgroundAccurately differentiating pneumocystis from cytomegalovirus pneumonia is crucial for correct therapy selection in AIDS patients. Hence, the goal of this study was to compare the computerized tomography (CT) features of pneumocystis pneumonia and cytomegalovirus pneumonia in AIDS patients and identify clinical hallmarks to accurately distinguish these two pathologies.MethodsA total of 112 AIDS patients (78 with pneumocystis pneumonia and 34 cytomegalovirus pneumonia) at Beijing Ditan Hospital from January 2017 to May 2019 were included in this study. Two experienced chest radiologists retrospectively revi...
Source: Infectious Diseases of Poverty - October 26, 2020 Category: Infectious Diseases Source Type: research

Correlates of HIV self-testing among female sex workers in China: implications for expanding HIV screening
ConclusionsOur findings suggest that HIV self-testing could expand overall HIV testing uptake, increase HIV testing frequency, reach sub-groups of high-risk female sex workers and has limited potential harms among female sex workers. HIV self-testing should be incorporated among Chinese female sex workers as a complement to facility-based HIV testing services. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - October 22, 2020 Category: Infectious Diseases Source Type: research

Quantification and correlates of tuberculosis stigma along the tuberculosis testing and treatment cascades in South Africa: a cross-sectional study
ConclusionsTB stigma interventions should be developed for TB presumptives, as stigma may increase initial-loss-to-follow up. Given that stigma may be driven by numerous factors throughout the TB cascade, adaptive stigma reduction interventions may be required. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - October 22, 2020 Category: Infectious Diseases Source Type: research

Spatial and spatio-temporal analysis of malaria cases in Zimbabwe
AbstractBackgroundAlthough effective treatment for malaria is now available, approximately half of the global population remain at risk of the disease particularly in developing countries. To design effective malaria control strategies there is need to understand the pattern of malaria heterogeneity in an area. Therefore, the main objective of this study was to explore the spatial and spatio-temporal pattern of malaria cases in Zimbabwe based on malaria data aggregated at district level from 2011 to 2016.MethodsGeographical information system (GIS) and spatial scan statistic were applied on passive malaria data collected f...
Source: Infectious Diseases of Poverty - October 22, 2020 Category: Infectious Diseases Source Type: research

Costs incurred by patients with drug-susceptible pulmonary tuberculosis in semi-urban and rural settings of Western India
ConclusionsTreatment completion was high and the costs incurred by TB patients were low in this setting. However, negative financial consequences occur even in low-cost settings. The role of universal cash transfer programs in such settings requires further study. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - October 19, 2020 Category: Infectious Diseases Source Type: research

Compare the epidemiological and clinical features of imported and local COVID-19 cases in Hainan, China
We described the epidemiological and clinical characteristics of COVID-19 in Hainan and compared these features between imported and local cases to provide information for other international epidemic areas.MethodsWe included 91 patients (56 imported and 35 local cases) from two designated hospitals for COVID-19 in Haikou, China, from January 20 to February 19, 2020. Data on the demographic, epidemiological, clinical and laboratory characteristics were extracted from medical records. Patients were followed until April 21, 2020, and the levels of antibodies at the follow-ups were also analysed by the Wilcoxon matched-pairs ...
Source: Infectious Diseases of Poverty - October 19, 2020 Category: Infectious Diseases Source Type: research

Human distribution and spatial-temporal clustering analysis of human brucellosis in China from 2012 to 2016
ConclusionsHuman brucellosis remains a widespread challenge, particularly in northern China. The clustering analysis highlights potential high-risk human groups, time frames and areas, which may require special plans and resources to monitor and control the disease. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - October 13, 2020 Category: Infectious Diseases Source Type: research

Effective mitigation strategy in early stage of COVID-19 pandemic in China
AbstractIn the past five months, success in control the national epidemic of coronavirus disease 2019 (COVID-19) has been witnessed in China. The implementation of public health measures accounts for the success which include different interventions in the early or later stages of the outbreak. It is clear that although not all measures were universally effective worldwide, their achievements have been significant. More solidarity is needed to deal with this global pandemic with more learning and understanding. Understanding which of the public health interventions implemented in China were effective may provide ideas for ...
Source: Infectious Diseases of Poverty - October 12, 2020 Category: Infectious Diseases Source Type: research

Towards integrated surveillance-response systems for the prevention of future pandemics
In conclusion, the earlier a zoonotic pathogen can be detected in the environment, in wildlife or in domestic animals; and the better human, animal and environmental surveillance communicate with each other to prevent an outbreak, the lower are the cumulative costs. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - October 6, 2020 Category: Infectious Diseases Source Type: research

Burden, risk assessment, surveillance and management of SARS-CoV-2 infection in health workers: a scoping review
ConclusionsDuring the spread of COVID-19 outbreak, numerous published papers investigated the epidemiology, risk assessment and prevention and control of SARS-CoV-2. However, more high-quality studies are needed to provide valid recommendations for better management and for the clinical and microbiological surveillance of healthcare personnel. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - October 6, 2020 Category: Infectious Diseases Source Type: research

Crowdsourcing to identify social innovation initiatives in health in low- and middle-income countries
ConclusionsWe demonstrate that crowdsourcing is a participatory method, that is able to identify bottom-up or grassroots SI initiatives developed by non-traditional actors. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - October 6, 2020 Category: Infectious Diseases Source Type: research

Progress on the national echinococcosis control programme in China: analysis of humans and dogs population intervention during 2004 –2014
ConclusionsThis study showed that in endemic areas, patient diagnosis and management, dog management and treatment over this period helped reduce the parasite load to control the disease. More attention should be paid to controlling wild canines during the ongoing program period and sustainable follow-up evaluations are crucial for success and continued implementation of the national program. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - October 1, 2020 Category: Infectious Diseases Source Type: research

Surveillance on schistosomiasis in five provincial-level administrative divisions of the People ’s Republic of China in the post-elimination era
ConclusionsElimination of schistosomiasis was consolidated successfully in five PLADs of P. R. China due to effective and strong post-elimination surveillance. Comprehensive consolidation strategies should be focused on the elimination of residual snails and the prevention of imported infection sources to consolidate the achievements of schistosomiasis control. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - September 30, 2020 Category: Infectious Diseases Source Type: research

Cost-effectiveness analysis of malaria rapid diagnostic test in the elimination setting
ConclusionsCompared to microscopy and RDT followed by microscopy, RDT strategy had higher effects and higher cost in the setting of malaria elimination. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - September 28, 2020 Category: Infectious Diseases Source Type: research